FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3490, 337 aa 1>>>pF1KB3490 337 - 337 aa - 337 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8936+/-0.000407; mu= 12.7792+/- 0.025 mean_var=77.2630+/-15.680, 0's: 0 Z-trim(111.7): 87 B-trim: 53 in 1/54 Lambda= 0.145911 statistics sampled from 20347 (20438) to 20347 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.24), width: 16 Scan time: 6.000 The best scores are: opt bits E(85289) NP_001193730 (OMIM: 600407) replication factor C s ( 337) 2168 466.2 4.6e-131 NP_031396 (OMIM: 600407) replication factor C subu ( 340) 2147 461.7 9.9e-130 XP_011536945 (OMIM: 600407) PREDICTED: replication ( 340) 2147 461.7 9.9e-130 XP_011536947 (OMIM: 600407) PREDICTED: replication ( 340) 2147 461.7 9.9e-130 NP_853556 (OMIM: 600407) replication factor C subu ( 319) 2001 431.0 1.7e-120 XP_016875268 (OMIM: 600407) PREDICTED: replication ( 304) 1849 399.0 6.9e-111 NP_001123584 (OMIM: 600407) replication factor C s ( 255) 1584 343.2 3.7e-94 NP_002907 (OMIM: 102577) replication factor C subu ( 363) 741 165.8 1.3e-40 NP_853551 (OMIM: 102577) replication factor C subu ( 363) 741 165.8 1.3e-40 NP_852136 (OMIM: 600404) replication factor C subu ( 354) 735 164.5 3.1e-40 NP_001265720 (OMIM: 600404) replication factor C s ( 253) 536 122.5 9.3e-28 XP_016867981 (OMIM: 600404) PREDICTED: replication ( 253) 536 122.5 9.3e-28 NP_001265721 (OMIM: 600404) replication factor C s ( 251) 493 113.5 4.9e-25 NP_001265722 (OMIM: 600404) replication factor C s ( 219) 394 92.6 8.2e-19 NP_002905 (OMIM: 600404) replication factor C subu ( 320) 396 93.1 8.5e-19 XP_006716143 (OMIM: 600404) PREDICTED: replication ( 217) 385 90.7 3e-18 XP_016867982 (OMIM: 600404) PREDICTED: replication ( 217) 385 90.7 3e-18 NP_002906 (OMIM: 600405) replication factor C subu ( 356) 247 61.8 2.6e-09 XP_016876172 (OMIM: 600405) PREDICTED: replication ( 291) 235 59.2 1.2e-08 XP_016876171 (OMIM: 600405) PREDICTED: replication ( 293) 235 59.2 1.3e-08 XP_016876170 (OMIM: 600405) PREDICTED: replication ( 297) 235 59.2 1.3e-08 XP_011533476 (OMIM: 600405) PREDICTED: replication ( 297) 235 59.2 1.3e-08 XP_011533477 (OMIM: 600405) PREDICTED: replication ( 297) 235 59.2 1.3e-08 XP_011533475 (OMIM: 600405) PREDICTED: replication ( 298) 235 59.2 1.3e-08 NP_853536 (OMIM: 600405) replication factor C subu ( 305) 235 59.2 1.3e-08 XP_016876169 (OMIM: 600405) PREDICTED: replication ( 313) 235 59.2 1.3e-08 XP_011533474 (OMIM: 600405) PREDICTED: replication ( 343) 235 59.2 1.4e-08 XP_005249289 (OMIM: 608196) PREDICTED: ATPase WRNI ( 419) 172 46.0 0.00017 XP_016866549 (OMIM: 608196) PREDICTED: ATPase WRNI ( 438) 172 46.0 0.00017 NP_569079 (OMIM: 608196) ATPase WRNIP1 isoform 2 [ ( 640) 174 46.5 0.00018 NP_064520 (OMIM: 608196) ATPase WRNIP1 isoform 1 [ ( 665) 172 46.1 0.00025 >>NP_001193730 (OMIM: 600407) replication factor C subun (337 aa) initn: 2168 init1: 2168 opt: 2168 Z-score: 2474.0 bits: 466.2 E(85289): 4.6e-131 Smith-Waterman score: 2168; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HPLKSDIANILDWMLNQDFTTAYRKLKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPLKSDIANILDWMLNQDFTTAYRKLKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLT 250 260 270 280 290 300 310 320 330 pF1KB3 KMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA ::::::::::::::::::::::::::::::::::::: NP_001 KMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 310 320 330 >>NP_031396 (OMIM: 600407) replication factor C subunit (340 aa) initn: 1737 init1: 1737 opt: 2147 Z-score: 2450.1 bits: 461.7 E(85289): 9.9e-130 Smith-Waterman score: 2147; 98.8% identity (99.1% similar) in 340 aa overlap (1-337:1-340) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 HPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHRVDFPSSVRIH :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::: NP_031 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 250 260 270 280 290 300 300 310 320 330 pF1KB3 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA :::::::::::::::::::::::::::::::::::::::: NP_031 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 310 320 330 340 >>XP_011536945 (OMIM: 600407) PREDICTED: replication fac (340 aa) initn: 1737 init1: 1737 opt: 2147 Z-score: 2450.1 bits: 461.7 E(85289): 9.9e-130 Smith-Waterman score: 2147; 98.8% identity (99.1% similar) in 340 aa overlap (1-337:1-340) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 HPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHRVDFPSSVRIH :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::: XP_011 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 250 260 270 280 290 300 300 310 320 330 pF1KB3 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA :::::::::::::::::::::::::::::::::::::::: XP_011 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 310 320 330 340 >>XP_011536947 (OMIM: 600407) PREDICTED: replication fac (340 aa) initn: 1737 init1: 1737 opt: 2147 Z-score: 2450.1 bits: 461.7 E(85289): 9.9e-130 Smith-Waterman score: 2147; 98.8% identity (99.1% similar) in 340 aa overlap (1-337:1-340) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 HPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHRVDFPSSVRIH :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::: XP_011 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 250 260 270 280 290 300 300 310 320 330 pF1KB3 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA :::::::::::::::::::::::::::::::::::::::: XP_011 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 310 320 330 340 >>NP_853556 (OMIM: 600407) replication factor C subunit (319 aa) initn: 1591 init1: 1591 opt: 2001 Z-score: 2284.4 bits: 431.0 E(85289): 1.7e-120 Smith-Waterman score: 2001; 98.7% identity (99.1% similar) in 318 aa overlap (23-337:2-319) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::: NP_853 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_853 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 160 170 180 190 200 210 250 260 270 280 290 pF1KB3 HPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHRVDFPSSVRIH :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::: NP_853 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 220 230 240 250 260 270 300 310 320 330 pF1KB3 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA :::::::::::::::::::::::::::::::::::::::: NP_853 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 280 290 300 310 >>XP_016875268 (OMIM: 600407) PREDICTED: replication fac (304 aa) initn: 1737 init1: 1737 opt: 1849 Z-score: 2111.8 bits: 399.0 E(85289): 6.9e-111 Smith-Waterman score: 1849; 95.3% identity (97.3% similar) in 301 aa overlap (1-296:1-301) 10 20 30 40 50 60 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 HPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHR--VDFPSSVR :::::::::::::::::::::::: .:::::::::::::::::::::: . .: . . XP_016 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRGNLHYPPAEK 250 260 270 280 290 300 300 310 320 330 pF1KB3 IHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA . XP_016 LWRR >>NP_001123584 (OMIM: 600407) replication factor C subun (255 aa) initn: 1174 init1: 1174 opt: 1584 Z-score: 1811.5 bits: 343.2 E(85289): 3.7e-94 Smith-Waterman score: 1584; 98.4% identity (98.8% similar) in 255 aa overlap (86-337:1-255) 60 70 80 90 100 110 pF1KB3 LLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIF :::::::::::::::::::::::::::::: NP_001 MVLELNASDDRGIDIIRGPILSFASTRTIF 10 20 30 120 130 140 150 160 170 pF1KB3 KKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFG 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 PLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETV 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 YTCTGHPLKSDIANILDWMLNQDFTTAYR---KLKTLKGLALHDILTEIHLFVHRVDFPS ::::::::::::::::::::::::::::: .::::::::::::::::::::::::::: NP_001 YTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPS 160 170 180 190 200 210 300 310 320 330 pF1KB3 SVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA ::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 220 230 240 250 >>NP_002907 (OMIM: 102577) replication factor C subunit (363 aa) initn: 714 init1: 388 opt: 741 Z-score: 850.1 bits: 165.8 E(85289): 1.3e-40 Smith-Waterman score: 741; 40.0% identity (70.9% similar) in 320 aa overlap (16-324:34-353) 10 20 30 40 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQ : . .::::::::. .... ......... NP_002 FLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 KFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPI : .. ::.::.:::::::::::::: :..:. . : ::::::::.:::...: . NP_002 KSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKV 70 80 90 100 110 120 110 120 130 140 150 pF1KB3 LSFAS-----TRTIFKK--GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYL .::. .:. : ::.:::::::.::. :: ::::..:: ...:::::::::. NP_002 KNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 SKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALN :.:: : :::..::: ::. ... :: ....:.: ::..:. :: .: ::.:.:.. NP_002 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAIT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB3 ILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRKLKTL--KGLAL .::: : .. :: .::... .: : ... . .: .: : .: : NP_002 FLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB3 HDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIV ......: : . .. .. . . :.:... :. :..:..:: :: : NP_002 TQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC 310 320 330 340 350 360 pF1KB3 AEA >>NP_853551 (OMIM: 102577) replication factor C subunit (363 aa) initn: 714 init1: 388 opt: 741 Z-score: 850.1 bits: 165.8 E(85289): 1.3e-40 Smith-Waterman score: 741; 40.0% identity (70.9% similar) in 320 aa overlap (16-324:34-353) 10 20 30 40 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQ : . .::::::::. .... ......... NP_853 FLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 KFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPI : .. ::.::.:::::::::::::: :..:. . : ::::::::.:::...: . NP_853 KSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKV 70 80 90 100 110 120 110 120 130 140 150 pF1KB3 LSFAS-----TRTIFKK--GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYL .::. .:. : ::.:::::::.::. :: ::::..:: ...:::::::::. NP_853 KNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 SKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALN :.:: : :::..::: ::. ... :: ....:.: ::..:. :: .: ::.:.:.. NP_853 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAIT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB3 ILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRKLKTL--KGLAL .::: : .. :: .::... .: : ... . .: .: : .: : NP_853 FLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB3 HDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIV ......: : . .. .. . . :.:... :. :..:..:: :: : NP_853 TQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC 310 320 330 340 350 360 pF1KB3 AEA >>NP_852136 (OMIM: 600404) replication factor C subunit (354 aa) initn: 673 init1: 573 opt: 735 Z-score: 843.4 bits: 164.5 E(85289): 3.1e-40 Smith-Waterman score: 735; 37.0% identity (70.3% similar) in 316 aa overlap (12-324:28-342) 10 20 30 40 pF1KB3 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTI :... .::::::::: ::......: .: . NP_852 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 QKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGP . : : .:.... ::::::::..:: :. : . . .::::::.:::::..:. NP_852 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALL-GPALKDAMLELNASNDRGIDVVRNK 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 ILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIP : ::. .. . :: :..::::::.::. ::.::::..: ....::: : :: .::: NP_852 IKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 ALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQST .::::. .:. :: .. :: .:.:.:.: ..::..:.. ..::::.::: :::: NP_852 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQST 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 NMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRKLKTLK--GLALHDILTEI .:: .. :.:. .: . .... .: .. ::. : : : . .::. .: NP_852 FSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNI 240 250 260 270 280 290 290 300 310 320 330 pF1KB3 HLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA . .. ...... ... ..... :.: .:...:.: NP_852 FRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 300 310 320 330 340 350 337 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:31:53 2016 done: Fri Nov 4 02:31:54 2016 Total Scan time: 6.000 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]