FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3465, 345 aa 1>>>pF1KB3465 345 - 345 aa - 345 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.3991+/-0.000437; mu= -15.0253+/- 0.027 mean_var=560.7353+/-124.761, 0's: 0 Z-trim(123.4): 950 B-trim: 0 in 0/55 Lambda= 0.054162 statistics sampled from 41774 (43207) to 41774 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.807), E-opt: 0.2 (0.507), width: 16 Scan time: 9.580 The best scores are: opt bits E(85289) NP_057615 (OMIM: 609392) Krueppel-like factor 3 [H ( 345) 2404 202.0 1.5e-51 XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-li ( 320) 2232 188.6 1.6e-47 XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-li ( 352) 668 66.4 1.1e-10 XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 668 66.4 1.1e-10 XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 668 66.4 1.1e-10 XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-li ( 393) 668 66.4 1.2e-10 XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-li ( 400) 668 66.5 1.2e-10 NP_009180 (OMIM: 607531) Krueppel-like factor 12 [ ( 402) 668 66.5 1.2e-10 XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 668 66.5 1.2e-10 XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 668 66.5 1.2e-10 XP_011533209 (OMIM: 607531) PREDICTED: Krueppel-li ( 415) 668 66.5 1.2e-10 NP_001311034 (OMIM: 300286) Krueppel-like factor 8 ( 356) 665 66.2 1.3e-10 NP_001311031 (OMIM: 300286) Krueppel-like factor 8 ( 359) 665 66.2 1.3e-10 XP_005262036 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 665 66.2 1.3e-10 NP_009181 (OMIM: 300286) Krueppel-like factor 8 is ( 359) 665 66.2 1.3e-10 XP_005262034 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 665 66.2 1.3e-10 NP_001311033 (OMIM: 300286) Krueppel-like factor 8 ( 364) 665 66.2 1.3e-10 XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 655 65.4 2.2e-10 XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 655 65.4 2.2e-10 NP_001273747 (OMIM: 602903) Krueppel-like factor 5 ( 366) 624 63.0 1.2e-09 NP_001721 (OMIM: 602903) Krueppel-like factor 5 is ( 457) 624 63.1 1.4e-09 NP_001291 (OMIM: 176807,602053,613659) Krueppel-li ( 283) 576 59.1 1.3e-08 NP_004226 (OMIM: 602253) Krueppel-like factor 4 is ( 479) 582 59.8 1.4e-08 NP_001257872 (OMIM: 604865) Krueppel-like factor 7 ( 269) 558 57.7 3.4e-08 NP_001257873 (OMIM: 604865) Krueppel-like factor 7 ( 274) 558 57.7 3.5e-08 XP_016860650 (OMIM: 604865) PREDICTED: Krueppel-li ( 302) 558 57.7 3.7e-08 NP_003700 (OMIM: 604865) Krueppel-like factor 7 is ( 302) 558 57.7 3.7e-08 XP_011510376 (OMIM: 604865) PREDICTED: Krueppel-li ( 270) 546 56.7 6.6e-08 XP_011510375 (OMIM: 604865) PREDICTED: Krueppel-li ( 272) 546 56.7 6.7e-08 XP_016860651 (OMIM: 604865) PREDICTED: Krueppel-li ( 275) 546 56.7 6.7e-08 XP_011510374 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 546 56.8 7.2e-08 XP_006712878 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 546 56.8 7.2e-08 XP_005246983 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 546 56.8 7.2e-08 NP_001300981 (OMIM: 602253) Krueppel-like factor 4 ( 513) 543 56.8 1.2e-07 NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 529 55.5 2e-07 XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 505 53.6 6.9e-07 NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 505 53.7 7.4e-07 XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 473 51.2 4.6e-06 NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 473 51.2 4.6e-06 XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 473 51.3 4.8e-06 XP_011539002 (OMIM: 609602) PREDICTED: Krueppel-li ( 352) 466 50.6 6e-06 NP_775755 (OMIM: 609602) Krueppel-like factor 17 [ ( 389) 466 50.7 6.4e-06 NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 457 49.8 8.6e-06 NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 460 50.3 1e-05 NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 460 50.3 1e-05 NP_001197 (OMIM: 602902) Krueppel-like factor 9 [H ( 244) 440 48.4 1.9e-05 NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 448 49.4 2e-05 NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 448 49.4 2e-05 NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 448 49.4 2.1e-05 NP_000369 (OMIM: 106210,136680,156240,194070,19407 ( 497) 437 48.5 3.7e-05 >>NP_057615 (OMIM: 609392) Krueppel-like factor 3 [Homo (345 aa) initn: 2404 init1: 2404 opt: 2404 Z-score: 1046.3 bits: 202.0 E(85289): 1.5e-51 Smith-Waterman score: 2404; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK 250 260 270 280 290 300 310 320 330 340 pF1KB3 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::::::::::::::::::::::::::: NP_057 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV 310 320 330 340 >>XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-like f (320 aa) initn: 2232 init1: 2232 opt: 2232 Z-score: 974.0 bits: 188.6 E(85289): 1.6e-47 Smith-Waterman score: 2232; 100.0% identity (100.0% similar) in 320 aa overlap (26-345:1-320) 10 20 30 40 50 60 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME ::::::::::::::::::::::::::::::::::: XP_016 MESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME 10 20 30 70 80 90 100 110 120 pF1KB3 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK 220 230 240 250 260 270 310 320 330 340 pF1KB3 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV 280 290 300 310 320 >>XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-like f (352 aa) initn: 786 init1: 645 opt: 668 Z-score: 313.0 bits: 66.4 E(85289): 1.1e-10 Smith-Waterman score: 776; 43.8% identity (65.5% similar) in 336 aa overlap (58-345:28-352) 30 40 50 60 70 80 pF1KB3 SMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL---- : :::::..:: :.:: ....:: :. XP_016 MEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASA 10 20 30 40 50 90 100 110 120 130 140 pF1KB3 KFPSSHRRASPGLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGI . ::: .: . : .::: : . : : . .. :. :..:.: :. . . XP_016 SSPSSTSTSSSSSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQF 60 70 80 90 100 110 150 160 170 180 190 pF1KB3 LPVIQPVV-VQPVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEK : .:.:: .:. .. . ::... :.. . . : .... ::..:. . XP_016 LHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR- 120 130 140 150 160 200 210 220 230 240 pF1KB3 PISQKKIKIEP-GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQ .. : ...: :. :. ..: ... ..::. :: .:: ::: . . XP_016 --GHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSR 170 180 190 200 210 220 250 260 270 pF1KB3 P-GKR-----------PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKA :.: :. .:: ::. :::::::::..:::::::::::::: XP_016 VRGNRMNNQKFPCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB3 HRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHR :::::::::::::::::::::::::::::::.:::::.:::.: :::::::::::::::: XP_016 HRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHR 290 300 310 320 330 340 340 pF1KB3 KRHMLV .::::: XP_016 RRHMLV 350 >>XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-like f (383 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.6 bits: 66.4 E(85289): 1.1e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:17-383) 10 20 30 40 50 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEG ...: .: .::. ::.. : . . . : :: ... . XP_011 MLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVKGEP-PEDSLSVDH- 10 20 30 40 50 60 70 80 90 100 pF1KB3 LSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASPGLSMPSSSPP-IKK : :::::..:: :.:: ....:: :. . ::: .: . : .::: : . XP_011 --FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 YSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQPVPFMYT--SHLQQ : : . .. :. :..:.: :. . .: .:.:: .:. .. . ::... XP_011 VSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHR 120 130 140 150 160 170 180 190 200 210 pF1KB3 --------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP-GIEPQ--RTDYYP :.. . . : .... ::..:. . .. : ...: :. :. ..: XP_011 IPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDPRGLSPRQSKSDSDD 170 180 190 200 210 220 220 230 240 250 pF1KB3 EEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR-----------PLPVES--- ... ..::. :: .:: ::: . . :.: :. .:: XP_011 DDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRR 230 240 250 260 270 280 260 270 280 290 300 pF1KB3 ------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARS ::. :::::::::..::::::::::::::::::::::::::::::::::::::: XP_011 QRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARS 290 300 310 320 330 340 310 320 330 340 pF1KB3 DELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::.:::::.:::.: ::::::::::::::::.::::: XP_011 DELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 >>XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-like f (383 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.6 bits: 66.4 E(85289): 1.1e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:17-383) 10 20 30 40 50 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEG ...: .: .::. ::.. : . . . : :: ... . XP_011 MLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVKGEP-PEDSLSVDH- 10 20 30 40 50 60 70 80 90 100 pF1KB3 LSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASPGLSMPSSSPP-IKK : :::::..:: :.:: ....:: :. . ::: .: . : .::: : . XP_011 --FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 YSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQPVPFMYT--SHLQQ : : . .. :. :..:.: :. . .: .:.:: .:. .. . ::... XP_011 VSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHR 120 130 140 150 160 170 180 190 200 210 pF1KB3 --------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP-GIEPQ--RTDYYP :.. . . : .... ::..:. . .. : ...: :. :. ..: XP_011 IPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDPRGLSPRQSKSDSDD 170 180 190 200 210 220 220 230 240 250 pF1KB3 EEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR-----------PLPVES--- ... ..::. :: .:: ::: . . :.: :. .:: XP_011 DDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRR 230 240 250 260 270 280 260 270 280 290 300 pF1KB3 ------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARS ::. :::::::::..::::::::::::::::::::::::::::::::::::::: XP_011 QRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARS 290 300 310 320 330 340 310 320 330 340 pF1KB3 DELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::.:::::.:::.: ::::::::::::::::.::::: XP_011 DELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 >>XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-like f (393 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.5 bits: 66.4 E(85289): 1.2e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:27-393) 10 20 30 40 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPL ...: .: .::. ::.. : . . . : XP_016 MVNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVKGEP- 10 20 30 40 50 50 60 70 80 90 pF1KB3 PEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASPGLSM :: ... . : :::::..:: :.:: ....:: :. . ::: .: . : XP_016 PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSR 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 PSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQPVPF .::: : . : : . .. :. :..:.: :. . .: .:.:: .:. . XP_016 LASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSSPMNL 120 130 140 150 160 160 170 180 190 200 pF1KB3 MYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP-GIE . . ::... :.. . . : .... ::..:. . .. : ...: :. XP_016 QSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDPRGLS 170 180 190 200 210 220 210 220 230 240 pF1KB3 PQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR---------- :. ..: ... ..::. :: .:: ::: . . :.: XP_016 PRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSI 230 240 250 260 270 280 250 260 270 280 290 pF1KB3 -PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTW :. .:: ::. :::::::::..::::::::::::::::::::::::::::: XP_016 SPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTW 290 300 310 320 330 340 300 310 320 330 340 pF1KB3 EGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::.:::::.:::.: ::::::::::::::::.::::: XP_016 EGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 390 >>XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-like f (400 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.4 bits: 66.5 E(85289): 1.2e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:34-400) 10 20 30 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIY ...: .: .::. ::.. : . . XP_011 VQACGTNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 STPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASP . : :: ... . : :::::..:: :.:: ....:: :. . ::: .: XP_011 GEP-PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSS 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 GLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQ . : .::: : . : : . .. :. :..:.: :. . .: .:.:: . XP_011 SSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSS 120 130 140 150 160 160 170 180 190 200 pF1KB3 PVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP :. .. . ::... :.. . . : .... ::..:. . .. : ...: XP_011 PMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDP 170 180 190 200 210 220 210 220 230 240 pF1KB3 -GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR------ :. :. ..: ... ..::. :: .:: ::: . . :.: XP_011 RGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKF 230 240 250 260 270 280 250 260 270 280 290 pF1KB3 -----PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPY :. .:: ::. :::::::::..::::::::::::::::::::::::: XP_011 PCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPY 290 300 310 320 330 340 300 310 320 330 340 pF1KB3 KCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::.:::::.:::.: ::::::::::::::::.::::: XP_011 KCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 390 400 >>NP_009180 (OMIM: 607531) Krueppel-like factor 12 [Homo (402 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.3 bits: 66.5 E(85289): 1.2e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:36-402) 10 20 30 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIY ...: .: .::. ::.. : . . NP_009 KRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 STPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASP . : :: ... . : :::::..:: :.:: ....:: :. . ::: .: NP_009 GEP-PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSS 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 GLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQ . : .::: : . : : . .. :. :..:.: :. . .: .:.:: . NP_009 SSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSS 120 130 140 150 160 170 160 170 180 190 200 pF1KB3 PVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP :. .. . ::... :.. . . : .... ::..:. . .. : ...: NP_009 PMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDP 180 190 200 210 220 210 220 230 240 pF1KB3 -GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR------ :. :. ..: ... ..::. :: .:: ::: . . :.: NP_009 RGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKF 230 240 250 260 270 280 250 260 270 280 290 pF1KB3 -----PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPY :. .:: ::. :::::::::..::::::::::::::::::::::::: NP_009 PCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPY 290 300 310 320 330 340 300 310 320 330 340 pF1KB3 KCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::.:::::.:::.: ::::::::::::::::.::::: NP_009 KCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 390 400 >>XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-like f (402 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.3 bits: 66.5 E(85289): 1.2e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:36-402) 10 20 30 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIY ...: .: .::. ::.. : . . XP_011 KRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 STPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASP . : :: ... . : :::::..:: :.:: ....:: :. . ::: .: XP_011 GEP-PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSS 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 GLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQ . : .::: : . : : . .. :. :..:.: :. . .: .:.:: . XP_011 SSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSS 120 130 140 150 160 170 160 170 180 190 200 pF1KB3 PVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP :. .. . ::... :.. . . : .... ::..:. . .. : ...: XP_011 PMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDP 180 190 200 210 220 210 220 230 240 pF1KB3 -GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR------ :. :. ..: ... ..::. :: .:: ::: . . :.: XP_011 RGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKF 230 240 250 260 270 280 250 260 270 280 290 pF1KB3 -----PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPY :. .:: ::. :::::::::..::::::::::::::::::::::::: XP_011 PCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPY 290 300 310 320 330 340 300 310 320 330 340 pF1KB3 KCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::.:::::.:::.: ::::::::::::::::.::::: XP_011 KCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 390 400 >>XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-like f (402 aa) initn: 786 init1: 645 opt: 668 Z-score: 312.3 bits: 66.5 E(85289): 1.2e-10 Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:36-402) 10 20 30 pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIY ...: .: .::. ::.. : . . XP_005 KRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 STPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASP . : :: ... . : :::::..:: :.:: ....:: :. . ::: .: XP_005 GEP-PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSS 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 GLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQ . : .::: : . : : . .. :. :..:.: :. . .: .:.:: . XP_005 SSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSS 120 130 140 150 160 170 160 170 180 190 200 pF1KB3 PVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP :. .. . ::... :.. . . : .... ::..:. . .. : ...: XP_005 PMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDP 180 190 200 210 220 210 220 230 240 pF1KB3 -GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR------ :. :. ..: ... ..::. :: .:: ::: . . :.: XP_005 RGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKF 230 240 250 260 270 280 250 260 270 280 290 pF1KB3 -----PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPY :. .:: ::. :::::::::..::::::::::::::::::::::::: XP_005 PCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPY 290 300 310 320 330 340 300 310 320 330 340 pF1KB3 KCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV ::::::::::::::::::::.:::::.:::.: ::::::::::::::::.::::: XP_005 KCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV 350 360 370 380 390 400 345 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:19:21 2016 done: Thu Nov 3 13:19:23 2016 Total Scan time: 9.580 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]