FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3482, 733 aa 1>>>pF1KB3482 733 - 733 aa - 733 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7753+/-0.000399; mu= 0.3329+/- 0.025 mean_var=199.3515+/-39.984, 0's: 0 Z-trim(118.8): 21 B-trim: 17 in 1/55 Lambda= 0.090837 statistics sampled from 32005 (32026) to 32005 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.375), width: 16 Scan time: 9.470 The best scores are: opt bits E(85289) NP_005522 (OMIM: 147586) gamma-interferon-inducibl ( 729) 4720 631.3 4e-180 XP_016856639 (OMIM: 147586) PREDICTED: gamma-inter ( 520) 3254 439.2 2e-122 XP_005245184 (OMIM: 147586) PREDICTED: gamma-inter ( 789) 3254 439.2 2.9e-122 XP_016856638 (OMIM: 147586) PREDICTED: gamma-inter ( 677) 2868 388.6 4.3e-107 XP_006711353 (OMIM: 147586) PREDICTED: gamma-inter ( 677) 2868 388.6 4.3e-107 NP_001193496 (OMIM: 147586) gamma-interferon-induc ( 729) 2777 376.7 1.8e-103 NP_945146 (OMIM: 612677) pyrin and HIN domain-cont ( 483) 1981 272.3 3.2e-72 NP_945148 (OMIM: 612677) pyrin and HIN domain-cont ( 452) 1966 270.4 1.2e-71 NP_689714 (OMIM: 612677) pyrin and HIN domain-cont ( 492) 1530 213.2 2e-54 XP_011507544 (OMIM: 612677) PREDICTED: pyrin and H ( 492) 1530 213.2 2e-54 NP_945147 (OMIM: 612677) pyrin and HIN domain-cont ( 461) 1515 211.3 7.3e-54 XP_011507545 (OMIM: 612677) PREDICTED: pyrin and H ( 457) 1510 210.6 1.1e-53 XP_016855952 (OMIM: 612677) PREDICTED: pyrin and H ( 462) 1510 210.6 1.2e-53 NP_002423 (OMIM: 159553) myeloid cell nuclear diff ( 407) 1285 181.1 7.8e-45 XP_005244987 (OMIM: 612677) PREDICTED: pyrin and H ( 245) 537 83.0 1.6e-15 XP_016858337 (OMIM: 604578) PREDICTED: interferon- ( 343) 529 82.0 4.5e-15 NP_004824 (OMIM: 604578) interferon-inducible prot ( 343) 529 82.0 4.5e-15 XP_005245673 (OMIM: 604578) PREDICTED: interferon- ( 238) 516 80.2 1.1e-14 >>NP_005522 (OMIM: 147586) gamma-interferon-inducible pr (729 aa) initn: 4720 init1: 4720 opt: 4720 Z-score: 3354.7 bits: 631.3 E(85289): 4e-180 Smith-Waterman score: 4720; 99.7% identity (99.7% similar) in 729 aa overlap (5-733:1-729) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: NP_005 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 PAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB3 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB3 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN 660 670 680 690 700 710 730 pF1KB3 PDSSMETSPDFFF ::::::::::::: NP_005 PDSSMETSPDFFF 720 >>XP_016856639 (OMIM: 147586) PREDICTED: gamma-interfero (520 aa) initn: 3254 init1: 3254 opt: 3254 Z-score: 2318.8 bits: 439.2 E(85289): 2e-122 Smith-Waterman score: 3254; 99.6% identity (99.6% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: XP_016 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE ::::::::::::::::::::::: XP_016 PAESHPHTPQMPPSTPSSSFLTTESFCCSESSGSKADSST 490 500 510 520 >>XP_005245184 (OMIM: 147586) PREDICTED: gamma-interfero (789 aa) initn: 3254 init1: 3254 opt: 3254 Z-score: 2315.9 bits: 439.2 E(85289): 2.9e-122 Smith-Waterman score: 4460; 92.4% identity (92.4% similar) in 765 aa overlap (1-709:1-765) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: XP_005 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG 430 440 450 460 470 480 490 500 pF1KB3 PAESHPHTPQMPPSTPSSSFLTT------------------------------------- ::::::::::::::::::::::: XP_005 PAESHPHTPQMPPSTPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAES 490 500 510 520 530 540 510 520 530 540 pF1KB3 -------------------LKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ ::::::::::::::::::::::::::::::::::::::::: XP_005 HPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB3 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB3 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV 670 680 690 700 710 720 670 680 690 700 710 720 pF1KB3 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS ::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS 730 740 750 760 770 780 730 pF1KB3 METSPDFFF XP_005 METSPDFFF >>XP_016856638 (OMIM: 147586) PREDICTED: gamma-interfero (677 aa) initn: 2868 init1: 2868 opt: 2868 Z-score: 2043.6 bits: 388.6 E(85289): 4.3e-107 Smith-Waterman score: 4235; 92.1% identity (92.1% similar) in 733 aa overlap (1-733:1-677) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: XP_016 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG ::::::::::::::::::::::::::: XP_016 ASTTFPESHLRTPQMPPTTPSSSFFTK--------------------------------- 430 440 490 500 510 520 530 540 pF1KB3 PAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE ::::::::::::::::::::::::::::::::::::: XP_016 -----------------------LKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE 450 460 470 480 550 560 570 580 590 600 pF1KB3 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN 610 620 630 640 650 660 730 pF1KB3 PDSSMETSPDFFF ::::::::::::: XP_016 PDSSMETSPDFFF 670 >>XP_006711353 (OMIM: 147586) PREDICTED: gamma-interfero (677 aa) initn: 2868 init1: 2868 opt: 2868 Z-score: 2043.6 bits: 388.6 E(85289): 4.3e-107 Smith-Waterman score: 4235; 92.1% identity (92.1% similar) in 733 aa overlap (1-733:1-677) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: XP_006 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG ::::::::::::::::::::::::::: XP_006 ASTTFPESHLRTPQMPPTTPSSSFFTK--------------------------------- 430 440 490 500 510 520 530 540 pF1KB3 PAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE ::::::::::::::::::::::::::::::::::::: XP_006 -----------------------LKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYE 450 460 470 480 550 560 570 580 590 600 pF1KB3 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTG 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN 610 620 630 640 650 660 730 pF1KB3 PDSSMETSPDFFF ::::::::::::: XP_006 PDSSMETSPDFFF 670 >>NP_001193496 (OMIM: 147586) gamma-interferon-inducible (729 aa) initn: 2598 init1: 2598 opt: 2777 Z-score: 1978.6 bits: 376.7 E(85289): 1.8e-103 Smith-Waterman score: 4115; 85.5% identity (85.5% similar) in 785 aa overlap (5-733:1-729) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP ::::::::::: NP_001 TEGAEATPGAQ------------------------------------------------- 120 190 200 210 220 230 240 pF1KB3 PNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------NPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQ 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB3 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIIN 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB3 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPC 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB3 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPSE :::::::::::::::::::::::::::::::::::::::::::::::::::: ::: ::: NP_001 EEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSE 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB3 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIG 370 380 390 400 410 420 490 500 pF1KB3 PAESHPHTPQMPPSTPSSSFLTT------------------------------------- ::::::::::::::::::::::: NP_001 PAESHPHTPQMPPSTPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAES 430 440 450 460 470 480 510 520 530 540 pF1KB3 -------------------LKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ ::::::::::::::::::::::::::::::::::::::::: NP_001 HPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS 670 680 690 700 710 720 730 pF1KB3 METSPDFFF ::::::::: NP_001 METSPDFFF >>NP_945146 (OMIM: 612677) pyrin and HIN domain-containi (483 aa) initn: 1495 init1: 1495 opt: 1981 Z-score: 1417.7 bits: 272.3 E(85289): 3.2e-72 Smith-Waterman score: 1981; 65.2% identity (83.7% similar) in 486 aa overlap (5-489:1-483) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :...::.::::::::::::::::.:::::::::::: ::.:::::::::::::::: NP_945 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRK-KEVDATSPAPSTSSTV :::::::::..:..:::: :::::::.::::::: :.: : ::: ..:: . :. . NP_945 PGDAGLGKLIEFFKEIPTLGDLAETLKREKLKVKGIIPSKKTKQKEVYPATPACTPSNRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSA ..::: : : ::::: ..:..: : ::.:.:::.: :::. :::::::: :.:: :: NP_945 TAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 PPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVAT :::.::::. : .:. ..: .:.... :.:. ::..:: :.::. : :.. :::::::: NP_945 PPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVAT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 QTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKII ::::::::::: .::.:: :.:::::.: . .::::::: :.::::::.::::::. :: NP_945 QTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEVPKDII 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 NRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIP :::. ::.:::::.:: ::::.:::: : ::.::::::::: :.: ::: :.::::: NP_945 RRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGECHNIP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 CEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPS ::.::::.::::::::...::::.:::::::::.:.:: :..: .:: ::::::: :.:: NP_945 CEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQHPKPS 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 EASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSI :::::.:::::.:::::::::::: ::::.: . ... ..: : .: ..: NP_945 EASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFRIT---SPTVAPPLSSD 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 GPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY .. :: .: NP_945 TSTNRHPAVP 480 >>NP_945148 (OMIM: 612677) pyrin and HIN domain-containi (452 aa) initn: 1987 init1: 1484 opt: 1966 Z-score: 1407.5 bits: 270.4 E(85289): 1.2e-71 Smith-Waterman score: 1966; 69.0% identity (86.6% similar) in 448 aa overlap (5-451:1-448) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :...::.::::::::::::::::.:::::::::::: ::.:::::::::::::::: NP_945 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRK-KEVDATSPAPSTSSTV :::::::::..:..:::: :::::::.::::::: :.: : ::: ..:: . :. . NP_945 PGDAGLGKLIEFFKEIPTLGDLAETLKREKLKVKGIIPSKKTKQKEVYPATPACTPSNRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSA ..::: : : ::::: ..:..: : ::.:.:::.: :::. :::::::: :.:: :: NP_945 TAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 PPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVAT :::.::::. : .:. ..: .:.... :.:. ::..:: :.::. : :.. :::::::: NP_945 PPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVAT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 QTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKII ::::::::::: .::.:: :.:::::.: . .::::::: :.::::::.::::::. :: NP_945 QTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEVPKDII 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 NRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIP :::. ::.:::::.:: ::::.:::: : ::.::::::::: :.: ::: :.::::: NP_945 RRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGECHNIP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 CEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQSQLPNPS ::.::::.::::::::...::::.:::::::::.:.:: :..: .:: ::::::: :.:: NP_945 CEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQHPKPS 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 EASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSI :::::.:::::.:::::::::::: ::: ..: NP_945 EASTTLPESHLKTPQMPPTTPSSSSFTKVTKDKDIK 420 430 440 450 480 490 500 510 520 530 pF1KB3 GPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY >>NP_689714 (OMIM: 612677) pyrin and HIN domain-containi (492 aa) initn: 1950 init1: 1495 opt: 1530 Z-score: 1098.1 bits: 213.2 E(85289): 2e-54 Smith-Waterman score: 1953; 64.0% identity (82.2% similar) in 495 aa overlap (5-489:1-492) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :...::.::::::::::::::::.:::::::::::: ::.:::::::::::::::: NP_689 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKV---------KGPALSRKRK-KEVDATS :::::::::..:..:::: :::::::.::::: :: :.: : ::: .. NP_689 PGDAGLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPAT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 PAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRS :: . :. . ..::: : : ::::: ..:..: : ::.:.:::.: :::. ::::::: NP_689 PACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 PSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKK : :.:: :::::.::::. : .:. ..: .:.... :.:. ::..:: :.::. : :.. NP_689 PPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 IMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQ ::::::::::::::::::: .::.:: :.:::::.: . .::::::: :.::::::.: NP_689 RMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 TFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVV :::::. :: :::. ::.:::::.:: ::::.:::: : ::.::::::::: :.: :: NP_689 TFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 GTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQ : :.:::::::.::::.::::::::...::::.:::::::::.:.:: :..: .:: ::: NP_689 GKGECHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 EQSQLPNPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSH :::: :.:::::::.:::::.:::::::::::: ::::.: . ... ..: : NP_689 EQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFRIT---SP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 FPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMV .: ..: .. :: .: NP_689 TVAPPLSSDTSTNRHPAVP 480 490 >>XP_011507544 (OMIM: 612677) PREDICTED: pyrin and HIN d (492 aa) initn: 1950 init1: 1495 opt: 1530 Z-score: 1098.1 bits: 213.2 E(85289): 2e-54 Smith-Waterman score: 1953; 64.0% identity (82.2% similar) in 495 aa overlap (5-489:1-492) 10 20 30 40 50 60 pF1KB3 MSVKMGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKF :...::.::::::::::::::::.:::::::::::: ::.:::::::::::::::: XP_011 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKF 10 20 30 40 50 70 80 90 100 110 pF1KB3 RGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKV---------KGPALSRKRK-KEVDATS :::::::::..:..:::: :::::::.::::: :: :.: : ::: .. XP_011 PGDAGLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPAT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 PAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRS :: . :. . ..::: : : ::::: ..:..: : ::.:.:::.: :::. ::::::: XP_011 PACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 PSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKK : :.:: :::::.::::. : .:. ..: .:.... :.:. ::..:: :.::. : :.. XP_011 PPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 IMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQ ::::::::::::::::::: .::.:: :.:::::.: . .::::::: :.::::::.: XP_011 RMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 TFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVV :::::. :: :::. ::.:::::.:: ::::.:::: : ::.::::::::: :.: :: XP_011 TFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 GTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQ : :.:::::::.::::.::::::::...::::.:::::::::.:.:: :..: .:: ::: XP_011 GKGECHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 EQSQLPNPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSH :::: :.:::::::.:::::.:::::::::::: ::::.: . ... ..: : XP_011 EQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFRIT---SP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 FPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMV .: ..: .. :: .: XP_011 TVAPPLSSDTSTNRHPAVP 480 490 733 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:01:00 2016 done: Thu Nov 3 21:01:02 2016 Total Scan time: 9.470 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]