FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3480, 316 aa 1>>>pF1KB3480 316 - 316 aa - 316 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6315+/-0.000361; mu= 15.1766+/- 0.022 mean_var=122.2967+/-24.927, 0's: 0 Z-trim(116.0): 173 B-trim: 36 in 2/57 Lambda= 0.115976 statistics sampled from 26605 (26799) to 26605 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.314), width: 16 Scan time: 7.900 The best scores are: opt bits E(85289) NP_067674 (OMIM: 146790,152700,611162) low affinit ( 316) 2117 365.4 8.8e-101 XP_016856152 (OMIM: 146790,152700,611162) PREDICTE ( 368) 2107 363.8 3.1e-100 NP_001129691 (OMIM: 146790,152700,611162) low affi ( 317) 2105 363.4 3.6e-100 XP_011507589 (OMIM: 146790,152700,611162) PREDICTE ( 369) 2095 361.8 1.3e-99 XP_016856154 (OMIM: 146790,152700,611162) PREDICTE ( 353) 2088 360.6 2.7e-99 XP_016856153 (OMIM: 146790,152700,611162) PREDICTE ( 353) 2088 360.6 2.7e-99 XP_011507592 (OMIM: 146790,152700,611162) PREDICTE ( 317) 2086 360.2 3.2e-99 NP_963857 (OMIM: 188030,612169) low affinity immun ( 323) 1789 310.5 3e-84 XP_011507593 (OMIM: 146790,152700,611162) PREDICTE ( 261) 1636 284.8 1.3e-76 XP_016856157 (OMIM: 146790,152700,611162) PREDICTE ( 275) 1403 245.8 7.4e-65 XP_016856156 (OMIM: 146790,152700,611162) PREDICTE ( 276) 1391 243.8 3e-64 XP_016856155 (OMIM: 146790,152700,611162) PREDICTE ( 328) 1391 243.9 3.3e-64 XP_016856161 (OMIM: 152700,604590,611162) PREDICTE ( 291) 1361 238.8 1e-62 NP_001002274 (OMIM: 152700,604590,611162) low affi ( 291) 1361 238.8 1e-62 NP_001002273 (OMIM: 152700,604590,611162) low affi ( 290) 1354 237.7 2.3e-62 XP_016856160 (OMIM: 152700,604590,611162) PREDICTE ( 310) 1336 234.7 1.9e-61 NP_003992 (OMIM: 152700,604590,611162) low affinit ( 310) 1336 234.7 1.9e-61 XP_016856158 (OMIM: 152700,604590,611162) PREDICTE ( 324) 1336 234.7 2e-61 NP_001177757 (OMIM: 152700,604590,611162) low affi ( 303) 1329 233.5 4.2e-61 NP_001002275 (OMIM: 152700,604590,611162) low affi ( 309) 1329 233.5 4.3e-61 XP_016856159 (OMIM: 152700,604590,611162) PREDICTE ( 323) 1329 233.5 4.4e-61 XP_011507594 (OMIM: 152700,604590,611162) PREDICTE ( 234) 1160 205.1 1.2e-52 NP_001257964 (OMIM: 610665) low affinity immunoglo ( 268) 641 118.3 1.7e-26 NP_001231682 (OMIM: 610665) low affinity immunoglo ( 269) 633 117.0 4.4e-26 NP_000561 (OMIM: 610665) low affinity immunoglobul ( 233) 626 115.7 9.1e-26 NP_001121064 (OMIM: 146740,615707) low affinity im ( 358) 625 115.8 1.3e-25 NP_001121068 (OMIM: 146740,615707) low affinity im ( 253) 618 114.4 2.4e-25 NP_000560 (OMIM: 146740,615707) low affinity immun ( 359) 617 114.4 3.4e-25 NP_001316049 (OMIM: 146740,615707) low affinity im ( 254) 610 113.1 6.1e-25 NP_001121065 (OMIM: 146740,615707) low affinity im ( 254) 610 113.1 6.1e-25 NP_001121067 (OMIM: 146740,615707) low affinity im ( 254) 610 113.1 6.1e-25 NP_001257965 (OMIM: 610665) low affinity immunoglo ( 216) 595 110.5 3.1e-24 NP_000557 (OMIM: 146760) high affinity immunoglobu ( 374) 565 105.8 1.5e-22 NP_001017986 (OMIM: 601502) high affinity immunogl ( 280) 559 104.6 2.4e-22 XP_005245014 (OMIM: 146760) PREDICTED: high affini ( 375) 555 104.1 4.7e-22 NP_001231839 (OMIM: 601502) high affinity immunogl ( 224) 549 102.8 6.7e-22 XP_016856150 (OMIM: 601502) PREDICTED: high affini ( 281) 548 102.8 8.7e-22 NP_001992 (OMIM: 147140) high affinity immunoglobu ( 257) 456 87.3 3.5e-17 NP_001275758 (OMIM: 609251) Fc receptor-like B iso ( 318) 425 82.3 1.5e-15 NP_001275760 (OMIM: 609251) Fc receptor-like B iso ( 275) 421 81.5 2.1e-15 NP_001002901 (OMIM: 609251) Fc receptor-like B iso ( 426) 421 81.7 2.8e-15 NP_001307170 (OMIM: 609251) Fc receptor-like B iso ( 426) 421 81.7 2.8e-15 NP_001275759 (OMIM: 609251) Fc receptor-like B iso ( 311) 407 79.2 1.2e-14 NP_001275761 (OMIM: 609251) Fc receptor-like B iso ( 268) 403 78.5 1.7e-14 NP_001316051 (OMIM: 146740,615707) low affinity im ( 273) 349 69.5 9e-12 XP_011508335 (OMIM: 605877) PREDICTED: Fc receptor ( 844) 349 70.0 1.9e-11 XP_011508333 (OMIM: 605877) PREDICTED: Fc receptor ( 884) 349 70.1 1.9e-11 XP_011508334 (OMIM: 605877) PREDICTED: Fc receptor ( 884) 349 70.1 1.9e-11 NP_112571 (OMIM: 605877) Fc receptor-like protein ( 977) 349 70.1 2.1e-11 NP_001182317 (OMIM: 605877) Fc receptor-like prote ( 998) 349 70.1 2.1e-11 >>NP_067674 (OMIM: 146790,152700,611162) low affinity im (316 aa) initn: 2117 init1: 2117 opt: 2117 Z-score: 1930.3 bits: 365.4 E(85289): 8.8e-101 Smith-Waterman score: 2117; 99.7% identity (100.0% similar) in 316 aa overlap (1-316:1-316) 10 20 30 40 50 60 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHSH :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: NP_067 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 SGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK 250 260 270 280 290 300 310 pF1KB3 NIYLTLPPNDHVNSNN :::::::::::::::: NP_067 NIYLTLPPNDHVNSNN 310 >>XP_016856152 (OMIM: 146790,152700,611162) PREDICTED: l (368 aa) initn: 2139 init1: 2107 opt: 2107 Z-score: 1920.5 bits: 363.8 E(85289): 3.1e-100 Smith-Waterman score: 2107; 99.4% identity (100.0% similar) in 315 aa overlap (1-315:1-315) 10 20 30 40 50 60 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHSH :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_016 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK 250 260 270 280 290 300 310 pF1KB3 NIYLTLPPNDHVNSNN :::::::::::::.: XP_016 NIYLTLPPNDHVNTNKAFTLFWNTSCQKGKLQVNCQWRLLTSCTAIFPVQLPEGCDLLRE 310 320 330 340 350 360 >>NP_001129691 (OMIM: 146790,152700,611162) low affinity (317 aa) initn: 1908 init1: 1908 opt: 2105 Z-score: 1919.4 bits: 363.4 E(85289): 3.6e-100 Smith-Waterman score: 2105; 99.4% identity (99.7% similar) in 317 aa overlap (1-316:1-317) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD 250 260 270 280 290 300 300 310 pF1KB3 KNIYLTLPPNDHVNSNN ::::::::::::::::: NP_001 KNIYLTLPPNDHVNSNN 310 >>XP_011507589 (OMIM: 146790,152700,611162) PREDICTED: l (369 aa) initn: 2156 init1: 1897 opt: 2095 Z-score: 1909.6 bits: 361.8 E(85289): 1.3e-99 Smith-Waterman score: 2095; 99.1% identity (99.7% similar) in 316 aa overlap (1-315:1-316) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD 250 260 270 280 290 300 300 310 pF1KB3 KNIYLTLPPNDHVNSNN ::::::::::::::.: XP_011 KNIYLTLPPNDHVNTNKAFTLFWNTSCQKGKLQVNCQWRLLTSCTAIFPVQLPEGCDLLR 310 320 330 340 350 360 >>XP_016856154 (OMIM: 146790,152700,611162) PREDICTED: l (353 aa) initn: 2149 init1: 1890 opt: 2088 Z-score: 1903.5 bits: 360.6 E(85289): 2.7e-99 Smith-Waterman score: 2088; 99.0% identity (99.7% similar) in 315 aa overlap (1-314:1-315) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD 250 260 270 280 290 300 300 310 pF1KB3 KNIYLTLPPNDHVNSNN ::::::::::::::. XP_016 KNIYLTLPPNDHVNTEIRTPADLNGMFWIEESGKWPQFTKSQPDKNQCDFTAQ 310 320 330 340 350 >>XP_016856153 (OMIM: 146790,152700,611162) PREDICTED: l (353 aa) initn: 2149 init1: 1890 opt: 2088 Z-score: 1903.5 bits: 360.6 E(85289): 2.7e-99 Smith-Waterman score: 2088; 99.0% identity (99.7% similar) in 315 aa overlap (1-314:1-315) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD 250 260 270 280 290 300 300 310 pF1KB3 KNIYLTLPPNDHVNSNN ::::::::::::::. XP_016 KNIYLTLPPNDHVNTEIRTPADLNGMFWIEESGKWPQFTKSQPDKNQCDFTAQ 310 320 330 340 350 >>XP_011507592 (OMIM: 146790,152700,611162) PREDICTED: l (317 aa) initn: 1889 init1: 1889 opt: 2086 Z-score: 1902.3 bits: 360.2 E(85289): 3.2e-99 Smith-Waterman score: 2086; 99.4% identity (99.7% similar) in 314 aa overlap (1-313:1-314) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD 250 260 270 280 290 300 300 310 pF1KB3 KNIYLTLPPNDHVNSNN :::::::::::::: XP_011 KNIYLTLPPNDHVNRLY 310 >>NP_963857 (OMIM: 188030,612169) low affinity immunoglo (323 aa) initn: 1185 init1: 1151 opt: 1789 Z-score: 1633.6 bits: 310.5 E(85289): 3e-84 Smith-Waterman score: 1789; 85.5% identity (91.8% similar) in 318 aa overlap (1-316:10-323) 10 20 30 40 pF1KB3 MTMETQMSQNVCPRNLW--LLQPLTVLLLLASADSQAAPPKAVLKLEPPWI .. :.. .. :. : .: .::.: : . :::::::::::: :: NP_963 MGILSFLPVLATESDWADCKSPQP-WGHMLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWI 10 20 30 40 50 50 60 70 80 90 100 pF1KB3 NVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTS ::::::::::::.:..::::::: :::::::::::::::::::::::::::::::::::: NP_963 NVLQEDSVTLTCRGTHSPESDSIPWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 LSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDP :::::::::::::::::::::::::::::.::::::::::::::::::::::.:::: :: NP_963 LSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 TFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAA .::::::::::::::::::::::::.::::::::::.:: ::::::::::: . :::: NP_963 NFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPS---SSPMGIIVAVVTGIAVAA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 IVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMT ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: NP_963 IVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQPEETNNDYETADGGYMT 240 250 260 270 280 290 290 300 310 pF1KB3 LNPRAPTDDDKNIYLTLPPNDHVNSNN ::::::::::::::::::::::::::: NP_963 LNPRAPTDDDKNIYLTLPPNDHVNSNN 300 310 320 >>XP_011507593 (OMIM: 146790,152700,611162) PREDICTED: l (261 aa) initn: 1697 init1: 1438 opt: 1636 Z-score: 1496.3 bits: 284.8 E(85289): 1.3e-76 Smith-Waterman score: 1636; 98.4% identity (99.2% similar) in 251 aa overlap (1-250:1-251) 10 20 30 40 50 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAA-PPKAVLKLEPPWINVLQEDSVTL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHS ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 SEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 CRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD ::::::::. : XP_011 CRKKRISATWTSNDCHQKETT 250 260 >>XP_016856157 (OMIM: 146790,152700,611162) PREDICTED: l (275 aa) initn: 1435 init1: 1403 opt: 1403 Z-score: 1285.4 bits: 245.8 E(85289): 7.4e-65 Smith-Waterman score: 1783; 86.7% identity (87.0% similar) in 316 aa overlap (1-316:1-275) 10 20 30 40 50 60 pF1KB3 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHSH :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_016 EWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYC ::::::::::::::::::::::::: XP_016 SGDYHCTGNIGYTLFSSKPVTITVQ----------------------------------- 190 200 250 260 270 280 290 300 pF1KB3 RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ------ANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK 210 220 230 240 250 310 pF1KB3 NIYLTLPPNDHVNSNN :::::::::::::::: XP_016 NIYLTLPPNDHVNSNN 260 270 316 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:09:28 2016 done: Sat Nov 5 05:09:29 2016 Total Scan time: 7.900 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]