FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3502, 243 aa 1>>>pF1KB3502 243 - 243 aa - 243 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2979+/-0.000933; mu= 10.6409+/- 0.056 mean_var=95.5559+/-18.696, 0's: 0 Z-trim(107.4): 15 B-trim: 0 in 0/50 Lambda= 0.131204 statistics sampled from 9573 (9579) to 9573 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.294), width: 16 Scan time: 2.040 The best scores are: opt bits E(32554) CCDS33498.1 VAPB gene_id:9217|Hs108|chr20 ( 243) 1570 307.1 7e-84 CCDS11848.2 VAPA gene_id:9218|Hs108|chr18 ( 249) 1014 201.8 3.5e-52 CCDS11847.2 VAPA gene_id:9218|Hs108|chr18 ( 294) 761 154.0 1e-37 CCDS56198.1 VAPB gene_id:9217|Hs108|chr20 ( 99) 467 98.1 2.4e-21 >>CCDS33498.1 VAPB gene_id:9217|Hs108|chr20 (243 aa) initn: 1570 init1: 1570 opt: 1570 Z-score: 1619.4 bits: 307.1 E(32554): 7e-84 Smith-Waterman score: 1570; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243) 10 20 30 40 50 60 pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK 190 200 210 220 230 240 pF1KB3 IAL ::: CCDS33 IAL >>CCDS11848.2 VAPA gene_id:9218|Hs108|chr18 (249 aa) initn: 990 init1: 800 opt: 1014 Z-score: 1050.4 bits: 201.8 E(32554): 3.5e-52 Smith-Waterman score: 1014; 62.9% identity (85.3% similar) in 245 aa overlap (1-243:8-249) 10 20 30 40 50 pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYC ::: ::.: :.: .:::.::::::::::::: ::.::.:::::::::::::: CCDS11 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 VRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPED ::::::::: :....:::::::::::::::::::::::..::: .:::::::::::::.. CCDS11 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LMDSKLRCVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEEC :::::::::::.: :::: .:.: .: . .::: . :. : : ::.:::..:.:::: CCDS11 LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEEC 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 KRLQGEVQRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLST--RLLALVVLF ::::::...: :::.....: :::.::...:..: :. . . ... : ::.... . CCDS11 KRLQGEMMKLSEENRHLRDE-GLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAI 180 190 200 210 220 230 240 pF1KB3 FIVGVIIGKIAL :: : ..::. : CCDS11 FI-GFFLGKFIL 240 >>CCDS11847.2 VAPA gene_id:9218|Hs108|chr18 (294 aa) initn: 982 init1: 756 opt: 761 Z-score: 790.5 bits: 154.0 E(32554): 1e-37 Smith-Waterman score: 897; 54.2% identity (73.5% similar) in 275 aa overlap (1-230:8-279) 10 20 30 40 50 pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYC ::: ::.: :.: .:::.::::::::::::: ::.::.:::::::::::::: CCDS11 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 VRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPED ::::::::: :....:::::::::::::::::::::::..::: .:::::::::::::.. CCDS11 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE 70 80 90 100 110 120 120 130 pF1KB3 LMDSKLRCVFELPAENDK----P------------------------------------- :::::::::::.: :::: : CCDS11 LMDSKLRCVFEMPNENDKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQ 130 140 150 160 170 180 140 150 160 170 180 pF1KB3 ----HDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEVQRLREENK .:.: .: . .::: . :. : : ::.:::..:.::::::::::...: :::. CCDS11 EKQKNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENR 190 200 210 220 230 190 200 210 220 230 240 pF1KB3 QFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGKIAL ....: :::.::...:..: :. . . ... ... : .:.:. CCDS11 HLRDE-GLRLRKVAHSDKPGSTSTASFRDN-VTSPLPSLLVVIAAIFIGFFLGKFIL 240 250 260 270 280 290 >>CCDS56198.1 VAPB gene_id:9217|Hs108|chr20 (99 aa) initn: 463 init1: 463 opt: 467 Z-score: 496.8 bits: 98.1 E(32554): 2.4e-21 Smith-Waterman score: 467; 80.0% identity (87.8% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR :::::::::: : . . ... .: . CCDS56 IDAGASINVSGRRWTADEEDSAEQQPHFSISPNWEGRRP 70 80 90 243 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:11:57 2016 done: Sat Nov 5 05:11:58 2016 Total Scan time: 2.040 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]