FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3640, 419 aa 1>>>pF1KB3640 419 - 419 aa - 419 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.0327+/-0.000509; mu= -16.3627+/- 0.030 mean_var=652.4742+/-146.849, 0's: 0 Z-trim(118.2): 67 B-trim: 1815 in 1/56 Lambda= 0.050210 statistics sampled from 30938 (31008) to 30938 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.364), width: 16 Scan time: 8.440 The best scores are: opt bits E(85289) NP_787062 (OMIM: 608849) serine/threonine-protein ( 419) 2835 221.0 4.4e-57 NP_653225 (OMIM: 608849) serine/threonine-protein ( 344) 2322 183.7 6.1e-46 NP_001171692 (OMIM: 608849) serine/threonine-prote ( 345) 2210 175.6 1.7e-43 >>NP_787062 (OMIM: 608849) serine/threonine-protein kina (419 aa) initn: 2835 init1: 2835 opt: 2835 Z-score: 1145.7 bits: 221.0 E(85289): 4.4e-57 Smith-Waterman score: 2835; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB3 MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 TTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 SFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 SPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSL 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 LVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL 370 380 390 400 410 >>NP_653225 (OMIM: 608849) serine/threonine-protein kina (344 aa) initn: 2322 init1: 2322 opt: 2322 Z-score: 945.8 bits: 183.7 E(85289): 6.1e-46 Smith-Waterman score: 2322; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341) 10 20 30 40 50 60 pF1KB3 MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 TTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 SFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSL ::::::::::::::::::::::::::::::::::::::::: NP_653 SPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEGLC 310 320 330 340 370 380 390 400 410 pF1KB3 LVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL >>NP_001171692 (OMIM: 608849) serine/threonine-protein k (345 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 902.0 bits: 175.6 E(85289): 1.7e-43 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 330 aa overlap (90-419:16-345) 60 70 80 90 100 110 pF1KB3 GTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVS :::::::::::::::::::::::::::::: NP_001 MFLTRPKVCVDLNRRVTLYGVFTIHFSPNVPSRCLLLELLDVSVS 10 20 30 40 120 130 140 150 160 170 pF1KB3 ELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFG 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB3 LSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGM 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB3 KLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMAL 170 180 190 200 210 220 300 310 320 330 340 350 pF1KB3 CSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVS 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB3 LLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL 290 300 310 320 330 340 419 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:06:53 2016 done: Thu Nov 3 21:06:55 2016 Total Scan time: 8.440 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]