FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3487, 664 aa 1>>>pF1KB3487 664 - 664 aa - 664 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9244+/-0.000937; mu= 15.7298+/- 0.056 mean_var=67.7163+/-13.658, 0's: 0 Z-trim(104.6): 28 B-trim: 4 in 1/49 Lambda= 0.155857 statistics sampled from 7971 (7979) to 7971 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.245), width: 16 Scan time: 3.660 The best scores are: opt bits E(32554) CCDS3853.1 SDHA gene_id:6389|Hs108|chr5 ( 664) 4485 1017.9 0 CCDS82985.1 SDHA gene_id:6389|Hs108|chr5 ( 583) 3501 796.6 0 CCDS77992.1 SDHA gene_id:6389|Hs108|chr5 ( 616) 3474 790.6 0 >>CCDS3853.1 SDHA gene_id:6389|Hs108|chr5 (664 aa) initn: 4485 init1: 4485 opt: 4485 Z-score: 5445.3 bits: 1017.9 E(32554): 0 Smith-Waterman score: 4485; 99.8% identity (100.0% similar) in 664 aa overlap (1-664:1-664) 10 20 30 40 50 60 pF1KB3 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 IDEYDYSKPIQGQQKKPFEEHWRKHTLSFVDVGTGKVTLEYRPVIDKTLNEADCATVPPA ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: CCDS38 IDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPA 610 620 630 640 650 660 pF1KB3 IRSY :::: CCDS38 IRSY >>CCDS82985.1 SDHA gene_id:6389|Hs108|chr5 (583 aa) initn: 3501 init1: 3501 opt: 3501 Z-score: 4250.5 bits: 796.6 E(32554): 0 Smith-Waterman score: 3777; 87.7% identity (87.8% similar) in 664 aa overlap (1-664:1-583) 10 20 30 40 50 60 pF1KB3 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS ::::::::::::::::::::::::::::::::::::: CCDS82 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQK----------------------- 490 500 510 550 560 570 580 590 600 pF1KB3 KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR :: CCDS82 ----------------------------------------------------------VR 610 620 630 640 650 660 pF1KB3 IDEYDYSKPIQGQQKKPFEEHWRKHTLSFVDVGTGKVTLEYRPVIDKTLNEADCATVPPA ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: CCDS82 IDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPA 520 530 540 550 560 570 pF1KB3 IRSY :::: CCDS82 IRSY 580 >>CCDS77992.1 SDHA gene_id:6389|Hs108|chr5 (616 aa) initn: 3474 init1: 3474 opt: 3474 Z-score: 4217.3 bits: 790.6 E(32554): 0 Smith-Waterman score: 4034; 92.6% identity (92.8% similar) in 664 aa overlap (1-664:1-616) 10 20 30 40 50 60 pF1KB3 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR :::::::::::::::::::::::::::::::::::::::::::: CCDS77 EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQ---------------- 70 80 90 100 130 140 150 160 170 180 pF1KB3 WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF :::::::::::::::::::::::::::: CCDS77 --------------------------------LENYGMPFSRTEDGKIYQRAFGGQSLKF 110 120 130 190 200 210 220 230 240 pF1KB3 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB3 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB3 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR 500 510 520 530 540 550 610 620 630 640 650 660 pF1KB3 IDEYDYSKPIQGQQKKPFEEHWRKHTLSFVDVGTGKVTLEYRPVIDKTLNEADCATVPPA ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: CCDS77 IDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPA 560 570 580 590 600 610 pF1KB3 IRSY :::: CCDS77 IRSY 664 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:06:54 2016 done: Sat Nov 5 07:06:55 2016 Total Scan time: 3.660 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]