FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3456, 359 aa
  1>>>pF1KB3456 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9749+/-0.000384; mu= 17.4931+/- 0.024
 mean_var=56.5884+/-11.639, 0's: 0 Z-trim(110.7): 13  B-trim: 847 in 1/50
 Lambda= 0.170495
 statistics sampled from 19051 (19054) to 19051 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.223), width:  16
 Scan time:  6.200

The best scores are:                                      opt bits E(85289)
NP_005054 (OMIM: 604031) acyl-CoA desaturase [Homo ( 359) 2466 615.0 7.9e-176
NP_001032671 (OMIM: 608370) stearoyl-CoA desaturas ( 330) 1382 348.4 1.4e-95
NP_079182 (OMIM: 608370) stearoyl-CoA desaturase 5 ( 256)  731 188.2 1.7e-47


>>NP_005054 (OMIM: 604031) acyl-CoA desaturase [Homo sap  (359 aa)
 initn: 2466 init1: 2466 opt: 2466  Z-score: 3277.7  bits: 615.0 E(85289): 7.9e-176
Smith-Waterman score: 2466; 99.7% identity (100.0% similar) in 359 aa overlap (1-359:1-359)

               10        20        30        40        50        60
pF1KB3 MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 RLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 HVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLLMCFILPTLVPWYFWGE
       :::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_005 HVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNY
              250       260       270       280       290       300

              310       320       330       340       350         
pF1KB3 HHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
              310       320       330       340       350         

>>NP_001032671 (OMIM: 608370) stearoyl-CoA desaturase 5   (330 aa)
 initn: 1401 init1: 1381 opt: 1382  Z-score: 1837.2  bits: 348.4 E(85289): 1.4e-95
Smith-Waterman score: 1382; 61.0% identity (82.9% similar) in 315 aa overlap (49-355:15-329)

       20        30        40        50        60                70
pF1KB3 TITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSP--------KVE
                                     : :..:     ... : .:        . .
NP_001                 MPGPATDAGKIPFCDAKEEIRAGLESSEGGGGPERPGARGQRQN
                               10        20        30        40    

               80        90       100       110       120       130
pF1KB3 YVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKA
        ::::..:::::::::.:...:::  :  : ::. : ....:::.:::::::::::::.:
NP_001 IVWRNVVLMSLLHLGAVYSLVLIPKAKPLTLLWAYFCFLLAALGVTAGAHRLWSHRSYRA
           50        60        70        80        90       100    

              140       150       160       170       180       190
pF1KB3 RLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKH
       .::::.:: .::.::::::..::.::::::::.::: :::::.::::::::.:::.::::
NP_001 KLPLRIFLAVANSMAFQNDIFEWSRDHRAHHKYSETDADPHNARRGFFFSHIGWLFVRKH
          110       120       130       140       150       160    

              200       210       220       230       240       250
pF1KB3 PAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLLMCFILPTLVPWYFWGETFQNSVFVAT
         : :::  ::..:: :. .: .::.::: ...::::..:::::::.:::.. :: :.:.
NP_001 RDVIEKGRKLDVTDLLADPVVRIQRKYYKISVVLMCFVVPTLVPWYIWGESLWNSYFLAS
          170       180       190       200       210       220    

              260       270       280       290       300       310
pF1KB3 FLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSA
       .:::.. :: .::::::::..: :::::.::::.: ::.:::.:::::::::.::.::::
NP_001 ILRYTISLNISWLVNSAAHMYGNRPYDKHISPRQNPLVALGAIGEGFHNYHHTFPFDYSA
          230       240       250       260       270       280    

              320       330       340       350         
pF1KB3 SEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
       ::.  ..: ::.::: :  :::: :::...:  : ::  ::::..    
NP_001 SEFGLNFNPTTWFIDFMCWLGLATDRKRATKPMIEARKARTGDSSA   
          290       300       310       320       330   

>>NP_079182 (OMIM: 608370) stearoyl-CoA desaturase 5 iso  (256 aa)
 initn: 730 init1: 730 opt: 731  Z-score: 973.5  bits: 188.2 E(85289): 1.7e-47
Smith-Waterman score: 731; 58.9% identity (80.0% similar) in 175 aa overlap (49-215:15-189)

       20        30        40        50        60                70
pF1KB3 TITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSP--------KVE
                                     : :..:     ... : .:        . .
NP_079                 MPGPATDAGKIPFCDAKEEIRAGLESSEGGGGPERPGARGQRQN
                               10        20        30        40    

               80        90       100       110       120       130
pF1KB3 YVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKA
        ::::..:::::::::.:...:::  :  : ::. : ....:::.:::::::::::::.:
NP_079 IVWRNVVLMSLLHLGAVYSLVLIPKAKPLTLLWAYFCFLLAALGVTAGAHRLWSHRSYRA
           50        60        70        80        90       100    

              140       150       160       170       180       190
pF1KB3 RLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKH
       .::::.:: .::.::::::..::.::::::::.::: :::::.::::::::.:::.::::
NP_079 KLPLRIFLAVANSMAFQNDIFEWSRDHRAHHKYSETDADPHNARRGFFFSHIGWLFVRKH
          110       120       130       140       150       160    

              200       210       220       230       240       250
pF1KB3 PAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLLMCFILPTLVPWYFWGETFQNSVFVAT
         : :::  ::..:: :. .: .::                                   
NP_079 RDVIEKGRKLDVTDLLADPVVRIQRNTQHIQKEGRALNQEAACEMLREWHQGHILKVTLP
          170       180       190       200       210       220    




359 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:07:01 2016 done: Sat Nov  5 05:07:02 2016
 Total Scan time:  6.200 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]