FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3481, 782 aa 1>>>pF1KB3481 782 - 782 aa - 782 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9461+/-0.000401; mu= 18.3292+/- 0.025 mean_var=93.3259+/-18.307, 0's: 0 Z-trim(113.5): 24 B-trim: 0 in 0/49 Lambda= 0.132762 statistics sampled from 22873 (22889) to 22873 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.268), width: 16 Scan time: 10.990 The best scores are: opt bits E(85289) NP_000113 (OMIM: 133510,610651,616390) TFIIH basal ( 782) 5187 1004.3 0 XP_011509096 (OMIM: 133510,610651,616390) PREDICTE ( 788) 5165 1000.1 0 NP_001290345 (OMIM: 133510,610651,616390) TFIIH ba ( 718) 4752 921.0 0 NP_001290347 (OMIM: 133510,610651,616390) TFIIH ba ( 718) 4752 921.0 0 XP_016859072 (OMIM: 133510,610651,616390) PREDICTE ( 630) 4161 807.8 0 XP_011509097 (OMIM: 133510,610651,616390) PREDICTE ( 636) 4139 803.6 0 >>NP_000113 (OMIM: 133510,610651,616390) TFIIH basal tra (782 aa) initn: 5187 init1: 5187 opt: 5187 Z-score: 5369.5 bits: 1004.3 E(85289): 0 Smith-Waterman score: 5187; 100.0% identity (100.0% similar) in 782 aa overlap (1-782:1-782) 10 20 30 40 50 60 pF1KB3 MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 HPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRND 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 WEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 NFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 FRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 KINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 DLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRF 730 740 750 760 770 780 pF1KB3 RK :: NP_000 RK >>XP_011509096 (OMIM: 133510,610651,616390) PREDICTED: T (788 aa) initn: 3723 init1: 3723 opt: 5165 Z-score: 5346.7 bits: 1000.1 E(85289): 0 Smith-Waterman score: 5165; 99.2% identity (99.2% similar) in 788 aa overlap (1-782:1-788) 10 20 30 40 50 60 pF1KB3 MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESC 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 HPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSA------ISKTAESSGGPSTSR ::::::::::::::::::::::::::::::::::::::: ::::::::::::::: XP_011 HPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAHLPLSQISKTAESSGGPSTSR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 VTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 YDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 CTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 HTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVRED 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 DKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 TMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQ 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 NFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 YNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQ 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 KVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVH 730 740 750 760 770 780 780 pF1KB3 PLFKRFRK :::::::: XP_011 PLFKRFRK >>NP_001290345 (OMIM: 133510,610651,616390) TFIIH basal (718 aa) initn: 4752 init1: 4752 opt: 4752 Z-score: 4919.8 bits: 921.0 E(85289): 0 Smith-Waterman score: 4752; 100.0% identity (100.0% similar) in 718 aa overlap (65-782:1-718) 40 50 60 70 80 90 pF1KB3 QEAVPSAAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYK :::::::::::::::::::::::::::::: NP_001 MPLKDDHTSRPLWVAPDGHIFLEAFSPVYK 10 20 30 100 110 120 130 140 150 pF1KB3 YAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 FIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETF 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 TSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 EMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRAR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 SGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB3 DAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB3 LTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPM 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB3 SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIR 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB3 LNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRR 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB3 QEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLA 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB3 GMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGAD 640 650 660 670 680 690 760 770 780 pF1KB3 DTVYMEYHSSRSKAPSKHVHPLFKRFRK :::::::::::::::::::::::::::: NP_001 DTVYMEYHSSRSKAPSKHVHPLFKRFRK 700 710 >>NP_001290347 (OMIM: 133510,610651,616390) TFIIH basal (718 aa) initn: 4752 init1: 4752 opt: 4752 Z-score: 4919.8 bits: 921.0 E(85289): 0 Smith-Waterman score: 4752; 100.0% identity (100.0% similar) in 718 aa overlap (65-782:1-718) 40 50 60 70 80 90 pF1KB3 QEAVPSAAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYK :::::::::::::::::::::::::::::: NP_001 MPLKDDHTSRPLWVAPDGHIFLEAFSPVYK 10 20 30 100 110 120 130 140 150 pF1KB3 YAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 FIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETF 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 TSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 EMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRAR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 SGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB3 DAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB3 LTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPM 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB3 SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIR 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB3 LNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRR 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB3 QEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLA 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB3 GMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGAD 640 650 660 670 680 690 760 770 780 pF1KB3 DTVYMEYHSSRSKAPSKHVHPLFKRFRK :::::::::::::::::::::::::::: NP_001 DTVYMEYHSSRSKAPSKHVHPLFKRFRK 700 710 >>XP_016859072 (OMIM: 133510,610651,616390) PREDICTED: T (630 aa) initn: 4161 init1: 4161 opt: 4161 Z-score: 4308.8 bits: 807.8 E(85289): 0 Smith-Waterman score: 4161; 100.0% identity (100.0% similar) in 630 aa overlap (153-782:1-630) 130 140 150 160 170 180 pF1KB3 LYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHP :::::::::::::::::::::::::::::: XP_016 MQFIKLCTVSYGKVKLVLKHNRYFVESCHP 10 20 30 190 200 210 220 230 240 pF1KB3 DVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQGKS 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB3 DIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSV 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB3 NPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCL 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB3 VLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWE 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB3 AERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNF 280 290 300 310 320 330 490 500 510 520 530 540 pF1KB3 LIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFR 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB3 ACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKI 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB3 NTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSL 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB3 VSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAATDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAATDL 520 530 540 550 560 570 730 740 750 760 770 780 pF1KB3 DAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRFRK 580 590 600 610 620 630 >>XP_011509097 (OMIM: 133510,610651,616390) PREDICTED: T (636 aa) initn: 3723 init1: 3723 opt: 4139 Z-score: 4286.0 bits: 803.6 E(85289): 0 Smith-Waterman score: 4139; 99.1% identity (99.1% similar) in 636 aa overlap (153-782:1-636) 130 140 150 160 170 180 pF1KB3 LYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHP :::::::::::::::::::::::::::::: XP_011 MQFIKLCTVSYGKVKLVLKHNRYFVESCHP 10 20 30 190 200 210 220 230 pF1KB3 DVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSA------ISKTAESSGGPSTSRVT ::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_011 DVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAHLPLSQISKTAESSGGPSTSRVT 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB3 DPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYD 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB3 FRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACT 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB3 VRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHT 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB3 TKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDK 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB3 IVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTM 340 350 360 370 380 390 540 550 560 570 580 590 pF1KB3 NPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNF 400 410 420 430 440 450 600 610 620 630 640 650 pF1KB3 KHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYN 460 470 480 490 500 510 660 670 680 690 700 710 pF1KB3 AFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKV 520 530 540 550 560 570 720 730 740 750 760 770 pF1KB3 LAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPL 580 590 600 610 620 630 780 pF1KB3 FKRFRK :::::: XP_011 FKRFRK 782 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:23:31 2016 done: Thu Nov 3 13:23:32 2016 Total Scan time: 10.990 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]