FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3428, 423 aa 1>>>pF1KB3428 423 - 423 aa - 423 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5565+/-0.000396; mu= 16.4347+/- 0.025 mean_var=79.5504+/-16.082, 0's: 0 Z-trim(112.8): 18 B-trim: 161 in 1/53 Lambda= 0.143798 statistics sampled from 21794 (21803) to 21794 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.256), width: 16 Scan time: 8.560 The best scores are: opt bits E(85289) NP_002426 (OMIM: 154550,602579) mannose-6-phosphat ( 423) 2807 592.2 8.2e-169 XP_011519894 (OMIM: 154550,602579) PREDICTED: mann ( 419) 2773 585.1 1.1e-166 NP_001317301 (OMIM: 154550,602579) mannose-6-phosp ( 403) 2661 561.9 1e-159 NP_001276085 (OMIM: 154550,602579) mannose-6-phosp ( 373) 2467 521.6 1.3e-147 NP_001276084 (OMIM: 154550,602579) mannose-6-phosp ( 287) 1871 397.9 1.7e-110 XP_016877696 (OMIM: 154550,602579) PREDICTED: mann ( 283) 1837 390.9 2.2e-108 XP_016877697 (OMIM: 154550,602579) PREDICTED: mann ( 267) 1725 367.6 2.1e-101 XP_016877698 (OMIM: 154550,602579) PREDICTED: mann ( 237) 1531 327.3 2.5e-89 NP_001276086 (OMIM: 154550,602579) mannose-6-phosp ( 362) 1327 285.1 1.9e-76 >>NP_002426 (OMIM: 154550,602579) mannose-6-phosphate is (423 aa) initn: 2807 init1: 2807 opt: 2807 Z-score: 3151.7 bits: 592.2 E(85289): 8.2e-169 Smith-Waterman score: 2807; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 370 380 390 400 410 420 pF1KB3 CLL ::: NP_002 CLL >>XP_011519894 (OMIM: 154550,602579) PREDICTED: mannose- (419 aa) initn: 2773 init1: 2773 opt: 2773 Z-score: 3113.7 bits: 585.1 E(85289): 1.1e-166 Smith-Waterman score: 2773; 100.0% identity (100.0% similar) in 418 aa overlap (6-423:2-419) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 360 370 380 390 400 410 pF1KB3 CLL ::: XP_011 CLL >>NP_001317301 (OMIM: 154550,602579) mannose-6-phosphate (403 aa) initn: 2661 init1: 2661 opt: 2661 Z-score: 2988.3 bits: 561.9 E(85289): 1e-159 Smith-Waterman score: 2661; 100.0% identity (100.0% similar) in 403 aa overlap (21-423:1-403) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK :::::::::::::::::::::::::::::::::::::::: NP_001 MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 350 360 370 380 390 400 pF1KB3 CLL ::: NP_001 CLL >>NP_001276085 (OMIM: 154550,602579) mannose-6-phosphate (373 aa) initn: 2467 init1: 2467 opt: 2467 Z-score: 2771.3 bits: 521.6 E(85289): 1.3e-147 Smith-Waterman score: 2467; 100.0% identity (100.0% similar) in 373 aa overlap (51-423:1-373) 30 40 50 60 70 80 pF1KB3 MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQD :::::::::::::::::::::::::::::: NP_001 MGTHPRGDAKILDNRISQKTLSQWIAENQD 10 20 30 90 100 110 120 130 140 pF1KB3 SLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 ALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSH 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 LMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 TLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSK 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB3 DRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIAS 280 290 300 310 320 330 390 400 410 420 pF1KB3 TPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL ::::::::::::::::::::::::::::::::::::::::::: NP_001 TPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL 340 350 360 370 >>NP_001276084 (OMIM: 154550,602579) mannose-6-phosphate (287 aa) initn: 1869 init1: 1869 opt: 1871 Z-score: 2104.7 bits: 397.9 E(85289): 1.7e-110 Smith-Waterman score: 1871; 98.6% identity (98.6% similar) in 286 aa overlap (1-286:1-286) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP ::::::::::::::::::::::::::::::::::::::::: : NP_001 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGGPWLCH 250 260 270 280 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK >>XP_016877696 (OMIM: 154550,602579) PREDICTED: mannose- (283 aa) initn: 1835 init1: 1835 opt: 1837 Z-score: 2066.7 bits: 390.9 E(85289): 2.2e-108 Smith-Waterman score: 1837; 98.6% identity (98.6% similar) in 281 aa overlap (6-286:2-282) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP ::::::::::::::::::::::::::::::::::::::::: : XP_016 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGGPWLCH 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK >>XP_016877697 (OMIM: 154550,602579) PREDICTED: mannose- (267 aa) initn: 1723 init1: 1723 opt: 1725 Z-score: 1941.5 bits: 367.6 E(85289): 2.1e-101 Smith-Waterman score: 1725; 98.5% identity (98.5% similar) in 266 aa overlap (21-286:1-266) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK :::::::::::::::::::::::::::::::::::::::: XP_016 MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP ::::::::::::::::::::::::::::::::::::::::: : XP_016 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGGPWLCH 230 240 250 260 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK >>XP_016877698 (OMIM: 154550,602579) PREDICTED: mannose- (237 aa) initn: 1529 init1: 1529 opt: 1531 Z-score: 1724.7 bits: 327.3 E(85289): 2.5e-89 Smith-Waterman score: 1531; 98.3% identity (98.3% similar) in 236 aa overlap (51-286:1-236) 30 40 50 60 70 80 pF1KB3 MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQD :::::::::::::::::::::::::::::: XP_016 MGTHPRGDAKILDNRISQKTLSQWIAENQD 10 20 30 90 100 110 120 130 140 pF1KB3 SLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 ALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSH 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 LMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 TLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSK ::::::::::::::::::::: : XP_016 TLKPGEAMFLEANVPHAYLKGGPWLCH 220 230 >>NP_001276086 (OMIM: 154550,602579) mannose-6-phosphate (362 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1493.3 bits: 285.1 E(85289): 1.9e-76 Smith-Waterman score: 2287; 85.3% identity (85.6% similar) in 423 aa overlap (1-423:1-362) 10 20 30 40 50 60 pF1KB3 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK :::::::::::::::::::::::::::::::::::::::::: NP_001 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLK------------------ 130 140 150 160 190 200 210 220 230 240 pF1KB3 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ .:::::::::::::::: NP_001 -------------------------------------------TAAGNNMEDIFGELLLQ 170 250 260 270 280 290 300 pF1KB3 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB3 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 240 250 260 270 280 290 370 380 390 400 410 420 pF1KB3 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 300 310 320 330 340 350 pF1KB3 CLL ::: NP_001 CLL 360 423 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:59:53 2016 done: Sat Nov 5 04:59:54 2016 Total Scan time: 8.560 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]