FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3544, 108 aa 1>>>pF1KB3544 108 - 108 aa - 108 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2150+/-0.000275; mu= 9.7577+/- 0.017 mean_var=57.8093+/-11.352, 0's: 0 Z-trim(119.2): 53 B-trim: 0 in 0/57 Lambda= 0.168685 statistics sampled from 32805 (32862) to 32805 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.385), width: 16 Scan time: 3.920 The best scores are: opt bits E(85289) NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 736 186.5 7.1e-48 NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 736 186.5 7.1e-48 NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108) 641 163.4 6.5e-41 XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 447 116.1 8e-27 XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 447 116.1 8e-27 XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 447 116.1 8e-27 NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 447 116.1 8e-27 XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 447 116.1 8e-27 NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 447 116.1 8e-27 NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans ( 80) 415 108.3 1.8e-24 XP_011531001 (OMIM: 600620) PREDICTED: peptidyl-pr ( 100) 410 107.2 5.1e-24 NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 338 89.9 3.6e-18 XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 325 86.7 3e-17 NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268) 321 85.7 4e-17 NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 321 85.8 6.4e-17 NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 321 85.8 6.4e-17 NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 321 85.8 6.4e-17 NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 305 81.7 3.4e-16 XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142) 305 81.7 3.4e-16 NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142) 305 81.7 3.4e-16 NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 305 81.7 3.4e-16 XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 291 78.3 4.7e-15 NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 291 78.3 5.4e-15 NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582) 260 71.0 2.3e-12 XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601) 260 71.0 2.4e-12 XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 252 68.8 3.4e-12 NP_060416 (OMIM: 614505,614557) peptidyl-prolyl ci ( 211) 252 68.8 3.7e-12 XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 252 68.9 3.9e-12 NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221) 249 68.1 6.3e-12 XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359) 247 67.7 1.4e-11 NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570) 247 67.8 2e-11 NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans ( 222) 237 65.2 4.8e-11 NP_001271272 (OMIM: 616257) peptidyl-prolyl cis-tr ( 338) 231 63.8 1.9e-10 NP_001271270 (OMIM: 616257) peptidyl-prolyl cis-tr ( 623) 231 63.9 3.3e-10 NP_057678 (OMIM: 610571) peptidyl-prolyl cis-trans ( 201) 225 62.3 3.3e-10 XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510) 223 61.9 1.1e-09 XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266) 217 60.4 1.6e-09 XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282) 217 60.4 1.7e-09 XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 217 60.4 1.9e-09 NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 217 60.4 1.9e-09 NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 217 60.4 2e-09 NP_001186715 (OMIM: 186945) peptidyl-prolyl cis-tr ( 97) 196 55.1 2.3e-08 NP_001137254 (OMIM: 610571) peptidyl-prolyl cis-tr ( 146) 190 53.7 9.2e-08 NP_001295302 (OMIM: 604840) peptidyl-prolyl cis-tr ( 412) 190 53.9 2.3e-07 XP_005246695 (OMIM: 607062) PREDICTED: peptidyl-pr ( 181) 177 50.6 1e-06 XP_011526166 (OMIM: 604840) PREDICTED: peptidyl-pr ( 383) 178 50.9 1.6e-06 NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans ( 413) 178 51.0 1.7e-06 XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-pr ( 413) 178 51.0 1.7e-06 NP_001268233 (OMIM: 604839) inactive peptidyl-prol ( 297) 153 44.8 8.9e-05 >>NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 736 init1: 736 opt: 736 Z-score: 980.5 bits: 186.5 E(85289): 7.1e-48 Smith-Waterman score: 736; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_463 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::::::::::::::::::::::::::::::::::::::::::::::: NP_463 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 70 80 90 100 >>NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 736 init1: 736 opt: 736 Z-score: 980.5 bits: 186.5 E(85289): 7.1e-48 Smith-Waterman score: 736; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 70 80 90 100 >>NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans iso (108 aa) initn: 641 init1: 641 opt: 641 Z-score: 855.5 bits: 163.4 E(85289): 6.5e-41 Smith-Waterman score: 641; 83.3% identity (97.2% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::..:::::::::::::.::::::::::::..:::::::::::::::: .::::::.:. NP_004 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: NP_004 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 70 80 90 100 >>XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-prolyl (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. XP_016 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: XP_016 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-prolyl (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. XP_016 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: XP_016 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-prolyl (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. XP_016 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: XP_016 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-trans (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. NP_001 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: NP_001 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-prolyl (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. XP_016 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: XP_016 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-trans (79 aa) initn: 447 init1: 447 opt: 447 Z-score: 602.5 bits: 116.1 E(85289): 8e-27 Smith-Waterman score: 447; 81.0% identity (96.2% similar) in 79 aa overlap (30-108:1-79) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW ::..:::::::::::::::: .::::::.:. NP_001 MLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::::.::::::: .:: :::::::::.:::.:::.::::::.:: NP_001 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 40 50 60 70 >>NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans iso (80 aa) initn: 426 init1: 407 opt: 415 Z-score: 560.4 bits: 108.3 E(85289): 1.8e-24 Smith-Waterman score: 415; 75.9% identity (89.9% similar) in 79 aa overlap (1-79:1-77) 10 20 30 40 50 60 pF1KB3 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW :::..:::::::::::::.::::::::::::..:::::::::::::::: .::::::.:. NP_473 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 10 20 30 40 50 60 70 80 90 100 pF1KB3 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE :::.::. : . : : : NP_473 EEGAAQL--GPLSPLPICPHPC 70 80 108 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:35:13 2016 done: Fri Nov 4 02:35:13 2016 Total Scan time: 3.920 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]