Result of FASTA (omim) for
pF1KB3598
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3598, 1499 aa
1>>>pF1KB3598 1499 - 1499 aa - 1499 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.1110+/-0.000621; mu= -5.7408+/- 0.039
mean_var=840.5928+/-174.105, 0's: 0 Z-trim(122.2): 723 B-trim: 0 in 0/59
Lambda= 0.044237
statistics sampled from 39078 (39875) to 39078 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.468), width: 16
Scan time: 19.530
The best scores are: opt bits E(85289)
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 11157 729.3 5.5e-209
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 10854 710.0 3.5e-203
XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 7278 481.8 1.8e-134
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 7276 481.6 2e-134
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 7272 481.4 2.4e-134
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 6965 461.7 1.8e-128
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 6965 461.8 1.8e-128
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 6581 437.2 4.1e-121
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 6194 412.6 1.2e-113
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 5609 375.2 2.1e-102
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 5566 372.5 1.4e-101
NP_000080 (OMIM: 120160,130060,166210,166220,16671 (1366) 4613 311.6 2.7e-83
XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 4509 304.9 2.5e-81
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 4384 297.0 6.8e-79
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 4381 297.0 9.3e-79
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 4379 296.9 1e-78
NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 4366 296.0 1.8e-78
NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 4366 296.0 1.8e-78
NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 4366 296.0 1.8e-78
XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 4366 296.0 1.8e-78
XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 4366 296.0 1.8e-78
NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 4358 295.5 2.4e-78
XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 4087 278.0 3.4e-73
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 4077 277.6 6.2e-73
XP_011512601 (OMIM: 120290,184840,215150,277610,60 (1498) 3918 267.3 6.5e-70
XP_011512602 (OMIM: 120290,184840,215150,277610,60 (1438) 3917 267.2 6.6e-70
NP_542410 (OMIM: 120290,184840,215150,277610,60186 (1629) 3918 267.4 6.8e-70
NP_542411 (OMIM: 120290,184840,215150,277610,60186 (1736) 3918 267.4 7e-70
XP_016865739 (OMIM: 120290,184840,215150,277610,60 (1736) 3918 267.4 7e-70
NP_542412 (OMIM: 120290,184840,215150,277610,60186 (1650) 3917 267.3 7.1e-70
XP_011512604 (OMIM: 120290,184840,215150,277610,60 (1365) 3910 266.8 8.7e-70
XP_016865740 (OMIM: 120290,184840,215150,277610,60 (1342) 3863 263.7 6.9e-69
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 3620 248.4 3.7e-64
NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 3620 248.4 3.7e-64
XP_016855825 (OMIM: 120280,154780,228520,603932,60 (1515) 3422 235.7 2.2e-60
XP_011517440 (OMIM: 608461,615155) PREDICTED: coll (1858) 3127 217.0 1.2e-54
NP_116277 (OMIM: 608461,615155) collagen alpha-1(X (1860) 3127 217.0 1.2e-54
XP_016858786 (OMIM: 120131,203780) PREDICTED: coll (1651) 3061 212.7 2e-53
XP_011519350 (OMIM: 120130,175780,180000,607595,61 (1605) 3049 211.9 3.3e-53
NP_001836 (OMIM: 120130,175780,180000,607595,61177 (1669) 3049 211.9 3.4e-53
XP_011508871 (OMIM: 120131,203780) PREDICTED: coll (1414) 3039 211.2 4.8e-53
XP_011508872 (OMIM: 120131,203780) PREDICTED: coll (1414) 3039 211.2 4.8e-53
XP_016858789 (OMIM: 120131,203780) PREDICTED: coll (1414) 3039 211.2 4.8e-53
XP_011508870 (OMIM: 120131,203780) PREDICTED: coll (1419) 3039 211.2 4.8e-53
XP_011508869 (OMIM: 120131,203780) PREDICTED: coll (1420) 3039 211.2 4.8e-53
XP_011508868 (OMIM: 120131,203780) PREDICTED: coll (1420) 3039 211.2 4.8e-53
XP_011508867 (OMIM: 120131,203780) PREDICTED: coll (1424) 3039 211.2 4.8e-53
XP_011508858 (OMIM: 104200,120070,141200,203780) P (1257) 2960 206.1 1.5e-51
XP_011508860 (OMIM: 120131,203780) PREDICTED: coll (1654) 2878 201.0 6.5e-50
NP_001837 (OMIM: 120090,614483,614519) collagen al (1712) 2862 200.0 1.4e-49
>>NP_000384 (OMIM: 120190,130000) collagen alpha-2(V) ch (1499 aa)
initn: 11157 init1: 11157 opt: 11157 Z-score: 3873.0 bits: 729.3 E(85289): 5.5e-209
Smith-Waterman score: 11157; 100.0% identity (100.0% similar) in 1499 aa overlap (1-1499:1-1499)
10 20 30 40 50 60
pF1KB3 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 HRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 PPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 GIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 PPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 VRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 KNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB3 EDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB3 NTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIR
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490
pF1KB3 FRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
1450 1460 1470 1480 1490
>>XP_011508875 (OMIM: 120190,130000) PREDICTED: collagen (1453 aa)
initn: 10854 init1: 10854 opt: 10854 Z-score: 3768.6 bits: 710.0 E(85289): 3.5e-203
Smith-Waterman score: 10854; 100.0% identity (100.0% similar) in 1453 aa overlap (47-1499:1-1453)
20 30 40 50 60 70
pF1KB3 LLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIEC
::::::::::::::::::::::::::::::
XP_011 MYLNRDIWKPAPCQICVCDNGAILCDKIEC
10 20 30
80 90 100 110 120 130
pF1KB3 QDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 PGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 GLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGP
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 EGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGA
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB3 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB3 SGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB3 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB3 PGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB3 QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB3 PGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB3 QGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB3 HGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGA
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB3 RGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB3 PGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGR
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB3 VGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQ
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KB3 PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KB3 PGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KB3 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KB3 PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGE
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KB3 PGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLS
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KB3 SQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETC
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KB3 ISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAITQMTFLRLLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAITQMTFLRLLSKE
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KB3 ASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGN
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490
pF1KB3 VGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
:::::::::::::::::::::::::::::::::::::::::::
XP_011 VGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
1420 1430 1440 1450
>>XP_016874318 (OMIM: 108300,120140,132450,150600,151210 (1534 aa)
initn: 9564 init1: 6185 opt: 7278 Z-score: 2535.0 bits: 481.8 E(85289): 1.8e-134
Smith-Waterman score: 7280; 65.1% identity (79.0% similar) in 1503 aa overlap (5-1499:48-1534)
10 20 30
pF1KB3 MMANWAEAR--PLLILIVLLGQFVSIKAQEEDED
: :. :.:..:: : .. : .: .
XP_016 YRSKGRSVWGRFLPGMKGGTGDQEKRPAKPWEEGSLAKTLVLLTLLVAAV-LRCQGQDVQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 EGYGEEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPGEC
:. : .:.:.:: : ..:.::: ::.:::::.:..::: : :.:: :: .: : :::
XP_016 EA-G---SCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 CPVCSQTPGGGNTNFGR-GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR
::.: : : :. : :::::::: . ..: .: ::: :: : :::::.:: ::.
XP_016 CPIC---PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE
140 150 160 170 180
160 170 180 190 200 210
pF1KB3 PGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG-LDEKSGLGSQVGL
: ::.: :::::.::.:: ::::: : ::: ::. :.::::: .:::.: :.:.:.
XP_016 KGAPGPRGRDGEPGTPGNPGPPGPPG-P--PGPPGLGGNFAAQMAGGFDEKAG-GAQLGV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG
: : .::.::::: : : : : : :::::.:: ::.: ::: :::::::.::: :
XP_016 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG
. :. :: : : :::::::.:::::.:::::. ::.: :::.:::: :::.: : :
XP_016 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG
. ::.::::.:::::: :: :: : :: :.:: :: ::.: :. :::: :: :::::
XP_016 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG
::::::::: :: ::: : :: : : : :::: ::::: .:.:: .: :: :: :
XP_016 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB3 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG
:::::.::: : .:: :.::. ::::: :::::::: : :: :: ::::::: ::.::
XP_016 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB3 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG
::: :: :::::::::::::.::: ::::: ::::: : .::::..:::::::::::::
XP_016 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB3 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG
:::::: :: ::.::.:: ::::::::::::: : ::::: ::.:::::..:.::: :
XP_016 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB3 EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGG
: : :.:: :: ::::::.: .:: :: : :::::::: :::.::::::::::::::::
XP_016 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB3 KPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG
:::::::::. :: : .::::::: ::::: :: :: : .:. : : :::::. ::.:
XP_016 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB3 TPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG
:: ::::::::::::: :: ::::::: .:::: ::. :.::.::: ::.:::::::
XP_016 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB3 PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG
.::::: :: : .: :.:: :: :::.:: : .::::: : :::::.::: :: ::::
XP_016 ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG
850 860 870 880 890 900
880 890 900 910 920 930
pF1KB3 DAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG
:::.::::: .:.:::.::.:: : ::.::.:::::::::::.:::::::: : ::: :
XP_016 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG
910 920 930 940 950 960
940 950 960 970 980 990
pF1KB3 PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG
: : ::.:: : ::: : ::.:. : :: : ::.::.::.:: : .::::: : .:
XP_016 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB3 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG
::::::.::::::::.::::::.: ::: : ::.::.:::::::::: .::.:::: ::
XP_016 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB3 PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG
: :: ::::::.: .::::. : .: ::. : ::.:::.: : :.::. :..::.:
XP_016 SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMG
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB3 PPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPG
: : :: ::. ::::::::::. :. :.:: ::::::::::::::::::.:.::..: :
XP_016 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220
pF1KB3 PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG---
: ::::::::::::::.: : ::::::: :: ::.:: ::::.:::::::::::
XP_016 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGI
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KB3 HLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDG
..: : .: :. :::: . :::: . . : : ::::::..:::..:::.:
XP_016 DMSAFAG--LGPR-EKGPDPLQYMRADQAAGGLR-QHDAEVDATLKSLNNQIESIRSPEG
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KB3 SKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRK
:.:.::::: :::::: .::.:::::::: . ::.::.:::::::::. ::..::.:
XP_016 SRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKK
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KB3 TWWASKSPDNKPVWYGLDMNRGSQFAYGDHQ-SPNTAITQMTFLRLLSKEASQNITYICK
.::.::: ..: .:.: .: : .:.::: . .:::: .::::::::: :.:::::: ::
XP_016 NWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCK
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KB3 NSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRT
::..:.:. : :::::....:.::..:.:::: :: : .:.: :.:..:. ::::.:::.
XP_016 NSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRS
1450 1460 1470 1480 1490 1500
1470 1480 1490
pF1KB3 QNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
:...::::::.::.:.:: .:::::.::::::.
XP_016 QKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
1510 1520 1530
>>XP_016874317 (OMIM: 108300,120140,132450,150600,151210 (1535 aa)
initn: 9564 init1: 6185 opt: 7276 Z-score: 2534.3 bits: 481.6 E(85289): 2e-134
Smith-Waterman score: 7278; 65.0% identity (79.1% similar) in 1502 aa overlap (5-1499:48-1535)
10 20 30
pF1KB3 MMANWAEAR--PLLILIVLLGQFVSIKAQEEDED
: :. :.:..:: : .. : .: .
XP_016 YRSKGRSVWGRFLPGMKGGTGDQEKRPAKPWEEGSLAKTLVLLTLLVAAV-LRCQGQDVQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 EGYGEEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPGEC
:. : .:.:.:: : ..:.::: ::.:::::.:..::: : :.:: :: .: : :::
XP_016 EA-G---SCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 CPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRP
::.: : . ... : :::::::: . ..: .: ::: :: : :::::.:: ::.
XP_016 CPICP-TDLATASGWQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEK
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 GPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG-LDEKSGLGSQVGLM
: ::.: :::::.::.:: ::::: : ::: ::. :.::::: .:::.: :.:.:.:
XP_016 GAPGPRGRDGEPGTPGNPGPPGPPG-P--PGPPGLGGNFAAQMAGGFDEKAG-GAQLGVM
200 210 220 230 240
220 230 240 250 260 270
pF1KB3 PGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGR
: .::.::::: : : : : : :::::.:: ::.: ::: :::::::.::: :.
XP_016 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 NGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGA
:. :: : : :::::::.:::::.:::::. ::.: :::.:::: :::.: : :.
XP_016 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 MGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGP
::.::::.:::::: :: :: : :: :.:: :: ::.: :. :::: :: ::::::
XP_016 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 TGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGS
:::::::: :: ::: : :: : : : :::: ::::: .:.:: .: :: :: :
XP_016 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB3 PGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGT
:::::.::: : .:: :.::. ::::: :::::::: : :: :: ::::::: ::.::
XP_016 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB3 VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGA
::: :: :::::::::::::.::: ::::: ::::: : .::::..::::::::::::::
XP_016 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB3 RGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGE
::::: :: ::.::.:: ::::::::::::: : ::::: ::.:::::..:.::: ::
XP_016 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB3 AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK
: :.:: :: ::::::.: .:: :: : :::::::: :::.:::::::::::::::::
XP_016 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB3 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT
::::::::. :: : .::::::: ::::: :: :: : .:. : : :::::. ::.:
XP_016 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB3 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP
:: ::::::::::::: :: ::::::: .:::: ::. :.::.::: ::.:::::::
XP_016 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB3 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD
.::::: :: : .: :.:: :: :::.:: : .::::: : :::::.::: :: :::::
XP_016 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KB3 AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP
::.::::: .:.:::.::.:: : ::.::.:::::::::::.:::::::: : ::: ::
XP_016 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP
910 920 930 940 950 960
940 950 960 970 980 990
pF1KB3 LGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ
: ::.:: : ::: : ::.:. : :: : ::.::.::.:: : .::::: : .::
XP_016 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB3 RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP
:::::.::::::::.::::::.: ::: : ::.::.:::::::::: .::.:::: ::
XP_016 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB3 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP
: :: ::::::.: .::::. : .: ::. : ::.:::.: : :.::. :..::.::
XP_016 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB3 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP
: :: ::. ::::::::::. :. :.:: ::::::::::::::::::.:.::..: ::
XP_016 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220
pF1KB3 FGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG---H
::::::::::::::.: : ::::::: :: ::.:: ::::.:::::::::::
XP_016 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGID
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KB3 LTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGS
..: : .: :. :::: . :::: . . : : ::::::..:::..:::.::
XP_016 MSAFAG--LGPR-EKGPDPLQYMRADQAAGGLR-QHDAEVDATLKSLNNQIESIRSPEGS
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KB3 KKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKT
.:.::::: :::::: .::.:::::::: . ::.::.:::::::::. ::..::.:.
XP_016 RKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKN
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KB3 WWASKSPDNKPVWYGLDMNRGSQFAYGDHQ-SPNTAITQMTFLRLLSKEASQNITYICKN
::.::: ..: .:.: .: : .:.::: . .:::: .::::::::: :.:::::: :::
XP_016 WWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKN
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KB3 SVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQ
:..:.:. : :::::....:.::..:.:::: :: : .:.: :.:..:. ::::.:::.:
XP_016 SIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQ
1450 1460 1470 1480 1490 1500
1470 1480 1490
pF1KB3 NVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
...::::::.::.:.:: .:::::.::::::.
XP_016 KTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
1510 1520 1530
>>NP_001835 (OMIM: 108300,120140,132450,150600,151210,15 (1487 aa)
initn: 9564 init1: 6185 opt: 7272 Z-score: 2533.1 bits: 481.4 E(85289): 2.4e-134
Smith-Waterman score: 7277; 65.3% identity (79.4% similar) in 1494 aa overlap (12-1499:10-1487)
10 20 30 40 50 60
pF1KB3 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQ
:.:..:: : .. : .: .:. : .:.:.:: : ..:.::: ::.
NP_001 MIRLGAPQTLVLLTLLVAAV-LRCQGQDVQEA-G---SCVQDGQRYNDKDVWKPEPCR
10 20 30 40 50
70 80 90 100 110
pF1KB3 ICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGR-GRKGQKGEPG
:::::.:..::: : :.:: :: .: : :::::.: : : :. : ::::::::
NP_001 ICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPIC---PTDLATASGQPGPKGQKGEPG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 LVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHP
. ..: .: ::: :: : :::::.:: ::. : ::.: :::::.::.:: ::::: :
NP_001 DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG-P
120 130 140 150 160
180 190 200 210 220 230
pF1KB3 SHPGPDGLSRPFSAQMAG-LDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGP
::: ::. :.::::: .:::.: :.:.:.: : .::.::::: : : : : :
NP_001 --PGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB3 PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL
:::::.:: ::.: ::: :::::::.::: :. :. :: : : :::::::.:::::.
NP_001 PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 KGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGA
:::::. ::.: :::.:::: :::.: : :. ::.::::.:::::: :: :: : ::
NP_001 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB3 HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGL
:.:: :: ::.: :. :::: :: :::::::::::::: :: ::: : :: : :
NP_001 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB3 PGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGE
: :::: ::::: .:.:: .: :: :: : :::::.::: : .:: :.::. :::::
NP_001 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB3 AGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP
:::::::: : :: :: ::::::: ::.:: ::: :: :::::::::::::.::: ::
NP_001 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP
470 480 490 500 510 520
540 550 560 570 580 590
pF1KB3 KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGR
::: ::::: : .::::..::::::::::::::::::: :: ::.::.:: ::::::::
NP_001 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR
530 540 550 560 570 580
600 610 620 630 640 650
pF1KB3 PGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP
::::: : ::::: ::.:::::..:.::: :: : :.:: :: ::::::.: .:: ::
NP_001 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP
590 600 610 620 630 640
660 670 680 690 700 710
pF1KB3 PGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE
: :::::::: :::.:::::::::::::::::::::::::. :: : .::::::: :::
NP_001 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE
650 660 670 680 690 700
720 730 740 750 760 770
pF1KB3 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD
:: :: :: : .:. : : :::::. ::.: :: ::::::::::::: :: :::::
NP_001 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD
710 720 730 740 750 760
780 790 800 810 820 830
pF1KB3 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE
:: .:::: ::. :.::.::: ::.::::::: .::::: :: : .: :.:: :: :::
NP_001 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE
770 780 790 800 810 820
840 850 860 870 880 890
pF1KB3 NGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGG
.:: : .::::: : :::::.::: :: :::::::.::::: .:.:::.::.:: : ::.
NP_001 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA
830 840 850 860 870 880
900 910 920 930 940 950
pF1KB3 RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP
::.:::::::::::.:::::::: : ::: :: : ::.:: : ::: : ::.:. :
NP_001 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KB3 AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK
:: : ::.::.::.:: : .::::: : .:::::::.::::::::.::::::.: :::
NP_001 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KB3 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL
: ::.::.:::::::::: .::.:::: :: : :: ::::::.: .::::. : .:
NP_001 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KB3 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGD
::. : ::.:::.: : :.::. :..::.:: : :: ::. ::::::::::. :. :.
NP_001 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KB3 RGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGP
:: ::::::::::::::::::.:.::..: :: ::::::::::::::.: : :::::
NP_001 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KB3 PGVRGSVGEAGPEGPPGEPGPPGPPGPPG---HLTAALGDIMGHYDESMPDPLPEFTEDQ
:: :: ::.:: ::::.::::::::::: ..: : .: ... :::: . ::
NP_001 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAG--LGPREKG-PDPLQYMRADQ
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KB3 AAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDP
:: ... : : ::::::..:::..:::.::.:.::::: :::::: .::.:::::
NP_001 AAGGLRQH-DAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDP
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KB3 NQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYG
::: . ::.::.:::::::::. ::..::.:.::.::: ..: .:.: .: : .:.::
NP_001 NQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYG
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KB3 DHQ-SPNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIK
: . .:::: .::::::::: :.:::::: ::::..:.:. : :::::....:.::..:.
NP_001 DDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIR
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KB3 AEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIG
:::: :: : .:.: :.:..:. ::::.:::.:...::::::.::.:.:: .:::::.::
NP_001 AEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIG
1430 1440 1450 1460 1470 1480
pF1KB3 PVCFV
::::.
NP_001 PVCFL
>>NP_149162 (OMIM: 108300,120140,132450,150600,151210,15 (1418 aa)
initn: 9564 init1: 6185 opt: 6965 Z-score: 2427.4 bits: 461.7 E(85289): 1.8e-128
Smith-Waterman score: 6965; 66.7% identity (80.1% similar) in 1395 aa overlap (110-1499:32-1418)
80 90 100 110 120 130
pF1KB3 LDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGS
: :::::::: . ..: .: ::: :: :
NP_149 IRLGAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGE
10 20 30 40 50 60
140 150 160 170 180 190
pF1KB3 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG-L
:::::.:: ::. : ::.: :::::.::.:: ::::: : ::: ::. :.::::: .
NP_149 QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG-P--PGPPGLGGNFAAQMAGGF
70 80 90 100 110
200 210 220 230 240 250
pF1KB3 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG
:::.: :.:.:.: : .::.::::: : : : : : :::::.:: ::.: ::: :
NP_149 DEKAG-GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB3 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG
::::::.::: :. :. :: : : :::::::.:::::.:::::. ::.: :::.::::
NP_149 PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB3 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG
:::.: : :. ::.::::.:::::: :: :: : :: :.:: :: ::.: :. :
NP_149 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB3 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPG
::: :: :::::::::::::: :: ::: : :: : : : :::: ::::: .:.::
NP_149 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG
300 310 320 330 340 350
440 450 460 470 480 490
pF1KB3 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG
.: :: :: : :::::.::: : .:: :.::. ::::: :::::::: : :: :: :
NP_149 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG
360 370 380 390 400 410
500 510 520 530 540 550
pF1KB3 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQG
:::::: ::.:: ::: :: :::::::::::::.::: ::::: ::::: : .::::..:
NP_149 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG
420 430 440 450 460 470
560 570 580 590 600 610
pF1KB3 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPG
:::::::::::::::::: :: ::.::.:: ::::::::::::: : ::::: ::.::
NP_149 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG
480 490 500 510 520 530
620 630 640 650 660 670
pF1KB3 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG
:::..:.::: :: : :.:: :: ::::::.: .:: :: : :::::::: :::.::::
NP_149 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG
540 550 560 570 580 590
680 690 700 710 720 730
pF1KB3 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG
:::::::::::::::::::::. :: : .::::::: ::::: :: :: : .:. : :
NP_149 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG
600 610 620 630 640 650
740 750 760 770 780 790
pF1KB3 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG
:::::. ::.: :: ::::::::::::: :: ::::::: .:::: ::. :.::.::
NP_149 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG
660 670 680 690 700 710
800 810 820 830 840 850
pF1KB3 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPG
: ::.::::::: .::::: :: : .: :.:: :: :::.:: : .::::: : :::::
NP_149 LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG
720 730 740 750 760 770
860 870 880 890 900 910
pF1KB3 VKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG
.::: :: :::::::.::::: .:.:::.::.:: : ::.::.:::::::::::.:::::
NP_149 AKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG
780 790 800 810 820 830
920 930 940 950 960 970
pF1KB3 PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG
::: : ::: :: : ::.:: : ::: : ::.:. : :: : ::.::.::.:: :
NP_149 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG
840 850 860 870 880 890
980 990 1000 1010 1020 1030
pF1KB3 PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG
.::::: : .:::::::.::::::::.::::::.: ::: : ::.::.::::::::::
NP_149 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG
900 910 920 930 940 950
1040 1050 1060 1070 1080 1090
pF1KB3 SNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG
.::.:::: :: : :: ::::::.: .::::. : .: ::. : ::.:::.: : :
NP_149 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG
960 970 980 990 1000 1010
1100 1110 1120 1130 1140 1150
pF1KB3 QRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPG
.::. :..::.:: : :: ::. ::::::::::. :. :.:: :::::::::::::::::
NP_149 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG
1020 1030 1040 1050 1060 1070
1160 1170 1180 1190 1200 1210
pF1KB3 PNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPG
:.:.::..: :: ::::::::::::::.: : ::::::: :: ::.:: ::::.::
NP_149 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG
1080 1090 1100 1110 1120 1130
1220 1230 1240 1250 1260 1270
pF1KB3 PPGPPGPPG---HLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSL
::::::::: ..: : .: ... :::: . :::: . . : : ::::::
NP_149 PPGPPGPPGPGIDMSAFAG--LGPREKG-PDPLQYMRADQAAGGLR-QHDAEVDATLKSL
1140 1150 1160 1170 1180 1190
1280 1290 1300 1310 1320 1330
pF1KB3 SSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGET
..:::..:::.::.:.::::: :::::: .::.:::::::: . ::.::.::::::::
NP_149 NNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGET
1200 1210 1220 1230 1240 1250
1340 1350 1360 1370 1380 1390
pF1KB3 CISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQ-SPNTAITQMTFLRLLS
:. ::..::.:.::.::: ..: .:.: .: : .:.::: . .:::: .:::::::::
NP_149 CVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLS
1260 1270 1280 1290 1300 1310
1400 1410 1420 1430 1440 1450
pF1KB3 KEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRN
:.:::::: ::::..:.:. : :::::....:.::..:.:::: :: : .:.: :.:..
NP_149 TEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHT
1320 1330 1340 1350 1360 1370
1460 1470 1480 1490
pF1KB3 GNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
:. ::::.:::.:...::::::.::.:.:: .:::::.::::::.
NP_149 GKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
1380 1390 1400 1410
>>XP_016874319 (OMIM: 108300,120140,132450,150600,151210 (1465 aa)
initn: 9564 init1: 6185 opt: 6965 Z-score: 2427.2 bits: 461.8 E(85289): 1.8e-128
Smith-Waterman score: 6965; 66.7% identity (80.1% similar) in 1395 aa overlap (110-1499:79-1465)
80 90 100 110 120 130
pF1KB3 LDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGS
: :::::::: . ..: .: ::: :: :
XP_016 EEGSLAKTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGE
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB3 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG-L
:::::.:: ::. : ::.: :::::.::.:: ::::: : ::: ::. :.::::: .
XP_016 QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG-P--PGPPGLGGNFAAQMAGGF
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB3 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG
:::.: :.:.:.: : .::.::::: : : : : : :::::.:: ::.: ::: :
XP_016 DEKAG-GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB3 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG
::::::.::: :. :. :: : : :::::::.:::::.:::::. ::.: :::.::::
XP_016 PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB3 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG
:::.: : :. ::.::::.:::::: :: :: : :: :.:: :: ::.: :. :
XP_016 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB3 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPG
::: :: :::::::::::::: :: ::: : :: : : : :::: ::::: .:.::
XP_016 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG
350 360 370 380 390 400
440 450 460 470 480 490
pF1KB3 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG
.: :: :: : :::::.::: : .:: :.::. ::::: :::::::: : :: :: :
XP_016 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG
410 420 430 440 450 460
500 510 520 530 540 550
pF1KB3 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQG
:::::: ::.:: ::: :: :::::::::::::.::: ::::: ::::: : .::::..:
XP_016 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG
470 480 490 500 510 520
560 570 580 590 600 610
pF1KB3 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPG
:::::::::::::::::: :: ::.::.:: ::::::::::::: : ::::: ::.::
XP_016 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG
530 540 550 560 570 580
620 630 640 650 660 670
pF1KB3 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG
:::..:.::: :: : :.:: :: ::::::.: .:: :: : :::::::: :::.::::
XP_016 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG
590 600 610 620 630 640
680 690 700 710 720 730
pF1KB3 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG
:::::::::::::::::::::. :: : .::::::: ::::: :: :: : .:. : :
XP_016 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG
650 660 670 680 690 700
740 750 760 770 780 790
pF1KB3 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG
:::::. ::.: :: ::::::::::::: :: ::::::: .:::: ::. :.::.::
XP_016 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG
710 720 730 740 750 760
800 810 820 830 840 850
pF1KB3 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPG
: ::.::::::: .::::: :: : .: :.:: :: :::.:: : .::::: : :::::
XP_016 LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG
770 780 790 800 810 820
860 870 880 890 900 910
pF1KB3 VKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG
.::: :: :::::::.::::: .:.:::.::.:: : ::.::.:::::::::::.:::::
XP_016 AKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG
830 840 850 860 870 880
920 930 940 950 960 970
pF1KB3 PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG
::: : ::: :: : ::.:: : ::: : ::.:. : :: : ::.::.::.:: :
XP_016 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG
890 900 910 920 930 940
980 990 1000 1010 1020 1030
pF1KB3 PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG
.::::: : .:::::::.::::::::.::::::.: ::: : ::.::.::::::::::
XP_016 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG
950 960 970 980 990 1000
1040 1050 1060 1070 1080 1090
pF1KB3 SNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG
.::.:::: :: : :: ::::::.: .::::. : .: ::. : ::.:::.: : :
XP_016 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG
1010 1020 1030 1040 1050 1060
1100 1110 1120 1130 1140 1150
pF1KB3 QRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPG
.::. :..::.:: : :: ::. ::::::::::. :. :.:: :::::::::::::::::
XP_016 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG
1070 1080 1090 1100 1110 1120
1160 1170 1180 1190 1200 1210
pF1KB3 PNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPG
:.:.::..: :: ::::::::::::::.: : ::::::: :: ::.:: ::::.::
XP_016 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG
1130 1140 1150 1160 1170 1180
1220 1230 1240 1250 1260 1270
pF1KB3 PPGPPGPPG---HLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSL
::::::::: ..: : .: ... :::: . :::: . . : : ::::::
XP_016 PPGPPGPPGPGIDMSAFAG--LGPREKG-PDPLQYMRADQAAGGLR-QHDAEVDATLKSL
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310 1320 1330
pF1KB3 SSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGET
..:::..:::.::.:.::::: :::::: .::.:::::::: . ::.::.::::::::
XP_016 NNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGET
1250 1260 1270 1280 1290 1300
1340 1350 1360 1370 1380 1390
pF1KB3 CISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQ-SPNTAITQMTFLRLLS
:. ::..::.:.::.::: ..: .:.: .: : .:.::: . .:::: .:::::::::
XP_016 CVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLS
1310 1320 1330 1340 1350 1360
1400 1410 1420 1430 1440 1450
pF1KB3 KEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRN
:.:::::: ::::..:.:. : :::::....:.::..:.:::: :: : .:.: :.:..
XP_016 TEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHT
1370 1380 1390 1400 1410 1420
1460 1470 1480 1490
pF1KB3 GNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
:. ::::.:::.:...::::::.::.:.:: .:::::.::::::.
XP_016 GKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
1430 1440 1450 1460
>>XP_016874320 (OMIM: 108300,120140,132450,150600,151210 (1305 aa)
initn: 8971 init1: 5916 opt: 6581 Z-score: 2295.3 bits: 437.2 E(85289): 4.1e-121
Smith-Waterman score: 6581; 66.9% identity (80.4% similar) in 1307 aa overlap (197-1499:4-1305)
170 180 190 200 210 220
pF1KB3 PGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGL
:.:::.: :.:.:.: : .::.::::: :
XP_016 MAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGP
10 20 30
230 240 250 260 270 280
pF1KB3 QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA
: : : : :::::.:: ::.: ::: :::::::.::: :. :. :: : : ::
XP_016 AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR
:::::.:::::.:::::. ::.: :::.:::: :::.: : :. ::.::::.::::::
XP_016 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE
:: :: : :: :.:: :: ::.: :. :::: :: :::::::::::::: :: :::
XP_016 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ
: :: : : : :::: ::::: .:.:: .: :: :: : :::::.::: : .::
XP_016 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB3 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN
:.::. ::::: :::::::: : :: :: ::::::: ::.:: ::: :: ::::::::
XP_016 TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN
280 290 300 310 320 330
530 540 550 560 570 580
pF1KB3 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK
:::::.::: ::::: ::::: : .::::..::::::::::::::::::: :: ::.::
XP_016 RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK
340 350 360 370 380 390
590 600 610 620 630 640
pF1KB3 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK
.:: ::::::::::::: : ::::: ::.:::::..:.::: :: : :.:: :: :::
XP_016 VGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK
400 410 420 430 440 450
650 660 670 680 690 700
pF1KB3 DGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP
:::.: .:: :: : :::::::: :::.:::::::::::::::::::::::::. :: :
XP_016 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL
460 470 480 490 500 510
710 720 730 740 750 760
pF1KB3 LGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGE
.::::::: ::::: :: :: : .:. : : :::::. ::.: :: :::::::::::
XP_016 VGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGE
520 530 540 550 560 570
770 780 790 800 810 820
pF1KB3 RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP
:: :: ::::::: .:::: ::. :.::.::: ::.::::::: .::::: :: : .:
XP_016 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS
580 590 600 610 620 630
830 840 850 860 870 880
pF1KB3 PGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGP
:.:: :: :::.:: : .::::: : :::::.::: :: :::::::.::::: .:.:::
XP_016 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP
640 650 660 670 680 690
890 900 910 920 930 940
pF1KB3 HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGD
.::.:: : ::.::.:::::::::::.:::::::: : ::: :: : ::.:: : :::
XP_016 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD
700 710 720 730 740 750
950 960 970 980 990 1000
pF1KB3 PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM
: ::.:. : :: : ::.::.::.:: : .::::: : .:::::::.::::::::.
XP_016 SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGF
760 770 780 790 800 810
1010 1020 1030 1040 1050 1060
pF1KB3 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE
::::::.: ::: : ::.::.:::::::::: .::.:::: :: : :: ::::::.:
XP_016 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGV
820 830 840 850 860 870
1070 1080 1090 1100 1110 1120
pF1KB3 RGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP
.::::. : .: ::. : ::.:::.: : :.::. :..::.:: : :: ::. :::::
XP_016 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP
880 890 900 910 920 930
1130 1140 1150 1160 1170 1180
pF1KB3 RGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK
:::::. :. :.:: ::::::::::::::::::.:.::..: :: ::::::::::::::
XP_016 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK
940 950 960 970 980 990
1190 1200 1210 1220 1230 1240
pF1KB3 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG---HLTAALGDIMGHYDES
.: : ::::::: :: ::.:: ::::.::::::::::: ..: : .: ...
XP_016 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAG--LGPREKG
1000 1010 1020 1030 1040 1050
1250 1260 1270 1280 1290 1300
pF1KB3 MPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCH
:::: . :::: . . : : ::::::..:::..:::.::.:.::::: ::::::
XP_016 -PDPLQYMRADQAAGGLR-QHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCH
1060 1070 1080 1090 1100
1310 1320 1330 1340 1350 1360
pF1KB3 SAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYG
.::.:::::::: . ::.::.:::::::::. ::..::.:.::.::: ..: .:.:
XP_016 PEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFG
1110 1120 1130 1140 1150 1160
1370 1380 1390 1400 1410 1420
pF1KB3 LDMNRGSQFAYGDHQ-SPNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKA
.: : .:.::: . .:::: .::::::::: :.:::::: ::::..:.:. : :::::
XP_016 ETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKA
1170 1180 1190 1200 1210 1220
1430 1440 1450 1460 1470 1480
pF1KB3 VVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDV
....:.::..:.:::: :: : .:.: :.:..:. ::::.:::.:...::::::.::.:.
XP_016 LLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDI
1230 1240 1250 1260 1270 1280
1490
pF1KB3 GGTDQEFGVEIGPVCFV
:: .:::::.::::::.
XP_016 GGPEQEFGVDIGPVCFL
1290 1300
>>NP_000079 (OMIM: 114000,120150,130000,130060,166200,16 (1464 aa)
initn: 8325 init1: 4975 opt: 6194 Z-score: 2161.3 bits: 412.6 E(85289): 1.2e-113
Smith-Waterman score: 6479; 59.6% identity (72.8% similar) in 1502 aa overlap (11-1499:7-1464)
10 20 30 40 50
pF1KB3 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEI---ACTQNGQMYLNRDIWKPA
: .:..: . . ..::: . :: :.: .:.::: : .::.:::
NP_000 MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPE
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 PCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGE
::.::::::: .::: . :... .: .: ::::::: : :...
NP_000 PCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVC---PDGSES------------
60 70 80 90 100
120 130 140 150 160 170
pF1KB3 PGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG
: : .::.:. ::.: :::: : :. :.::::: :::::
NP_000 -------------PTDQETTGVEGPKGDTGPRG---PRGPAGPPGRDGIPGQPGLPGPPG
110 120 130 140
180 190 200 210 220 230
pF1KB3 HPSHPGPDGLSRPFSAQMA-GLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPT
:. ::: ::. :. :.. : :::: : .: :: .:: :::: : : : :
NP_000 PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISV---PGPMGPSGPRGLPGPPGAPGPQGFQ
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB3 GPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP
:::::::.:: ::.: ::: ::::: :.::: :. : ::: : : ::::.::. :::
NP_000 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB3 GLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQR
:.::::: .::.: ::..: : ::: : : :: : .::::.:::::: : : : :
NP_000 GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGAR
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB3 GAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSP
: : : :: :: : : :::: : :::::: : :: ::::: ::: :::::.:.
NP_000 GNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB3 GLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFK
: : :.:: ::::: .:.:: .: :: : : :::: :: : .:. :.::.:: :
NP_000 GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSK
390 400 410 420 430 440
480 490 500 510 520 530
pF1KB3 GEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLP
:..: :::::: :.::: :: ::::::: ::.:: .: ::: ::::.::.:::::.::.
NP_000 GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA
450 460 470 480 490 500
540 550 560 570 580 590
pF1KB3 GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGED
:::: :::: : .::::: :. ::::: :::::.::::.:: ::.:: :: : :.:
NP_000 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD
510 520 530 540 550 560
600 610 620 630 640 650
pF1KB3 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV
::::::: : ::: : ::.:::::..:.::: :: : : :: : :::::.: .::
NP_000 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP
570 580 590 600 610 620
660 670 680 690 700 710
pF1KB3 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP
:: : ::::::::: : :::::::: :::::.::::.:::::: :: :: : ::::: :
NP_000 GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP
630 640 650 660 670 680
720 730 740 750 760 770
pF1KB3 GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK
:::: : : : .: :. : :: ::. : :.::. : ::::::::::: :: ::::
NP_000 GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK
690 700 710 720 730 740
780 790 800 810 820 830
pF1KB3 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR
:::: : :::.:. :.::.::: ::.::::::: :.::: :: : .:: :.:: ::.:
NP_000 GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR
750 760 770 780 790 800
840 850 860 870 880 890
pF1KB3 GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLK
:: :: : .::::: : :::::.:::::. : ::::: ::: : :: ::: : :.:: :
NP_000 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK
810 820 830 840 850 860
900 910 920 930 940 950
pF1KB3 GGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDR
:.::. ::::::::::.:::::::::.: :: :: : :::: : ::. : :: :.
NP_000 GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KB3 GPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTP
:: :::: :.::.:: :: : : ::: : .::::.::.::::::::.::::::.: :
NP_000 GPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KB3 GKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPA
:: ::.::.:..:::::.:::: :: :: : :: : .:.:::::. : .::::. :::
NP_000 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA
990 1000 1010 1020 1030 1040
1080 1090 1100 1110 1120 1130
pF1KB3 GLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDR
: ::. ::::.::::: : .:.::. : :: :: : .: :: ::::::::::. :..
NP_000 GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ
1050 1060 1070 1080 1090 1100
1140 1150 1160 1170 1180 1190
pF1KB3 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPI
:::: ::::::.:::: ::::: :::: .: :: ::::::: .: ::.: : :::
NP_000 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI
1110 1120 1130 1140 1150 1160
1200 1210 1220 1230 1240 1250
pF1KB3 GPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDES-MPDPLPEFTEDQ
:::: :: .:.::: :::: ::::::::::. . .: : .:.: : ..:
NP_000 GPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS----------AGFDFSFLPQPPQEKAHDG
1170 1180 1190 1200 1210
1260 1270 1280 1290 1300
pF1KB3 AA---PDDKN---KTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSG
. :: : : : .::::::.:::..:::.::.:.::::: :::.::: .::
NP_000 GRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSG
1220 1230 1240 1250 1260 1270
1310 1320 1330 1340 1350 1360
pF1KB3 EYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSP-DNKPVWYGLDMNR
::::::::: :::::.:::::::::. . :: .:.:. ::.: :.. ::.: .:.
NP_000 EYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTD
1280 1290 1300 1310 1320 1330
1370 1380 1390 1400 1410 1420
pF1KB3 GSQFAYGDHQS-PNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKG
: :: :: . : : . :.:::::.: :::::::: :::::.:::.:. :::::..:.:
NP_000 GFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQG
1340 1350 1360 1370 1380 1390
1430 1440 1450 1460 1470 1480
pF1KB3 ANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQ
.:...:.:::: :: : : : :....: ::::.::.: ...::::::.::.:::. ::
NP_000 SNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQ
1400 1410 1420 1430 1440 1450
1490
pF1KB3 EFGVEIGPVCFV
::: ..:::::.
NP_000 EFGFDVGPVCFL
1460
>>NP_000081 (OMIM: 120180,130020,130050) collagen alpha- (1466 aa)
initn: 7609 init1: 4379 opt: 5609 Z-score: 1959.5 bits: 375.2 E(85289): 2.1e-102
Smith-Waterman score: 5859; 54.9% identity (69.7% similar) in 1501 aa overlap (13-1499:11-1466)
10 20 30 40 50 60
pF1KB3 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQ
.:..:: . : ::.: . : :.. :: : .::.::: :::
NP_000 MMSFVQKGSWLLLALLHPTI-ILAQQEAVEGG------CSHLGQSYADRDVWKPEPCQ
10 20 30 40 50
70 80 90 100 110
pF1KB3 ICVCDNGAILCDKIECQDV-LDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPG
:::::.:..::: : :.: ::: .: : :::: :: : :
NP_000 ICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPP-------------------
60 70 80 90
120 130 140 150 160 170
pF1KB3 LVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHP
.:. ::..::: .:::: ::: : : .:.::.:::::.:: :: :
NP_000 -----------TAPTRPPNGQGP---QGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPP
100 110 120 130
180 190 200 210 220 230
pF1KB3 S--HPGPDGLSRPFSAQMAGLDEKSGL--GSQVGLMPGSVGPVGPRGPQGLQGQQGGAG-
. . : : . .: :. . : :::. :. .: .:: .:: :: :: : .:. :. :
NP_000 GICESCPTG-PQNYSPQYDSYDVKSGVAVGGLAG-YPGPAGPPGPPGPPGTSGHPGSPGS
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB3 P--TGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGA
: :::::::. :: :: : : :: : :.::: :: : ::: :. : :: .: :
NP_000 PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGI
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB3 PGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGA
::.::.::::: : .: :::.:::: ::: : : :: ::.:::: :::::: : ::
NP_000 PGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGA
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB3 PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP
: :: : :. : :: : ::..::::.:: :::.::.:. : .: ::::: :: :
NP_000 AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB3 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGV
.:. : :: : .:.::.:: : : : :: : : ::: :..: :.:: :.::
NP_000 AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB3 PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS
: ::: ::.:: : :: : : ::.:: : :.::. : :: .::::::: :: :
NP_000 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB3 DGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGA
.:.:: :: :::: : .::.:. :.::: : :: :: ::. :.:: : .:: :: :.
NP_000 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS
500 510 520 530 540 550
600 610 620 630 640 650
pF1KB3 PGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGP
::.::::::: : ::::: ::.:::::..: ::: :: :. : :: .: :::.::.::
NP_000 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP
560 570 580 590 600 610
660 670 680 690 700 710
pF1KB3 SGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGE
.:: :: : .:..:. ::::: :.::::: :::::.::::. : :: :: : : .:.
NP_000 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD
620 630 640 650 660 670
720 730 740 750 760 770
pF1KB3 RGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGT
: ::::: ::..: :: .: :: ::.: ::. :: : :: .: ::::::::::: :.
NP_000 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS
680 690 700 710 720 730
780 790 800 810 820 830
pF1KB3 PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGN
::::::.: : ::.:. :.:: :: ::.::::::: :.::: : :: : : ::.
NP_000 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS
740 750 760 770 780 790
840 850 860 870 880 890
pF1KB3 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV
:: :::.:: : .:: : : .:.:: ::: : ::.::..: :: : :. :: :: :
NP_000 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP
800 810 820 830 840 850
900 910 920 930 940 950
pF1KB3 PGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGR
:.:: ::. : :::.::::. : :::: : ::: :: : :::.:::: :. :. :
NP_000 QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS
860 870 880 890 900 910
960 970 980 990 1000 1010
pF1KB3 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGP
: :: : : ::.::.:: .: :: :: : :: :: ::..: ::. : :: :: :
NP_000 PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV
920 930 940 950 960 970
1020 1030 1040 1050 1060 1070
pF1KB3 AGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGD
: :: : .: .:..::::: : :: : .:::: .: :.:: :::::. : .::::.
NP_000 KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE
980 990 1000 1010 1020 1030
1080 1090 1100 1110 1120 1130
pF1KB3 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD
: : ::. : :: ::::: : .:.::. : :: : :: ::.:: :::::::::::.
NP_000 NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGE
1040 1050 1060 1070 1080 1090
1140 1150 1160 1170 1180 1190
pF1KB3 HGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGP
:.:: : :::::: : : :: ::: :.::. : ::: ::::: :: :: ::.:. :
NP_000 TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH
1100 1110 1120 1130 1140 1150
1200 1210 1220 1230 1240
pF1KB3 LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD-----IMGHYDESMPDP
::::::: ::. :: : :: ::.:: :::::::: : : : :.
NP_000 PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGF
1160 1170 1180 1190 1200 1210
1250 1260 1270 1280 1290 1300
pF1KB3 LPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQ
: . .. : : .:: . ..:::...:::.. :::::.:.:::.: :::.:: .
NP_000 APYYGDEPM--DFKINTDE-IMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELK
1220 1230 1240 1250 1260 1270
1310 1320 1330 1340 1350 1360
pF1KB3 SGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMN
:::::.::::: :::::.:::::::::::::: .:::: ::...: ..: ::.: .:.
NP_000 SGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMD
1280 1290 1300 1310 1320 1330
1370 1380 1390 1400 1410 1420
pF1KB3 RGSQFAYGDHQSPNTAI-TQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLK
: ::.::. . :. .. .:..::::::..::::::: ::::..:::. . :.:::. :
NP_000 GGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLM
1340 1350 1360 1370 1380 1390
1430 1440 1450 1460 1470 1480
pF1KB3 GANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTD
:.:. ..::::: .: : ::.: :.:..:. .::::::::....::::.:.:: :.:: :
NP_000 GSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPD
1400 1410 1420 1430 1440 1450
1490
pF1KB3 QEFGVEIGPVCFV
:::::..:::::.
NP_000 QEFGVDVGPVCFL
1460
1499 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:48:26 2016 done: Wed Nov 2 22:48:29 2016
Total Scan time: 19.530 Total Display time: 0.920
Function used was FASTA [36.3.4 Apr, 2011]