FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3455, 160 aa 1>>>pF1KB3455 160 - 160 aa - 160 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9809+/-0.000326; mu= 6.4723+/- 0.021 mean_var=152.9298+/-31.233, 0's: 0 Z-trim(120.2): 46 B-trim: 186 in 1/55 Lambda= 0.103712 statistics sampled from 35025 (35075) to 35025 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.411), width: 16 Scan time: 5.950 The best scores are: opt bits E(85289) NP_002373 (OMIM: 154950,171300) protein max isofor ( 160) 1032 164.9 5e-41 NP_660087 (OMIM: 154950,171300) protein max isofor ( 151) 909 146.5 1.7e-35 NP_660088 (OMIM: 154950,171300) protein max isofor ( 103) 648 107.3 7.2e-24 XP_011535075 (OMIM: 154950,171300) PREDICTED: prot ( 153) 648 107.4 9.6e-24 NP_932061 (OMIM: 154950,171300) protein max isofor ( 83) 390 68.6 2.6e-12 NP_660089 (OMIM: 154950,171300) protein max isofor ( 96) 382 67.4 6.5e-12 XP_016876802 (OMIM: 154950,171300) PREDICTED: prot ( 97) 382 67.4 6.6e-12 NP_001307344 (OMIM: 154950,171300) protein max iso ( 97) 382 67.4 6.6e-12 XP_016876801 (OMIM: 154950,171300) PREDICTED: prot ( 97) 382 67.4 6.6e-12 NP_001257998 (OMIM: 154950,171300) protein max iso ( 74) 267 50.1 8.2e-07 NP_001257997 (OMIM: 154950,171300) protein max iso ( 87) 259 49.0 2.1e-06 NP_001280160 (OMIM: 164280,164840,189960) N-myc pr ( 253) 203 41.0 0.0015 XP_016859657 (OMIM: 164280,164840,189960) PREDICTE ( 464) 203 41.3 0.0024 NP_001280157 (OMIM: 164280,164840,189960) N-myc pr ( 464) 203 41.3 0.0024 NP_005369 (OMIM: 164280,164840,189960) N-myc proto ( 464) 203 41.3 0.0024 NP_064706 (OMIM: 603039) max-binding protein MNT [ ( 582) 204 41.5 0.0025 XP_011522170 (OMIM: 603039) PREDICTED: max-binding ( 590) 204 41.5 0.0025 NP_996888 (OMIM: 191523,602491) upstream stimulato ( 251) 195 39.8 0.0035 NP_001263302 (OMIM: 191523,602491) upstream stimul ( 310) 195 39.9 0.004 NP_009053 (OMIM: 191523,602491) upstream stimulato ( 310) 195 39.9 0.004 >>NP_002373 (OMIM: 154950,171300) protein max isoform a (160 aa) initn: 1032 init1: 1032 opt: 1032 Z-score: 857.6 bits: 164.9 E(85289): 5e-41 Smith-Waterman score: 1032; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN 70 80 90 100 110 120 130 140 150 160 pF1KB3 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS :::::::::::::::::::::::::::::::::::::::: NP_002 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS 130 140 150 160 >>NP_660087 (OMIM: 154950,171300) protein max isoform b (151 aa) initn: 909 init1: 909 opt: 909 Z-score: 758.4 bits: 146.5 E(85289): 1.7e-35 Smith-Waterman score: 943; 94.4% identity (94.4% similar) in 160 aa overlap (1-160:1-151) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_660 MSDNDDIEVESD---------ADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN 60 70 80 90 100 110 130 140 150 160 pF1KB3 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS :::::::::::::::::::::::::::::::::::::::: NP_660 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS 120 130 140 150 >>NP_660088 (OMIM: 154950,171300) protein max isoform c (103 aa) initn: 648 init1: 648 opt: 648 Z-score: 549.5 bits: 107.3 E(85289): 7.2e-24 Smith-Waterman score: 648; 100.0% identity (100.0% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN :::::::::::::::::::::::::::::::::::::: NP_660 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGESES 70 80 90 100 130 140 150 160 pF1KB3 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS >>XP_011535075 (OMIM: 154950,171300) PREDICTED: protein (153 aa) initn: 648 init1: 648 opt: 648 Z-score: 547.3 bits: 107.4 E(85289): 9.6e-24 Smith-Waterman score: 648; 100.0% identity (100.0% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN :::::::::::::::::::::::::::::::::::::: XP_011 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGALPAVGITPGIRCLKRALRSL 70 80 90 100 110 120 130 140 150 160 pF1KB3 SLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS XP_011 EWNVLCKYQRLQVFRDSEPSPLSMVVQSGQPMG 130 140 150 >>NP_932061 (OMIM: 154950,171300) protein max isoform f (83 aa) initn: 390 init1: 390 opt: 390 Z-score: 342.1 bits: 68.6 E(85289): 2.6e-12 Smith-Waterman score: 390; 90.5% identity (98.4% similar) in 63 aa overlap (1-63:1-63) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::... NP_932 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKGTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN .. NP_932 MKLTLPPVFPYEHLPFPTVFCHG 70 80 >>NP_660089 (OMIM: 154950,171300) protein max isoform d (96 aa) initn: 394 init1: 382 opt: 382 Z-score: 334.8 bits: 67.4 E(85289): 6.5e-12 Smith-Waterman score: 382; 100.0% identity (100.0% similar) in 57 aa overlap (1-57:1-57) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKLYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN NP_660 LFWKLCTPVLHRQSLMQKCHTFISSYQVHKKKECKI 70 80 90 >>XP_016876802 (OMIM: 154950,171300) PREDICTED: protein (97 aa) initn: 382 init1: 382 opt: 382 Z-score: 334.8 bits: 67.4 E(85289): 6.6e-12 Smith-Waterman score: 382; 93.8% identity (98.5% similar) in 65 aa overlap (96-160:33-97) 70 80 90 100 110 120 pF1KB3 KATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTN ... :::::::::::::::::::::::::: XP_016 FWSSKGKARADQVLCSWGIHFSSSLMEDASKRKFRALEKARSSAQLQTNYPSSDNSLYTN 10 20 30 40 50 60 130 140 150 160 pF1KB3 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS ::::::::::::::::::::::::::::::::::: XP_016 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS 70 80 90 >>NP_001307344 (OMIM: 154950,171300) protein max isoform (97 aa) initn: 382 init1: 382 opt: 382 Z-score: 334.8 bits: 67.4 E(85289): 6.6e-12 Smith-Waterman score: 382; 93.8% identity (98.5% similar) in 65 aa overlap (96-160:33-97) 70 80 90 100 110 120 pF1KB3 KATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTN ... :::::::::::::::::::::::::: NP_001 FWSSKGKARADQVLCSWGIHFSSSLMEDASKRKFRALEKARSSAQLQTNYPSSDNSLYTN 10 20 30 40 50 60 130 140 150 160 pF1KB3 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS ::::::::::::::::::::::::::::::::::: NP_001 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS 70 80 90 >>XP_016876801 (OMIM: 154950,171300) PREDICTED: protein (97 aa) initn: 382 init1: 382 opt: 382 Z-score: 334.8 bits: 67.4 E(85289): 6.6e-12 Smith-Waterman score: 382; 93.8% identity (98.5% similar) in 65 aa overlap (96-160:33-97) 70 80 90 100 110 120 pF1KB3 KATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTN ... :::::::::::::::::::::::::: XP_016 FWSSKGKARADQVLCSWGIHFSSSLMEDASKRKFRALEKARSSAQLQTNYPSSDNSLYTN 10 20 30 40 50 60 130 140 150 160 pF1KB3 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS ::::::::::::::::::::::::::::::::::: XP_016 AKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS 70 80 90 >>NP_001257998 (OMIM: 154950,171300) protein max isoform (74 aa) initn: 334 init1: 267 opt: 267 Z-score: 243.3 bits: 50.1 E(85289): 8.2e-07 Smith-Waterman score: 301; 76.2% identity (84.1% similar) in 63 aa overlap (1-63:1-54) 10 20 30 40 50 60 pF1KB3 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR :::::::::::: ::::::::::::::::::::::::::::::::::::... NP_001 MSDNDDIEVESD---------ADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKGTK 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN .. NP_001 MKLTLPPVFPYEHLPFPTVFCHG 60 70 160 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:29:50 2016 done: Fri Nov 4 02:29:51 2016 Total Scan time: 5.950 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]