Result of FASTA (omim) for
pF1KB3501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3501, 380 aa
1>>>pF1KB3501 380 - 380 aa - 380 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9245+/-0.000435; mu= 18.6294+/- 0.027
mean_var=64.8530+/-13.411, 0's: 0 Z-trim(110.0): 171 B-trim: 0 in 0/50
Lambda= 0.159261
statistics sampled from 18144 (18322) to 18144 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.215), width: 16
Scan time: 5.500
The best scores are: opt bits E(85289)
NP_056963 (OMIM: 609478) sia-alpha-2,3-Gal-beta-1, ( 380) 2567 599.0 6e-171
NP_001317345 (OMIM: 602546) alpha-2,8-sialyltransf ( 354) 817 196.9 6.2e-50
NP_006002 (OMIM: 602546) alpha-2,8-sialyltransfera ( 375) 817 196.9 6.5e-50
XP_016878131 (OMIM: 602546) PREDICTED: alpha-2,8-s ( 396) 817 196.9 6.8e-50
NP_005659 (OMIM: 602547) CMP-N-acetylneuraminate-p ( 359) 765 184.9 2.5e-46
XP_016871663 (OMIM: 610139) PREDICTED: alpha-2,8-s ( 368) 651 158.8 1.9e-38
NP_001004470 (OMIM: 610139) alpha-2,8-sialyltransf ( 398) 651 158.8 2.1e-38
NP_003025 (OMIM: 601123) alpha-N-acetylneuraminide ( 356) 599 146.8 7.4e-35
NP_001332890 (OMIM: 610139) alpha-2,8-sialyltransf ( 247) 588 144.2 3.2e-34
XP_005272135 (OMIM: 602547) PREDICTED: CMP-N-acety ( 282) 497 123.3 7e-28
XP_016881204 (OMIM: 607162) PREDICTED: alpha-2,8-s ( 302) 497 123.3 7.4e-28
NP_001294916 (OMIM: 607162) alpha-2,8-sialyltransf ( 345) 497 123.4 8.2e-28
NP_037437 (OMIM: 607162) alpha-2,8-sialyltransfera ( 376) 497 123.4 8.8e-28
NP_001294915 (OMIM: 607162) alpha-2,8-sialyltransf ( 412) 497 123.4 9.5e-28
XP_016881205 (OMIM: 607162) PREDICTED: alpha-2,8-s ( 228) 475 118.2 2e-26
NP_001291379 (OMIM: 601123) alpha-N-acetylneuramin ( 213) 375 95.2 1.5e-19
NP_778222 (OMIM: 602547) CMP-N-acetylneuraminate-p ( 168) 300 77.9 2e-14
XP_011541932 (OMIM: 602547) PREDICTED: CMP-N-acety ( 261) 293 76.4 8.5e-14
NP_112227 (OMIM: 610134) alpha-N-acetylgalactosami ( 336) 256 68.0 3.8e-11
NP_778204 (OMIM: 606378) alpha-N-acetyl-neuraminyl ( 302) 252 67.0 6.5e-11
XP_011516829 (OMIM: 606378) PREDICTED: alpha-N-ace ( 325) 252 67.0 6.9e-11
XP_016860690 (OMIM: 604402,609056) PREDICTED: lact ( 390) 232 62.5 1.9e-09
XP_016860688 (OMIM: 604402,609056) PREDICTED: lact ( 390) 232 62.5 1.9e-09
XP_016860689 (OMIM: 604402,609056) PREDICTED: lact ( 390) 232 62.5 1.9e-09
NP_001035902 (OMIM: 604402,609056) lactosylceramid ( 395) 232 62.5 2e-09
NP_003887 (OMIM: 604402,609056) lactosylceramide a ( 418) 232 62.5 2e-09
NP_001310297 (OMIM: 607156) type 2 lactosamine alp ( 331) 228 61.5 3.2e-09
NP_001258075 (OMIM: 607156) type 2 lactosamine alp ( 331) 228 61.5 3.2e-09
NP_001310294 (OMIM: 607156) type 2 lactosamine alp ( 331) 228 61.5 3.2e-09
NP_001310281 (OMIM: 607156) type 2 lactosamine alp ( 331) 228 61.5 3.2e-09
NP_006091 (OMIM: 607156) type 2 lactosamine alpha- ( 331) 228 61.5 3.2e-09
NP_001310296 (OMIM: 607156) type 2 lactosamine alp ( 354) 228 61.6 3.4e-09
NP_001258074 (OMIM: 607156) type 2 lactosamine alp ( 384) 228 61.6 3.6e-09
NP_001310288 (OMIM: 607156) type 2 lactosamine alp ( 223) 219 59.3 9.9e-09
NP_001310287 (OMIM: 607156) type 2 lactosamine alp ( 223) 219 59.3 9.9e-09
NP_001310289 (OMIM: 607156) type 2 lactosamine alp ( 245) 219 59.4 1.1e-08
NP_001258071 (OMIM: 607156) type 2 lactosamine alp ( 245) 219 59.4 1.1e-08
NP_001310295 (OMIM: 607156) type 2 lactosamine alp ( 245) 219 59.4 1.1e-08
XP_011516913 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 217 59.0 1.7e-08
XP_016870154 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 217 59.0 1.7e-08
NP_001273929 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 217 59.0 1.7e-08
NP_001273930 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 217 59.0 1.7e-08
NP_001273931 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 217 59.0 1.7e-08
XP_016870155 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 217 59.0 1.7e-08
XP_016870156 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 217 59.0 1.7e-08
NP_038471 (OMIM: 610135) alpha-N-acetylgalactosami ( 333) 217 59.0 1.9e-08
XP_011516912 (OMIM: 610135) PREDICTED: alpha-N-ace ( 333) 217 59.0 1.9e-08
NP_001135823 (OMIM: 608472) beta-galactoside alpha ( 529) 219 59.6 1.9e-08
XP_006712865 (OMIM: 608472) PREDICTED: beta-galact ( 529) 219 59.6 1.9e-08
NP_115917 (OMIM: 608472) beta-galactoside alpha-2, ( 529) 219 59.6 1.9e-08
>>NP_056963 (OMIM: 609478) sia-alpha-2,3-Gal-beta-1,4-Gl (380 aa)
initn: 2567 init1: 2567 opt: 2567 Z-score: 3190.1 bits: 599.0 E(85289): 6e-171
Smith-Waterman score: 2567; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KB3 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
310 320 330 340 350 360
370 380
pF1KB3 QLLYRMHGEGLTKLTLSHCA
::::::::::::::::::::
NP_056 QLLYRMHGEGLTKLTLSHCA
370 380
>>NP_001317345 (OMIM: 602546) alpha-2,8-sialyltransferas (354 aa)
initn: 716 init1: 410 opt: 817 Z-score: 1017.5 bits: 196.9 E(85289): 6.2e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:44-350)
40 50 60 70 80 90
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
:. : .: :. ...: :::. :.: :
NP_001 TLLVVFLIFADISEIEEEIGAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
. :..::. .:. :..:. :.... :...:: .. . ....:.:. ::: .::. :::
NP_001 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
80 90 100 110 120 130
160 170 180 190 200 210
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
.. ::.:::::.: .: :::::: .::.:::.::.. . :::: ::.:.:.:::....
NP_001 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
...:.. :.... :..:.:.:::::::. . . .. . .....: ...:. :.:
NP_001 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
200 210 220 230 240 250
280 290 300 310 320 330
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
. . :. : :: .... :: .::.::::::. .:..:.::::::: .: : .. . ::
NP_001 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
260 270 280 290 300
340 350 360 370 380
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
:::. .:.. : .: ::. : .: .: :::...:
NP_001 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
310 320 330 340 350
>>NP_006002 (OMIM: 602546) alpha-2,8-sialyltransferase 8 (375 aa)
initn: 716 init1: 410 opt: 817 Z-score: 1017.1 bits: 196.9 E(85289): 6.5e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:65-371)
40 50 60 70 80 90
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
:. : .: :. ...: :::. :.: :
NP_006 SGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
. :..::. .:. :..:. :.... :...:: .. . ....:.:. ::: .::. :::
NP_006 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
.. ::.:::::.: .: :::::: .::.:::.::.. . :::: ::.:.:.:::....
NP_006 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
...:.. :.... :..:.:.:::::::. . . .. . .....: ...:. :.:
NP_006 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
. . :. : :: .... :: .::.::::::. .:..:.::::::: .: : .. . ::
NP_006 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
280 290 300 310 320 330
340 350 360 370 380
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
:::. .:.. : .: ::. : .: .: :::...:
NP_006 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
340 350 360 370
>>XP_016878131 (OMIM: 602546) PREDICTED: alpha-2,8-sialy (396 aa)
initn: 716 init1: 410 opt: 817 Z-score: 1016.8 bits: 196.9 E(85289): 6.8e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:86-392)
40 50 60 70 80 90
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
:. : .: :. ...: :::. :.: :
XP_016 SGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
. :..::. .:. :..:. :.... :...:: .. . ....:.:. ::: .::. :::
XP_016 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
.. ::.:::::.: .: :::::: .::.:::.::.. . :::: ::.:.:.:::....
XP_016 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
...:.. :.... :..:.:.:::::::. . . .. . .....: ...:. :.:
XP_016 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
. . :. : :: .... :: .::.::::::. .:..:.::::::: .: : .. . ::
XP_016 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
300 310 320 330 340 350
340 350 360 370 380
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
:::. .:.. : .: ::. : .: .: :::...:
XP_016 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
360 370 380 390
>>NP_005659 (OMIM: 602547) CMP-N-acetylneuraminate-poly- (359 aa)
initn: 677 init1: 392 opt: 765 Z-score: 952.8 bits: 184.9 E(85289): 2.5e-46
Smith-Waterman score: 765; 39.3% identity (73.5% similar) in 298 aa overlap (83-379:64-356)
60 70 80 90 100 110
pF1KB3 YMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIK
.:.. ::.: . :. :..::. .:. .
NP_005 TQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAER
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 NFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILT
. :..:.: . :...:: ... ...::....::::.:::. :.... ::::::::::
NP_005 DVSVVKSSFKPGDVIHY-VLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 GSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFF
:.::.:::. .::.:::.::. : ::: :... :.:::.... .... . .::..:
NP_005 DSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 LSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNR-YWKN
:. :. ..::::::. . . .. . ... ...:::. :.:. . :. : :: .
NP_005 HRLSMLNDSVLWIPAFMVKGGEKHVEWVNALIL--KNKLKVRTAYPSLRLIHAVRGYWLT
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 KHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQ
... :: :::.::::::. .:.:::::::::: : : . . ::::: .. ..
NP_005 NKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKA-VKYHYYDDLKYRYFSN-A
280 290 300 310 320
360 370 380
pF1KB3 ESHQLPAEFQLLYRMHGEGLTKLTLSHCA
:..: ::. : .:..: ::: ..:
NP_005 SPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ
330 340 350
>>XP_016871663 (OMIM: 610139) PREDICTED: alpha-2,8-sialy (368 aa)
initn: 445 init1: 204 opt: 651 Z-score: 811.1 bits: 158.8 E(85289): 1.9e-38
Smith-Waterman score: 651; 35.8% identity (67.5% similar) in 302 aa overlap (82-379:79-365)
60 70 80 90 100 110
pF1KB3 MYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVI
..: : :: . . . : .. . :..
XP_016 AALRTLRSPATAVPRATNRYSENDYLQIITDIQSCP--WKRQAEEYANFRAKLASCCDAV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 KNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGIL
.:: ...:.. .: : :. :.: . :..:. ..: .:... :: ::::::.:::
XP_016 QNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 TGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNN
. : :: ::::::::::::. :: . ..::: ::::.:.::::. :.:: ....
XP_016 NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNL---KEKKA
170 180 190 200 210 220
240 250 260 270 280
pF1KB3 FFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYW
.:: .. :.. .::: :.... .. . . : ... :: . : . .. . .:
XP_016 LFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHP-KYLKDLALFW
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 KNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLP--YHYYDKKGTKFT
..: .. :::::... ..: .:....:::::::. .: ::.: .::::.: :
XP_016 RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDIPVSHHYYDNKLPK--
290 300 310 320 330
350 360 370 380
pF1KB3 TKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
. ::.: :.. . ..: .:. :: .:.:
XP_016 ---HGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
340 350 360
>>NP_001004470 (OMIM: 610139) alpha-2,8-sialyltransferas (398 aa)
initn: 445 init1: 204 opt: 651 Z-score: 810.6 bits: 158.8 E(85289): 2.1e-38
Smith-Waterman score: 651; 35.8% identity (67.5% similar) in 302 aa overlap (82-379:109-395)
60 70 80 90 100 110
pF1KB3 MYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVI
..: : :: . . . : .. . :..
NP_001 EKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCP--WKRQAEEYANFRAKLASCCDAV
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 KNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGIL
.:: ...:.. .: : :. :.: . :..:. ..: .:... :: ::::::.:::
NP_001 QNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 TGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNN
. : :: ::::::::::::. :: . ..::: ::::.:.::::. :.:: ....
NP_001 NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNL---KEKKA
200 210 220 230 240 250
240 250 260 270 280
pF1KB3 FFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYW
.:: .. :.. .::: :.... .. . . : ... :: . : . .. . .:
NP_001 LFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHP-KYLKDLALFW
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB3 KNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLP--YHYYDKKGTKFT
..: .. :::::... ..: .:....:::::::. .: ::.: .::::.: :
NP_001 RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDIPVSHHYYDNKLPK--
320 330 340 350 360
350 360 370 380
pF1KB3 TKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
. ::.: :.. . ..: .:. :: .:.:
NP_001 ---HGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
370 380 390
>>NP_003025 (OMIM: 601123) alpha-N-acetylneuraminide alp (356 aa)
initn: 420 init1: 155 opt: 599 Z-score: 746.7 bits: 146.8 E(85289): 7.4e-35
Smith-Waterman score: 599; 31.4% identity (66.0% similar) in 315 aa overlap (67-379:44-347)
40 50 60 70 80 90
pF1KB3 NIFTTPKYASPGAPRMYMFHAGFRSQFALKFLDPSF-VPITNSLTQELQEKPSKWKFNRT
.. : . .: . ..: . .. . :. :.:
NP_003 GAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQGVLQQGTAWRRNQT
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB3 AFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIM
: :... . : . :..:: . .:. : :: . : :.:.:. ::.:...:..
NP_003 AARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYD-GEFLYSFTIDNSTYSLFPQATPFQ
80 90 100 110 120 130
160 170 180 190 200 210
pF1KB3 NKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAP-TEAFQRDVGRKTNLTTFNPSI
. ::::::.::: : ::..::...::.:::. : . . .::: :..:.: ::::
NP_003 -LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSI
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB3 LEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQ
... ..::: .:..: ..: . . ...::: ..:.. . . . . .. :
NP_003 IRQRFQNLL--WSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVL
200 210 220 230 240
280 290 300 310 320 330
pF1KB3 LAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
.: : :... ....::.. . ::::::... . : ..:::. .::::::. . . .. .
NP_003 FANP-NFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMH-EQPI
250 260 270 280 290 300
340 350 360 370 380
pF1KB3 PYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
.::::. . .. : .: :: :. .: : .. :. :
NP_003 SHHYYDN-----VLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDTSLQPTS
310 320 330 340 350
>>NP_001332890 (OMIM: 610139) alpha-2,8-sialyltransferas (247 aa)
initn: 445 init1: 204 opt: 588 Z-score: 735.3 bits: 144.2 E(85289): 3.2e-34
Smith-Waterman score: 588; 38.1% identity (68.5% similar) in 257 aa overlap (127-379:1-244)
100 110 120 130 140 150
pF1KB3 FLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMN
: :. :.: . :..:. ..: .:...
NP_001 MSYEVESKKEI-PIKKNIFHMFPVSQPFVD
10 20
160 170 180 190 200 210
pF1KB3 KHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSIL
:: ::::::.:::. : :: ::::::::::::. :: . ..::: ::::.:.::::.
NP_001 YPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSII
30 40 50 60 70 80
220 230 240 250 260 270
pF1KB3 EKYYNNLLTIQDRNNFFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQ
:.:: .... .:: .. :.. .::: :.... .. . . : ... ::
NP_001 TLKYGNL---KEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVL
90 100 110 120 130 140
280 290 300 310 320 330
pF1KB3 LAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
. : . .. . .:..: .. :::::... ..: .:....:::::::. .: ::.
NP_001 FFHP-KYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDI
150 160 170 180 190 200
340 350 360 370 380
pF1KB3 P--YHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
: .::::.: : ::.: :.. . ..: .:. :: .:.:
NP_001 PVSHHYYDNKLPKHGF-----HQMPKEYSQILQLHMKGILKLQFSKCEVA
210 220 230 240
>>XP_005272135 (OMIM: 602547) PREDICTED: CMP-N-acetylneu (282 aa)
initn: 480 init1: 392 opt: 497 Z-score: 621.5 bits: 123.3 E(85289): 7e-28
Smith-Waterman score: 497; 35.8% identity (74.9% similar) in 215 aa overlap (83-297:64-275)
60 70 80 90 100 110
pF1KB3 YMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIK
.:.. ::.: . :. :..::. .:. .
XP_005 TQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAER
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 NFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILT
. :..:.: . :...:: ... ...::....::::.:::. :.... ::::::::::
XP_005 DVSVVKSSFKPGDVIHY-VLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 GSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFF
:.::.:::. .::.:::.::. : ::: :... :.:::.... .... . .::..:
XP_005 DSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 LSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNK
:. :. ..::::::. . . .. . ...... :::. :.:. . :. : . ..
XP_005 HRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNK--LKVRTAYPSLRLIHAVRGFCEN
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 HLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQE
:. :
XP_005 FLDFKEDLNNSN
280
380 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:32:51 2016 done: Fri Nov 4 02:32:52 2016
Total Scan time: 5.500 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]