FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3539, 344 aa 1>>>pF1KB3539 344 - 344 aa - 344 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5258+/-0.000398; mu= 14.9423+/- 0.025 mean_var=70.9711+/-14.478, 0's: 0 Z-trim(111.7): 90 B-trim: 0 in 0/52 Lambda= 0.152242 statistics sampled from 20310 (20400) to 20310 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.239), width: 16 Scan time: 7.580 The best scores are: opt bits E(85289) XP_006713861 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 XP_006713862 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 XP_006713863 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 XP_005247912 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 XP_011511562 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 XP_006713864 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 2340 523.3 2.9e-148 NP_997708 (OMIM: 604015) beta-1,4-galactosyltransf ( 344) 2340 523.3 2.9e-148 NP_003769 (OMIM: 604015) beta-1,4-galactosyltransf ( 344) 2340 523.3 2.9e-148 XP_016862890 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 303) 1519 343.0 5e-94 NP_001186802 (OMIM: 604014) beta-1,4-galactosyltra ( 393) 1018 233.0 8.3e-61 NP_001186803 (OMIM: 604014) beta-1,4-galactosyltra ( 393) 1018 233.0 8.3e-61 NP_003770 (OMIM: 604014) beta-1,4-galactosyltransf ( 393) 1018 233.0 8.3e-61 XP_005245623 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 393) 1018 233.0 8.3e-61 XP_016858205 (OMIM: 604013) PREDICTED: beta-1,4-ga ( 372) 953 218.7 1.6e-56 NP_001005417 (OMIM: 604013) beta-1,4-galactosyltra ( 372) 953 218.7 1.6e-56 XP_016858206 (OMIM: 604013) PREDICTED: beta-1,4-ga ( 372) 953 218.7 1.6e-56 NP_003771 (OMIM: 604013) beta-1,4-galactosyltransf ( 372) 953 218.7 1.6e-56 NP_085076 (OMIM: 604013) beta-1,4-galactosyltransf ( 401) 953 218.7 1.7e-56 NP_001488 (OMIM: 137060,607091) beta-1,4-galactosy ( 398) 937 215.2 1.9e-55 XP_011508395 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 310) 915 210.3 4.4e-54 XP_016858203 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 310) 915 210.3 4.4e-54 NP_004767 (OMIM: 604016) beta-1,4-galactosyltransf ( 388) 723 168.2 2.6e-41 XP_006722642 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 338) 717 166.9 5.9e-41 XP_016881578 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 338) 717 166.9 5.9e-41 NP_001317499 (OMIM: 604017) beta-1,4-galactosyltra ( 343) 717 166.9 5.9e-41 XP_005258444 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 370) 717 166.9 6.3e-41 NP_004766 (OMIM: 604017) beta-1,4-galactosyltransf ( 382) 717 166.9 6.5e-41 XP_006722641 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 344) 696 162.2 1.5e-39 XP_016881580 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 269) 651 152.3 1.1e-36 XP_016881579 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 274) 651 152.3 1.1e-36 XP_016858204 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 227) 599 140.8 2.7e-33 XP_016881581 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 202) 563 132.9 5.8e-31 XP_005251497 (OMIM: 137060,607091) PREDICTED: beta ( 357) 561 132.6 1.3e-30 NP_009186 (OMIM: 130070,604327) beta-1,4-galactosy ( 327) 396 96.3 9.5e-20 XP_016864488 (OMIM: 130070,604327) PREDICTED: beta ( 213) 328 81.3 2.1e-15 XP_006714879 (OMIM: 130070,604327) PREDICTED: beta ( 167) 221 57.8 2e-08 >>XP_006713861 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_006 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_006713862 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_006 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_006713863 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_006 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_005247912 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_005 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_011511562 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_011 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_006713864 (OMIM: 604015) PREDICTED: beta-1,4-galact (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_006 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>NP_997708 (OMIM: 604015) beta-1,4-galactosyltransferas (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: NP_997 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>NP_003769 (OMIM: 604015) beta-1,4-galactosyltransferas (344 aa) initn: 2340 init1: 2340 opt: 2340 Z-score: 2782.7 bits: 523.3 E(85289): 2.9e-148 Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 250 260 270 280 290 300 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: NP_003 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 310 320 330 340 >>XP_016862890 (OMIM: 604015) PREDICTED: beta-1,4-galact (303 aa) initn: 1519 init1: 1519 opt: 1519 Z-score: 1809.0 bits: 343.0 E(85289): 5e-94 Smith-Waterman score: 1953; 88.1% identity (88.1% similar) in 344 aa overlap (1-344:1-303) 10 20 30 40 50 60 pF1KB3 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYR--------------- 190 200 210 220 250 260 270 280 290 300 pF1KB3 EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE :::::::::::::::::::::::::::::::::: XP_016 --------------------------VELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE 230 240 250 310 320 330 340 pF1KB3 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA :::::::::::::::::::::::::::::::::::::::::::: XP_016 RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA 260 270 280 290 300 >>NP_001186802 (OMIM: 604014) beta-1,4-galactosyltransfe (393 aa) initn: 914 init1: 486 opt: 1018 Z-score: 1212.6 bits: 233.0 E(85289): 8.3e-61 Smith-Waterman score: 1018; 56.7% identity (75.4% similar) in 268 aa overlap (74-339:74-341) 50 60 70 80 90 100 pF1KB3 AKEFMANFHKTLILGKGKTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQA : :: :: : : .. :.: .: :. NP_001 PTFDYSHPRDVYSNLSHLPGAPGGPPAPQGLPYCPERSPLLVGPVSVSFSPVPSLAEIVE 50 60 70 80 90 100 110 120 130 140 150 160 pF1KB3 ENPKVSRG-RYRPQECKALQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQ .::.: : :::: :. .:.::.:::: ::.:: :: ::::::::::: :::::::: NP_001 RNPRVEPGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQ 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB3 AEGKKFNRAKLLNVGYLEALKEENWDCFIFHDVDLVPENDFNLYKCEEH-PKHLVVGRNS : . :::::::::: :::..:.:::...:::::.:::: ::: :. . :.:..:. :. NP_001 AGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNK 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB3 TGYRLRYSGYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEV :: : : :::::.::. .:..:.::: :.::::::::::. ::.: :::::: : NP_001 FGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSV 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB3 GKYTMVFHTRDKGNEVNAERMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFW :.: :: : ::::: : .:. :: ... : ::..: .:.:.. : .::: :::.: NP_001 GHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIG 290 300 310 320 330 340 pF1KB3 FGA NP_001 TDPRGPRAPSGPRYPPGSSQAFRQEMLQRRPPARPGPLSTANHTALRGSH 350 360 370 380 390 344 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:17:03 2016 done: Sat Nov 5 12:17:04 2016 Total Scan time: 7.580 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]