FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3466, 577 aa 1>>>pF1KB3466 577 - 577 aa - 577 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.6904+/-0.000805; mu= -33.7012+/- 0.050 mean_var=813.5227+/-164.899, 0's: 0 Z-trim(116.8): 319 B-trim: 0 in 0/55 Lambda= 0.044967 statistics sampled from 27860 (28179) to 27860 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.33), width: 16 Scan time: 7.430 The best scores are: opt bits E(85289) NP_002435 (OMIM: 309845) moesin [Homo sapiens] ( 577) 3721 257.5 8.9e-68 XP_005262326 (OMIM: 309845) PREDICTED: moesin isof ( 578) 3693 255.7 3.1e-67 XP_011529261 (OMIM: 309845) PREDICTED: moesin isof ( 610) 3693 255.7 3.3e-67 XP_016885035 (OMIM: 309845) PREDICTED: moesin isof ( 566) 3656 253.2 1.6e-66 XP_016885034 (OMIM: 309845) PREDICTED: moesin isof ( 566) 3656 253.2 1.6e-66 NP_002897 (OMIM: 179410,611022) radixin isoform 2 ( 583) 3117 218.3 5.6e-56 NP_001247422 (OMIM: 179410,611022) radixin isoform ( 604) 3117 218.3 5.7e-56 NP_001247421 (OMIM: 179410,611022) radixin isoform ( 604) 3117 218.3 5.7e-56 NP_003370 (OMIM: 123900) ezrin [Homo sapiens] ( 586) 2484 177.2 1.3e-43 NP_001104547 (OMIM: 123900) ezrin [Homo sapiens] ( 586) 2484 177.2 1.3e-43 NP_001247423 (OMIM: 179410,611022) radixin isoform ( 447) 2192 158.2 5.3e-38 NP_000259 (OMIM: 101000,162091,607174,607379) merl ( 595) 1688 125.6 4.6e-28 NP_861546 (OMIM: 101000,162091,607174,607379) merl ( 590) 1663 124.0 1.4e-27 NP_861970 (OMIM: 101000,162091,607174,607379) merl ( 590) 1663 124.0 1.4e-27 NP_057502 (OMIM: 101000,162091,607174,607379) merl ( 590) 1663 124.0 1.4e-27 XP_016884298 (OMIM: 101000,162091,607174,607379) P ( 557) 1609 120.4 1.5e-26 XP_011534412 (OMIM: 123900) PREDICTED: ezrin isofo ( 450) 1594 119.4 2.5e-26 XP_016884299 (OMIM: 101000,162091,607174,607379) P ( 552) 1584 118.8 4.6e-26 NP_861966 (OMIM: 101000,162091,607174,607379) merl ( 548) 1432 109.0 4.3e-23 NP_861969 (OMIM: 101000,162091,607174,607379) merl ( 507) 1256 97.5 1.1e-19 NP_861968 (OMIM: 101000,162091,607174,607379) merl ( 507) 1256 97.5 1.1e-19 NP_861967 (OMIM: 101000,162091,607174,607379) merl ( 549) 1251 97.2 1.5e-19 NP_001247424 (OMIM: 179410,611022) radixin isoform ( 257) 988 79.9 1.1e-14 NP_001247425 (OMIM: 179410,611022) radixin isoform ( 200) 600 54.6 3.6e-07 NP_861971 (OMIM: 101000,162091,607174,607379) merl ( 165) 547 51.1 3.3e-06 NP_060497 (OMIM: 616305,616819) FERM domain-contai (1039) 488 47.9 0.00019 XP_016871884 (OMIM: 616305,616819) PREDICTED: FERM (1046) 488 47.9 0.00019 XP_016871883 (OMIM: 616305,616819) PREDICTED: FERM (1050) 488 48.0 0.00019 NP_001305265 (OMIM: 616305,616819) FERM domain-con (1055) 488 48.0 0.00019 XP_011517845 (OMIM: 616305,616819) PREDICTED: FERM (1062) 488 48.0 0.00019 NP_001305266 (OMIM: 616305,616819) FERM domain-con (1072) 488 48.0 0.00019 XP_005252547 (OMIM: 616305,616819) PREDICTED: FERM (1078) 488 48.0 0.00019 XP_005252546 (OMIM: 616305,616819) PREDICTED: FERM (1083) 488 48.0 0.00019 XP_006717523 (OMIM: 616305,616819) PREDICTED: FERM (1095) 488 48.0 0.0002 NP_001159478 (OMIM: 130500,611804) protein 4.1 iso ( 720) 463 46.2 0.00044 NP_976217 (OMIM: 130500,611804) protein 4.1 isofor ( 641) 460 46.0 0.00046 XP_016856093 (OMIM: 130500,611804) PREDICTED: prot ( 523) 455 45.6 0.0005 XP_005245820 (OMIM: 130500,611804) PREDICTED: prot ( 850) 463 46.3 0.0005 XP_016856081 (OMIM: 130500,611804) PREDICTED: prot ( 732) 458 45.9 0.00056 XP_011539261 (OMIM: 130500,611804) PREDICTED: prot (1017) 463 46.3 0.00057 XP_005245827 (OMIM: 130500,611804) PREDICTED: prot ( 809) 458 45.9 0.0006 XP_016856086 (OMIM: 130500,611804) PREDICTED: prot ( 767) 455 45.7 0.00066 XP_016856092 (OMIM: 130500,611804) PREDICTED: prot ( 524) 448 45.1 0.00068 XP_016856072 (OMIM: 130500,611804) PREDICTED: prot ( 976) 458 46.0 0.00069 NP_001159479 (OMIM: 130500,611804) protein 4.1 iso ( 601) 448 45.2 0.00075 XP_016856080 (OMIM: 130500,611804) PREDICTED: prot ( 733) 451 45.4 0.00077 XP_005245831 (OMIM: 130500,611804) PREDICTED: prot ( 767) 451 45.4 0.00079 XP_005245826 (OMIM: 130500,611804) PREDICTED: prot ( 810) 451 45.5 0.00083 XP_016856085 (OMIM: 130500,611804) PREDICTED: prot ( 768) 448 45.2 0.00091 XP_016856074 (OMIM: 130500,611804) PREDICTED: prot ( 977) 451 45.5 0.00095 >>NP_002435 (OMIM: 309845) moesin [Homo sapiens] (577 aa) initn: 3721 init1: 3721 opt: 3721 Z-score: 1337.8 bits: 257.5 E(85289): 8.9e-68 Smith-Waterman score: 3721; 100.0% identity (100.0% similar) in 577 aa overlap (1-577:1-577) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA 490 500 510 520 530 540 550 560 570 pF1KB3 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM ::::::::::::::::::::::::::::::::::::: NP_002 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 550 560 570 >>XP_005262326 (OMIM: 309845) PREDICTED: moesin isoform (578 aa) initn: 3693 init1: 3693 opt: 3693 Z-score: 1328.0 bits: 255.7 E(85289): 3.1e-67 Smith-Waterman score: 3693; 100.0% identity (100.0% similar) in 573 aa overlap (5-577:6-578) 10 20 30 40 50 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQNNQISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 KLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 ETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 RGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 IEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLAL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 EMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 QDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKT 490 500 510 520 530 540 540 550 560 570 pF1KB3 ANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM :::::::::::::::::::::::::::::::::::::: XP_005 ANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 550 560 570 >>XP_011529261 (OMIM: 309845) PREDICTED: moesin isoform (610 aa) initn: 3693 init1: 3693 opt: 3693 Z-score: 1327.7 bits: 255.7 E(85289): 3.3e-67 Smith-Waterman score: 3693; 100.0% identity (100.0% similar) in 573 aa overlap (5-577:38-610) 10 20 30 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVV :::::::::::::::::::::::::::::: XP_011 RSAQDQVPGELESITTTVRSTDPQASFSSQISVRVTTMDAELEFAIQPNTTGKQLFDQVV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 KTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB3 QDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 QRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB3 ELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB3 RINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB3 KEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB3 EAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQE 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB3 DLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB3 NERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEF 550 560 570 580 590 600 pF1KB3 ESM ::: XP_011 ESM 610 >>XP_016885035 (OMIM: 309845) PREDICTED: moesin isoform (566 aa) initn: 3656 init1: 3656 opt: 3656 Z-score: 1315.2 bits: 253.2 E(85289): 1.6e-66 Smith-Waterman score: 3656; 100.0% identity (100.0% similar) in 566 aa overlap (12-577:1-566) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK 10 20 30 40 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA 470 480 490 500 510 520 550 560 570 pF1KB3 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM ::::::::::::::::::::::::::::::::::::: XP_016 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 530 540 550 560 >>XP_016885034 (OMIM: 309845) PREDICTED: moesin isoform (566 aa) initn: 3656 init1: 3656 opt: 3656 Z-score: 1315.2 bits: 253.2 E(85289): 1.6e-66 Smith-Waterman score: 3656; 100.0% identity (100.0% similar) in 566 aa overlap (12-577:1-566) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK 10 20 30 40 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTA 470 480 490 500 510 520 550 560 570 pF1KB3 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM ::::::::::::::::::::::::::::::::::::: XP_016 NDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 530 540 550 560 >>NP_002897 (OMIM: 179410,611022) radixin isoform 2 [Hom (583 aa) initn: 3252 init1: 2675 opt: 3117 Z-score: 1126.0 bits: 218.3 E(85289): 5.6e-56 Smith-Waterman score: 3117; 81.0% identity (93.5% similar) in 583 aa overlap (1-577:1-583) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::: :.::::::::::::::::::::::::::::::.:::::::::::: :.::.::::: NP_002 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::: :::.::.:: :::::::.::::::::::.::::::::::::.::::.:::::: NP_002 LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::.::::.:::.:: ::::.:.::::::::::::.:.::::::: :::::: NP_002 TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF ::::::...::::::::::::::::: ::::::.:::::::::::::::..:.::::::: NP_002 GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::.:::.:::::::::.::::::.::::::::::::::::::: : NP_002 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE ::.:::::::.::::.::::::. :::.: :::. ::::: :. . . :: :.::::: : NP_002 AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH------VAE .::.::.:. :: :..::: ::.:::.:: .:::::::. ::::.::.: : NP_002 LAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 PAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARD :.:::.::.:::.:::::.: ... . ::::::.::..:::::.:.:.::.::::.::: NP_002 PTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARD 490 500 510 520 530 540 540 550 560 570 pF1KB3 ESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM :.::: ::..::::.. ::::::::::::::::::::::::.: NP_002 ETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 550 560 570 580 >>NP_001247422 (OMIM: 179410,611022) radixin isoform 1 [ (604 aa) initn: 3252 init1: 2675 opt: 3117 Z-score: 1125.8 bits: 218.3 E(85289): 5.7e-56 Smith-Waterman score: 3117; 81.0% identity (93.5% similar) in 583 aa overlap (1-577:1-583) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::: :.::::::::::::::::::::::::::::::.:::::::::::: :.::.::::: NP_001 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::: :::.::.:: :::::::.::::::::::.::::::::::::.::::.:::::: NP_001 LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::.::::.:::.:: ::::.:.::::::::::::.:.::::::: :::::: NP_001 TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF ::::::...::::::::::::::::: ::::::.:::::::::::::::..:.::::::: NP_001 GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::.:::.:::::::::.::::::.::::::::::::::::::: : NP_001 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE ::.:::::::.::::.::::::. :::.: :::. ::::: :. . . :: :.::::: : NP_001 AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH------VAE .::.::.:. :: :..::: ::.:::.:: .:::::::. ::::.::.: : NP_001 LAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 PAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARD :.:::.::.:::.:::::.: ... . ::::::.::..:::::.:.:.::.::::.::: NP_001 PTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARD 490 500 510 520 530 540 540 550 560 570 pF1KB3 ESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM :.::: ::..::::.. ::::::::::::::::::::::::.: NP_001 ETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSS 550 560 570 580 590 600 NP_001 IKQM >>NP_001247421 (OMIM: 179410,611022) radixin isoform 1 [ (604 aa) initn: 3252 init1: 2675 opt: 3117 Z-score: 1125.8 bits: 218.3 E(85289): 5.7e-56 Smith-Waterman score: 3117; 81.0% identity (93.5% similar) in 583 aa overlap (1-577:1-583) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::: :.::::::::::::::::::::::::::::::.:::::::::::: :.::.::::: NP_001 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :::::: :::.::.:: :::::::.::::::::::.::::::::::::.::::.:::::: NP_001 LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::::::::.::::.:::.:: ::::.:.::::::::::::.:.::::::: :::::: NP_001 TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF ::::::...::::::::::::::::: ::::::.:::::::::::::::..:.::::::: NP_001 GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::.:::.:::::::::.::::::.::::::::::::::::::: : NP_001 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE ::.:::::::.::::.::::::. :::.: :::. ::::: :. . . :: :.::::: : NP_001 AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH------VAE .::.::.:. :: :..::: ::.:::.:: .:::::::. ::::.::.: : NP_001 LAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 PAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARD :.:::.::.:::.:::::.: ... . ::::::.::..:::::.:.:.::.::::.::: NP_001 PTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARD 490 500 510 520 530 540 540 550 560 570 pF1KB3 ESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM :.::: ::..::::.. ::::::::::::::::::::::::.: NP_001 ETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSS 550 560 570 580 590 600 NP_001 IKQM >>NP_003370 (OMIM: 123900) ezrin [Homo sapiens] (586 aa) initn: 2983 init1: 2457 opt: 2484 Z-score: 904.1 bits: 177.2 E(85289): 1.3e-43 Smith-Waterman score: 2852; 73.6% identity (90.1% similar) in 587 aa overlap (1-577:1-586) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::: :.:::::::::::::::::::::::::::::::::::::.:::.: :.::: :::: NP_003 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :.:::.::.::::.:: ::::::::::::.:::::::::.:::::::::::.:.:::::: NP_003 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::.:::::.:.::.::::::::::....:.::::..::::..::::.:::::: ::: NP_003 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF :::...:.::::::::::::::.::: ::::::..::::::::::::::..:.::::::: NP_003 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: NP_003 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::.:: .::.:::.:: .:.:::.. ::::::: ::.. ::.::: NP_003 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE :..:: :: .:::.::.:::::: :::.: .:. : .::: : . . :: :.::::: : NP_003 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH-----VAEP .:: ::.:. :: ::..::.:. :::..:. .:.:: ::. ::. .:..: : :: NP_003 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 AENEQDE--QDENGAEA---SADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELA . . .: ::: ::: ::.: .... ::.::.: ::::::::::..: .:.:::. NP_003 VSYHVQESLQDE-GAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELS 490 500 510 520 530 540 550 560 570 pF1KB3 NARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM .::::.:.: ::.:: :::: ::::::::::::::::::::::::.. NP_003 QARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 540 550 560 570 580 >>NP_001104547 (OMIM: 123900) ezrin [Homo sapiens] (586 aa) initn: 2983 init1: 2457 opt: 2484 Z-score: 904.1 bits: 177.2 E(85289): 1.3e-43 Smith-Waterman score: 2852; 73.6% identity (90.1% similar) in 587 aa overlap (1-577:1-586) 10 20 30 40 50 60 pF1KB3 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK ::: :.:::::::::::::::::::::::::::::::::::::.:::.: :.::: :::: NP_001 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE :.:::.::.::::.:: ::::::::::::.:::::::::.:::::::::::.:.:::::: NP_001 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR :::::.:::::.:.::.::::::::::....:.::::..::::..::::.:::::: ::: NP_001 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF :::...:.::::::::::::::.::: ::::::..::::::::::::::..:.::::::: NP_001 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: NP_001 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK :::::::::::::::::.:: .::.:::.:: .:.:::.. ::::::: ::.. ::.::: NP_001 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALE :..:: :: .:::.::.:::::: :::.: .:. : .::: : . . :: :.::::: : NP_001 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 MAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH-----VAEP .:: ::.:. :: ::..::.:. :::..:. .:.:: ::. ::. .:..: : :: NP_001 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 AENEQDE--QDENGAEA---SADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELA . . .: ::: ::: ::.: .... ::.::.: ::::::::::..: .:.:::. NP_001 VSYHVQESLQDE-GAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELS 490 500 510 520 530 540 550 560 570 pF1KB3 NARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM .::::.:.: ::.:: :::: ::::::::::::::::::::::::.. NP_001 QARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 540 550 560 570 580 577 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:14:44 2016 done: Fri Nov 4 23:14:46 2016 Total Scan time: 7.430 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]