FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3608, 210 aa
1>>>pF1KB3608 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3953+/-0.000292; mu= 13.3638+/- 0.018
mean_var=66.4232+/-12.922, 0's: 0 Z-trim(117.4): 42 B-trim: 0 in 0/57
Lambda= 0.157367
statistics sampled from 29347 (29389) to 29347 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.345), width: 16
Scan time: 6.450
The best scores are: opt bits E(85289)
NP_148937 (OMIM: 190040,213600,607174,607907,61548 ( 226) 1412 328.8 4.2e-90
NP_002599 (OMIM: 190040,213600,607174,607907,61548 ( 241) 1412 328.8 4.5e-90
NP_148983 (OMIM: 173430) platelet-derived growth f ( 196) 446 109.5 3.9e-24
XP_011513721 (OMIM: 173430) PREDICTED: platelet-de ( 210) 446 109.5 4.2e-24
NP_002598 (OMIM: 173430) platelet-derived growth f ( 211) 446 109.5 4.2e-24
XP_016867778 (OMIM: 173430) PREDICTED: platelet-de ( 224) 446 109.5 4.4e-24
XP_011513720 (OMIM: 173430) PREDICTED: platelet-de ( 234) 446 109.5 4.6e-24
XP_011513718 (OMIM: 173430) PREDICTED: platelet-de ( 249) 446 109.5 4.8e-24
XP_011513719 (OMIM: 173430) PREDICTED: platelet-de ( 241) 408 100.9 1.9e-21
XP_011513717 (OMIM: 173430) PREDICTED: platelet-de ( 256) 408 100.9 2e-21
NP_001230662 (OMIM: 601398) vascular endothelial g ( 188) 188 50.9 1.6e-06
NP_003368 (OMIM: 601398) vascular endothelial grow ( 207) 182 49.5 4.6e-06
NP_004460 (OMIM: 300091) vascular endothelial grow ( 354) 183 49.9 6.1e-06
NP_005420 (OMIM: 601528,615907) vascular endotheli ( 419) 177 48.5 1.8e-05
NP_001280572 (OMIM: 601121) placenta growth factor ( 169) 167 46.1 4.1e-05
NP_002623 (OMIM: 601121) placenta growth factor is ( 170) 167 46.1 4.1e-05
XP_016863944 (OMIM: 608452) PREDICTED: platelet-de ( 310) 166 46.0 8e-05
XP_011530426 (OMIM: 608452) PREDICTED: platelet-de ( 334) 166 46.0 8.5e-05
NP_057289 (OMIM: 608452) platelet-derived growth f ( 345) 166 46.0 8.7e-05
NP_001165095 (OMIM: 192240,603933) vascular endoth ( 215) 160 44.5 0.00015
NP_003367 (OMIM: 192240,603933) vascular endotheli ( 395) 160 44.7 0.00025
NP_001165094 (OMIM: 192240,603933) vascular endoth ( 232) 154 43.2 0.00041
NP_001273973 (OMIM: 192240,603933) vascular endoth ( 163) 152 42.7 0.00042
NP_001165098 (OMIM: 192240,603933) vascular endoth ( 174) 152 42.7 0.00044
NP_001165097 (OMIM: 192240,603933) vascular endoth ( 191) 152 42.7 0.00048
NP_001165100 (OMIM: 192240,603933) vascular endoth ( 191) 152 42.7 0.00048
NP_001191313 (OMIM: 192240,603933) vascular endoth ( 171) 151 42.5 0.00051
NP_001303939 (OMIM: 192240,603933) vascular endoth ( 213) 152 42.7 0.00052
NP_001165096 (OMIM: 192240,603933) vascular endoth ( 209) 151 42.5 0.0006
NP_001020537 (OMIM: 192240,603933) vascular endoth ( 412) 154 43.3 0.00067
NP_001020540 (OMIM: 192240,603933) vascular endoth ( 354) 152 42.8 0.00081
NP_001028928 (OMIM: 192240,603933) vascular endoth ( 371) 152 42.8 0.00084
NP_001020539 (OMIM: 192240,603933) vascular endoth ( 371) 152 42.8 0.00084
NP_001191314 (OMIM: 192240,603933) vascular endoth ( 351) 151 42.6 0.00094
NP_001020538 (OMIM: 192240,603933) vascular endoth ( 389) 151 42.6 0.001
NP_001193941 (OMIM: 601121) placenta growth factor ( 149) 145 41.1 0.0012
NP_001165101 (OMIM: 192240,603933) vascular endoth ( 137) 142 40.4 0.0017
NP_001165099 (OMIM: 192240,603933) vascular endoth ( 147) 142 40.4 0.0018
NP_001165093 (OMIM: 192240,603933) vascular endoth ( 317) 142 40.5 0.0035
NP_001020541 (OMIM: 192240,603933) vascular endoth ( 327) 142 40.5 0.0036
>>NP_148937 (OMIM: 190040,213600,607174,607907,615483) p (226 aa)
initn: 1412 init1: 1412 opt: 1412 Z-score: 1738.5 bits: 328.8 E(85289): 4.2e-90
Smith-Waterman score: 1412; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:17-226)
10 20 30 40
pF1KB3 MLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELES
::::::::::::::::::::::::::::::::::::::::::::
NP_148 MFIMGLGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELES
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 LARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 LARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 NRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 NRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGG
130 140 150 160 170 180
170 180 190 200 210
pF1KB3 SQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
::::::::::::::::::::::::::::::::::::::::::::::
NP_148 SQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
190 200 210 220
>>NP_002599 (OMIM: 190040,213600,607174,607907,615483) p (241 aa)
initn: 1412 init1: 1412 opt: 1412 Z-score: 1738.1 bits: 328.8 E(85289): 4.5e-90
Smith-Waterman score: 1412; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:32-241)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDPGEEDGAELD
::::::::::::::::::::::::::::::
NP_002 NRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 LNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 PPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
190 200 210 220 230 240
>>NP_148983 (OMIM: 173430) platelet-derived growth facto (196 aa)
initn: 468 init1: 395 opt: 446 Z-score: 554.2 bits: 109.5 E(85289): 3.9e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:39-183)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
NP_148 LLGCGYLAHVLAEEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
10 20 30 40 50 60
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
NP_148 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
70 80 90 100 110
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
NP_148 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
NP_148 ATTSLNPDYREEDTDVR
180 190
>>XP_011513721 (OMIM: 173430) PREDICTED: platelet-derive (210 aa)
initn: 484 init1: 395 opt: 446 Z-score: 553.7 bits: 109.5 E(85289): 4.2e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:38-182)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
XP_011 QKLSAPSLPPRPSEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
10 20 30 40 50 60
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
XP_011 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
70 80 90 100 110
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
XP_011 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
XP_011 ATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
180 190 200 210
>>NP_002598 (OMIM: 173430) platelet-derived growth facto (211 aa)
initn: 484 init1: 395 opt: 446 Z-score: 553.7 bits: 109.5 E(85289): 4.2e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:39-183)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
NP_002 LLGCGYLAHVLAEEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
10 20 30 40 50 60
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
NP_002 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
70 80 90 100 110
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
NP_002 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
NP_002 ATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
180 190 200 210
>>XP_016867778 (OMIM: 173430) PREDICTED: platelet-derive (224 aa)
initn: 484 init1: 395 opt: 446 Z-score: 553.3 bits: 109.5 E(85289): 4.4e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:52-196)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
XP_016 LLKNRGGEWGRPEEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
30 40 50 60 70
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
XP_016 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
XP_016 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
XP_016 ATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
200 210 220
>>XP_011513720 (OMIM: 173430) PREDICTED: platelet-derive (234 aa)
initn: 395 init1: 395 opt: 446 Z-score: 553.0 bits: 109.5 E(85289): 4.6e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:77-221)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
XP_011 LLGCGYLAHVLAEEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
50 60 70 80 90 100
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
XP_011 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
110 120 130 140 150
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
XP_011 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
XP_011 ATTSLNPDYREEDTDVR
220 230
>>XP_011513718 (OMIM: 173430) PREDICTED: platelet-derive (249 aa)
initn: 411 init1: 395 opt: 446 Z-score: 552.6 bits: 109.5 E(85289): 4.8e-24
Smith-Waterman score: 446; 48.1% identity (69.5% similar) in 154 aa overlap (5-153:77-221)
10 20 30
pF1KB3 MLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNM
:::: ::::::. : : ::. :: ..
XP_011 LLGCGYLAHVLAEEAEIPREVIERLARSQIHSIR---DLQRLLEIDSVGSEDS--LDTSL
50 60 70 80 90 100
40 50 60 70 80
pF1KB3 TRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
:.:. . . . : : :. : ::. ::::: ..:: : .: :.::::.
XP_011 -RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLI
110 120 130 140 150
90 100 110 120 130 140
pF1KB3 WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : :
XP_011 WPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECAC
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
:..
XP_011 ATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
220 230 240
>>XP_011513719 (OMIM: 173430) PREDICTED: platelet-derive (241 aa)
initn: 424 init1: 395 opt: 408 Z-score: 506.2 bits: 100.9 E(85289): 1.9e-21
Smith-Waterman score: 408; 44.9% identity (70.3% similar) in 138 aa overlap (21-153:94-228)
10 20 30 40
pF1KB3 MLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMT-RSHSGGELESLARGR
::.. .: .:. . :.:. . . . :
XP_011 CSGRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKR
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB3 ----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNN
: :. : ::. ::::: ..:: : .: :.::::.:::::::.::.::::.
XP_011 PLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB3 RNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGS
.:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : : :..
XP_011 SSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDV
190 200 210 220 230 240
170 180 190 200 210
pF1KB3 QEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
XP_011 R
>>XP_011513717 (OMIM: 173430) PREDICTED: platelet-derive (256 aa)
initn: 440 init1: 395 opt: 408 Z-score: 505.8 bits: 100.9 E(85289): 2e-21
Smith-Waterman score: 408; 44.9% identity (70.3% similar) in 138 aa overlap (21-153:94-228)
10 20 30 40
pF1KB3 MLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMT-RSHSGGELESLARGR
::.. .: .:. . :.:. . . . :
XP_011 CSGRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKR
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB3 ----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNN
: :. : ::. ::::: ..:: : .: :.::::.:::::::.::.::::.
XP_011 PLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB3 RNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGS
.:.:.:..:. : :.: :.: ::::: .:.. : ::.:: : : :..
XP_011 SSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGR
190 200 210 220 230 240
170 180 190 200 210
pF1KB3 QEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
XP_011 PRESGKKRKRKRLKPT
250
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:42:56 2016 done: Sat Nov 5 21:42:57 2016
Total Scan time: 6.450 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]