FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3445, 202 aa 1>>>pF1KB3445 202 - 202 aa - 202 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9079+/-0.000705; mu= 15.3748+/- 0.042 mean_var=60.2025+/-11.929, 0's: 0 Z-trim(109.5): 17 B-trim: 0 in 0/52 Lambda= 0.165298 statistics sampled from 10930 (10946) to 10930 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.336), width: 16 Scan time: 1.980 The best scores are: opt bits E(32554) CCDS46709.1 APOBEC3D gene_id:140564|Hs108|chr22 ( 386) 977 241.0 7.1e-64 CCDS33648.1 APOBEC3F gene_id:200316|Hs108|chr22 ( 373) 861 213.3 1.5e-55 CCDS13983.1 APOBEC3C gene_id:27350|Hs108|chr22 ( 190) 810 201.0 3.9e-52 CCDS58807.1 APOBEC3B gene_id:9582|Hs108|chr22 ( 357) 518 131.5 6e-31 CCDS13982.1 APOBEC3B gene_id:9582|Hs108|chr22 ( 382) 518 131.5 6.3e-31 CCDS13984.1 APOBEC3G gene_id:60489|Hs108|chr22 ( 384) 435 111.8 5.8e-25 CCDS41747.1 AICDA gene_id:57379|Hs108|chr12 ( 198) 384 99.4 1.5e-21 CCDS13981.1 APOBEC3A gene_id:200315|Hs108|chr22 ( 199) 378 98.0 4.2e-21 CCDS13985.1 APOBEC3H gene_id:164668|Hs108|chr22 ( 183) 342 89.4 1.5e-18 CCDS54531.1 APOBEC3H gene_id:164668|Hs108|chr22 ( 182) 338 88.4 2.9e-18 CCDS54530.1 APOBEC3H gene_id:164668|Hs108|chr22 ( 200) 338 88.4 3.1e-18 CCDS4848.1 APOBEC2 gene_id:10930|Hs108|chr6 ( 224) 285 75.8 2.2e-14 CCDS8579.1 APOBEC1 gene_id:339|Hs108|chr12 ( 236) 280 74.7 5.2e-14 CCDS81662.1 AICDA gene_id:57379|Hs108|chr12 ( 188) 262 70.3 8.5e-13 CCDS54532.1 APOBEC3H gene_id:164668|Hs108|chr22 ( 154) 247 66.7 8.6e-12 >>CCDS46709.1 APOBEC3D gene_id:140564|Hs108|chr22 (386 aa) initn: 977 init1: 977 opt: 977 Z-score: 1260.2 bits: 241.0 E(32554): 7.1e-64 Smith-Waterman score: 1080; 77.3% identity (84.8% similar) in 198 aa overlap (5-202:201-386) 10 20 30 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTW .::::: :: :: .:.: ::. .: CCDS46 NFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESW 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB3 LCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSP ::. ... . .: .. ::::. .:::::::::::::::::::::::: CCDS46 LCFTMEVTKHHSAVFRKRGVFRN------------QVDPETHCHAERCFLSWFCDDILSP 240 250 260 270 100 110 120 130 140 150 pF1KB3 NTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEG 280 290 300 310 320 330 160 170 180 190 200 pF1KB3 ASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ 340 350 360 370 380 >-- initn: 949 init1: 949 opt: 949 Z-score: 1224.1 bits: 234.3 E(32554): 7.3e-62 Smith-Waterman score: 949; 66.0% identity (81.5% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFL ::::::::::: . . ::: ::::::: . : : ...::..::.:: :. .:..:: CCDS46 PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPF :.: ::.::: .::: :. : :.. : : . :: :::: :.::. ::.::: .. .:: CCDS46 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 130 140 150 160 170 180 190 200 pF1KB3 KPWKGLQTNFRLLKRRLREILQ :: .. :. :.: :.:: CCDS46 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH 190 200 210 220 230 240 >>CCDS33648.1 APOBEC3F gene_id:200316|Hs108|chr22 (373 aa) initn: 1518 init1: 847 opt: 861 Z-score: 1110.9 bits: 213.3 E(32554): 1.5e-55 Smith-Waterman score: 985; 70.2% identity (81.3% similar) in 198 aa overlap (5-202:188-373) 10 20 30 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTW .::::: :: :: .:.: :::. .: CCDS33 NFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESW 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB3 LCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSP ::. ... . .: . : ::::. .:::::::::::::::::::::::: CCDS33 LCFTMEVVKHHSPVSWKRGVFRN------------QVDPETHCHAERCFLSWFCDDILSP 220 230 240 250 260 100 110 120 130 140 150 pF1KB3 NTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEG ::::::::::::::::::::::::::::::::::::::::: ::::::::::: :::::: CCDS33 NTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEG 270 280 290 300 310 320 160 170 180 190 200 pF1KB3 ASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ :::.::::::: ::.::::.:::::::::::. :: .: .:.:::. CCDS33 ASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 330 340 350 360 370 >-- initn: 701 init1: 524 opt: 708 Z-score: 913.7 bits: 176.8 E(32554): 1.4e-44 Smith-Waterman score: 708; 51.5% identity (72.5% similar) in 200 aa overlap (1-200:1-187) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL :.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::: : CCDS33 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFL . :: : ::: ::::::: . : ...::..::.:::.:....:::: CCDS33 SQ----------PE-H-HAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 ARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPF :.: ::.::: .::: :.:. ::...:: ::: :: :::: ..:. ::.:::::. .:: CCDS33 AEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPF 110 120 130 140 150 160 190 200 pF1KB3 KPWKGLQTNFRLLKRRLREILQ :: .. :. .:.: :.:: CCDS33 MPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKH 170 180 190 200 210 220 >>CCDS13983.1 APOBEC3C gene_id:27350|Hs108|chr22 (190 aa) initn: 799 init1: 799 opt: 810 Z-score: 1049.4 bits: 201.0 E(32554): 3.9e-52 Smith-Waterman score: 952; 70.4% identity (80.3% similar) in 203 aa overlap (1-202:1-190) 10 20 30 40 50 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVK-IKRGRSNLLWDTGVFRGPV :::::::::. :: ::: .:.: :. ::::. :. ::: :: . : :::::. CCDS13 MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKR-RSVVSWKTGVFRN-- 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 LPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEF .:: :::::::::::::::::::::::.:.:::::::::::.:::::::: CCDS13 ----------QVDSETHCHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEF 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 LARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEP :::::::::::::::: :: ::::: ::::::..:.:: :.:: ::.::::.:.:: CCDS13 LARHSNVNLTIFTARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEP 110 120 130 140 150 160 180 190 200 pF1KB3 FKPWKGLQTNFRLLKRRLREILQ :::::::.:::::::::::: :: CCDS13 FKPWKGLKTNFRLLKRRLRESLQ 170 180 190 >>CCDS58807.1 APOBEC3B gene_id:9582|Hs108|chr22 (357 aa) initn: 921 init1: 515 opt: 518 Z-score: 669.1 bits: 131.5 E(32554): 6e-31 Smith-Waterman score: 899; 61.4% identity (78.7% similar) in 202 aa overlap (1-202:1-190) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS58 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFL : : ::: ::::::: . : ...::..::.:::.:....:::: CCDS58 FKPQY------------HAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL 70 80 90 100 130 140 150 160 170 180 pF1KB3 ARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPF ..: ::.::: .::: :.:. ::...:: ::: :: : :: :..:. ::.::::.. . : CCDS58 SEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVTIMDYEEFAYCWENFVYNEGQQF 110 120 130 140 150 160 190 200 pF1KB3 KPWKGLQTNFRLLKRRLREILQ :: .. :. .:.: :.:::. CCDS58 MPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTW 170 180 190 200 210 220 >-- initn: 402 init1: 178 opt: 361 Z-score: 466.8 bits: 94.1 E(32554): 1.1e-19 Smith-Waterman score: 390; 39.9% identity (61.1% similar) in 193 aa overlap (12-202:193-353) 10 20 30 40 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKI : ::: ::.:.:.. : :.:::::. CCDS58 NEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVE- 170 180 190 200 210 220 50 60 70 80 90 100 pF1KB3 KRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVT : :.:.. :: ...: ....:.. :.: :.:: CCDS58 -R------LDNGTW---VL---MDQH----------------MGFLCNE-LDPAQIYRVT 230 240 250 110 120 130 140 150 pF1KB3 WYTSWSPCPE--CAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKI :. ::::: ::::: :: ....: : ::.::. : .: :.:.: : . ::.:.: CCDS58 WFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSI 260 270 280 290 300 310 160 170 180 190 200 pF1KB3 MGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ : : .: :: .::: . ::.:: ::. . . :. ::: ::: CCDS58 MTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN 320 330 340 350 >>CCDS13982.1 APOBEC3B gene_id:9582|Hs108|chr22 (382 aa) initn: 921 init1: 515 opt: 518 Z-score: 668.7 bits: 131.5 E(32554): 6.3e-31 Smith-Waterman score: 899; 61.4% identity (78.7% similar) in 202 aa overlap (1-202:1-190) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS13 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFL : : ::: ::::::: . : ...::..::.:::.:....:::: CCDS13 FKPQY------------HAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL 70 80 90 100 130 140 150 160 170 180 pF1KB3 ARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPF ..: ::.::: .::: :.:. ::...:: ::: :: : :: :..:. ::.::::.. . : CCDS13 SEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVTIMDYEEFAYCWENFVYNEGQQF 110 120 130 140 150 160 190 200 pF1KB3 KPWKGLQTNFRLLKRRLREILQ :: .. :. .:.: :.:::. CCDS13 MPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTW 170 180 190 200 210 220 >-- initn: 425 init1: 178 opt: 413 Z-score: 533.4 bits: 106.5 E(32554): 2.2e-23 Smith-Waterman score: 413; 40.9% identity (60.6% similar) in 198 aa overlap (12-202:193-378) 10 20 30 40 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKI : ::: ::.:.:.. : :.:::::. CCDS13 NEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVE- 170 180 190 200 210 220 50 60 70 80 90 pF1KB3 KRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHC-----HAERCFLSWFCDDILSPNT : :.:.. :: .. . . . : ::: ::. . :.: CCDS13 -R------LDNGTW---VLMDQHMGFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQ 230 240 250 260 270 100 110 120 130 140 150 pF1KB3 NYEVTWYTSWSPCPE--CAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEG :.:::. ::::: ::::: :: ....: : ::.::. : .: :.:.: : . : CCDS13 IYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAG 280 290 300 310 320 330 160 170 180 190 200 pF1KB3 ASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ :.:.:: : .: :: .::: . ::.:: ::. . . :. ::: ::: CCDS13 AQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN 340 350 360 370 380 >>CCDS13984.1 APOBEC3G gene_id:60489|Hs108|chr22 (384 aa) initn: 557 init1: 254 opt: 435 Z-score: 561.7 bits: 111.8 E(32554): 5.8e-25 Smith-Waterman score: 587; 48.8% identity (66.7% similar) in 207 aa overlap (1-202:1-194) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL :.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::: CCDS13 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRG--- 10 20 30 40 50 70 80 90 100 110 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCD-DILSPNTNYEVTWYTSWSPCPECAGEVAEF .: : . : : :. :: : . .:::::: ::::: .:. ..: : CCDS13 ---------QVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATF 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 LARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQ--EG--ASVKIMGYKDFVSCWKNFVYS ::. .:.::::.::: :::: ::::.: :: : .: :..:::.: .: ::..:::: CCDS13 LAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYS 110 120 130 140 150 160 180 190 200 pF1KB3 DDEPFKPWKGLQTNFRLLKRRLREILQ . : :.::..: . ::. : :::. CCDS13 QRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERM 170 180 190 200 210 220 >-- initn: 468 init1: 192 opt: 415 Z-score: 535.9 bits: 107.0 E(32554): 1.6e-23 Smith-Waterman score: 415; 41.2% identity (65.8% similar) in 187 aa overlap (16-202:201-380) 10 20 30 40 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGR :: ::.::: . :: :.:::::. .. CCDS13 LFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHND 180 190 200 210 220 230 50 60 70 80 90 100 pF1KB3 SNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTS . .: . :: . :. :.. : :: :::. . :. . .:.:: .:: CCDS13 TWVLLNQ--RRGFLC--NQAPHKHGFLEGRH--AELCFLDVIPFWKLDLDQDYRVTCFTS 240 250 260 270 280 110 120 130 140 150 160 pF1KB3 WSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDF :::: :: :.:.:......:.: :::::. : . :::: .:.. ::...:: :..: CCDS13 WSPCFSCAQEMAKFISKNKHVSLCIFTARI-YDDQGRCQEGLRTLAEAGAKISIMTYSEF 290 300 310 320 330 340 170 180 190 200 pF1KB3 VSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ :: .:: . ::.:: ::. . . :. ::: ::: CCDS13 KHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN 350 360 370 380 >>CCDS41747.1 AICDA gene_id:57379|Hs108|chr12 (198 aa) initn: 434 init1: 221 opt: 384 Z-score: 500.1 bits: 99.4 E(32554): 1.5e-21 Smith-Waterman score: 424; 38.7% identity (61.3% similar) in 191 aa overlap (12-201:6-180) 10 20 30 40 50 60 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL : : : .:.: :: :.::: :: . . ... : : .:. CCDS41 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRN--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 PKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFL .. ::.: :: .. : :.:. :.:::.:::::: .:: .::.:: CCDS41 -------------KNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFL 60 70 80 90 130 140 150 160 170 pF1KB3 ARHSNVNLTIFTARLCYFWDTDYQ-EGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEP . :..: :::::: . : . ::: : . :... :: .::. ::..:: . .. CCDS41 RGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERT 100 110 120 130 140 150 180 190 200 pF1KB3 FKPWKGLQTNFRLLKRRLREILQ :: :.::. : :.:.::.:: CCDS41 FKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL 160 170 180 190 >>CCDS13981.1 APOBEC3A gene_id:200315|Hs108|chr22 (199 aa) initn: 373 init1: 166 opt: 378 Z-score: 492.4 bits: 98.0 E(32554): 4.2e-21 Smith-Waterman score: 378; 38.6% identity (59.4% similar) in 197 aa overlap (8-202:9-195) 10 20 30 40 50 pF1KB3 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPV : . : : .::.: :: :.:::::. . ... : :: . CCDS13 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYEVERLDNGTSVKMDQ--HRGFL 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 LPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAGEVA ... .. . ::: ::. . :.: :.:::. ::::: ::::: CCDS13 ----HNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDD :: ....: : ::.::. : .: :.:.: : . ::.:.:: : .: :: .:: . CCDS13 AFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQG 120 130 140 150 160 170 180 190 200 pF1KB3 EPFKPWKGLQTNFRLLKRRLREILQ ::.:: ::. . . :. ::: ::: CCDS13 CPFQPWDGLDEHSQALSGRLRAILQNQGN 180 190 >>CCDS13985.1 APOBEC3H gene_id:164668|Hs108|chr22 (183 aa) initn: 337 init1: 296 opt: 342 Z-score: 446.5 bits: 89.4 E(32554): 1.5e-18 Smith-Waterman score: 342; 39.3% identity (66.4% similar) in 140 aa overlap (68-202:44-182) 40 50 60 70 80 90 pF1KB3 EVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTN : . . .:::: ::.. . . :. . CCDS13 NNKRRLRRPYYPRKALLCYQLTPQNGSTPTRGYFENKKKCHAEICFINEIKSMGLDETQC 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB3 YEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASV :.:: : .:::: :: :...:. :...:: ::..:: : : :.:: : . : CCDS13 YQVTCYLTWSPCSSCAWELVDFIKAHDHLNLGIFASRLYYHWCKPQQKGLRLLCGSQVPV 80 90 100 110 120 130 160 170 180 190 200 pF1KB3 KIMGYKDFVSCWKNFVYSDDEP--FKPWKGLQT---NFRLLKRRLREILQ ..::. .:..::.::: . ..: :.:.: :. : : .::::..: : CCDS13 EVMGFPEFADCWENFV-DHEKPLSFNPYKMLEELDKNSRAIKRRLERIKQS 140 150 160 170 180 >>CCDS54531.1 APOBEC3H gene_id:164668|Hs108|chr22 (182 aa) initn: 333 init1: 296 opt: 338 Z-score: 441.4 bits: 88.4 E(32554): 2.9e-18 Smith-Waterman score: 338; 39.1% identity (66.7% similar) in 138 aa overlap (68-200:44-180) 40 50 60 70 80 90 pF1KB3 EVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVDPETHCHAERCFLSWFCDDILSPNTN : . . .:::: ::.. . . :. . CCDS54 NNKRRLRRPYYPRKALLCYQLTPQNGSTPTRGYFENKKKCHAEICFINEIKSMGLDETQC 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB3 YEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASV :.:: : .:::: :: :...:. :...:: ::..:: : : :.:: : . : CCDS54 YQVTCYLTWSPCSSCAWELVDFIKAHDHLNLGIFASRLYYHWCKPQQKGLRLLCGSQVPV 80 90 100 110 120 130 160 170 180 190 200 pF1KB3 KIMGYKDFVSCWKNFVYSDDEP--FKPWKGLQT---NFRLLKRRLREILQ ..::. .:..::.::: . ..: :.:.: :. : : .::::..: CCDS54 EVMGFPEFADCWENFV-DHEKPLSFNPYKMLEELDKNSRAIKRRLERIKS 140 150 160 170 180 202 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:42:06 2016 done: Fri Nov 4 23:42:06 2016 Total Scan time: 1.980 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]