FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3427, 425 aa 1>>>pF1KB3427 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0530+/-0.000372; mu= 18.5272+/- 0.023 mean_var=61.0485+/-12.076, 0's: 0 Z-trim(111.8): 23 B-trim: 28 in 1/57 Lambda= 0.164148 statistics sampled from 20525 (20542) to 20525 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.241), width: 16 Scan time: 7.280 The best scores are: opt bits E(85289) NP_001116850 (OMIM: 103050,608222) adenylosuccinat ( 425) 2824 677.5 1.8e-194 XP_011528282 (OMIM: 103050,608222) PREDICTED: aden ( 467) 2784 668.0 1.3e-191 XP_011528281 (OMIM: 103050,608222) PREDICTED: aden ( 480) 2645 635.1 1.1e-181 NP_000017 (OMIM: 103050,608222) adenylosuccinate l ( 484) 2645 635.1 1.1e-181 XP_011528279 (OMIM: 103050,608222) PREDICTED: aden ( 526) 2645 635.2 1.2e-181 NP_001304852 (OMIM: 103050,608222) adenylosuccinat ( 420) 2192 527.8 2e-149 XP_016884126 (OMIM: 103050,608222) PREDICTED: aden ( 469) 1718 415.6 1.3e-115 XP_016884125 (OMIM: 103050,608222) PREDICTED: aden ( 511) 1718 415.6 1.4e-115 XP_016884128 (OMIM: 103050,608222) PREDICTED: aden ( 329) 1548 375.2 1.3e-103 XP_016884127 (OMIM: 103050,608222) PREDICTED: aden ( 371) 1548 375.3 1.4e-103 XP_016884129 (OMIM: 103050,608222) PREDICTED: aden ( 249) 789 195.4 1.3e-49 XP_011542434 (OMIM: 136850,606812) PREDICTED: fuma ( 434) 144 42.8 0.002 NP_000134 (OMIM: 136850,606812) fumarate hydratase ( 510) 144 42.9 0.0023 >>NP_001116850 (OMIM: 103050,608222) adenylosuccinate ly (425 aa) initn: 2824 init1: 2824 opt: 2824 Z-score: 3612.6 bits: 677.5 E(85289): 1.8e-194 Smith-Waterman score: 2824; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK 370 380 390 400 410 420 pF1KB3 AELCL ::::: NP_001 AELCL >>XP_011528282 (OMIM: 103050,608222) PREDICTED: adenylos (467 aa) initn: 2784 init1: 2784 opt: 2784 Z-score: 3560.8 bits: 668.0 E(85289): 1.3e-191 Smith-Waterman score: 2784; 99.8% identity (99.8% similar) in 420 aa overlap (1-420:1-420) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKCK 370 380 390 400 410 420 pF1KB3 AELCL XP_011 QVPLDKNVVCVIPCCISNSKSTSDTWQLGSLPASATAPDFLVAWIYS 430 440 450 460 >>XP_011528281 (OMIM: 103050,608222) PREDICTED: adenylos (480 aa) initn: 2643 init1: 2643 opt: 2645 Z-score: 3382.7 bits: 635.1 E(85289): 1.1e-181 Smith-Waterman score: 2645; 96.2% identity (97.4% similar) in 418 aa overlap (1-418:1-415) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK ::::::::::::::::::::::::::::::::::::: .:.. : . ::.: XP_011 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQE 370 380 390 400 410 pF1KB3 AELCL XP_011 GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMK 420 430 440 450 460 470 >>NP_000017 (OMIM: 103050,608222) adenylosuccinate lyase (484 aa) initn: 2643 init1: 2643 opt: 2645 Z-score: 3382.6 bits: 635.1 E(85289): 1.1e-181 Smith-Waterman score: 2645; 96.2% identity (97.4% similar) in 418 aa overlap (1-418:1-415) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK ::::::::::::::::::::::::::::::::::::: .:.. : . ::.: NP_000 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQE 370 380 390 400 410 pF1KB3 AELCL NP_000 GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMK 420 430 440 450 460 470 >-- initn: 218 init1: 194 opt: 194 Z-score: 245.7 bits: 54.7 E(85289): 6e-07 Smith-Waterman score: 194; 96.8% identity (100.0% similar) in 31 aa overlap (395-425:454-484) 370 380 390 400 410 420 pF1KB3 YPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELC :.:::::::::::::::::::::::::::: NP_000 IERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 430 440 450 460 470 480 pF1KB3 L : NP_000 L >>XP_011528279 (OMIM: 103050,608222) PREDICTED: adenylos (526 aa) initn: 2777 init1: 2643 opt: 2645 Z-score: 3382.1 bits: 635.2 E(85289): 1.2e-181 Smith-Waterman score: 2645; 96.2% identity (97.4% similar) in 418 aa overlap (1-418:1-415) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK ::::::::::::::::::::::::::::::::::::: .:.. : . ::.: XP_011 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQE 370 380 390 400 410 pF1KB3 AELCL XP_011 GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMK 420 430 440 450 460 470 >>NP_001304852 (OMIM: 103050,608222) adenylosuccinate ly (420 aa) initn: 2190 init1: 2190 opt: 2192 Z-score: 2803.8 bits: 527.8 E(85289): 2e-149 Smith-Waterman score: 2192; 95.5% identity (96.9% similar) in 354 aa overlap (65-418:1-351) 40 50 60 70 80 90 pF1KB3 KFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHT :::::::::::::::::::::::::::::: NP_001 MKSNLENIDFKMAAEEEKRLRHDVMAHVHT 10 20 30 100 110 120 130 140 150 pF1KB3 FGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPT 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 LGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 DDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLAN 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 LKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 ANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGG 280 290 300 310 320 330 400 410 420 pF1KB3 SRQVQRFLEEEVYPLLKPYESVMKVKAELCL ::: .:.. : . ::.: NP_001 SRQD---CHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTG 340 350 360 370 380 >-- initn: 218 init1: 194 opt: 194 Z-score: 246.6 bits: 54.7 E(85289): 5.4e-07 Smith-Waterman score: 194; 96.8% identity (100.0% similar) in 31 aa overlap (395-425:390-420) 370 380 390 400 410 420 pF1KB3 YPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELC :.:::::::::::::::::::::::::::: NP_001 IERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 360 370 380 390 400 410 pF1KB3 L : NP_001 L 420 >>XP_016884126 (OMIM: 103050,608222) PREDICTED: adenylos (469 aa) initn: 2538 init1: 1716 opt: 1718 Z-score: 2196.4 bits: 415.6 E(85289): 1.3e-115 Smith-Waterman score: 2514; 92.6% identity (93.8% similar) in 418 aa overlap (1-418:1-400) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNT- 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::: XP_016 --------------LARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK ::::::::::::::::::::::::::::::::::::: .:.. : . ::.: XP_016 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQE 350 360 370 380 390 400 pF1KB3 AELCL XP_016 GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMK 410 420 430 440 450 460 >-- initn: 218 init1: 194 opt: 194 Z-score: 245.9 bits: 54.7 E(85289): 5.9e-07 Smith-Waterman score: 194; 96.8% identity (100.0% similar) in 31 aa overlap (395-425:439-469) 370 380 390 400 410 420 pF1KB3 YPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELC :.:::::::::::::::::::::::::::: XP_016 IERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 410 420 430 440 450 460 pF1KB3 L : XP_016 L >>XP_016884125 (OMIM: 103050,608222) PREDICTED: adenylos (511 aa) initn: 2672 init1: 1716 opt: 1718 Z-score: 2195.9 bits: 415.6 E(85289): 1.4e-115 Smith-Waterman score: 2514; 92.6% identity (93.8% similar) in 418 aa overlap (1-418:1-400) 10 20 30 40 50 60 pF1KB3 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNT- 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC :::::::::::::::::::::::::::::::::::::::::::::: XP_016 --------------LARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK ::::::::::::::::::::::::::::::::::::: .:.. : . ::.: XP_016 GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQE 350 360 370 380 390 400 pF1KB3 AELCL XP_016 GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMK 410 420 430 440 450 460 >>XP_016884128 (OMIM: 103050,608222) PREDICTED: adenylos (329 aa) initn: 1546 init1: 1546 opt: 1548 Z-score: 1981.1 bits: 375.2 E(85289): 1.3e-103 Smith-Waterman score: 1548; 93.8% identity (95.7% similar) in 257 aa overlap (162-418:7-260) 140 150 160 170 180 190 pF1KB3 LPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRD :::::::::::::::::::::::::::::: XP_016 MLETILPAQLTTVGKRCCLWIQDLCMDLQNLKRVRD 10 20 30 200 210 220 230 240 250 pF1KB3 DLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB3 LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHL 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB3 MTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIER 160 170 180 190 200 210 380 390 400 410 420 pF1KB3 RIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELCL :::::::::::::::::::::::::: .:.. : . ::.: XP_016 RIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQEGGDNDLIERIQ 220 230 240 250 260 270 XP_016 VDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 280 290 300 310 320 >-- initn: 218 init1: 194 opt: 194 Z-score: 248.2 bits: 54.6 E(85289): 4.4e-07 Smith-Waterman score: 194; 96.8% identity (100.0% similar) in 31 aa overlap (395-425:299-329) 370 380 390 400 410 420 pF1KB3 YPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELC :.:::::::::::::::::::::::::::: XP_016 IERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 270 280 290 300 310 320 pF1KB3 L : XP_016 L >>XP_016884127 (OMIM: 103050,608222) PREDICTED: adenylos (371 aa) initn: 1680 init1: 1546 opt: 1548 Z-score: 1980.4 bits: 375.3 E(85289): 1.4e-103 Smith-Waterman score: 1548; 93.8% identity (95.7% similar) in 257 aa overlap (162-418:7-260) 140 150 160 170 180 190 pF1KB3 LPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRD :::::::::::::::::::::::::::::: XP_016 MLETILPAQLTTVGKRCCLWIQDLCMDLQNLKRVRD 10 20 30 200 210 220 230 240 250 pF1KB3 DLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB3 LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHL 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB3 MTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIER 160 170 180 190 200 210 380 390 400 410 420 pF1KB3 RIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELCL :::::::::::::::::::::::::: .:.. : . ::.: XP_016 RIRQELPFMATENIIMAMVKAGGSRQD---CHEKIRVLSQQAASVVKQEGGDNDLIERIQ 220 230 240 250 260 270 XP_016 VDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKCKQVPLDKNVV 280 290 300 310 320 330 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:23:29 2016 done: Fri Nov 4 02:23:30 2016 Total Scan time: 7.280 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]