FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3573, 536 aa 1>>>pF1KB3573 536 - 536 aa - 536 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3637+/-0.000927; mu= 17.9452+/- 0.056 mean_var=64.6260+/-13.259, 0's: 0 Z-trim(105.7): 14 B-trim: 481 in 2/49 Lambda= 0.159540 statistics sampled from 8561 (8569) to 8561 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.263), width: 16 Scan time: 3.350 The best scores are: opt bits E(32554) CCDS1102.1 GBA gene_id:2629|Hs108|chr1 ( 536) 3670 853.7 0 CCDS53373.1 GBA gene_id:2629|Hs108|chr1 ( 449) 3069 715.4 3.6e-206 CCDS53374.1 GBA gene_id:2629|Hs108|chr1 ( 487) 2661 621.5 7.1e-178 >>CCDS1102.1 GBA gene_id:2629|Hs108|chr1 (536 aa) initn: 3670 init1: 3670 opt: 3670 Z-score: 4561.4 bits: 853.7 E(32554): 0 Smith-Waterman score: 3670; 100.0% identity (100.0% similar) in 536 aa overlap (1-536:1-536) 10 20 30 40 50 60 pF1KB3 MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 NLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQK 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 NDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ 490 500 510 520 530 >>CCDS53373.1 GBA gene_id:2629|Hs108|chr1 (449 aa) initn: 3069 init1: 3069 opt: 3069 Z-score: 3815.0 bits: 715.4 E(32554): 3.6e-206 Smith-Waterman score: 3069; 100.0% identity (100.0% similar) in 449 aa overlap (88-536:1-449) 60 70 80 90 100 110 pF1KB3 NATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKV :::::::::::::::::::::::::::::: CCDS53 MELSMGPIQANHTGTGLLLTLQPEQKFQKV 10 20 30 120 130 140 150 160 170 pF1KB3 KGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADT 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 PDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLK 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 GQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRD 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB3 FIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLA 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 PAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGW 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 TDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVA 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB3 SQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ 400 410 420 430 440 >>CCDS53374.1 GBA gene_id:2629|Hs108|chr1 (487 aa) initn: 2661 init1: 2661 opt: 2661 Z-score: 3306.9 bits: 621.5 E(32554): 7.1e-178 Smith-Waterman score: 3254; 90.9% identity (90.9% similar) in 536 aa overlap (1-536:1-487) 10 20 30 40 50 60 pF1KB3 MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGF ::::::::::::::::::::::::::::::::::::::::::: CCDS53 YCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTG----------------- 70 80 90 100 130 140 150 160 170 180 pF1KB3 GGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDD :::::::::::::::::::::::::::: CCDS53 --------------------------------IGYNIIRVPMASCDFSIRTYTYADTPDD 110 120 130 190 200 210 220 230 240 pF1KB3 FQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQP 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB3 GDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIA 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB3 RDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 RDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAK 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 ATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDW 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 NLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQK 380 390 400 410 420 430 490 500 510 520 530 pF1KB3 NDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ 440 450 460 470 480 536 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:17:41 2016 done: Sat Nov 5 12:17:41 2016 Total Scan time: 3.350 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]