FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3512, 414 aa 1>>>pF1KB3512 414 - 414 aa - 414 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7900+/-0.000531; mu= 13.0162+/- 0.034 mean_var=265.8293+/-61.344, 0's: 0 Z-trim(116.1): 120 B-trim: 2902 in 2/49 Lambda= 0.078663 statistics sampled from 26905 (27068) to 26905 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.317), width: 16 Scan time: 7.040 The best scores are: opt bits E(85289) XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 2826 334.5 3e-91 NP_031401 (OMIM: 605078,612069) TAR DNA-binding pr ( 414) 2826 334.5 3e-91 NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 417 60.9 5.3e-09 NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 410 60.3 1e-08 NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 408 60.0 1.1e-08 NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 406 59.6 1.2e-08 XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 404 59.5 1.5e-08 NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 404 59.5 1.5e-08 NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 402 59.2 1.7e-08 XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 400 59.0 2.1e-08 NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 400 59.0 2.1e-08 XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 400 59.0 2.1e-08 NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 391 58.0 4.3e-08 XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 388 57.6 4.9e-08 NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 386 57.4 5.9e-08 NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 380 56.6 9.1e-08 XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 341 52.3 2.1e-06 XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 324 50.4 8.2e-06 XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 321 50.1 1e-05 NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 319 49.8 1.2e-05 NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 317 49.6 1.4e-05 XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 317 49.6 1.4e-05 XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 317 49.6 1.4e-05 XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 315 49.4 1.7e-05 NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 315 49.4 1.7e-05 NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 310 48.6 2.1e-05 NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 304 47.9 3.4e-05 XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 304 48.0 3.6e-05 XP_016881354 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 446) 259 43.2 0.0016 XP_016881350 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 447) 259 43.2 0.0016 XP_016881351 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 447) 259 43.2 0.0016 NP_001020260 (OMIM: 612679) CUGBP Elav-like family ( 448) 259 43.2 0.0016 NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 262 43.9 0.0016 XP_016881341 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 474) 259 43.2 0.0016 XP_016881339 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 475) 259 43.2 0.0016 XP_016881335 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 476) 259 43.2 0.0016 XP_011524389 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 494) 259 43.3 0.0016 XP_016881329 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 496) 259 43.3 0.0017 XP_016881352 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 446) 258 43.1 0.0017 XP_016881353 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 446) 258 43.1 0.0017 XP_016881349 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 447) 258 43.1 0.0017 XP_016881346 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 454) 258 43.1 0.0017 XP_016881338 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 473) 258 43.1 0.0017 XP_016881340 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 474) 258 43.1 0.0017 XP_016881337 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 474) 258 43.1 0.0017 >>XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR DNA- (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>NP_031401 (OMIM: 605078,612069) TAR DNA-binding protei (414 aa) initn: 2826 init1: 2826 opt: 2826 Z-score: 1759.2 bits: 334.5 E(85289): 3e-91 Smith-Waterman score: 2826; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB3 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 KEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 KQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 NNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQ 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 REPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM 370 380 390 400 410 >>NP_112556 (OMIM: 602688) heterogeneous nuclear ribonuc (332 aa) initn: 395 init1: 195 opt: 417 Z-score: 282.6 bits: 60.9 E(85289): 5.3e-09 Smith-Waterman score: 435; 30.4% identity (60.9% similar) in 312 aa overlap (78-374:47-329) 50 60 70 80 90 100 pF1KB3 SQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLI : ..... : : .: : .. . : .. NP_112 ENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGK---MF 20 30 40 50 60 70 110 120 130 140 150 160 pF1KB3 VLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQR-H : :: : :...:::.::. ::::. .: : .::.:.::::. : . . ::..:. : NP_112 VGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEH 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB3 MIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIP-KP .::: : : .. . .:. .:.::: . . ::...::.:...:.. . .: : NP_112 RLDGRVIDPK--KAMAMKKDPV--KKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDP 140 150 160 170 180 230 240 250 260 270 pF1KB3 ----FRAFAFVTFADDQIAQSLCGEDL-IIKGISVHISNAEPKHNSNRQLERSGRFG--- :.:.:.:: ... .... . . ..: . .:. :.::. ..: :: : NP_112 KLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRN 190 200 210 220 230 240 280 290 300 310 320 330 pF1KB3 -GNPGGFGNQGGFGNSRGGGAGLGN--NQGSNM--GGGMNFGAFSINPAMMAAAQAALQS :: :. :. :: :.:.. . : :: ::: .. : : ..:... .: NP_112 RGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSP------------ 250 260 270 280 290 340 350 360 370 380 390 pF1KB3 SWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAG .:..:. :: : . .::. . .: :. .:.: NP_112 -YGYYGY--------GP-GYDYSQGSTNYGKSQRRGGHQNNYKPY 300 310 320 330 400 410 pF1KB3 SGSGFNGGFGSSMDSKSSGWGM >>NP_112740 (OMIM: 607137,609115) heterogeneous nuclear (420 aa) initn: 293 init1: 183 opt: 410 Z-score: 277.3 bits: 60.3 E(85289): 1e-08 Smith-Waterman score: 431; 29.3% identity (59.6% similar) in 317 aa overlap (85-392:129-410) 60 70 80 90 100 110 pF1KB3 RLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWK ..: .: ..... : . ... :: : NP_112 AAAAAATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWD 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB3 TTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMS-QRHMIDGRWC :...:: ::.: ::::. .: : ::.:.::::: : . . ::. ..: .::. NP_112 TSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLI 160 170 180 190 200 210 180 190 200 210 220 pF1KB3 DCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIP-----KPFRA : : .. .... : .::::: . : .:....:.:. .:.. .. .: . :. NP_112 DPKRAKALKGKEPP---KKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRG 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB3 FAFVTFADDQ-IAQSLCGEDLIIKGISVHISNAEPK--HNSNRQLERSGRFGGNPGGFGN : :.:..:.. . . : .. : . . .:. :.:: . ...: ...:: :. :: :. NP_112 FCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGR-GAAAGGRGG 280 290 300 310 320 330 290 300 310 320 330 340 pF1KB3 QGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQN : :: : : . ::: : ...: .. :..: ..:: NP_112 TRG----RGRGQGQNWNQGFNNYYDQGYGNYN--------------SAYG------GDQN 340 350 360 370 350 360 370 380 390 400 pF1KB3 QSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSM :: .: . . :. : ..:.: .:::..: .:.:: .: NP_112 YSGYGGYDYTGYNY---GNYGYGQGYADYSGQQST----YGKASRGGGNHQNNYQPY 380 390 400 410 420 410 pF1KB3 DSKSSGWGM >>NP_112738 (OMIM: 601324) heterogeneous nuclear ribonuc (355 aa) initn: 328 init1: 205 opt: 408 Z-score: 276.8 bits: 60.0 E(85289): 1.1e-08 Smith-Waterman score: 409; 30.0% identity (61.7% similar) in 290 aa overlap (81-349:71-354) 60 70 80 90 100 pF1KB3 MRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSD---LI .: . :: ..:. . ..:. . .. NP_112 AGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMF 50 60 70 80 90 100 110 120 130 140 150 160 pF1KB3 VLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQR-H . :: : ::..:::.::: ::::. .: : ::.:.::::: : : :. :::.:. : NP_112 IGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEH 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB3 MIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIP--- ..:. : : .. ... ::. .:.::: . : :...::.:. .:.: .. .: NP_112 KLNGKVIDPKRAKAMKTK-EPV--KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDN 170 180 190 200 210 230 240 250 260 270 pF1KB3 --KPFRAFAFVTFADDQIAQSLCGEDLIIKGIS---VHISNAEPKHNSNRQLERSGRF-- . :.: :.:: ... .... . :.: .... .. ......: : : NP_112 KTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAG 220 230 240 250 260 270 280 290 300 310 320 pF1KB3 -----GGNPGGFGNQGGFGNSRGGGAG-LG-NNQGSNMGGGMNFGAFSINPAMMAAAQAA ::.:. ::: ..: . : : : :.:: . ::... .. : . . . NP_112 RARGRGGGPSQNWNQG-YSNYWNQGYGNYGYNSQGYGGYGGYDYTGY--NNYYGYGDYSN 280 290 300 310 320 330 330 340 350 360 370 380 pF1KB3 LQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSAS ::..: .. ...::. : NP_112 QQSGYGKVSRRGGHQNSYKPY 340 350 414 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:28:18 2016 done: Thu Nov 3 13:28:19 2016 Total Scan time: 7.040 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]