FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3540, 1175 aa 1>>>pF1KB3540 1175 - 1175 aa - 1175 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4409+/-0.000637; mu= 8.5653+/- 0.039 mean_var=270.7959+/-59.297, 0's: 0 Z-trim(111.2): 219 B-trim: 652 in 2/53 Lambda= 0.077939 statistics sampled from 19572 (19796) to 19572 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.232), width: 16 Scan time: 11.940 The best scores are: opt bits E(85289) XP_016883370 (OMIM: 600810,614669) PREDICTED: 1-ph (1175) 7740 886.0 0 NP_877949 (OMIM: 600810,614669) 1-phosphatidylinos (1175) 7740 886.0 0 XP_016883369 (OMIM: 600810,614669) PREDICTED: 1-ph (1194) 7605 870.8 0 NP_000924 (OMIM: 600810,614669) 1-phosphatidylinos (1194) 7605 870.8 0 XP_016883372 (OMIM: 600810,614669) PREDICTED: 1-ph (1141) 5963 686.1 3.2e-196 XP_016883375 (OMIM: 600810,614669) PREDICTED: 1-ph ( 926) 5812 669.1 3.6e-191 NP_001166117 (OMIM: 600810,614669) 1-phosphatidyli (1187) 4176 485.2 1e-135 XP_005260785 (OMIM: 600810,614669) PREDICTED: 1-ph ( 938) 4041 469.9 3.2e-131 XP_011527556 (OMIM: 600810,614669) PREDICTED: 1-ph (1046) 4041 470.0 3.5e-131 XP_016883374 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 4041 470.0 3.6e-131 XP_016883373 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 4041 470.0 3.6e-131 XP_016883371 (OMIM: 600810,614669) PREDICTED: 1-ph (1153) 4041 470.0 3.7e-131 XP_006723631 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 4041 470.1 3.8e-131 XP_006723632 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 4041 470.1 3.8e-131 XP_005260781 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 4041 470.1 3.8e-131 XP_016877804 (OMIM: 604114) PREDICTED: 1-phosphati (1204) 2240 267.5 3.5e-70 XP_016877803 (OMIM: 604114) PREDICTED: 1-phosphati (1205) 2238 267.3 4.1e-70 XP_016877806 (OMIM: 604114) PREDICTED: 1-phosphati (1198) 2236 267.1 4.7e-70 XP_016877808 (OMIM: 604114) PREDICTED: 1-phosphati (1136) 2229 266.3 7.9e-70 XP_016877807 (OMIM: 604114) PREDICTED: 1-phosphati (1190) 2228 266.2 8.8e-70 XP_016883242 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 1436 177.1 5.4e-43 XP_011527503 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 1436 177.1 5.4e-43 XP_011527502 (OMIM: 607120,613722) PREDICTED: 1-ph (1144) 1436 177.1 5.5e-43 NP_056007 (OMIM: 607120,613722) 1-phosphatidylinos (1216) 1436 177.1 5.7e-43 XP_016883241 (OMIM: 607120,613722) PREDICTED: 1-ph (1143) 1435 177.0 6e-43 XP_011527501 (OMIM: 607120,613722) PREDICTED: 1-ph (1153) 1435 177.0 6e-43 NP_877398 (OMIM: 607120,613722) 1-phosphatidylinos (1173) 1435 177.0 6.1e-43 NP_001171812 (OMIM: 600230) 1-phosphatidylinositol (1167) 1303 162.2 1.8e-38 NP_000923 (OMIM: 600230) 1-phosphatidylinositol 4, (1234) 1303 162.2 1.8e-38 NP_001303243 (OMIM: 600230) 1-phosphatidylinositol (1234) 1303 162.2 1.8e-38 XP_011543403 (OMIM: 600230) PREDICTED: 1-phosphati (1154) 1268 158.2 2.7e-37 XP_011527505 (OMIM: 607120,613722) PREDICTED: 1-ph ( 625) 1261 157.1 3.1e-37 XP_016873414 (OMIM: 600230) PREDICTED: 1-phosphati ( 703) 1236 154.4 2.4e-36 NP_001271226 (OMIM: 604114) 1-phosphatidylinositol (1181) 1111 140.6 5.6e-32 XP_011519976 (OMIM: 604114) PREDICTED: 1-phosphati (1192) 1102 139.6 1.1e-31 NP_004564 (OMIM: 604114) 1-phosphatidylinositol 4, (1185) 1100 139.4 1.3e-31 NP_001271227 (OMIM: 604114) 1-phosphatidylinositol (1170) 1092 138.4 2.5e-31 XP_016877805 (OMIM: 604114) PREDICTED: 1-phosphati (1201) 1057 134.5 3.8e-30 NP_588614 (OMIM: 608795) 1-phosphatidylinositol 4, ( 789) 674 91.3 2.7e-17 XP_011538154 (OMIM: 608414,610725) PREDICTED: 1-ph (1622) 670 91.2 5.9e-17 XP_016871801 (OMIM: 608414,610725) PREDICTED: 1-ph (1978) 670 91.3 6.7e-17 NP_001159451 (OMIM: 608414,610725) 1-phosphatidyli (1994) 670 91.3 6.7e-17 XP_011538153 (OMIM: 608414,610725) PREDICTED: 1-ph (1623) 668 90.9 6.9e-17 NP_001275918 (OMIM: 608414,610725) 1-phosphatidyli (2286) 670 91.3 7.4e-17 NP_057425 (OMIM: 608414,610725) 1-phosphatidylinos (2302) 670 91.3 7.4e-17 XP_006717951 (OMIM: 608414,610725) PREDICTED: 1-ph (2315) 670 91.3 7.4e-17 XP_011538152 (OMIM: 608414,610725) PREDICTED: 1-ph (1931) 668 91.0 7.7e-17 XP_006717953 (OMIM: 608414,610725) PREDICTED: 1-ph (2008) 668 91.0 7.9e-17 NP_116115 (OMIM: 605939) 1-phosphatidylinositol 4, ( 762) 659 89.5 8.4e-17 XP_006717952 (OMIM: 608414,610725) PREDICTED: 1-ph (2300) 668 91.1 8.6e-17 >>XP_016883370 (OMIM: 600810,614669) PREDICTED: 1-phosph (1175 aa) initn: 7740 init1: 7740 opt: 7740 Z-score: 4723.4 bits: 886.0 E(85289): 0 Smith-Waterman score: 7740; 99.9% identity (100.0% similar) in 1175 aa overlap (1-1175:1-1175) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB3 LEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV ::::::::::::::::::::::::::::::::::: XP_016 LEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV 1150 1160 1170 >>NP_877949 (OMIM: 600810,614669) 1-phosphatidylinositol (1175 aa) initn: 7740 init1: 7740 opt: 7740 Z-score: 4723.4 bits: 886.0 E(85289): 0 Smith-Waterman score: 7740; 99.9% identity (100.0% similar) in 1175 aa overlap (1-1175:1-1175) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_877 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB3 LEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV ::::::::::::::::::::::::::::::::::: NP_877 LEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV 1150 1160 1170 >>XP_016883369 (OMIM: 600810,614669) PREDICTED: 1-phosph (1194 aa) initn: 7603 init1: 7603 opt: 7605 Z-score: 4641.3 bits: 870.8 E(85289): 0 Smith-Waterman score: 7605; 98.8% identity (99.3% similar) in 1169 aa overlap (1-1168:1-1169) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB3 LEHLEFLEKQNEQA-KEMQQMVKLEAEMDRRPATVV ::::::::::::: : . . . ..: : XP_016 LEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 1150 1160 1170 1180 1190 >>NP_000924 (OMIM: 600810,614669) 1-phosphatidylinositol (1194 aa) initn: 7603 init1: 7603 opt: 7605 Z-score: 4641.3 bits: 870.8 E(85289): 0 Smith-Waterman score: 7605; 98.8% identity (99.3% similar) in 1169 aa overlap (1-1168:1-1169) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_000 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB3 LEHLEFLEKQNEQA-KEMQQMVKLEAEMDRRPATVV ::::::::::::: : . . . ..: : NP_000 LEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 1150 1160 1170 1180 1190 >>XP_016883372 (OMIM: 600810,614669) PREDICTED: 1-phosph (1141 aa) initn: 5953 init1: 5953 opt: 5963 Z-score: 3643.7 bits: 686.1 E(85289): 3.2e-196 Smith-Waterman score: 7141; 94.3% identity (94.8% similar) in 1169 aa overlap (1-1168:1-1116) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD ::::::::::::::: XP_016 VIFQALKELGLPSGK--------------------------------------------- 190 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 --------HQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 200 210 220 230 240 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 430 440 450 460 470 480 550 560 570 580 590 600 pF1KB3 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT 610 620 630 640 650 660 730 740 750 760 770 780 pF1KB3 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK 670 680 690 700 710 720 790 800 810 820 830 840 pF1KB3 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK 730 740 750 760 770 780 850 860 870 880 890 900 pF1KB3 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAA 790 800 810 820 830 840 910 920 930 940 950 960 pF1KB3 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ 850 860 870 880 890 900 970 980 990 1000 1010 1020 pF1KB3 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH 910 920 930 940 950 960 1030 1040 1050 1060 1070 1080 pF1KB3 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ 970 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KB3 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ 1030 1040 1050 1060 1070 1080 1150 1160 1170 pF1KB3 LEHLEFLEKQNEQA-KEMQQMVKLEAEMDRRPATVV ::::::::::::: : . . . ..: : XP_016 LEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 1090 1100 1110 1120 1130 1140 >>XP_016883375 (OMIM: 600810,614669) PREDICTED: 1-phosph (926 aa) initn: 5810 init1: 5810 opt: 5812 Z-score: 3553.0 bits: 669.1 E(85289): 3.6e-191 Smith-Waterman score: 5812; 98.6% identity (99.1% similar) in 901 aa overlap (269-1168:1-901) 240 250 260 270 280 290 pF1KB3 VDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMS :::::::::::::::::::::::::::::: XP_016 MQIIEMYEPDEDLKKKGLISSDGFCRYLMS 10 20 30 300 310 320 330 340 350 pF1KB3 DENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVE 40 50 60 70 80 90 360 370 380 390 400 410 pF1KB3 LDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQY 100 110 120 130 140 150 420 430 440 450 460 470 pF1KB3 KMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALR 160 170 180 190 200 210 480 490 500 510 520 530 pF1KB3 SMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKG 220 230 240 250 260 270 540 550 560 570 580 590 pF1KB3 LVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNES 280 290 300 310 320 330 600 610 620 630 640 650 pF1KB3 VGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAM 340 350 360 370 380 390 660 670 680 690 700 710 pF1KB3 QLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKI 400 410 420 430 440 450 720 730 740 750 760 770 pF1KB3 GTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN 460 470 480 490 500 510 780 790 800 810 820 830 pF1KB3 NKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDP 520 530 540 550 560 570 840 850 860 870 880 890 pF1KB3 KKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTT 580 590 600 610 620 630 900 910 920 930 940 950 pF1KB3 AALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHC 640 650 660 670 680 690 960 970 980 990 1000 1010 pF1KB3 TQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVA 700 710 720 730 740 750 1020 1030 1040 1050 1060 1070 pF1KB3 QHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRA 760 770 780 790 800 810 1080 1090 1100 1110 1120 1130 pF1KB3 HQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKK 820 830 840 850 860 870 1140 1150 1160 1170 pF1KB3 VQLEHLEFLEKQNEQA-KEMQQMVKLEAEMDRRPATVV ::::::::::::::: : . . . ..: : XP_016 VQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 880 890 900 910 920 >>NP_001166117 (OMIM: 600810,614669) 1-phosphatidylinosi (1187 aa) initn: 4158 init1: 4158 opt: 4176 Z-score: 2557.6 bits: 485.2 E(85289): 1e-135 Smith-Waterman score: 7706; 98.9% identity (99.0% similar) in 1187 aa overlap (1-1175:1-1187) 10 20 30 40 50 60 pF1KB3 MAKPYEFNWQKEVPSFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_001 MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKK--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKASD 490 500 510 520 530 540 540 550 560 570 580 pF1KB3 ---------GLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNI ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB3 HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB3 LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB3 SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB3 VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB3 GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQ 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB3 SSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAK 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KB3 EHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSD 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KB3 HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLS 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KB3 HDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 pF1KB3 QSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV 1150 1160 1170 1180 >>XP_005260785 (OMIM: 600810,614669) PREDICTED: 1-phosph (938 aa) initn: 4021 init1: 4021 opt: 4041 Z-score: 2476.7 bits: 469.9 E(85289): 3.2e-131 Smith-Waterman score: 5778; 97.3% identity (97.8% similar) in 913 aa overlap (269-1168:1-913) 240 250 260 270 280 290 pF1KB3 VDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMS :::::::::::::::::::::::::::::: XP_005 MQIIEMYEPDEDLKKKGLISSDGFCRYLMS 10 20 30 300 310 320 330 340 350 pF1KB3 DENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVE 40 50 60 70 80 90 360 370 380 390 400 410 pF1KB3 LDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQY 100 110 120 130 140 150 420 430 440 450 460 470 pF1KB3 KMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALR 160 170 180 190 200 210 480 490 500 510 520 530 pF1KB3 SMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKA 220 230 240 250 260 270 540 550 560 570 580 pF1KB3 -----------GLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEER ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEER 280 290 300 310 320 330 590 600 610 620 630 640 pF1KB3 NIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQM 340 350 360 370 380 390 650 660 670 680 690 700 pF1KB3 VSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQ 400 410 420 430 440 450 710 720 730 740 750 760 pF1KB3 VISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPD 460 470 480 490 500 510 770 780 790 800 810 820 pF1KB3 LAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPD 520 530 540 550 560 570 830 840 850 860 870 880 pF1KB3 GFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVT 580 590 600 610 620 630 890 900 910 920 930 940 pF1KB3 PQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKH 640 650 660 670 680 690 950 960 970 980 990 1000 pF1KB3 AKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLT 700 710 720 730 740 750 1010 1020 1030 1040 1050 1060 pF1KB3 SDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLK 760 770 780 790 800 810 1070 1080 1090 1100 1110 1120 pF1KB3 LSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLA 820 830 840 850 860 870 1130 1140 1150 1160 1170 pF1KB3 MKQSKEMDQLKKVQLEHLEFLEKQNEQA-KEMQQMVKLEAEMDRRPATVV ::::::::::::::::::::::::::: : . . . ..: : XP_005 MKQSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNS 880 890 900 910 920 930 XP_005 SMKLQNAN >>XP_011527556 (OMIM: 600810,614669) PREDICTED: 1-phosph (1046 aa) initn: 4021 init1: 4021 opt: 4041 Z-score: 2476.2 bits: 470.0 E(85289): 3.5e-131 Smith-Waterman score: 6438; 97.5% identity (98.0% similar) in 1014 aa overlap (168-1168:8-1021) 140 150 160 170 180 190 pF1KB3 ANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKND :::::::::::::::::::::::::::::: XP_011 MKNICNESITRTFASGKTEKVIFQALKELGLPSGKND 10 20 30 200 210 220 230 240 250 pF1KB3 EIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB3 ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDH 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB3 PLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGK 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB3 AMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB3 ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDN 280 290 300 310 320 330 500 510 520 530 540 pF1KB3 EEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKK------------GLVTVEDE :::::::::::::::::::::::::::::::::::::::: :::::::: XP_011 EEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKASDDLEHENNKKGLVTVEDE 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB3 QAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLK 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB3 THAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKF 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB3 EYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVD 520 530 540 550 560 570 730 740 750 760 770 780 pF1KB3 MYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQR 580 590 600 610 620 630 790 800 810 820 830 840 pF1KB3 ILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSIT 640 650 660 670 680 690 850 860 870 880 890 900 pF1KB3 EKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGV 700 710 720 730 740 750 910 920 930 940 950 960 pF1KB3 EAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIV 760 770 780 790 800 810 970 980 990 1000 1010 1020 pF1KB3 AQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWS 820 830 840 850 860 870 1030 1040 1050 1060 1070 1080 pF1KB3 EMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISM 880 890 900 910 920 930 1090 1100 1110 1120 1130 1140 pF1KB3 ENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLE 940 950 960 970 980 990 1150 1160 1170 pF1KB3 FLEKQNEQA-KEMQQMVKLEAEMDRRPATVV :::::::: : . . . ..: : XP_011 FLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 1000 1010 1020 1030 1040 >>XP_016883374 (OMIM: 600810,614669) PREDICTED: 1-phosph (1093 aa) initn: 4021 init1: 4021 opt: 4041 Z-score: 2476.0 bits: 470.0 E(85289): 3.6e-131 Smith-Waterman score: 6809; 97.7% identity (98.1% similar) in 1068 aa overlap (114-1168:1-1068) 90 100 110 120 130 140 pF1KB3 EAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSP :::::::::::::::::::::::::::::: XP_016 MVAENPEVTKQWVEGLRSIIHNFRANNVSP 10 20 30 150 160 170 180 190 200 pF1KB3 MTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 FSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFY 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB3 DAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYF 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB3 ISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDI 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB3 LFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLE 280 290 300 310 320 330 450 460 470 480 490 500 pF1KB3 PGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIES 340 350 360 370 380 390 510 520 530 540 550 pF1KB3 ADQEEEAHPEFKFGNELSADDLGHKEAVANSVKK------------GLVTVEDEQAWMAS :::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 ADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKASDDLEHENNKKGLVTVEDEQAWMAS 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 YKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 VNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSC 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 GYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPT 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB3 DTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDG 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB3 LQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQ 700 710 720 730 740 750 860 870 880 890 900 910 pF1KB3 MRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGI 760 770 780 790 800 810 920 930 940 950 960 970 pF1KB3 ELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKE 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KB3 KSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTH 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KB3 SAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAI 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KB3 SQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQN 1000 1010 1020 1030 1040 1050 1160 1170 pF1KB3 EQA-KEMQQMVKLEAEMDRRPATVV :: : . . . ..: : XP_016 EQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQNAN 1060 1070 1080 1090 1175 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:02:48 2016 done: Thu Nov 3 21:02:50 2016 Total Scan time: 11.940 Total Display time: 0.460 Function used was FASTA [36.3.4 Apr, 2011]