FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3590, 131 aa 1>>>pF1KB3590 131 - 131 aa - 131 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6916+/-0.000311; mu= 14.4320+/- 0.019 mean_var=60.3012+/-11.918, 0's: 0 Z-trim(117.2): 39 B-trim: 0 in 0/50 Lambda= 0.165162 statistics sampled from 28935 (28974) to 28935 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.34), width: 16 Scan time: 4.230 The best scores are: opt bits E(85289) NP_001120685 (OMIM: 601384) lymphocyte antigen 6E ( 131) 880 217.3 5.8e-57 NP_002337 (OMIM: 601384) lymphocyte antigen 6E pre ( 131) 880 217.3 5.8e-57 NP_002338 (OMIM: 603625) lymphocyte antigen 6H iso ( 140) 204 56.2 1.9e-08 XP_016868903 (OMIM: 603625) PREDICTED: lymphocyte ( 140) 204 56.2 1.9e-08 NP_001129127 (OMIM: 603625) lymphocyte antigen 6H ( 161) 204 56.2 2.1e-08 NP_001123950 (OMIM: 603625) lymphocyte antigen 6H ( 161) 204 56.2 2.1e-08 XP_016868902 (OMIM: 603625) PREDICTED: lymphocyte ( 166) 204 56.3 2.2e-08 NP_005663 (OMIM: 602470) prostate stem cell antige ( 114) 196 54.2 6e-08 NP_803430 (OMIM: 606110) ly-6/neurotoxin-like prot ( 116) 168 47.6 6.2e-06 NP_803252 (OMIM: 606110) ly-6/neurotoxin-like prot ( 116) 168 47.6 6.2e-06 NP_803429 (OMIM: 606110) ly-6/neurotoxin-like prot ( 116) 168 47.6 6.2e-06 NP_003686 (OMIM: 606204) lymphocyte antigen 6D pre ( 128) 157 45.0 4.1e-05 NP_065160 (OMIM: 248300,606119) secreted Ly-6/uPAR ( 103) 141 41.1 0.00049 NP_803253 (OMIM: 606110) ly-6/neurotoxin-like prot ( 97) 136 39.9 0.0011 >>NP_001120685 (OMIM: 601384) lymphocyte antigen 6E prec (131 aa) initn: 880 init1: 880 opt: 880 Z-score: 1143.6 bits: 217.3 E(85289): 5.8e-57 Smith-Waterman score: 880; 100.0% identity (100.0% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 VTFGHSLSKTCSPACPIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFGHSLSKTCSPACPIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLL 70 80 90 100 110 120 130 pF1KB3 SLLPALLRFGP ::::::::::: NP_001 SLLPALLRFGP 130 >>NP_002337 (OMIM: 601384) lymphocyte antigen 6E precurs (131 aa) initn: 880 init1: 880 opt: 880 Z-score: 1143.6 bits: 217.3 E(85289): 5.8e-57 Smith-Waterman score: 880; 100.0% identity (100.0% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 VTFGHSLSKTCSPACPIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTFGHSLSKTCSPACPIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLL 70 80 90 100 110 120 130 pF1KB3 SLLPALLRFGP ::::::::::: NP_002 SLLPALLRFGP 130 >>NP_002338 (OMIM: 603625) lymphocyte antigen 6H isoform (140 aa) initn: 161 init1: 71 opt: 204 Z-score: 272.7 bits: 56.2 E(85289): 1.9e-08 Smith-Waterman score: 204; 32.6% identity (56.7% similar) in 141 aa overlap (1-131:6-140) 10 20 30 40 50 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASA :: . .:::.:: : .: : .: .. .: : :. .:. :..: . NP_002 MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCT-PKQCQPSDTVCASVRITD 10 20 30 40 50 60 70 80 90 100 pF1KB3 GIGNLVTFGHSLSKTCSPACPIPE---------G-VNVGVASMGISCCQSFLCNFSAADG .. ::..: :. .: . . : .: :. .. ..::.. ::: .:. : NP_002 PSSS--RKDHSVNKMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGAAGAG 60 70 80 90 100 110 110 120 130 pF1KB3 GLRASVTLLGAGLLLSLLPALLRFGP : :..:::::: :::: :: NP_002 H---SPWALAGGLLLSLGPALLWAGP 120 130 140 >>XP_016868903 (OMIM: 603625) PREDICTED: lymphocyte anti (140 aa) initn: 161 init1: 71 opt: 204 Z-score: 272.7 bits: 56.2 E(85289): 1.9e-08 Smith-Waterman score: 204; 32.6% identity (56.7% similar) in 141 aa overlap (1-131:6-140) 10 20 30 40 50 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASA :: . .:::.:: : .: : .: .. .: : :. .:. :..: . XP_016 MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCT-PKQCQPSDTVCASVRITD 10 20 30 40 50 60 70 80 90 100 pF1KB3 GIGNLVTFGHSLSKTCSPACPIPE---------G-VNVGVASMGISCCQSFLCNFSAADG .. ::..: :. .: . . : .: :. .. ..::.. ::: .:. : XP_016 PSSS--RKDHSVNKMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGAAGAG 60 70 80 90 100 110 110 120 130 pF1KB3 GLRASVTLLGAGLLLSLLPALLRFGP : :..:::::: :::: :: XP_016 H---SPWALAGGLLLSLGPALLWAGP 120 130 140 >>NP_001129127 (OMIM: 603625) lymphocyte antigen 6H isof (161 aa) initn: 148 init1: 71 opt: 204 Z-score: 271.8 bits: 56.2 E(85289): 2.1e-08 Smith-Waterman score: 204; 32.6% identity (56.7% similar) in 141 aa overlap (1-131:27-161) 10 20 30 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLY :: . .:::.:: : .: : .: .. . NP_001 MLAPQRTRAPSPRAAPRPTRSMLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSH 10 20 30 40 50 60 40 50 60 70 80 pF1KB3 CLKPTICSDQDNYCVTVSASAGIGNLVTFGHSLSKTCSPACPIPE---------G-VNVG : : :. .:. :..: . .. ::..: :. .: . . : .: : NP_001 CT-PKQCQPSDTVCASVRITDPSSS--RKDHSVNKMCASSCDFVKRHFFSDYLMGFINSG 70 80 90 100 110 90 100 110 120 130 pF1KB3 VASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLLSLLPALLRFGP . .. ..::.. ::: .:. : : :..:::::: :::: :: NP_001 ILKVDVDCCEKDLCNGAAGAGH---SPWALAGGLLLSLGPALLWAGP 120 130 140 150 160 >>NP_001123950 (OMIM: 603625) lymphocyte antigen 6H isof (161 aa) initn: 148 init1: 71 opt: 204 Z-score: 271.8 bits: 56.2 E(85289): 2.1e-08 Smith-Waterman score: 204; 32.6% identity (56.7% similar) in 141 aa overlap (1-131:27-161) 10 20 30 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLY :: . .:::.:: : .: : .: .. . NP_001 MLAPQRTRAPSPRAAPRPTRSMLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSH 10 20 30 40 50 60 40 50 60 70 80 pF1KB3 CLKPTICSDQDNYCVTVSASAGIGNLVTFGHSLSKTCSPACPIPE---------G-VNVG : : :. .:. :..: . .. ::..: :. .: . . : .: : NP_001 CT-PKQCQPSDTVCASVRITDPSSS--RKDHSVNKMCASSCDFVKRHFFSDYLMGFINSG 70 80 90 100 110 90 100 110 120 130 pF1KB3 VASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLLSLLPALLRFGP . .. ..::.. ::: .:. : : :..:::::: :::: :: NP_001 ILKVDVDCCEKDLCNGAAGAGH---SPWALAGGLLLSLGPALLWAGP 120 130 140 150 160 >>XP_016868902 (OMIM: 603625) PREDICTED: lymphocyte anti (166 aa) initn: 148 init1: 71 opt: 204 Z-score: 271.7 bits: 56.3 E(85289): 2.2e-08 Smith-Waterman score: 204; 32.6% identity (56.7% similar) in 141 aa overlap (1-131:32-166) 10 20 30 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQK :: . .:::.:: : .: : .: XP_016 LLPSRLAPQRTRAPSPRAAPRPTRSMLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTT 10 20 30 40 50 60 40 50 60 70 80 pF1KB3 SNLYCLKPTICSDQDNYCVTVSASAGIGNLVTFGHSLSKTCSPACPIPE---------G- .. .: : :. .:. :..: . .. ::..: :. .: . . : XP_016 NSSHCT-PKQCQPSDTVCASVRITDPSSS--RKDHSVNKMCASSCDFVKRHFFSDYLMGF 70 80 90 100 110 90 100 110 120 130 pF1KB3 VNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLLSLLPALLRFGP .: :. .. ..::.. ::: .:. : : :..:::::: :::: :: XP_016 INSGILKVDVDCCEKDLCNGAAGAGH---SPWALAGGLLLSLGPALLWAGP 120 130 140 150 160 >>NP_005663 (OMIM: 602470) prostate stem cell antigen pr (114 aa) initn: 138 init1: 65 opt: 196 Z-score: 263.6 bits: 54.2 E(85289): 6e-08 Smith-Waterman score: 196; 34.1% identity (61.0% similar) in 123 aa overlap (11-131:2-111) 10 20 30 40 50 60 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL : :... ...:.:.:: : :: ::. :.. . : :. : .: : NP_005 MAGLALQPGTALLCYSCKAQVSNEDCLQVENCTQLGEQCWTARIRA-VGLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 VTFGHSLSKTCSPACPIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGLLL .. .:: :: : . .. . :.. .:.::.. ::: :.: . : :. .: NP_005 TV----ISKGCSLNC-VDDSQDYYVGKKNITCCDTDLCNASGAHA-------LQPAAAIL 60 70 80 90 130 pF1KB3 SLLPAL--LRFGP .::::: : .:: NP_005 ALLPALGLLLWGPGQL 100 110 >>NP_803430 (OMIM: 606110) ly-6/neurotoxin-like protein (116 aa) initn: 122 init1: 73 opt: 168 Z-score: 227.5 bits: 47.6 E(85289): 6.2e-06 Smith-Waterman score: 168; 30.2% identity (55.8% similar) in 129 aa overlap (1-127:1-116) 10 20 30 40 50 60 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL : .: ..:..:.:. :..: : : . .: :..: : . ::.:. . . NP_803 MTPLLTLILVVLMGLPLAQALDCHVCAYNGDN--CFNPMRCPAMVAYCMTTRTYYTPTRM 10 20 30 40 50 70 80 90 100 110 pF1KB3 VTFGHSLSKTCSPAC--PIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGL ..::.: : : . .: . ... :::: ::: . :: . .:: : . NP_803 -----KVSKSCVPRCFETVYDGYSKHAST--TSCCQYDLCNGT----GLATPATLALAPI 60 70 80 90 100 120 130 pF1KB3 LLSLLPALLRFGP ::. : .:: NP_803 LLATLWGLL 110 >>NP_803252 (OMIM: 606110) ly-6/neurotoxin-like protein (116 aa) initn: 122 init1: 73 opt: 168 Z-score: 227.5 bits: 47.6 E(85289): 6.2e-06 Smith-Waterman score: 168; 30.2% identity (55.8% similar) in 129 aa overlap (1-127:1-116) 10 20 30 40 50 60 pF1KB3 MKIFLPVLLAALLGVERASSLMCFSCLNQKSNLYCLKPTICSDQDNYCVTVSASAGIGNL : .: ..:..:.:. :..: : : . .: :..: : . ::.:. . . NP_803 MTPLLTLILVVLMGLPLAQALDCHVCAYNGDN--CFNPMRCPAMVAYCMTTRTYYTPTRM 10 20 30 40 50 70 80 90 100 110 pF1KB3 VTFGHSLSKTCSPAC--PIPEGVNVGVASMGISCCQSFLCNFSAADGGLRASVTLLGAGL ..::.: : : . .: . ... :::: ::: . :: . .:: : . NP_803 -----KVSKSCVPRCFETVYDGYSKHAST--TSCCQYDLCNGT----GLATPATLALAPI 60 70 80 90 100 120 130 pF1KB3 LLSLLPALLRFGP ::. : .:: NP_803 LLATLWGLL 110 131 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:13:03 2016 done: Sat Nov 5 05:13:04 2016 Total Scan time: 4.230 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]