FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3431, 225 aa 1>>>pF1KB3431 225 - 225 aa - 225 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1051+/-0.000295; mu= 11.2223+/- 0.019 mean_var=97.6567+/-19.832, 0's: 0 Z-trim(119.7): 30 B-trim: 286 in 1/53 Lambda= 0.129785 statistics sampled from 34027 (34057) to 34027 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.399), width: 16 Scan time: 7.190 The best scores are: opt bits E(85289) NP_001032752 (OMIM: 600655) elongation factor 1-be ( 225) 1483 287.2 1.5e-77 NP_001950 (OMIM: 600655) elongation factor 1-beta ( 225) 1483 287.2 1.5e-77 NP_066944 (OMIM: 600655) elongation factor 1-beta ( 225) 1483 287.2 1.5e-77 NP_001317575 (OMIM: 130592) elongation factor 1-de ( 257) 736 147.3 2.2e-35 NP_001304672 (OMIM: 130592) elongation factor 1-de ( 257) 736 147.3 2.2e-35 NP_001123528 (OMIM: 130592) elongation factor 1-de ( 257) 736 147.3 2.2e-35 NP_001182132 (OMIM: 130592) elongation factor 1-de ( 262) 736 147.3 2.2e-35 NP_001276879 (OMIM: 130592) elongation factor 1-de ( 281) 736 147.4 2.3e-35 XP_006716588 (OMIM: 130592) PREDICTED: elongation ( 281) 736 147.4 2.3e-35 NP_001951 (OMIM: 130592) elongation factor 1-delta ( 281) 736 147.4 2.3e-35 NP_001123529 (OMIM: 130592) elongation factor 1-de ( 281) 736 147.4 2.3e-35 NP_001123527 (OMIM: 130592) elongation factor 1-de ( 281) 736 147.4 2.3e-35 XP_016868661 (OMIM: 130592) PREDICTED: elongation ( 623) 736 147.6 4.4e-35 XP_016868660 (OMIM: 130592) PREDICTED: elongation ( 646) 736 147.6 4.5e-35 XP_005250880 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 XP_016868659 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 XP_006716585 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 NP_115754 (OMIM: 130592) elongation factor 1-delta ( 647) 736 147.6 4.5e-35 XP_006716586 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 NP_001123525 (OMIM: 130592) elongation factor 1-de ( 647) 736 147.6 4.5e-35 XP_011515207 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 XP_006716587 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 XP_011515208 (OMIM: 130592) PREDICTED: elongation ( 647) 736 147.6 4.5e-35 XP_006716583 (OMIM: 130592) PREDICTED: elongation ( 664) 736 147.6 4.6e-35 XP_006716582 (OMIM: 130592) PREDICTED: elongation ( 687) 736 147.6 4.8e-35 XP_005250877 (OMIM: 130592) PREDICTED: elongation ( 688) 736 147.6 4.8e-35 XP_016868657 (OMIM: 130592) PREDICTED: elongation ( 688) 736 147.6 4.8e-35 XP_016868658 (OMIM: 130592) PREDICTED: elongation ( 688) 736 147.6 4.8e-35 >>NP_001032752 (OMIM: 600655) elongation factor 1-beta [ (225 aa) initn: 1483 init1: 1483 opt: 1483 Z-score: 1513.0 bits: 287.2 E(85289): 1.5e-77 Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KB3 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV 130 140 150 160 170 180 190 200 210 220 pF1KB3 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI ::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI 190 200 210 220 >>NP_001950 (OMIM: 600655) elongation factor 1-beta [Hom (225 aa) initn: 1483 init1: 1483 opt: 1483 Z-score: 1513.0 bits: 287.2 E(85289): 1.5e-77 Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KB3 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV 130 140 150 160 170 180 190 200 210 220 pF1KB3 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI ::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI 190 200 210 220 >>NP_066944 (OMIM: 600655) elongation factor 1-beta [Hom (225 aa) initn: 1483 init1: 1483 opt: 1483 Z-score: 1513.0 bits: 287.2 E(85289): 1.5e-77 Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KB3 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 ERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPV 130 140 150 160 170 180 190 200 210 220 pF1KB3 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI ::::::::::::::::::::::::::::::::::::::::::::: NP_066 GYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI 190 200 210 220 >>NP_001317575 (OMIM: 130592) elongation factor 1-delta (257 aa) initn: 726 init1: 726 opt: 736 Z-score: 756.3 bits: 147.3 E(85289): 2.2e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:93-257) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 70 80 90 100 110 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 180 190 200 210 220 230 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 240 250 >>NP_001304672 (OMIM: 130592) elongation factor 1-delta (257 aa) initn: 726 init1: 726 opt: 736 Z-score: 756.3 bits: 147.3 E(85289): 2.2e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:93-257) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 70 80 90 100 110 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 180 190 200 210 220 230 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 240 250 >>NP_001123528 (OMIM: 130592) elongation factor 1-delta (257 aa) initn: 726 init1: 726 opt: 736 Z-score: 756.3 bits: 147.3 E(85289): 2.2e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:93-257) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 70 80 90 100 110 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 180 190 200 210 220 230 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 240 250 >>NP_001182132 (OMIM: 130592) elongation factor 1-delta (262 aa) initn: 726 init1: 726 opt: 736 Z-score: 756.2 bits: 147.3 E(85289): 2.2e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:98-262) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 GASSGTSGDHVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 190 200 210 220 230 240 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 250 260 >>NP_001276879 (OMIM: 130592) elongation factor 1-delta (281 aa) initn: 726 init1: 726 opt: 736 Z-score: 755.7 bits: 147.4 E(85289): 2.3e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:117-281) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 210 220 230 240 250 260 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 270 280 >>XP_006716588 (OMIM: 130592) PREDICTED: elongation fact (281 aa) initn: 726 init1: 726 opt: 736 Z-score: 755.7 bits: 147.4 E(85289): 2.3e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:117-281) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . XP_006 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: XP_006 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. XP_006 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 210 220 230 240 250 260 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: XP_006 ITKFEEHVQSVDIAAFNKI 270 280 >>NP_001951 (OMIM: 130592) elongation factor 1-delta iso (281 aa) initn: 726 init1: 726 opt: 736 Z-score: 755.7 bits: 147.4 E(85289): 2.3e-35 Smith-Waterman score: 736; 69.8% identity (85.2% similar) in 169 aa overlap (60-225:117-281) 30 40 50 60 70 80 pF1KB3 PSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPA-DVEDTT :: ..:. : .... .: .:: . NP_001 LEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHV----SPMRQVEPPA 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB3 GSGATDSKDD--DDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDV . :: ..:: :::::::::.:::..:: .:::::: :: :::::::::::::::::: NP_001 KKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDV 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB3 KPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQ ::::::::::.:: :::::: ::::::.::::::::::.::::::::::::::::.:::. NP_001 KPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEE 210 220 230 240 250 260 210 220 pF1KB3 ITAFEDYVQSMDVAAFNKI :: ::..:::.:.:::::: NP_001 ITKFEEHVQSVDIAAFNKI 270 280 225 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:01:23 2016 done: Sat Nov 5 05:01:24 2016 Total Scan time: 7.190 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]