Result of FASTA (omim) for pF1KB3502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3502, 243 aa
  1>>>pF1KB3502 243 - 243 aa - 243 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8839+/-0.000374; mu= 13.4005+/- 0.023
 mean_var=99.0987+/-19.738, 0's: 0 Z-trim(114.8): 9  B-trim: 1261 in 1/50
 Lambda= 0.128837
 statistics sampled from 24883 (24889) to 24883 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.292), width:  16
 Scan time:  5.900

The best scores are:                                      opt bits E(85289)
NP_004729 (OMIM: 182980,605704,608627) vesicle-ass ( 243) 1570 301.8 7.2e-82
NP_919415 (OMIM: 605703) vesicle-associated membra ( 249) 1014 198.4 9.4e-51
XP_016881568 (OMIM: 605703) PREDICTED: vesicle-ass ( 236)  934 183.6 2.7e-46
NP_003565 (OMIM: 605703) vesicle-associated membra ( 294)  761 151.5 1.5e-36
XP_011524071 (OMIM: 605703) PREDICTED: vesicle-ass ( 281)  681 136.6 4.4e-32
NP_001182606 (OMIM: 182980,605704,608627) vesicle- (  99)  467 96.4 1.9e-20


>>NP_004729 (OMIM: 182980,605704,608627) vesicle-associa  (243 aa)
 initn: 1570 init1: 1570 opt: 1570  Z-score: 1590.8  bits: 301.8 E(85289): 7.2e-82
Smith-Waterman score: 1570; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243)

               10        20        30        40        50        60
pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK
              190       200       210       220       230       240

          
pF1KB3 IAL
       :::
NP_004 IAL
          

>>NP_919415 (OMIM: 605703) vesicle-associated membrane p  (249 aa)
 initn: 990 init1: 800 opt: 1014  Z-score: 1032.1  bits: 198.4 E(85289): 9.4e-51
Smith-Waterman score: 1014; 62.9% identity (85.3% similar) in 245 aa overlap (1-243:8-249)

                      10        20        30        40        50   
pF1KB3        MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYC
              ::: ::.: :.:  .:::.::::::::::::: ::.::.::::::::::::::
NP_919 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB3 VRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPED
       ::::::::: :....:::::::::::::::::::::::..::: .:::::::::::::..
NP_919 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB3 LMDSKLRCVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEEC
       :::::::::::.: :::: .:.: .: .  .::: . :.  :  : ::.:::..:.::::
NP_919 LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEEC
              130       140       150        160       170         

           180       190       200       210       220         230 
pF1KB3 KRLQGEVQRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLST--RLLALVVLF
       ::::::...: :::.....: :::.::...:..: :. . . ...  :    ::.... .
NP_919 KRLQGEMMKLSEENRHLRDE-GLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAI
     180       190        200       210       220       230        

             240   
pF1KB3 FIVGVIIGKIAL
       :: : ..::. :
NP_919 FI-GFFLGKFIL
      240          

>>XP_016881568 (OMIM: 605703) PREDICTED: vesicle-associa  (236 aa)
 initn: 910 init1: 720 opt: 934  Z-score: 952.1  bits: 183.6 E(85289): 2.7e-46
Smith-Waterman score: 934; 63.1% identity (85.8% similar) in 225 aa overlap (21-243:15-236)

               10        20        30        40        50        60
pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
                           :::::::::::: ::.::.:::::::::::::::::::::
XP_016       MLQSKYSKMFIVECPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
       :: :....:::::::::::::::::::::::..::: .:::::::::::::..:::::::
XP_016 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KB3 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
       ::::.: :::: .:.: .: .  .::: . :.  :  : ::.:::..:.::::::::::.
XP_016 CVFEMPNENDKLNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEECKRLQGEM
          120       130       140        150       160       170   

              190       200       210       220         230        
pF1KB3 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLST--RLLALVVLFFIVGVII
       ..: :::.....: :::.::...:..: :. . . ...  :    ::.... .:: : ..
XP_016 MKLSEENRHLRDE-GLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFI-GFFL
           180        190       200       210       220        230 

      240   
pF1KB3 GKIAL
       ::. :
XP_016 GKFIL
            

>>NP_003565 (OMIM: 605703) vesicle-associated membrane p  (294 aa)
 initn: 982 init1: 756 opt: 761  Z-score: 777.0  bits: 151.5 E(85289): 1.5e-36
Smith-Waterman score: 897; 54.2% identity (73.5% similar) in 275 aa overlap (1-230:8-279)

                      10        20        30        40        50   
pF1KB3        MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYC
              ::: ::.: :.:  .:::.::::::::::::: ::.::.::::::::::::::
NP_003 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB3 VRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPED
       ::::::::: :....:::::::::::::::::::::::..::: .:::::::::::::..
NP_003 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
               70        80        90       100       110       120

           120       130                                           
pF1KB3 LMDSKLRCVFELPAENDK----P-------------------------------------
       :::::::::::.: ::::    :                                     
NP_003 LMDSKLRCVFEMPNENDKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQ
              130       140       150       160       170       180

                140       150       160       170       180        
pF1KB3 ----HDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEVQRLREENK
           .:.: .: .  .::: . :.  :  : ::.:::..:.::::::::::...: :::.
NP_003 EKQKNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENR
              190       200        210       220       230         

      190       200       210       220       230       240     
pF1KB3 QFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGKIAL  
       ....: :::.::...:..: :. . . ... ... : .:.:.               
NP_003 HLRDE-GLRLRKVAHSDKPGSTSTASFRDN-VTSPLPSLLVVIAAIFIGFFLGKFIL
     240        250       260        270       280       290    

>>XP_011524071 (OMIM: 605703) PREDICTED: vesicle-associa  (281 aa)
 initn: 902 init1: 676 opt: 681  Z-score: 696.9  bits: 136.6 E(85289): 4.4e-32
Smith-Waterman score: 817; 53.7% identity (72.9% similar) in 255 aa overlap (21-230:15-266)

               10        20        30        40        50        60
pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
                           :::::::::::: ::.::.:::::::::::::::::::::
XP_011       MLQSKYSKMFIVECPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
       :: :....:::::::::::::::::::::::..::: .:::::::::::::..:::::::
XP_011 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
           60        70        80        90       100       110    

              130                                                  
pF1KB3 CVFELPAENDK----P-----------------------------------------HDV
       ::::.: ::::    :                                         .:.
XP_011 CVFEMPNENDKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQEKQKNDM
          120       130       140       150       160       170    

         140       150       160       170       180       190     
pF1KB3 EINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEVQRLREENKQFKEEDG
       : .: .  .::: . :.  :  : ::.:::..:.::::::::::...: :::.....: :
XP_011 EPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDE-G
          180       190        200       210       220       230   

         200       210       220       230       240     
pF1KB3 LRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGKIAL  
       ::.::...:..: :. . . ... ... : .:.:.               
XP_011 LRLRKVAHSDKPGSTSTASFRDN-VTSPLPSLLVVIAAIFIGFFLGKFIL
            240       250        260       270       280 

>>NP_001182606 (OMIM: 182980,605704,608627) vesicle-asso  (99 aa)
 initn: 463 init1: 463 opt: 467  Z-score: 488.1  bits: 96.4 E(85289): 1.9e-20
Smith-Waterman score: 467; 80.0% identity (87.8% similar) in 90 aa overlap (1-90:1-90)

               10        20        30        40        50        60
pF1KB3 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
       ::::::::::      : . . ... .: .                              
NP_001 IDAGASINVSGRRWTADEEDSAEQQPHFSISPNWEGRRP                     
               70        80        90                              




243 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:11:58 2016 done: Sat Nov  5 05:11:59 2016
 Total Scan time:  5.900 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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