FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3618, 295 aa 1>>>pF1KB3618 295 - 295 aa - 295 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8781+/-0.00086; mu= -3.8126+/- 0.052 mean_var=244.3674+/-48.493, 0's: 0 Z-trim(116.1): 10 B-trim: 0 in 0/54 Lambda= 0.082045 statistics sampled from 16717 (16724) to 16717 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.514), width: 16 Scan time: 3.110 The best scores are: opt bits E(32554) CCDS11585.1 HLF gene_id:3131|Hs108|chr17 ( 295) 2029 252.2 3.5e-67 CCDS82164.1 HLF gene_id:3131|Hs108|chr17 ( 210) 1438 182.1 3e-46 CCDS46716.1 TEF gene_id:7008|Hs108|chr22 ( 273) 1002 130.6 1.3e-30 CCDS14014.1 TEF gene_id:7008|Hs108|chr22 ( 303) 976 127.5 1.2e-29 CCDS12728.1 DBP gene_id:1628|Hs108|chr19 ( 325) 852 112.9 3.3e-25 >>CCDS11585.1 HLF gene_id:3131|Hs108|chr17 (295 aa) initn: 2029 init1: 2029 opt: 2029 Z-score: 1319.7 bits: 252.2 E(32554): 3.5e-67 Smith-Waterman score: 2029; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295) 10 20 30 40 50 60 pF1KB3 MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAK 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 RSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL 250 260 270 280 290 >>CCDS82164.1 HLF gene_id:3131|Hs108|chr17 (210 aa) initn: 1438 init1: 1438 opt: 1438 Z-score: 943.7 bits: 182.1 E(32554): 3e-46 Smith-Waterman score: 1438; 100.0% identity (100.0% similar) in 210 aa overlap (86-295:1-210) 60 70 80 90 100 110 pF1KB3 SPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQP :::::::::::::::::::::::::::::: CCDS82 MDLEEFLSENGIPPSPSQHDHSPHPPGLQP 10 20 30 120 130 140 150 160 170 pF1KB3 ASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGY 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 EPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKN 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 NMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL 160 170 180 190 200 210 >>CCDS46716.1 TEF gene_id:7008|Hs108|chr22 (273 aa) initn: 978 init1: 732 opt: 1002 Z-score: 663.2 bits: 130.6 E(32554): 1.3e-30 Smith-Waterman score: 1002; 56.8% identity (79.1% similar) in 278 aa overlap (21-295:6-273) 10 20 30 40 50 pF1KB3 MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSP-TV ::.::::. : : .. : :.: ::: .::. . :. CCDS46 MDMPEVLKSLLEHSLPWPEKRTD---KEKGKEKLEEDEAAAASTM 10 20 30 40 60 70 80 90 100 110 pF1KB3 PQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPP--GLQPAS :: : : .::::.::::..:.::::::.::: ::::: ::.. :. : :. CCDS46 AVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKE 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 SAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEP ::. :. . : ..: ..:. . .: : .:.:::::::. ..: :...: CCDS46 SASSSTASPPSSSTAIFQPSETVSSTESS-------LEKERETPSPIDPNCVEVDVNFNP 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 DPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNM :::::.:::.:: :.:.:::.::.::.::::::::::.:::.::. ::.:::.::.:::. CCDS46 DPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNV 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 AAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL ::::::::::::::::.:::.::::::.::: :::.::::.::::.:..:::...::: CCDS46 AAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL 220 230 240 250 260 270 >>CCDS14014.1 TEF gene_id:7008|Hs108|chr22 (303 aa) initn: 961 init1: 732 opt: 976 Z-score: 645.9 bits: 127.5 E(32554): 1.2e-29 Smith-Waterman score: 995; 56.5% identity (79.5% similar) in 278 aa overlap (21-295:38-303) 10 20 30 40 50 pF1KB3 MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKL ::..:.::: : .: ..:.: ::: CCDS14 KKPPVDPQAGPGPGPGRAAGERGLSGSFPLVLKKLMENP---P--REARLDKEKGKEKLE 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 DDESNSP-TVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPH .::. . :. :: : : .::::.::::..:.::::::.::: ::::: ::.. :. CCDS14 EDEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 PP--GLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPD : :. ::. :. . : ..: ..:. . .: : .:.:::::::. CCDS14 LPVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESS-------LEKERETPSPIDPN 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 TIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDK ..: :...::::::.:::.:: :.:.:::.::.::.::::::::::.:::.::. ::.: CCDS14 CVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 YWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAK ::.::.:::.::::::::::::::::.:::.::::::.::: :::.::::.::::.:..: CCDS14 YWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSK 240 250 260 270 280 290 290 pF1KB3 YEARHGPL ::...::: CCDS14 YETKYGPL 300 >>CCDS12728.1 DBP gene_id:1628|Hs108|chr19 (325 aa) initn: 847 init1: 673 opt: 852 Z-score: 566.1 bits: 112.9 E(32554): 3.3e-25 Smith-Waterman score: 854; 46.3% identity (67.3% similar) in 324 aa overlap (7-295:10-325) 10 20 30 40 50 pF1KB3 MEKMSRPLPL---NPTFIPPPYGVL---RSLLENPLKLPLHHEDAFSKDKDKEKKLD : :: .:. :: :.: ::::.. : : . . . :.:... : CCDS12 MARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSK-PKEPASCLLKEKERKAALP 10 20 30 40 50 60 70 80 pF1KB3 D--------ESNSPT-------------------VPQSAFLGPTLWDKTLPYDGDTFQLE :. .:. :: ..:.: ::..:::. :: .: CCDS12 AATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPF-GD---VE 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB3 YMDLEEFLSENGIPPSPSQHDH-SPHP-PGLQPASSAAPSVMDLSSRASAPLHPGIPSPN :.::. :: :.:.:::: ::.: :. :: : .:. .: :.: : . CCDS12 YVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAAL 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB3 CMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSE : : : ..:.::::.::::..: . .::::::::::::::.: ::::...::: CCDS12 GTASGHRAGL---TSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSE 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB3 EELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEK :::::::..:::::. .:.. ::.:::.:: ::: ::::::::::::::::..::.:::: CCDS12 EELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEK 240 250 260 270 280 290 270 280 290 pF1KB3 ENSALRQEVADLRKELGKCKNILAKYEARHGPL ::. :::::. .:.::.. . .:..:.:.:: : CCDS12 ENALLRQEVVAVRQELSHYRAVLSRYQAQHGAL 300 310 320 295 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:01:35 2016 done: Fri Nov 4 21:01:35 2016 Total Scan time: 3.110 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]