FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3505, 354 aa 1>>>pF1KB3505 354 - 354 aa - 354 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9560+/-0.0005; mu= 18.4399+/- 0.031 mean_var=65.5889+/-12.924, 0's: 0 Z-trim(108.4): 96 B-trim: 401 in 1/53 Lambda= 0.158365 statistics sampled from 16388 (16492) to 16388 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.193), width: 16 Scan time: 7.420 The best scores are: opt bits E(85289) NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 2326 540.7 1.8e-153 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 2209 514.0 2e-145 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 2077 483.8 2.4e-136 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 2006 467.5 1.6e-131 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 1849 431.7 1.1e-120 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 1849 431.7 1.1e-120 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 1849 431.7 1.1e-120 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 1770 413.6 2.8e-115 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 1703 398.4 1.3e-110 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 1691 395.6 8.6e-110 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1685 394.3 2.2e-109 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1678 392.7 6.7e-109 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1678 392.7 6.7e-109 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1653 386.9 3.5e-107 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1653 386.9 3.5e-107 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 1598 374.3 1.7e-103 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1588 372.1 1e-102 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 1420 333.7 3.4e-91 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 1372 322.7 6.5e-88 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1167 275.9 9.4e-74 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1166 275.7 1.1e-73 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1129 267.2 3.9e-71 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 997 237.0 4.1e-62 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 991 235.6 1.1e-61 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 988 235.0 1.7e-61 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 923 220.2 6e-57 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 912 217.7 3.4e-56 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 881 210.4 3.2e-54 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 883 211.0 3.3e-54 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 828 198.5 2.4e-50 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 811 194.6 3e-49 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 811 194.6 3e-49 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 801 192.3 1.5e-48 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 805 193.5 1.7e-48 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 804 193.3 2e-48 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 799 191.9 2e-48 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 747 179.9 6.1e-45 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 746 179.7 7.9e-45 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 744 179.2 8.9e-45 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 744 179.3 1.1e-44 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 710 171.4 2.1e-42 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 663 160.7 4e-39 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 663 160.7 4e-39 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 663 160.7 4e-39 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 661 160.3 5.3e-39 XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 644 156.4 8.1e-38 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 644 156.4 8.1e-38 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 637 154.8 2.5e-37 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 637 154.8 2.5e-37 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 637 154.8 2.9e-37 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 2326 init1: 2326 opt: 2326 Z-score: 2876.2 bits: 540.7 E(85289): 1.8e-153 Smith-Waterman score: 2326; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 2230 init1: 2209 opt: 2209 Z-score: 2731.7 bits: 514.0 E(85289): 2e-145 Smith-Waterman score: 2209; 93.8% identity (98.9% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: : NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT :::.::::::.:::::::::::::::::::::::::..::::::::::::::.:::: :: NP_006 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK ::::::::::.:.::::::.:::::::::::.:::::::::.: ::::::::::::::: NP_006 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA ::::::::::::::::::::.::::::::::::::::::.::::::::::.::::::::: NP_006 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::.:::::::::::::::::::::::::::::::::::::.:::. NP_006 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY 310 320 330 340 350 >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 1468 init1: 1468 opt: 2077 Z-score: 2568.7 bits: 483.8 E(85289): 2.4e-136 Smith-Waterman score: 2077; 87.9% identity (95.8% similar) in 355 aa overlap (1-354:1-355) 10 20 30 40 50 60 pF1KB3 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG ::::.:::::::.:::::::.::::::::::::::::::::::::::::::::::::: : NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFM ::::::.::.:::::::::::.::..::: :.:::.: .:::::::::.:. .::: : . NP_002 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 TAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRV .:.:::.::: : ::::::.::::::::::::::::::.:::: .::::::::::::: NP_002 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEE ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_002 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEA ::::::::::::::::::::::::::::::::::::::: .::::::.:::.:.: :.:: NP_002 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 AAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :.::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_001243343 (OMIM: 139310) guanine nucleotide-binding (302 aa) initn: 2006 init1: 2006 opt: 2006 Z-score: 2482.0 bits: 467.5 E(85289): 1.6e-131 Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 302 aa overlap (53-354:1-302) 30 40 50 60 70 80 pF1KB3 LREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSII :::::::::::::::::::::::::::::: NP_001 MKIIHEAGYSEEECKQYKAVVYSNTIQSII 10 20 30 90 100 110 120 130 140 pF1KB3 AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 SREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 GQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 SIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTH 220 230 240 250 260 270 330 340 350 pF1KB3 FTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::: NP_001 FTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 >>NP_001159897 (OMIM: 139360,192605) guanine nucleotide- (318 aa) initn: 1468 init1: 1468 opt: 1849 Z-score: 2287.9 bits: 431.7 E(85289): 1.1e-120 Smith-Waterman score: 1849; 87.3% identity (95.3% similar) in 316 aa overlap (40-354:3-318) 10 20 30 40 50 60 pF1KB3 KAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQY ::::::::::::::::::: :::::::.:: NP_001 MRGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 70 80 90 100 110 120 pF1KB3 KAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFMTAELAGVIK .:::::::::::.::..::: :.:::.: .:::::::::.:. .::: : . .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 RLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.::::::::::::::::::.:::: .:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 LFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFE :::::::::::::::::::::::::::::: .::::::.:::.:.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 220 230 240 250 260 270 310 320 330 340 350 pF1KB3 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 310 >>NP_001269548 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1468 init1: 1468 opt: 1849 Z-score: 2287.5 bits: 431.7 E(85289): 1.1e-120 Smith-Waterman score: 1849; 87.3% identity (95.3% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB3 KAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQY ::::::::::::::::::: :::::::.:: NP_001 MEYAGHLPASSAQGTILACTSCTGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFMTAELAGVIK .:::::::::::.::..::: :.:::.: .:::::::::.:. .::: : . .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 RLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.::::::::::::::::::.:::: .:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFE :::::::::::::::::::::::::::::: .::::::.:::.:.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269549 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1468 init1: 1468 opt: 1849 Z-score: 2287.5 bits: 431.7 E(85289): 1.1e-120 Smith-Waterman score: 1849; 87.3% identity (95.3% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB3 KAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQY ::::::::::::::::::: :::::::.:: NP_001 MTEGVKTLGWTKQKGGCHWGRSEGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFMTAELAGVIK .:::::::::::.::..::: :.:::.: .:::::::::.:. .::: : . .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 RLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.::::::::::::::::::.:::: .:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFE :::::::::::::::::::::::::::::: .::::::.:::.:.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269546 (OMIM: 139360,192605) guanine nucleotide- (303 aa) initn: 1468 init1: 1468 opt: 1770 Z-score: 2190.6 bits: 413.6 E(85289): 2.8e-115 Smith-Waterman score: 1770; 86.8% identity (95.0% similar) in 303 aa overlap (53-354:1-303) 30 40 50 60 70 80 pF1KB3 LREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSII :::::: :::::::.::.:::::::::::. NP_001 MKIIHEDGYSEEECRQYRAVVYSNTIQSIM 10 20 30 90 100 110 120 130 140 pF1KB3 AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFMTAELAGVIKRLWKDSGVQACFN ::..::: :.:::.: .:::::::::.:. .::: : . .:.:::.::: : ::::::. NP_001 AIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFG 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 RSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV ::::::::::::::::::.:::: .::::::::::::::::::::::::::::::::::: NP_001 RSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 GGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 TSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYT ::::::::::::::::: .::::::.:::.:.: :.:::.::: .::::::::::::::: NP_001 TSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYT 220 230 240 250 260 270 330 340 350 pF1KB3 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF ::::::::::::::::::::::::::::::::: NP_001 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 >>NP_620073 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 1520 init1: 1047 opt: 1703 Z-score: 2106.9 bits: 398.4 E(85289): 1.3e-110 Smith-Waterman score: 1703; 72.8% identity (87.1% similar) in 356 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG ::::::::..::.:::: :..::.::: .::..::::::::::::::::::::::::: : NP_620 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAE--EGF .: :. :::: :::::::::. ::.::: : :..::. : ::... ... : : : NP_620 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 MTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTR .::: ... ::: :::.: :::::::::::::: :::..::::. .: ::.::.:::: NP_620 -SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTR 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 VKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE ::::::::::::::.:::..:::::::::::::::::: ::::::::::: :: :: ::: NP_620 VKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 EMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEE ::::::.:::::::::::::::::::::::::.:::::::::::::.:::.: ... : NP_620 TTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSAFTE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :.:::: :.:. :: :::::: ::::::.:.:::::::::::: .::. :::. NP_620 AVAYIQAQYESKNKSAH-KEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGLY 300 310 320 330 340 350 >>NP_066268 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 1520 init1: 1037 opt: 1691 Z-score: 2092.1 bits: 395.6 E(85289): 8.6e-110 Smith-Waterman score: 1691; 72.8% identity (86.8% similar) in 356 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG ::::::::..::.:::: :..::.::: .::..::::::::::::::::::::::::: : NP_066 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAE--EGF .: :. :::: :::::::::. ::.::: : :..::. : ::... ... : : : NP_066 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 MTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTR .::: ... ::: :::.: :::::::::::::: :::..::::. .: ::.::.:::: NP_066 -SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTR 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 VKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE ::::::::::::::.:::..:::::::::::::::::: ::::::::::: :: :: ::: NP_066 VKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 EMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEE ::::::. :::::::::.: :::::::::::::: :::::::::::.:::.: ::::. NP_066 TTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYED 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::: :::. : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_066 AAAYIQAQFESKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 300 310 320 330 340 350 354 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:27:41 2016 done: Thu Nov 3 13:27:42 2016 Total Scan time: 7.420 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]