FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3650, 478 aa 1>>>pF1KB3650 478 - 478 aa - 478 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4116+/-0.000319; mu= 14.5473+/- 0.020 mean_var=123.7156+/-24.725, 0's: 0 Z-trim(119.0): 59 B-trim: 59 in 1/60 Lambda= 0.115309 statistics sampled from 32426 (32486) to 32426 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.381), width: 16 Scan time: 9.000 The best scores are: opt bits E(85289) NP_000629 (OMIM: 193190) vitronectin precursor [Ho ( 478) 3399 576.5 5.7e-164 XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270) 446 85.6 8.9e-16 NP_001121182 (OMIM: 208250,604283) proteoglycan 4 (1270) 446 85.6 8.9e-16 XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311) 446 85.6 9.1e-16 NP_001121181 (OMIM: 208250,604283) proteoglycan 4 (1311) 446 85.6 9.1e-16 NP_001290161 (OMIM: 208250,604283) proteoglycan 4 (1361) 446 85.6 9.4e-16 NP_001121180 (OMIM: 208250,604283) proteoglycan 4 (1363) 446 85.6 9.4e-16 NP_005798 (OMIM: 208250,604283) proteoglycan 4 iso (1404) 446 85.6 9.6e-16 NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 311 62.9 3e-09 NP_004986 (OMIM: 277950,600754) matrix metalloprot ( 582) 304 61.7 6.5e-09 NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 293 59.9 2.5e-08 XP_011536658 (OMIM: 602285) PREDICTED: matrix meta ( 519) 281 57.8 8.4e-08 XP_011536657 (OMIM: 602285) PREDICTED: matrix meta ( 519) 281 57.8 8.4e-08 XP_011536659 (OMIM: 602285) PREDICTED: matrix meta ( 519) 281 57.8 8.4e-08 NP_057239 (OMIM: 602285) matrix metalloproteinase- ( 603) 281 57.9 9.4e-08 NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471) 227 48.8 4e-05 NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477) 223 48.1 6.3e-05 NP_000604 (OMIM: 142290) hemopexin precursor [Homo ( 462) 222 47.9 7e-05 NP_005931 (OMIM: 185261) stromelysin-3 preproprote ( 488) 210 46.0 0.00029 XP_016873260 (OMIM: 120355) PREDICTED: neutrophil ( 444) 201 44.4 0.00076 NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444) 201 44.4 0.00076 XP_011541137 (OMIM: 120355) PREDICTED: neutrophil ( 444) 201 44.4 0.00076 NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444) 201 44.4 0.00076 NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467) 201 44.5 0.00079 XP_011541136 (OMIM: 120355) PREDICTED: neutrophil ( 476) 201 44.5 0.0008 XP_006719464 (OMIM: 601807,611543) PREDICTED: matr ( 279) 195 43.3 0.0011 NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470) 196 43.6 0.0014 XP_011536661 (OMIM: 601807,611543) PREDICTED: matr ( 426) 195 43.4 0.0015 NP_002420 (OMIM: 601807,611543) matrix metalloprot ( 508) 195 43.5 0.0017 XP_011520907 (OMIM: 608482) PREDICTED: matrix meta ( 352) 189 42.4 0.0026 NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403) 189 42.4 0.0028 NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469) 189 42.5 0.0032 XP_011520906 (OMIM: 608482) PREDICTED: matrix meta ( 478) 189 42.5 0.0032 XP_011520904 (OMIM: 608482) PREDICTED: matrix meta ( 528) 189 42.5 0.0034 NP_071913 (OMIM: 608482) matrix metalloproteinase- ( 562) 189 42.5 0.0036 NP_001165910 (OMIM: 606720) poly(U)-specific endor ( 410) 185 41.7 0.0045 NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476) 182 41.3 0.0072 >>NP_000629 (OMIM: 193190) vitronectin precursor [Homo s (478 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 3064.8 bits: 576.5 E(85289): 5.7e-164 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB3 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL 430 440 450 460 470 >>XP_016855492 (OMIM: 208250,604283) PREDICTED: proteogl (1270 aa) initn: 654 init1: 293 opt: 446 Z-score: 404.2 bits: 85.6 E(85289): 8.9e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:911-1149) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . XP_016 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 890 900 910 920 930 940 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . XP_016 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 950 960 970 980 990 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: XP_016 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1000 1010 1020 1030 1040 1050 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. XP_016 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1060 1070 1080 1090 1100 1110 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : XP_016 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1120 1130 1140 1150 1160 1170 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG XP_016 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1180 1190 1200 1210 1220 1230 >>NP_001121182 (OMIM: 208250,604283) proteoglycan 4 isof (1270 aa) initn: 654 init1: 293 opt: 446 Z-score: 404.2 bits: 85.6 E(85289): 8.9e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:911-1149) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . NP_001 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 890 900 910 920 930 940 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . NP_001 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 950 960 970 980 990 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: NP_001 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1000 1010 1020 1030 1040 1050 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. NP_001 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1060 1070 1080 1090 1100 1110 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : NP_001 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1120 1130 1140 1150 1160 1170 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG NP_001 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1180 1190 1200 1210 1220 1230 >>XP_016855491 (OMIM: 208250,604283) PREDICTED: proteogl (1311 aa) initn: 579 init1: 293 opt: 446 Z-score: 404.0 bits: 85.6 E(85289): 9.1e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:952-1190) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . XP_016 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 930 940 950 960 970 980 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . XP_016 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 990 1000 1010 1020 1030 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: XP_016 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1040 1050 1060 1070 1080 1090 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. XP_016 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1100 1110 1120 1130 1140 1150 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : XP_016 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1160 1170 1180 1190 1200 1210 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG XP_016 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1220 1230 1240 1250 1260 1270 >>NP_001121181 (OMIM: 208250,604283) proteoglycan 4 isof (1311 aa) initn: 579 init1: 293 opt: 446 Z-score: 404.0 bits: 85.6 E(85289): 9.1e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:952-1190) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . NP_001 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 930 940 950 960 970 980 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . NP_001 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 990 1000 1010 1020 1030 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: NP_001 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1040 1050 1060 1070 1080 1090 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. NP_001 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1100 1110 1120 1130 1140 1150 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : NP_001 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1160 1170 1180 1190 1200 1210 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG NP_001 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1220 1230 1240 1250 1260 1270 >>NP_001290161 (OMIM: 208250,604283) proteoglycan 4 isof (1361 aa) initn: 730 init1: 293 opt: 446 Z-score: 403.8 bits: 85.6 E(85289): 9.4e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1002-1240) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . NP_001 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 980 990 1000 1010 1020 1030 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . NP_001 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1040 1050 1060 1070 1080 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: NP_001 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1090 1100 1110 1120 1130 1140 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. NP_001 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1150 1160 1170 1180 1190 1200 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : NP_001 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1210 1220 1230 1240 1250 1260 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG NP_001 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1270 1280 1290 1300 1310 1320 >>NP_001121180 (OMIM: 208250,604283) proteoglycan 4 isof (1363 aa) initn: 654 init1: 293 opt: 446 Z-score: 403.8 bits: 85.6 E(85289): 9.4e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1004-1242) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . NP_001 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 980 990 1000 1010 1020 1030 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . NP_001 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1040 1050 1060 1070 1080 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: NP_001 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1090 1100 1110 1120 1130 1140 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. NP_001 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1150 1160 1170 1180 1190 1200 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : NP_001 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1210 1220 1230 1240 1250 1260 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG NP_001 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1270 1280 1290 1300 1310 1320 >>NP_005798 (OMIM: 208250,604283) proteoglycan 4 isoform (1404 aa) initn: 730 init1: 293 opt: 446 Z-score: 403.7 bits: 85.6 E(85289): 9.6e-16 Smith-Waterman score: 446; 36.4% identity (61.9% similar) in 247 aa overlap (59-295:1045-1283) 30 40 50 60 70 80 pF1KB3 TEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVT---RGDVFTMPEDEYTVYDDGEEKN ::..: : . :::: . : . NP_005 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1020 1030 1040 1050 1060 1070 90 100 110 120 130 140 pF1KB3 NATVHEQVGGPSLTS-DLQAQSKGNPE-QTPVLKPEEEAPAPEVGASKPEGIDSRPETLH ..: .:. . .:. . .... :. : .:: . . .. ::: :. .: :.. . NP_005 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEV---TPD-MDYLPRVPN 1080 1090 1100 1110 1120 1130 150 160 170 180 190 pF1KB3 PG---RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP-KLIRDV : :. : ..:.::: :..: :.::.: ::::.: . :. : : . : .: NP_005 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS--PFSPPSPARRITEV 1140 1150 1160 1170 1180 200 210 220 230 240 250 pF1KB3 WGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALA ::: .:::..::: ::.:::..:: :::::: . . : ::. : :: :. .. :::. NP_005 WGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALS 1190 1200 1210 1220 1230 1240 260 270 280 290 300 310 pF1KB3 LPAHSYSGRERVYFFK-GKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFE :. . : ::::: : . .: ....: :. : : NP_005 T-AKYKNWPESVYFFKRGGSIQQYIYKQEPVQK-CPGRRPALNYPVYGETTQVRRRRFER 1250 1260 1270 1280 1290 1300 320 330 340 350 360 370 pF1KB3 LLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKG NP_005 AIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYD 1310 1320 1330 1340 1350 1360 >>NP_005932 (OMIM: 602262) matrix metalloproteinase-16 p (607 aa) initn: 285 init1: 119 opt: 311 Z-score: 287.1 bits: 62.9 E(85289): 3e-09 Smith-Waterman score: 311; 32.5% identity (61.8% similar) in 191 aa overlap (101-282:282-462) 80 90 100 110 120 pF1KB3 PEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSK--GNPEQTPV-LKPEEEAPAPE- :::. .: : :.. : .: .: . NP_005 LGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRS 260 270 280 290 300 310 130 140 150 160 170 180 pF1KB3 VGASKPEGIDSRPETLHP--GRPQ-PPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYEL . . :. : ::. .: :::. : :. ..:.:. :.... :. .:.:. :. ... NP_005 IPPADPRKND-RPKPPRPPTGRPSYPGAKPNICDGN-FNTLAILRR-EMFVFKDQWFWRV 320 330 340 350 360 190 200 210 220 230 240 pF1KB3 DEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRN .. : ::: : : :. :::.. : .:. .:::..:: :.: .:.: ::.. NP_005 RNNRVMDGYPMQITYFWRGLPPSIDAVYE--NSDGNFVFFKGNKYWVFKDTTLQPGYPHD 370 380 390 400 410 420 250 260 270 280 290 300 pF1KB3 ISDGFDGIPDN-VDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAV . .::: . .:.:. . ..::::: .::.: NP_005 LITLGSGIPPHGIDSAIW-----WEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWK 430 440 450 460 470 480 310 320 330 340 350 360 pF1KB3 FEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAP NP_005 GIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTDRVKE 490 500 510 520 530 540 >>NP_004986 (OMIM: 277950,600754) matrix metalloproteina (582 aa) initn: 263 init1: 105 opt: 304 Z-score: 281.1 bits: 61.7 E(85289): 6.5e-09 Smith-Waterman score: 304; 28.5% identity (58.2% similar) in 239 aa overlap (121-343:286-509) 100 110 120 130 140 150 pF1KB3 EQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPP :. : .:. ::: . : .:. : NP_004 IMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPR-TTSRPSV--PDKPKNP 260 270 280 290 300 310 160 170 180 190 200 pF1KB3 AE-EELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDA . ..:.:. ::. . :. : .:.:. .. ... .. : ::: : . : :. . :.. NP_004 TYGPNICDGN-FDTVAMLR-GEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINT 320 330 340 350 360 370 210 220 230 240 250 260 pF1KB3 AFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIP-DNVDAALA-LPAHSYS :. : . :: .:::...: :... :.: ::..:.. :.: :..:::: .: . NP_004 AYERKD--GKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMP----N 380 390 400 410 420 270 280 290 300 310 320 pF1KB3 GRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSW---EDIFELLF-- : ..:::.:..: :.:... . : . :.: . : :. ...: .. NP_004 G--KTYFFRGNKY--YRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG 430 440 450 460 470 480 330 340 350 360 370 pF1KB3 ---WGRTSAGTR----QPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHR : .. . :. ::: : : NP_004 NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA 490 500 510 520 530 540 478 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:17:15 2016 done: Sat Nov 5 05:17:16 2016 Total Scan time: 9.000 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]