FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3650, 478 aa 1>>>pF1KB3650 478 - 478 aa - 478 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1982+/-0.000795; mu= 15.9799+/- 0.048 mean_var=121.6050+/-23.868, 0's: 0 Z-trim(111.8): 32 B-trim: 50 in 2/50 Lambda= 0.116305 statistics sampled from 12639 (12670) to 12639 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.389), width: 16 Scan time: 3.400 The best scores are: opt bits E(32554) CCDS11229.1 VTN gene_id:7448|Hs108|chr17 ( 478) 3399 581.2 8e-166 CCDS44287.1 PRG4 gene_id:10216|Hs108|chr1 (1311) 446 86.1 2.4e-16 CCDS81411.1 PRG4 gene_id:10216|Hs108|chr1 (1361) 446 86.2 2.5e-16 CCDS44288.1 PRG4 gene_id:10216|Hs108|chr1 (1363) 446 86.2 2.5e-16 CCDS1369.1 PRG4 gene_id:10216|Hs108|chr1 (1404) 446 86.2 2.5e-16 >>CCDS11229.1 VTN gene_id:7448|Hs108|chr17 (478 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 3090.5 bits: 581.2 E(32554): 8e-166 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB3 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL 430 440 450 460 470 >>CCDS44287.1 PRG4 gene_id:10216|Hs108|chr1 (1311 aa) initn: 579 init1: 293 opt: 446 Z-score: 407.0 bits: 86.1 E(32554): 2.4e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:952-1190) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . CCDS44 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 930 940 950 960 970 980 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . CCDS44 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 990 1000 1010 1020 1030 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: CCDS44 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1040 1050 1060 1070 1080 1090 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. CCDS44 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1100 1110 1120 1130 1140 1150 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : CCDS44 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1160 1170 1180 1190 1200 1210 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG CCDS44 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1220 1230 1240 1250 1260 1270 >>CCDS81411.1 PRG4 gene_id:10216|Hs108|chr1 (1361 aa) initn: 730 init1: 293 opt: 446 Z-score: 406.8 bits: 86.2 E(32554): 2.5e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1002-1240) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . CCDS81 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 980 990 1000 1010 1020 1030 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . CCDS81 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1040 1050 1060 1070 1080 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: CCDS81 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1090 1100 1110 1120 1130 1140 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. CCDS81 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1150 1160 1170 1180 1190 1200 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : CCDS81 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1210 1220 1230 1240 1250 1260 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG CCDS81 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1270 1280 1290 1300 1310 1320 >>CCDS44288.1 PRG4 gene_id:10216|Hs108|chr1 (1363 aa) initn: 654 init1: 293 opt: 446 Z-score: 406.7 bits: 86.2 E(32554): 2.5e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1004-1242) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . CCDS44 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 980 990 1000 1010 1020 1030 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . CCDS44 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1040 1050 1060 1070 1080 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: CCDS44 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1090 1100 1110 1120 1130 1140 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. CCDS44 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1150 1160 1170 1180 1190 1200 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : CCDS44 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1210 1220 1230 1240 1250 1260 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG CCDS44 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1270 1280 1290 1300 1310 1320 >>CCDS1369.1 PRG4 gene_id:10216|Hs108|chr1 (1404 aa) initn: 730 init1: 293 opt: 446 Z-score: 406.6 bits: 86.2 E(32554): 2.5e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1045-1283) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . CCDS13 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1020 1030 1040 1050 1060 1070 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . CCDS13 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1080 1090 1100 1110 1120 1130 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: CCDS13 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1140 1150 1160 1170 1180 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. CCDS13 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1190 1200 1210 1220 1230 1240 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : CCDS13 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1250 1260 1270 1280 1290 1300 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG CCDS13 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1310 1320 1330 1340 1350 1360 478 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:17:14 2016 done: Sat Nov 5 05:17:15 2016 Total Scan time: 3.400 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]