FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3630, 193 aa 1>>>pF1KB3630 193 - 193 aa - 193 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2539+/-0.000828; mu= 13.7089+/- 0.051 mean_var=76.9560+/-15.259, 0's: 0 Z-trim(109.0): 180 B-trim: 309 in 1/51 Lambda= 0.146202 statistics sampled from 10392 (10598) to 10392 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.326), width: 16 Scan time: 2.010 The best scores are: opt bits E(32554) CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 1305 284.2 3.5e-77 CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 1222 266.7 6.5e-72 CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 1114 243.9 4.7e-65 CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 936 206.3 9.1e-54 CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 726 162.0 2e-40 CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 713 159.3 1.3e-39 CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 702 157.0 6.7e-39 CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 695 155.5 1.9e-38 CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 690 154.4 3.9e-38 CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 684 153.2 9.3e-38 CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 671 150.5 6.7e-37 CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 670 150.3 7.6e-37 CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 658 147.8 5e-36 CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 656 147.3 6.3e-36 CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 644 144.8 3.5e-35 CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 636 143.1 1.1e-34 CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 605 136.6 1.2e-32 CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 546 124.1 6.2e-29 CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 544 123.7 8.4e-29 CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 522 119.0 1.8e-27 CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 378 88.7 2.7e-18 CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 354 84.0 2.3e-16 CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 354 84.0 2.3e-16 CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 354 84.0 2.4e-16 CCDS82774.1 RHOA gene_id:387|Hs108|chr3 ( 90) 342 80.8 2.7e-16 CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 348 82.7 5.4e-16 CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 298 71.8 3.1e-13 CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 297 71.6 3.7e-13 CCDS76691.1 RAB15 gene_id:376267|Hs108|chr14 ( 212) 283 68.6 2.9e-12 CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 280 68.0 4.4e-12 CCDS8264.1 RAB30 gene_id:27314|Hs108|chr11 ( 203) 277 67.4 6.8e-12 CCDS1720.1 RAB10 gene_id:10890|Hs108|chr2 ( 200) 276 67.1 7.7e-12 CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 ( 207) 275 66.9 9.2e-12 CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 274 66.8 1.1e-11 CCDS41846.1 RAB35 gene_id:11021|Hs108|chr12 ( 201) 272 66.3 1.4e-11 CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 271 66.1 1.7e-11 CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 269 65.7 2.2e-11 CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 ( 207) 268 65.5 2.6e-11 CCDS73330.1 RHOD gene_id:29984|Hs108|chr11 ( 144) 266 64.9 2.6e-11 CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 268 65.5 2.6e-11 CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 264 64.6 4.6e-11 CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 263 64.4 5.1e-11 CCDS10460.1 RAB26 gene_id:25837|Hs108|chr16 ( 256) 264 64.7 5.4e-11 CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 263 64.4 5.6e-11 CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 263 64.4 5.7e-11 >>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa) initn: 1305 init1: 1305 opt: 1305 Z-score: 1499.2 bits: 284.2 E(32554): 3.5e-77 Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 130 140 150 160 170 180 190 pF1KB3 VRKNKRRRGCPIL ::::::::::::: CCDS85 VRKNKRRRGCPIL 190 >>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa) initn: 1222 init1: 1222 opt: 1222 Z-score: 1404.6 bits: 266.7 E(32554): 6.5e-72 Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.:: CCDS27 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 130 140 150 160 170 180 190 pF1KB3 VRKNKRRRGCPIL .:..:.. :: .: CCDS27 ARRGKKKSGCLVL 190 >>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa) initn: 1127 init1: 1107 opt: 1114 Z-score: 1281.4 bits: 243.9 E(32554): 4.7e-65 Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-190:1-189) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT :::::::::.::::::::::::::::::.:::::::::::::.::::::::::::::::: CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.:::: CCDS16 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.:: CCDS16 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 130 140 150 160 170 180 190 pF1KB3 VRKNKRRRGCPIL : ... :: CCDS16 KRYGSQN-GCINCCKVL 190 >>CCDS82775.1 RHOA gene_id:387|Hs108|chr3 (187 aa) initn: 936 init1: 936 opt: 936 Z-score: 1078.8 bits: 206.3 E(32554): 9.1e-54 Smith-Waterman score: 936; 98.6% identity (100.0% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: CCDS82 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.::::::::::::::: CCDS82 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP 130 140 150 160 170 180 >>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa) initn: 740 init1: 696 opt: 726 Z-score: 839.2 bits: 162.0 E(32554): 2e-40 Smith-Waterman score: 726; 57.7% identity (76.8% similar) in 194 aa overlap (1-193:1-192) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :: : :.::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.:::: CCDS53 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::.:::.:.:::. :: :.::. :: :::.: :::.::::::.: : CCDS53 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.:. : ..: . : :. .: ::..:.: :::::: :..:.. ::. : :: : CCDS53 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 190 pF1KB3 VRK-NKRRRGCPIL .::.: : .: CCDS53 PPPVKKRKRKCLLL 180 190 >>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa) initn: 719 init1: 700 opt: 713 Z-score: 824.4 bits: 159.3 E(32554): 1.3e-39 Smith-Waterman score: 713; 56.1% identity (77.0% similar) in 187 aa overlap (7-193:5-191) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :.::::: ::::::: .. . ::. :.::::.:: :. :::. :.: :::: CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD ::::.::::: ::::.:.:...:::: :: : ::. .:: ::: : ::.:::.:::.::: CCDS77 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ :: . : :.: .. : :. ..:. .:..: : :::::: ..::.::: :.:: :. CCDS77 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 120 130 140 150 160 170 190 pF1KB3 VRKNKRRRGCPIL :: :.: .: CCDS77 PTPIKRGRSCILL 180 190 >>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa) initn: 715 init1: 672 opt: 702 Z-score: 811.9 bits: 157.0 E(32554): 6.7e-39 Smith-Waterman score: 702; 54.6% identity (77.3% similar) in 194 aa overlap (1-193:1-192) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :: : :.::::: ::::::: .. . :: :.::::.:: :.. ::.: :.:.:::: CCDS13 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::.:::.:.:::. :: : ::. :: :::.: ::..::::::.: : CCDS13 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.:. : ..: . : :. .: .:..:.. :::::: :..:.. ::. : :: : CCDS13 LRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 190 pF1KB3 VRKNKR-RRGCPIL . ... .:.: .: CCDS13 PQPTRQQKRACSLL 180 190 >>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa) initn: 703 init1: 678 opt: 695 Z-score: 803.9 bits: 155.5 E(32554): 1.9e-38 Smith-Waterman score: 695; 54.6% identity (75.0% similar) in 196 aa overlap (1-193:1-192) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :: : :.::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.:::: CCDS11 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::.:::.:.:::. :: :.::. :: :::.: ::..::.:::.: : CCDS11 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLD 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL- ::.:. : ..: : :. .: :: .:.. :::::: :..:.. ::. : :: : CCDS11 LRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 180 190 pF1KB3 --QVRKNKRRRGCPIL :.: .. : .. CCDS11 PPPVKKPGKK--CTVF 180 190 >>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa) initn: 674 init1: 655 opt: 690 Z-score: 798.2 bits: 154.4 E(32554): 3.9e-38 Smith-Waterman score: 690; 52.4% identity (78.6% similar) in 187 aa overlap (7-193:5-191) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :.::::: ::::::: .. ..:: ::::::.:: . . . :. :.:.:: CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::.:::.:.:::. ::.:.::. :::.::. : ::..:..:::.. : CCDS22 AGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQID 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.: : ..::: ::.:. : .. .: ..: :.:::: :..:...::. : :.:. CCDS22 LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 120 130 140 150 160 170 190 pF1KB3 VRKNKRRRGCPIL . :. : : .: CCDS22 PPEPKKSRRCVLL 180 190 >>CCDS222.1 CDC42 gene_id:998|Hs108|chr1 (191 aa) initn: 673 init1: 654 opt: 684 Z-score: 791.4 bits: 153.2 E(32554): 9.3e-38 Smith-Waterman score: 684; 51.9% identity (79.1% similar) in 187 aa overlap (7-193:5-191) 10 20 30 40 50 60 pF1KB3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT : :.::::: ::::::: .. ..:: ::::::.:: . . . :. :.:.:: CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD :::::::::::::::.:::.:.:::. ::.:.::. :::.::. : ::..:..:::.. : CCDS22 AGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQID 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ ::.: : ..::: ::.:. : .. .: ..: :.:::: :..:...::. : :.:. CCDS22 LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALE 120 130 140 150 160 170 190 pF1KB3 VRKNKRRRGCPIL ... .: : :. CCDS22 PPETQPKRKCCIF 180 190 193 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:15:25 2016 done: Sat Nov 5 05:15:25 2016 Total Scan time: 2.010 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]