Result of FASTA (ccds) for
pF1KB3486
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3486, 368 aa
1>>>pF1KB3486 368 - 368 aa - 368 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9552+/-0.00106; mu= 5.8875+/- 0.063
mean_var=195.6197+/-39.828, 0's: 0 Z-trim(110.6): 130 B-trim: 15 in 2/51
Lambda= 0.091700
statistics sampled from 11587 (11729) to 11587 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.36), width: 16
Scan time: 2.230
The best scores are: opt bits E(32554)
CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 368) 2426 333.3 2e-91
CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 320) 1727 240.8 1.3e-63
CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 304) 1515 212.7 3.4e-55
CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 ( 352) 1390 196.2 3.6e-50
CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 ( 347) 1262 179.3 4.4e-45
CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 ( 355) 1184 169.0 5.8e-42
CCDS710.1 SH3GLB1 gene_id:51100|Hs108|chr1 ( 365) 422 68.2 1.3e-11
>>CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 (368 aa)
initn: 2426 init1: 2426 opt: 2426 Z-score: 1754.7 bits: 333.3 E(32554): 2e-91
Smith-Waterman score: 2426; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368)
10 20 30 40 50 60
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
310 320 330 340 350 360
pF1KB3 EVLVPLPQ
::::::::
CCDS32 EVLVPLPQ
>>CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 (320 aa)
initn: 1727 init1: 1727 opt: 1727 Z-score: 1255.7 bits: 240.8 E(32554): 1.3e-63
Smith-Waterman score: 2002; 87.0% identity (87.0% similar) in 368 aa overlap (1-368:1-320)
10 20 30 40 50 60
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
:: ::::::::::
CCDS56 NP------------------------------------------------GDALLDAGES
70
130 140 150 160 170 180
pF1KB3 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB3 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB3 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB3 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
260 270 280 290 300 310
pF1KB3 EVLVPLPQ
::::::::
CCDS56 EVLVPLPQ
320
>>CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 (304 aa)
initn: 1515 init1: 1515 opt: 1515 Z-score: 1104.4 bits: 212.7 E(32554): 3.4e-55
Smith-Waterman score: 1860; 82.6% identity (82.6% similar) in 368 aa overlap (1-368:1-304)
10 20 30 40 50 60
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
::::::::::::::::::::
CCDS59 NPASRAKLTMLNTVSKIRGQ----------------------------------------
70 80
130 140 150 160 170 180
pF1KB3 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
::::::::::::::::::::::::::::::::::::
CCDS59 ------------------------NLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
90 100 110
190 200 210 220 230 240
pF1KB3 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB3 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPS
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB3 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 RSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV
240 250 260 270 280 290
pF1KB3 EVLVPLPQ
::::::::
CCDS59 EVLVPLPQ
300
>>CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 (352 aa)
initn: 1721 init1: 1349 opt: 1390 Z-score: 1014.2 bits: 196.2 E(32554): 3.6e-50
Smith-Waterman score: 1720; 71.1% identity (87.0% similar) in 370 aa overlap (1-368:1-352)
10 20 30 40 50 60
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
::::::::::.::.: :::::::::::::::::::::.::::::.:: :....:::::::
CCDS64 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
::::::::.:.::.:::::: :.:::::.:.::.: :.. :.::: . ::: :: ..::.
CCDS64 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
:..:.::::::::::::::::::::: .:::.::::::::::::::::::::::::::::
CCDS64 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
::::::::::.::::.::.:: :::: ::::::::::::.:::.::.::::::.... .:
CCDS64 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
190 200 210 220 230 240
250 260 270 280 290
pF1KB3 KRRMREASSRPKREYKPKPREP--FDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRT
..:.:.:::.:.:::.:::: : :. : :::. : .::
CCDS64 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPK----------------
250 260 270 280
300 310 320 330 340 350
pF1KB3 PSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLS
:: . .::: :.:::::::::.:::::.:::.:::::::::::::::: :.:::::..
CCDS64 PSGVQ--MDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPIN
290 300 310 320 330 340
360
pF1KB3 YVEVLVPLPQ
:::.:: ::.
CCDS64 YVEILVALPH
350
>>CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 (347 aa)
initn: 1640 init1: 1262 opt: 1262 Z-score: 922.8 bits: 179.3 E(32554): 4.4e-45
Smith-Waterman score: 1606; 66.5% identity (85.1% similar) in 370 aa overlap (1-368:1-347)
10 20 30 40 50 60
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
::::::::::.::::: :::..:::::::::.: .::.:.:::.:.:.:.:..: :::::
CCDS10 MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
::: :::: :::::::::::::. ::::.:::::.::...::::: .:.::.::...:::
CCDS10 NPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
:: .:::::::::.:::.:::::: : .:::::: ::::::::::::.:::::: :::::
CCDS10 MKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
::.:::.::::::::.:: :: :.::.:.::::::.....: ::::::...::.:: ::
CCDS10 EEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKL
190 200 210 220 230 240
250 260 270 280 290
pF1KB3 KRRMREASSRPKREYKPKP--REPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRT
. :. ::: :.:::::.: : .: :: ....: ... . :
CCDS10 QMRISAASSVPRREYKPRPVKRSSSEL------NG---------VSTTSVVKTTGSNI--
250 260 270 280
300 310 320 330 340 350
pF1KB3 PSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLS
:.::: :..::::::::.:::::.:::.:::::::::::::::. :.:::::..
CCDS10 ------PMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPIN
290 300 310 320 330
360
pF1KB3 YVEVLVPLPQ
::::.:::::
CCDS10 YVEVIVPLPQ
340
>>CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 (355 aa)
initn: 1562 init1: 1184 opt: 1184 Z-score: 866.9 bits: 169.0 E(32554): 5.8e-42
Smith-Waterman score: 1528; 64.5% identity (84.6% similar) in 358 aa overlap (11-368:19-355)
10 20 30 40 50
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLA
. ..:: :::..:::::::::.: .::.:.:::.:.:.:.:.
CCDS73 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 RTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGD
.: :::::::: :::: :::::::::::::. ::::.:::::.::...::::: .:.::.
CCDS73 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 ALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKK
::...::::: .:::::::::.:::.:::::: : .:::::: ::::::::::::.::::
CCDS73 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 KRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQI
:: :::::::.:::.::::::::.:: :: :.::.:.::::::.....: ::::::...:
CCDS73 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 LDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSS
:.:: ::. :. ::: :.:::::.: . . :: ....: ...
CCDS73 LQELQSKLQMRISAASSVPRREYKPRPVKR----SSSELNG---------VSTTSVVKTT
250 260 270 280
300 310 320 330 340 350
pF1KB3 DKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQS
. : :.::: :..::::::::.:::::.:::.:::::::::::::::. :.:
CCDS73 GSNI--------PMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGES
290 300 310 320 330
360
pF1KB3 GFFPLSYVEVLVPLPQ
::::..::::.:::::
CCDS73 GFFPINYVEVIVPLPQ
340 350
>>CCDS710.1 SH3GLB1 gene_id:51100|Hs108|chr1 (365 aa)
initn: 322 init1: 193 opt: 422 Z-score: 321.9 bits: 68.2 E(32554): 1.3e-11
Smith-Waterman score: 432; 27.3% identity (57.9% similar) in 366 aa overlap (12-363:21-364)
10 20 30 40 50
pF1KB3 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVL
.: :.. ::.: :: :.:: .... .:.. :. . ...
CCDS71 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 ARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFG
.: ::::: .: . . . ... : :. .. :::. :: : :.: . .:
CCDS71 KQTEVLLQPNPNARIEEFVYEKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYG
70 80 90 100 110
120 130 140 150 160 170
pF1KB3 DALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYK
.::. ::..::.. . : ::. ::.:. : : : : .. : :...:::.:
CCDS71 NALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAA
120 130 140 150 160 170
180 190 200 210 220
pF1KB3 KKRQGKIP--------DEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQL
: : : ..::: . .:... :... .... : ... :. .:.::.
CCDS71 KTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQM
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB3 DYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKI
:. : : . .: ..: .: :. .: :.. .:.. .. :.
CCDS71 TYYAQCYQYMLDLQKQL-------GSFPS-NY---------LSNNNQTSVTPVPSVLPNA
240 250 260 270
290 300 310 320 330
pF1KB3 AASSSFRSSDKPIRTPSRSMPPLDQPS----CKALYDFEPENDGELGFHEGDVITLTNQI
.::.. :.. . : .. : . : ..:::.. :. ::.. .:::. . .
CCDS71 IGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVV
280 290 300 310 320 330
340 350 360
pF1KB3 --DENWYEGMLDGQSGFFPLSYVEVLVPLPQ
: .: : .:.: :..:.:.:
CCDS71 GMDSDWLMGERGNQKGKVPITYLELLN
340 350 360
368 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:13:22 2016 done: Fri Nov 4 23:13:22 2016
Total Scan time: 2.230 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]