FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3552, 373 aa 1>>>pF1KB3552 373 - 373 aa - 373 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4729+/-0.000799; mu= 1.1710+/- 0.048 mean_var=255.1025+/-51.022, 0's: 0 Z-trim(117.5): 5 B-trim: 14 in 1/52 Lambda= 0.080300 statistics sampled from 18266 (18271) to 18266 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.561), width: 16 Scan time: 3.300 The best scores are: opt bits E(32554) CCDS7702.1 RASSF7 gene_id:8045|Hs108|chr11 ( 373) 2513 303.2 2.3e-82 CCDS44505.1 RASSF7 gene_id:8045|Hs108|chr11 ( 320) 2121 257.8 9.8e-69 CCDS44506.1 RASSF7 gene_id:8045|Hs108|chr11 ( 337) 2114 257.0 1.8e-68 CCDS8705.1 RASSF8 gene_id:11228|Hs108|chr12 ( 392) 483 68.1 1.5e-11 CCDS53765.1 RASSF8 gene_id:11228|Hs108|chr12 ( 419) 483 68.1 1.6e-11 >>CCDS7702.1 RASSF7 gene_id:8045|Hs108|chr11 (373 aa) initn: 2513 init1: 2513 opt: 2513 Z-score: 1592.0 bits: 303.2 E(32554): 2.3e-82 Smith-Waterman score: 2513; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB3 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA 310 320 330 340 350 360 370 pF1KB3 PEWCPLAAQPQAL ::::::::::::: CCDS77 PEWCPLAAQPQAL 370 >>CCDS44505.1 RASSF7 gene_id:8045|Hs108|chr11 (320 aa) initn: 2197 init1: 2121 opt: 2121 Z-score: 1347.5 bits: 257.8 E(32554): 9.8e-69 Smith-Waterman score: 2121; 99.7% identity (99.7% similar) in 319 aa overlap (1-319:1-319) 10 20 30 40 50 60 pF1KB3 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA ::::::::::::::::: : CCDS44 AALPPPPRPDRGPPGTQWPP 310 320 >>CCDS44506.1 RASSF7 gene_id:8045|Hs108|chr11 (337 aa) initn: 2114 init1: 2114 opt: 2114 Z-score: 1342.8 bits: 257.0 E(32554): 1.8e-68 Smith-Waterman score: 2114; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB3 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA ::::::::::::::::: CCDS44 AALPPPPRPDRGPPGTQVGVVLGGGWEVRTWPSPTPS 310 320 330 >>CCDS8705.1 RASSF8 gene_id:11228|Hs108|chr12 (392 aa) initn: 760 init1: 434 opt: 483 Z-score: 320.8 bits: 68.1 E(32554): 1.5e-11 Smith-Waterman score: 648; 37.9% identity (56.6% similar) in 369 aa overlap (8-307:1-367) 10 20 30 40 50 60 pF1KB3 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL :::::::::.::.::::.: :::::::::::::::.:::..:... :. ::.: CCDS87 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHL 10 20 30 40 50 70 80 90 100 110 pF1KB3 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAA :.: :. . ::.:::::..::::::::. ::.::: ::: : : ::: : : CCDS87 APHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAK 60 70 80 90 100 110 120 130 140 150 pF1KB3 LGCEPRKTLTP-EPA-PSLSRPGPAAPVTPTPG--------------CCT---DLRGL-- : . :.. :: ::. : : . : : : .:. : CCDS87 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 120 130 140 150 160 170 160 170 180 pF1KB3 --------------------------------------ELRVQRNAEELGHEAFWEQELR : ...:: :. .: :::.::. CCDS87 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 180 190 200 210 220 230 190 200 210 220 230 pF1KB3 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPM :: :.. . .:: . .: .:. :: :..:. :. . :: . CCDS87 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB3 ASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQ . ... .. .: .:: ...... : :.: : . :: . ::::.:..:::: :::: CCDS87 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB3 FIQQTGA---ALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAE ::::::. .:: : CCDS87 FIQQTGTKVTVLPAEPIEIEASHADIERGIIILSDKQECKD 360 370 380 390 >>CCDS53765.1 RASSF8 gene_id:11228|Hs108|chr12 (419 aa) initn: 760 init1: 434 opt: 483 Z-score: 320.4 bits: 68.1 E(32554): 1.6e-11 Smith-Waterman score: 648; 37.9% identity (56.6% similar) in 369 aa overlap (8-307:1-367) 10 20 30 40 50 60 pF1KB3 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL :::::::::.::.::::.: :::::::::::::::.:::..:... :. ::.: CCDS53 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHL 10 20 30 40 50 70 80 90 100 110 pF1KB3 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAA :.: :. . ::.:::::..::::::::. ::.::: ::: : : ::: : : CCDS53 APHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAK 60 70 80 90 100 110 120 130 140 150 pF1KB3 LGCEPRKTLTP-EPA-PSLSRPGPAAPVTPTPG--------------CCT---DLRGL-- : . :.. :: ::. : : . : : : .:. : CCDS53 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 120 130 140 150 160 170 160 170 180 pF1KB3 --------------------------------------ELRVQRNAEELGHEAFWEQELR : ...:: :. .: :::.::. CCDS53 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 180 190 200 210 220 230 190 200 210 220 230 pF1KB3 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPM :: :.. . .:: . .: .:. :: :..:. :. . :: . CCDS53 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB3 ASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQ . ... .. .: .:: ...... : :.: : . :: . ::::.:..:::: :::: CCDS53 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB3 FIQQTGA---ALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAE ::::::. .:: : CCDS53 FIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSG 360 370 380 390 400 410 373 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:35:49 2016 done: Fri Nov 4 02:35:49 2016 Total Scan time: 3.300 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]