FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3632, 367 aa 1>>>pF1KB3632 367 - 367 aa - 367 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2405+/-0.000343; mu= 16.9717+/- 0.021 mean_var=69.7720+/-13.844, 0's: 0 Z-trim(114.6): 13 B-trim: 58 in 1/56 Lambda= 0.153544 statistics sampled from 24536 (24548) to 24536 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.288), width: 16 Scan time: 8.480 The best scores are: opt bits E(85289) NP_000365 (OMIM: 176100,613521) uroporphyrinogen d ( 367) 2495 561.7 9.1e-160 XP_005271227 (OMIM: 176100,613521) PREDICTED: urop ( 295) 1850 418.8 7.8e-117 XP_005271226 (OMIM: 176100,613521) PREDICTED: urop ( 295) 1850 418.8 7.8e-117 >>NP_000365 (OMIM: 176100,613521) uroporphyrinogen decar (367 aa) initn: 2495 init1: 2495 opt: 2495 Z-score: 2989.3 bits: 561.7 E(85289): 9.1e-160 Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367) 10 20 30 40 50 60 pF1KB3 MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 AKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 LQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKH 310 320 330 340 350 360 pF1KB3 SRLLRQN ::::::: NP_000 SRLLRQN >>XP_005271227 (OMIM: 176100,613521) PREDICTED: uroporph (295 aa) initn: 1850 init1: 1850 opt: 1850 Z-score: 2218.5 bits: 418.8 E(85289): 7.8e-117 Smith-Waterman score: 1850; 100.0% identity (100.0% similar) in 276 aa overlap (92-367:20-295) 70 80 90 100 110 120 pF1KB3 PEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERL :::::::::::::::::::::::::::::: XP_005 MLPSFSPTSLLYPRCFLPLQALGMEVTMVPGKGPSFPEPLREEQDLERL 10 20 30 40 130 140 150 160 170 180 pF1KB3 RDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWL 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB3 YQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVA 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB3 KQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTL 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB3 QGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHS 230 240 250 260 270 280 pF1KB3 RLLRQN :::::: XP_005 RLLRQN 290 >>XP_005271226 (OMIM: 176100,613521) PREDICTED: uroporph (295 aa) initn: 1850 init1: 1850 opt: 1850 Z-score: 2218.5 bits: 418.8 E(85289): 7.8e-117 Smith-Waterman score: 1850; 100.0% identity (100.0% similar) in 276 aa overlap (92-367:20-295) 70 80 90 100 110 120 pF1KB3 PEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERL :::::::::::::::::::::::::::::: XP_005 MLPSFSPTSLLYPRCFLPLQALGMEVTMVPGKGPSFPEPLREEQDLERL 10 20 30 40 130 140 150 160 170 180 pF1KB3 RDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWL 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB3 YQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVA 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB3 KQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTL 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB3 QGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHS 230 240 250 260 270 280 pF1KB3 RLLRQN :::::: XP_005 RLLRQN 290 367 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:16:04 2016 done: Sat Nov 5 05:16:05 2016 Total Scan time: 8.480 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]