FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3434, 323 aa 1>>>pF1KB3434 323 - 323 aa - 323 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6384+/-0.000274; mu= 12.0424+/- 0.017 mean_var=126.7481+/-24.515, 0's: 0 Z-trim(123.0): 19 B-trim: 0 in 0/59 Lambda= 0.113921 statistics sampled from 41988 (42009) to 41988 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.493), width: 16 Scan time: 9.250 The best scores are: opt bits E(85289) NP_002966 (OMIM: 604713) C-type lectin domain fami ( 323) 2259 381.5 1.3e-105 NP_005743 (OMIM: 613588) C-type lectin domain fami ( 206) 223 46.7 4.8e-05 NP_001295323 (OMIM: 187520) tetranectin isoform 2 ( 160) 206 43.9 0.00028 NP_001231684 (OMIM: 613588) C-type lectin domain f ( 145) 205 43.7 0.00029 XP_016862605 (OMIM: 187520) PREDICTED: tetranectin ( 169) 206 43.9 0.00029 NP_003269 (OMIM: 187520) tetranectin isoform 1prec ( 202) 206 43.9 0.00033 XP_016862606 (OMIM: 187520) PREDICTED: tetranectin ( 209) 206 43.9 0.00034 >>NP_002966 (OMIM: 604713) C-type lectin domain family 1 (323 aa) initn: 2259 init1: 2259 opt: 2259 Z-score: 2017.3 bits: 381.5 E(85289): 1.3e-105 Smith-Waterman score: 2259; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KB3 MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RGDENPAGTVEGKEDWEMEEDQGEEEEEEATPTPSSGPSPSPTPEDIVTYILGRLAGLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RGDENPAGTVEGKEDWEMEEDQGEEEEEEATPTPSSGPSPSPTPEDIVTYILGRLAGLDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQA 250 260 270 280 290 300 310 320 pF1KB3 SDDGSWWDHDCQRRLYYVCEFPF ::::::::::::::::::::::: NP_002 SDDGSWWDHDCQRRLYYVCEFPF 310 320 >>NP_005743 (OMIM: 613588) C-type lectin domain family 3 (206 aa) initn: 305 init1: 124 opt: 223 Z-score: 211.5 bits: 46.7 E(85289): 4.8e-05 Smith-Waterman score: 299; 31.1% identity (55.0% similar) in 180 aa overlap (144-321:44-202) 120 130 140 150 160 170 pF1KB3 RLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGR :..:. :: . .. : .. : .: NP_005 GLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGDLKTQIEKLW-TEVNALKEIQA 20 30 40 50 60 70 180 190 200 210 220 230 pF1KB3 LEG-CLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALA :. ::.: .. .::.: :. .. :. : ..:: :. : . ....:: : . .: NP_005 LQTVCLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLP 80 90 100 110 120 130 240 250 260 270 280 290 pF1KB3 PYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGT : :::..: .:: .. :: .::. : :. ::::: NP_005 GVN-DFWLGINDMVTEGKFVDVNGIAISFLNWDRA-------------------QPNGGK 140 150 160 170 300 310 320 pF1KB3 LENCVA-QASDDGSWWDHDCQRRLYYVCEFPF :::: . : .:.: :. :. :.::: NP_005 RENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ 180 190 200 >>NP_001295323 (OMIM: 187520) tetranectin isoform 2 [Hom (160 aa) initn: 246 init1: 130 opt: 206 Z-score: 197.9 bits: 43.9 E(85289): 0.00028 Smith-Waterman score: 286; 32.9% identity (60.3% similar) in 146 aa overlap (177-321:29-157) 150 160 170 180 190 200 pF1KB3 RNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTA :::: .. :::: . .. :. : . NP_001 MFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCIS 10 20 30 40 50 210 220 230 240 250 260 pF1KB3 RGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHR :::.:. : .. .:: .::: ... . .:::..: ::: .. .: :... :. NP_001 RGGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLNDMAAEGTWVDMTGARIAYKNWE- 60 70 80 90 100 110 270 280 290 300 310 320 pF1KB3 SPRPELGAQPSASPHPLSPDQPNGGTLENC-VAQASDDGSWWDHDCQRRLYYVCEFPF :. ::: .:: ::: : ... .:.:.:. :. .: :.:.: NP_001 ---TEITAQP------------DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 120 130 140 150 160 >>NP_001231684 (OMIM: 613588) C-type lectin domain famil (145 aa) initn: 297 init1: 120 opt: 205 Z-score: 197.6 bits: 43.7 E(85289): 0.00029 Smith-Waterman score: 281; 32.5% identity (55.2% similar) in 154 aa overlap (169-321:8-141) 140 150 160 170 180 190 pF1KB3 LTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQA :. . : ::.: .. .::.: :. .. NP_001 MILILQMRKMRHKEVCLRGTKVHKKCYLASEGLKHFH 10 20 30 200 210 220 230 240 250 pF1KB3 AAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQR :. : ..:: :. : . ....:: : . .: : :::..: .:: .. :: NP_001 EANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVN-DFWLGINDMVTEGKFVDVNGIA 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB3 VSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVA-QASDDGSWWDHDCQRRLYY .::. : :. ::::: :::: . : .:.: :. :. : NP_001 ISFLNWDRA-------------------QPNGGKRENCVLFSQSAQGKWSDEACRSSKRY 100 110 120 130 320 pF1KB3 VCEFPF .::: NP_001 ICEFTIPQ 140 >>XP_016862605 (OMIM: 187520) PREDICTED: tetranectin iso (169 aa) initn: 246 init1: 130 opt: 206 Z-score: 197.6 bits: 43.9 E(85289): 0.00029 Smith-Waterman score: 286; 32.9% identity (60.3% similar) in 146 aa overlap (177-321:38-166) 150 160 170 180 190 200 pF1KB3 RNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTA :::: .. :::: . .. :. : . XP_016 LLLCLFSLLTQVTTEPPTQKPKKIVNAKKVCLKGTKVHMKCFLAFTQTKTFHEASEDCIS 10 20 30 40 50 60 210 220 230 240 250 260 pF1KB3 RGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHR :::.:. : .. .:: .::: ... . .:::..: ::: .. .: :... :. XP_016 RGGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLNDMAAEGTWVDMTGARIAYKNWE- 70 80 90 100 110 120 270 280 290 300 310 320 pF1KB3 SPRPELGAQPSASPHPLSPDQPNGGTLENC-VAQASDDGSWWDHDCQRRLYYVCEFPF :. ::: .:: ::: : ... .:.:.:. :. .: :.:.: XP_016 ---TEITAQP------------DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 130 140 150 160 >>NP_003269 (OMIM: 187520) tetranectin isoform 1precurso (202 aa) initn: 246 init1: 130 opt: 206 Z-score: 196.5 bits: 43.9 E(85289): 0.00033 Smith-Waterman score: 288; 29.5% identity (57.5% similar) in 193 aa overlap (140-321:25-199) 110 120 130 140 150 160 pF1KB3 YILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAE- :: ... :: :. .. . ..: ..: . NP_003 MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNT-KMFEELKSRLDT 10 20 30 40 50 170 180 190 200 210 pF1KB3 --------REHGRLEG-CLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQ .:. :. :::: .. :::: . .. :. : .:::.:. : .. NP_003 LAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSE 60 70 80 90 100 110 220 230 240 250 260 270 pF1KB3 MEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSAS .:: .::: ... .:::..: ::: .. .: :... :. :. ::: NP_003 NDALYEYLRQSVGNEA-EIWLGLNDMAAEGTWVDMTGARIAYKNWE----TEITAQP--- 120 130 140 150 160 280 290 300 310 320 pF1KB3 PHPLSPDQPNGGTLENC-VAQASDDGSWWDHDCQRRLYYVCEFPF .:: ::: : ... .:.:.:. :. .: :.:.: NP_003 ---------DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 170 180 190 200 >>XP_016862606 (OMIM: 187520) PREDICTED: tetranectin iso (209 aa) initn: 288 init1: 130 opt: 206 Z-score: 196.3 bits: 43.9 E(85289): 0.00034 Smith-Waterman score: 286; 32.9% identity (60.3% similar) in 146 aa overlap (177-321:78-206) 150 160 170 180 190 200 pF1KB3 RNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTA :::: .. :::: . .. :. : . XP_016 PLSPTLPALRRTDPAKGTWQALEACLGCLVCLKGTKVHMKCFLAFTQTKTFHEASEDCIS 50 60 70 80 90 100 210 220 230 240 250 260 pF1KB3 RGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHR :::.:. : .. .:: .::: ... . .:::..: ::: .. .: :... :. XP_016 RGGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLNDMAAEGTWVDMTGARIAYKNWE- 110 120 130 140 150 160 270 280 290 300 310 320 pF1KB3 SPRPELGAQPSASPHPLSPDQPNGGTLENC-VAQASDDGSWWDHDCQRRLYYVCEFPF :. ::: .:: ::: : ... .:.:.:. :. .: :.:.: XP_016 ---TEITAQP------------DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 170 180 190 200 323 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:07:00 2016 done: Fri Nov 4 21:07:01 2016 Total Scan time: 9.250 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]