FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3473, 497 aa 1>>>pF1KB3473 497 - 497 aa - 497 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.8686+/-0.000413; mu= -15.5213+/- 0.026 mean_var=438.4873+/-92.042, 0's: 0 Z-trim(124.5): 84 B-trim: 2264 in 2/58 Lambda= 0.061249 statistics sampled from 46322 (46407) to 46322 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.544), width: 16 Scan time: 11.160 The best scores are: opt bits E(85289) NP_001124398 (OMIM: 600660,608320) myocyte-specifi ( 497) 3341 309.2 1.8e-83 NP_001165365 (OMIM: 600660,608320) myocyte-specifi ( 497) 3341 309.2 1.8e-83 XP_005254972 (OMIM: 600660,608320) PREDICTED: myoc ( 497) 3341 309.2 1.8e-83 XP_011519885 (OMIM: 600660,608320) PREDICTED: myoc ( 505) 3315 306.9 9e-83 NP_001306135 (OMIM: 600660,608320) myocyte-specifi ( 505) 3315 306.9 9e-83 NP_005578 (OMIM: 600660,608320) myocyte-specific e ( 499) 3129 290.4 7.9e-78 XP_016877682 (OMIM: 600660,608320) PREDICTED: myoc ( 499) 3129 290.4 7.9e-78 XP_016877683 (OMIM: 600660,608320) PREDICTED: myoc ( 499) 3129 290.4 7.9e-78 XP_016877681 (OMIM: 600660,608320) PREDICTED: myoc ( 503) 3119 289.5 1.5e-77 XP_005254971 (OMIM: 600660,608320) PREDICTED: myoc ( 503) 3119 289.5 1.5e-77 NP_001124400 (OMIM: 600660,608320) myocyte-specifi ( 429) 2790 260.4 7.3e-69 XP_011519889 (OMIM: 600660,608320) PREDICTED: myoc ( 429) 2790 260.4 7.3e-69 XP_011519888 (OMIM: 600660,608320) PREDICTED: myoc ( 437) 2764 258.1 3.6e-68 NP_001124399 (OMIM: 600660,608320) myocyte-specifi ( 437) 2764 258.1 3.6e-68 XP_016877684 (OMIM: 600660,608320) PREDICTED: myoc ( 431) 2578 241.7 3.2e-63 XP_016877690 (OMIM: 600660,608320) PREDICTED: myoc ( 375) 2480 233.0 1.2e-60 XP_016877689 (OMIM: 600660,608320) PREDICTED: myoc ( 375) 2480 233.0 1.2e-60 XP_016877688 (OMIM: 600660,608320) PREDICTED: myoc ( 379) 2480 233.0 1.2e-60 XP_016877687 (OMIM: 600660,608320) PREDICTED: myoc ( 383) 2454 230.7 5.8e-60 XP_016877686 (OMIM: 600660,608320) PREDICTED: myoc ( 383) 2454 230.7 5.8e-60 XP_016877685 (OMIM: 600660,608320) PREDICTED: myoc ( 387) 2454 230.7 5.8e-60 XP_011519887 (OMIM: 600660,608320) PREDICTED: myoc ( 443) 2454 230.7 6.5e-60 XP_016877679 (OMIM: 600660,608320) PREDICTED: myoc ( 507) 2454 230.8 7.2e-60 XP_016877680 (OMIM: 600660,608320) PREDICTED: myoc ( 507) 2454 230.8 7.2e-60 XP_011519884 (OMIM: 600660,608320) PREDICTED: myoc ( 507) 2454 230.8 7.2e-60 XP_011519883 (OMIM: 600660,608320) PREDICTED: myoc ( 507) 2454 230.8 7.2e-60 XP_011519874 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519880 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519873 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519875 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519879 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519881 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_011519878 (OMIM: 600660,608320) PREDICTED: myoc ( 511) 2454 230.8 7.3e-60 XP_016877691 (OMIM: 600660,608320) PREDICTED: myoc ( 366) 2384 224.5 4.1e-58 XP_011519892 (OMIM: 600660,608320) PREDICTED: myoc ( 307) 1686 162.8 1.3e-39 XP_016856803 (OMIM: 600663) PREDICTED: myocyte-spe ( 514) 1506 147.0 1.2e-34 NP_001258558 (OMIM: 600663) myocyte-specific enhan ( 514) 1506 147.0 1.2e-34 XP_016856804 (OMIM: 600663) PREDICTED: myocyte-spe ( 514) 1506 147.0 1.2e-34 XP_006711396 (OMIM: 600663) PREDICTED: myocyte-spe ( 514) 1506 147.0 1.2e-34 XP_016877693 (OMIM: 600660,608320) PREDICTED: myoc ( 257) 1484 144.9 2.7e-34 XP_005245227 (OMIM: 600663) PREDICTED: myocyte-spe ( 521) 1492 145.8 2.9e-34 XP_011507871 (OMIM: 600663) PREDICTED: myocyte-spe ( 521) 1492 145.8 2.9e-34 NP_005911 (OMIM: 600663) myocyte-specific enhancer ( 521) 1492 145.8 2.9e-34 XP_005245226 (OMIM: 600663) PREDICTED: myocyte-spe ( 521) 1492 145.8 2.9e-34 XP_006711393 (OMIM: 600663) PREDICTED: myocyte-spe ( 521) 1492 145.8 2.9e-34 XP_006711397 (OMIM: 600663) PREDICTED: myocyte-spe ( 513) 1437 140.9 8.2e-33 XP_006711395 (OMIM: 600663) PREDICTED: myocyte-spe ( 520) 1423 139.7 2e-32 NP_001180276 (OMIM: 600662,613443) myocyte-specifi ( 483) 1286 127.6 8.1e-29 XP_006714688 (OMIM: 600662,613443) PREDICTED: myoc ( 483) 1286 127.6 8.1e-29 XP_016877692 (OMIM: 600660,608320) PREDICTED: myoc ( 259) 1272 126.1 1.2e-28 >>NP_001124398 (OMIM: 600660,608320) myocyte-specific en (497 aa) initn: 3341 init1: 3341 opt: 3341 Z-score: 1619.5 bits: 309.2 E(85289): 1.8e-83 Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 497 aa overlap (1-497:1-497) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE 430 440 450 460 470 480 490 pF1KB3 DRESPSVKRMRMDAWVT ::::::::::::::::: NP_001 DRESPSVKRMRMDAWVT 490 >>NP_001165365 (OMIM: 600660,608320) myocyte-specific en (497 aa) initn: 3341 init1: 3341 opt: 3341 Z-score: 1619.5 bits: 309.2 E(85289): 1.8e-83 Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 497 aa overlap (1-497:1-497) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE 430 440 450 460 470 480 490 pF1KB3 DRESPSVKRMRMDAWVT ::::::::::::::::: NP_001 DRESPSVKRMRMDAWVT 490 >>XP_005254972 (OMIM: 600660,608320) PREDICTED: myocyte- (497 aa) initn: 3341 init1: 3341 opt: 3341 Z-score: 1619.5 bits: 309.2 E(85289): 1.8e-83 Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 497 aa overlap (1-497:1-497) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE 430 440 450 460 470 480 490 pF1KB3 DRESPSVKRMRMDAWVT ::::::::::::::::: XP_005 DRESPSVKRMRMDAWVT 490 >>XP_011519885 (OMIM: 600660,608320) PREDICTED: myocyte- (505 aa) initn: 2401 init1: 1908 opt: 3315 Z-score: 1607.0 bits: 306.9 E(85289): 9e-83 Smith-Waterman score: 3315; 98.4% identity (98.4% similar) in 505 aa overlap (1-497:1-505) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPL--------NTQRIS :::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_011 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIV 430 440 450 460 470 480 480 490 pF1KB3 LGRPPNTEDRESPSVKRMRMDAWVT ::::::::::::::::::::::::: XP_011 LGRPPNTEDRESPSVKRMRMDAWVT 490 500 >>NP_001306135 (OMIM: 600660,608320) myocyte-specific en (505 aa) initn: 2401 init1: 1908 opt: 3315 Z-score: 1607.0 bits: 306.9 E(85289): 9e-83 Smith-Waterman score: 3315; 98.4% identity (98.4% similar) in 505 aa overlap (1-497:1-505) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGAT 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPL--------NTQRIS :::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_001 GANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIV 430 440 450 460 470 480 480 490 pF1KB3 LGRPPNTEDRESPSVKRMRMDAWVT ::::::::::::::::::::::::: NP_001 LGRPPNTEDRESPSVKRMRMDAWVT 490 500 >>NP_005578 (OMIM: 600660,608320) myocyte-specific enhan (499 aa) initn: 3131 init1: 2480 opt: 3129 Z-score: 1518.2 bits: 290.4 E(85289): 7.9e-78 Smith-Waterman score: 3129; 93.8% identity (96.8% similar) in 499 aa overlap (1-497:1-499) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE ::::::::::::::::::::::::::.: :: ::.::: : . .: .:....:.:: NP_005 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DSDFIFK--RGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML . : ... . :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN 430 440 450 460 470 480 480 490 pF1KB3 TEDRESPSVKRMRMDAWVT ::::::::::::::::::: NP_005 TEDRESPSVKRMRMDAWVT 490 >>XP_016877682 (OMIM: 600660,608320) PREDICTED: myocyte- (499 aa) initn: 3131 init1: 2480 opt: 3129 Z-score: 1518.2 bits: 290.4 E(85289): 7.9e-78 Smith-Waterman score: 3129; 93.8% identity (96.8% similar) in 499 aa overlap (1-497:1-499) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE ::::::::::::::::::::::::::.: :: ::.::: : . .: .:....:.:: XP_016 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DSDFIFK--RGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML . : ... . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN 430 440 450 460 470 480 480 490 pF1KB3 TEDRESPSVKRMRMDAWVT ::::::::::::::::::: XP_016 TEDRESPSVKRMRMDAWVT 490 >>XP_016877683 (OMIM: 600660,608320) PREDICTED: myocyte- (499 aa) initn: 3131 init1: 2480 opt: 3129 Z-score: 1518.2 bits: 290.4 E(85289): 7.9e-78 Smith-Waterman score: 3129; 93.8% identity (96.8% similar) in 499 aa overlap (1-497:1-499) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE ::::::::::::::::::::::::::.: :: ::.::: : . .: .:....:.:: XP_016 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DSDFIFK--RGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML . : ... . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN 430 440 450 460 470 480 480 490 pF1KB3 TEDRESPSVKRMRMDAWVT ::::::::::::::::::: XP_016 TEDRESPSVKRMRMDAWVT 490 >>XP_016877681 (OMIM: 600660,608320) PREDICTED: myocyte- (503 aa) initn: 3131 init1: 2480 opt: 3119 Z-score: 1513.4 bits: 289.5 E(85289): 1.5e-77 Smith-Waterman score: 3119; 93.0% identity (95.8% similar) in 503 aa overlap (1-497:1-503) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE ::::::::::::::::::::::::::.: :: ::.::: : . .: .:....:.:: XP_016 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DSDFIFKRGP------PGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTD . : ... :::::::::::::::::::::::::::::::::::::::::::: XP_016 EFDNMMRNHKIAVSTKPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 SSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 NLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 QATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 SAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLG 430 440 450 460 470 480 480 490 pF1KB3 RPPNTEDRESPSVKRMRMDAWVT ::::::::::::::::::::::: XP_016 RPPNTEDRESPSVKRMRMDAWVT 490 500 >>XP_005254971 (OMIM: 600660,608320) PREDICTED: myocyte- (503 aa) initn: 3131 init1: 2480 opt: 3119 Z-score: 1513.4 bits: 289.5 E(85289): 1.5e-77 Smith-Waterman score: 3119; 93.0% identity (95.8% similar) in 503 aa overlap (1-497:1-503) 10 20 30 40 50 60 pF1KB3 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNE ::::::::::::::::::::::::::.: :: ::.::: : . .: .:....:.:: XP_005 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DSDFIFKRGP------PGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTD . : ... :::::::::::::::::::::::::::::::::::::::::::: XP_005 EFDNMMRNHKIAVSTKPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 SSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 NLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 QATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 SAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLG 430 440 450 460 470 480 480 490 pF1KB3 RPPNTEDRESPSVKRMRMDAWVT ::::::::::::::::::::::: XP_005 RPPNTEDRESPSVKRMRMDAWVT 490 500 497 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:21:23 2016 done: Thu Nov 3 13:21:25 2016 Total Scan time: 11.160 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]