FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3544, 108 aa 1>>>pF1KB3544 108 - 108 aa - 108 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9216+/-0.00057; mu= 11.5642+/- 0.034 mean_var=56.0159+/-10.968, 0's: 0 Z-trim(112.1): 31 B-trim: 0 in 0/51 Lambda= 0.171364 statistics sampled from 12925 (12956) to 12925 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.398), width: 16 Scan time: 1.430 The best scores are: opt bits E(32554) CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 ( 108) 736 189.1 4.6e-49 CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 ( 108) 641 165.6 5.4e-42 CCDS82423.1 FKBP1B gene_id:2281|Hs108|chr2 ( 79) 447 117.6 1.1e-27 CCDS33153.1 FKBP1B gene_id:2281|Hs108|chr2 ( 80) 415 109.6 2.8e-25 CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 ( 459) 338 91.0 6.5e-19 CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 ( 268) 321 86.7 7.6e-18 CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 ( 457) 321 86.8 1.2e-17 CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 ( 142) 305 82.6 6.9e-17 CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 ( 224) 291 79.2 1.1e-15 CCDS11409.1 FKBP10 gene_id:60681|Hs108|chr17 ( 582) 260 71.8 5.1e-13 CCDS5423.1 FKBP14 gene_id:55033|Hs108|chr7 ( 211) 252 69.6 8.5e-13 CCDS46462.1 FKBP7 gene_id:51661|Hs108|chr2 ( 221) 249 68.8 1.5e-12 CCDS5439.1 FKBP9 gene_id:11328|Hs108|chr7 ( 570) 247 68.6 4.6e-12 CCDS2280.1 FKBP7 gene_id:51661|Hs108|chr2 ( 222) 237 65.9 1.2e-11 CCDS64623.1 FKBP9 gene_id:11328|Hs108|chr7 ( 338) 231 64.5 4.6e-11 CCDS64622.1 FKBP9 gene_id:11328|Hs108|chr7 ( 623) 231 64.6 7.7e-11 CCDS8773.1 FKBP11 gene_id:51303|Hs108|chr12 ( 201) 225 62.9 8.3e-11 >>CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 (108 aa) initn: 736 init1: 736 opt: 736 Z-score: 994.3 bits: 189.1 E(32554): 4.6e-49 Smith-Waterman score: 736; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 70 80 90 100 >>CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 (108 aa) initn: 641 init1: 641 opt: 641 Z-score: 867.4 bits: 165.6 E(32554): 5.4e-42 Smith-Waterman score: 641; 83.3% identity (97.2% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::..:::::::::::::.::::::::::::..:::::::::::::::: .::::::.:. CCDS17 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: CCDS17 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 70 80 90 100 >>CCDS82423.1 FKBP1B gene_id:2281|Hs108|chr2 (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 610.2 bits: 117.6 E(32554): 1.1e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. CCDS82 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: CCDS82 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>CCDS33153.1 FKBP1B gene_id:2281|Hs108|chr2 (80 aa) initn: 426 init1: 407 opt: 415 Z-score: 567.4 bits: 109.6 E(32554): 2.8e-25 Smith-Waterman score: 415; 75.9% identity (89.9% similar) in 79 aa overlap (1-79:1-77) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::..:::::::::::::.::::::::::::..:::::::::::::::: .::::::.:. CCDS33 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::. : . : : : CCDS33 EEGAAQL--GPLSPLPICPHPC 70 80 >>CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 (459 aa) initn: 372 init1: 338 opt: 338 Z-score: 453.0 bits: 91.0 E(32554): 6.5e-19 Smith-Waterman score: 338; 52.0% identity (75.5% similar) in 98 aa overlap (11-108:41-138) 10 20 30 40 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS : : .: :. ::::: : :: ::::: CCDS85 SGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF ::. :.: ::: :::..:. ..: :.::. ..: .:.::::..: : :::.::::: CCDS85 LDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVF 80 90 100 110 120 130 pF1KB3 DVELLKLE .:::.... CCDS85 EVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRF 140 150 160 170 180 190 >>CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 (268 aa) initn: 321 init1: 321 opt: 321 Z-score: 433.9 bits: 86.7 E(32554): 7.6e-18 Smith-Waterman score: 321; 50.0% identity (72.4% similar) in 98 aa overlap (11-108:41-138) 10 20 30 40 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS :.:. : :. ::: : : .::::::: CCDS54 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF .:::.:: : ::: .::..:. ::: :. :. .: .:.::::..: :: .::: : CCDS54 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFF 80 90 100 110 120 130 pF1KB3 DVELLKLE ..::: .. CCDS54 EIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTV 140 150 160 170 180 190 >>CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 (457 aa) initn: 321 init1: 321 opt: 321 Z-score: 430.4 bits: 86.8 E(32554): 1.2e-17 Smith-Waterman score: 321; 50.0% identity (72.4% similar) in 98 aa overlap (11-108:41-138) 10 20 30 40 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS :.:. : :. ::: : : .::::::: CCDS48 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF .:::.:: : ::: .::..:. ::: :. :. .: .:.::::..: :: .::: : CCDS48 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFF 80 90 100 110 120 130 pF1KB3 DVELLKLE ..::: .. CCDS48 EIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTV 140 150 160 170 180 190 >>CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 (142 aa) initn: 296 init1: 296 opt: 305 Z-score: 416.7 bits: 82.6 E(32554): 6.9e-17 Smith-Waterman score: 305; 50.5% identity (72.5% similar) in 91 aa overlap (18-108:47-137) 10 20 30 40 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPF ..:.. .:::: :::: .:::: .:.:: CCDS80 SAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPF 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 KFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKL : :: .::.::..:. : :.. ::.: . .:: : : :: :::::.:::::. CCDS80 VFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 80 90 100 110 120 130 pF1KB3 E : CCDS80 ERRTEL 140 >>CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 (224 aa) initn: 298 init1: 164 opt: 291 Z-score: 395.0 bits: 79.2 E(32554): 1.1e-15 Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (8-108:116-224) 10 20 30 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK .. :: .:::.:. ::: ::: :.:: CCDS96 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT 90 100 110 120 130 140 40 50 60 70 80 pF1KB3 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH ::.. . .: ::..: .: .:::::.:.. :: :..:.: : :..::: :. CCDS96 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ 150 160 170 180 190 200 90 100 pF1KB3 PGI-IPPHATLVFDVELLKLE : :::.: :.:.:::. .. CCDS96 PDAKIPPNAKLTFEVELVDID 210 220 >>CCDS11409.1 FKBP10 gene_id:60681|Hs108|chr17 (582 aa) initn: 257 init1: 257 opt: 260 Z-score: 347.3 bits: 71.8 E(32554): 5.1e-13 Smith-Waterman score: 260; 44.2% identity (66.3% similar) in 95 aa overlap (14-105:53-147) 10 20 30 40 pF1KB3 MGVQVETISPGDGRTFPKR---GQTCVVHYTGMLEDGKKFDSS :. :.. :. ::.: .::::::::: CCDS11 VVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSS 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB3 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF ::: ...: ..: : ..:. : :..: .: . : .::. : :.::: ::: : CCDS11 YDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYF 90 100 110 120 130 140 pF1KB3 DVELLKLE :: :: CCDS11 DVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYD 150 160 170 180 190 200 108 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:35:12 2016 done: Fri Nov 4 02:35:12 2016 Total Scan time: 1.430 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]