Result of FASTA (omim) for
pF1KB3651
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3651, 1004 aa
1>>>pF1KB3651 1004 - 1004 aa - 1004 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.4277+/-0.000511; mu= -30.7022+/- 0.032
mean_var=727.7874+/-152.672, 0's: 0 Z-trim(123.5): 102 B-trim: 0 in 0/60
Lambda= 0.047541
statistics sampled from 43368 (43478) to 43368 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.51), width: 16
Scan time: 18.890
The best scores are: opt bits E(85289)
NP_004417 (OMIM: 602978,615414) polyhomeotic-like (1004) 6557 465.8 5.2e-130
XP_005253391 (OMIM: 602978,615414) PREDICTED: poly ( 996) 6477 460.3 2.3e-128
XP_016874444 (OMIM: 602978,615414) PREDICTED: poly (1021) 6112 435.3 8.1e-121
XP_011518905 (OMIM: 602978,615414) PREDICTED: poly (1021) 6112 435.3 8.1e-121
XP_011518901 (OMIM: 602978,615414) PREDICTED: poly (1013) 6052 431.2 1.4e-119
XP_011518902 (OMIM: 602978,615414) PREDICTED: poly ( 971) 5675 405.3 8.2e-112
XP_016874446 (OMIM: 602978,615414) PREDICTED: poly ( 954) 5646 403.3 3.2e-111
XP_016874445 (OMIM: 602978,615414) PREDICTED: poly ( 963) 5621 401.6 1.1e-110
XP_016874447 (OMIM: 602978,615414) PREDICTED: poly ( 946) 5583 399.0 6.4e-110
XP_016856007 (OMIM: 602979) PREDICTED: polyhomeoti ( 859) 617 58.3 2e-07
XP_016856006 (OMIM: 602979) PREDICTED: polyhomeoti ( 859) 617 58.3 2e-07
XP_016856005 (OMIM: 602979) PREDICTED: polyhomeoti ( 859) 617 58.3 2e-07
NP_932157 (OMIM: 602979) polyhomeotic-like protein ( 858) 611 57.9 2.7e-07
XP_016856004 (OMIM: 602979) PREDICTED: polyhomeoti ( 881) 607 57.7 3.3e-07
XP_016856003 (OMIM: 602979) PREDICTED: polyhomeoti ( 881) 607 57.7 3.3e-07
XP_016856002 (OMIM: 602979) PREDICTED: polyhomeoti ( 881) 607 57.7 3.3e-07
NP_001317417 (OMIM: 602979) polyhomeotic-like prot ( 830) 603 57.4 3.8e-07
XP_016856010 (OMIM: 602979) PREDICTED: polyhomeoti ( 830) 603 57.4 3.8e-07
XP_011539178 (OMIM: 602979) PREDICTED: polyhomeoti ( 572) 596 56.8 4e-07
XP_016856008 (OMIM: 602979) PREDICTED: polyhomeoti ( 844) 588 56.3 7.9e-07
XP_011539180 (OMIM: 602979) PREDICTED: polyhomeoti ( 546) 579 55.6 8.6e-07
XP_011539179 (OMIM: 602979) PREDICTED: polyhomeoti ( 561) 579 55.6 8.8e-07
NP_001280163 (OMIM: 607372) mediator of RNA polyme ( 731) 544 53.3 5.7e-06
XP_016884309 (OMIM: 607372) PREDICTED: mediator of ( 667) 531 52.4 9.9e-06
NP_001280164 (OMIM: 607372) mediator of RNA polyme ( 722) 532 52.5 1e-05
NP_001280166 (OMIM: 607372) mediator of RNA polyme ( 722) 532 52.5 1e-05
NP_056973 (OMIM: 607372) mediator of RNA polymeras ( 748) 532 52.5 1e-05
XP_005270627 (OMIM: 602979) PREDICTED: polyhomeoti ( 323) 514 51.0 1.3e-05
NP_004418 (OMIM: 602979) polyhomeotic-like protein ( 323) 514 51.0 1.3e-05
XP_011528517 (OMIM: 607372) PREDICTED: mediator of ( 741) 517 51.4 2.1e-05
XP_016884306 (OMIM: 607372) PREDICTED: mediator of ( 749) 517 51.4 2.1e-05
XP_006724327 (OMIM: 607372) PREDICTED: mediator of ( 707) 516 51.3 2.1e-05
XP_016884308 (OMIM: 607372) PREDICTED: mediator of ( 707) 516 51.3 2.1e-05
XP_016884307 (OMIM: 607372) PREDICTED: mediator of ( 707) 516 51.3 2.1e-05
XP_011528516 (OMIM: 607372) PREDICTED: mediator of ( 762) 517 51.4 2.1e-05
NP_001003891 (OMIM: 607372) mediator of RNA polyme ( 788) 517 51.4 2.2e-05
XP_011528520 (OMIM: 607372) PREDICTED: mediator of ( 411) 479 48.6 8e-05
XP_016884310 (OMIM: 607372) PREDICTED: mediator of ( 520) 469 48.0 0.00016
XP_011528521 (OMIM: 607372) PREDICTED: mediator of ( 406) 462 47.5 0.00018
XP_011528522 (OMIM: 607372) PREDICTED: mediator of ( 406) 462 47.5 0.00018
XP_016884311 (OMIM: 607372) PREDICTED: mediator of ( 406) 462 47.5 0.00018
NP_001280165 (OMIM: 607372) mediator of RNA polyme ( 677) 434 45.7 0.001
XP_006724326 (OMIM: 607372) PREDICTED: mediator of ( 717) 419 44.7 0.0022
XP_016856011 (OMIM: 602979) PREDICTED: polyhomeoti ( 672) 413 44.3 0.0027
>>NP_004417 (OMIM: 602978,615414) polyhomeotic-like prot (1004 aa)
initn: 6557 init1: 6557 opt: 6557 Z-score: 2455.1 bits: 465.8 E(85289): 5.2e-130
Smith-Waterman score: 6557; 99.9% identity (100.0% similar) in 1004 aa overlap (1-1004:1-1004)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 AKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTPAPSVPPPTLAMVSRQMG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_004 AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
910 920 930 940 950 960
970 980 990 1000
pF1KB3 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
::::::::::::::::::::::::::::::::::::::::::::
NP_004 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
970 980 990 1000
>>XP_005253391 (OMIM: 602978,615414) PREDICTED: polyhome (996 aa)
initn: 5586 init1: 5586 opt: 6477 Z-score: 2425.5 bits: 460.3 E(85289): 2.3e-128
Smith-Waterman score: 6477; 99.1% identity (99.2% similar) in 1004 aa overlap (1-1004:1-996)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
:::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_005 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLR--------VNRTLGRNVPLASQLILMPN
130 140 150 160 170
190 200 210 220 230 240
pF1KB3 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 AKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTPAPSVPPPTLAMVSRQMG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_005 AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
900 910 920 930 940 950
970 980 990 1000
pF1KB3 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
960 970 980 990
>>XP_016874444 (OMIM: 602978,615414) PREDICTED: polyhome (1021 aa)
initn: 6090 init1: 6090 opt: 6112 Z-score: 2290.0 bits: 435.3 E(85289): 8.1e-121
Smith-Waterman score: 6513; 98.2% identity (98.3% similar) in 1021 aa overlap (1-1004:1-1021)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100
pF1KB3 QLSNAQLHSLAAVQQ-----------------ATIAASRQASSPNTSTTQQQTTTTQASI
::::::::::::::: ::::::::::::::::::::::::::::
XP_016 QLSNAQLHSLAAVQQVRGQQPAGPRGRGQALQATIAASRQASSPNTSTTQQQTTTTQASI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB3 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB3 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB3 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB3 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTP
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_016 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB3 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB3 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB3 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB3 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB3 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
970 980 990 1000 1010 1020
pF1KB3 T
:
XP_016 T
>>XP_011518905 (OMIM: 602978,615414) PREDICTED: polyhome (1021 aa)
initn: 6090 init1: 6090 opt: 6112 Z-score: 2290.0 bits: 435.3 E(85289): 8.1e-121
Smith-Waterman score: 6513; 98.2% identity (98.3% similar) in 1021 aa overlap (1-1004:1-1021)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100
pF1KB3 QLSNAQLHSLAAVQQ-----------------ATIAASRQASSPNTSTTQQQTTTTQASI
::::::::::::::: ::::::::::::::::::::::::::::
XP_011 QLSNAQLHSLAAVQQVRGQQPAGPRGRGQALQATIAASRQASSPNTSTTQQQTTTTQASI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB3 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB3 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB3 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB3 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTP
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_011 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB3 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB3 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB3 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB3 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB3 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
970 980 990 1000 1010 1020
pF1KB3 T
:
XP_011 T
>>XP_011518901 (OMIM: 602978,615414) PREDICTED: polyhome (1013 aa)
initn: 6053 init1: 5586 opt: 6052 Z-score: 2267.8 bits: 431.2 E(85289): 1.4e-119
Smith-Waterman score: 6433; 97.5% identity (97.6% similar) in 1021 aa overlap (1-1004:1-1013)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100
pF1KB3 QLSNAQLHSLAAVQQ-----------------ATIAASRQASSPNTSTTQQQTTTTQASI
::::::::::::::: ::::::::::::::::::::::::::::
XP_011 QLSNAQLHSLAAVQQVRGQQPAGPRGRGQALQATIAASRQASSPNTSTTQQQTTTTQASI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLR--------VNR
130 140 150 160 170
170 180 190 200 210 220
pF1KB3 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB3 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB3 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB3 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB3 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
420 430 440 450 460 470
470 480 490 500 510 520
pF1KB3 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
480 490 500 510 520 530
530 540 550 560 570 580
pF1KB3 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
540 550 560 570 580 590
590 600 610 620 630 640
pF1KB3 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
600 610 620 630 640 650
650 660 670 680 690 700
pF1KB3 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTP
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_011 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTP
660 670 680 690 700 710
710 720 730 740 750 760
pF1KB3 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
720 730 740 750 760 770
770 780 790 800 810 820
pF1KB3 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
780 790 800 810 820 830
830 840 850 860 870 880
pF1KB3 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
840 850 860 870 880 890
890 900 910 920 930 940
pF1KB3 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KB3 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
960 970 980 990 1000 1010
pF1KB3 T
:
XP_011 T
>>XP_011518902 (OMIM: 602978,615414) PREDICTED: polyhome (971 aa)
initn: 5634 init1: 5634 opt: 5675 Z-score: 2128.4 bits: 405.3 E(85289): 8.2e-112
Smith-Waterman score: 6108; 93.3% identity (93.4% similar) in 1021 aa overlap (1-1004:1-971)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100
pF1KB3 QLSNAQLHSLAAVQQ-----------------ATIAASRQASSPNTSTTQQQTTTTQASI
::::::::::::::: :::::::::::::::::::::::::::
XP_011 QLSNAQLHSLAAVQQVRGQQPAGPRGRGQALQATIAASRQASSPNTSTTQQQTTTTQAS-
70 80 90 100 110
110 120 130 140 150 160
pF1KB3 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
:::::::::::
XP_011 -------------------------------------------------PQLGNLLQVNR
120 130
170 180 190 200 210 220
pF1KB3 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB3 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB3 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB3 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
320 330 340 350 360 370
410 420 430 440 450 460
pF1KB3 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
380 390 400 410 420 430
470 480 490 500 510 520
pF1KB3 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
440 450 460 470 480 490
530 540 550 560 570 580
pF1KB3 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
500 510 520 530 540 550
590 600 610 620 630 640
pF1KB3 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
560 570 580 590 600 610
650 660 670 680 690 700
pF1KB3 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTP
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_011 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTP
620 630 640 650 660 670
710 720 730 740 750 760
pF1KB3 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
680 690 700 710 720 730
770 780 790 800 810 820
pF1KB3 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
740 750 760 770 780 790
830 840 850 860 870 880
pF1KB3 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
800 810 820 830 840 850
890 900 910 920 930 940
pF1KB3 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KB3 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
920 930 940 950 960 970
pF1KB3 T
:
XP_011 T
>>XP_016874446 (OMIM: 602978,615414) PREDICTED: polyhome (954 aa)
initn: 5634 init1: 5634 opt: 5646 Z-score: 2117.7 bits: 403.3 E(85289): 3.2e-111
Smith-Waterman score: 6152; 94.9% identity (95.0% similar) in 1004 aa overlap (1-1004:1-954)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQAS------------------
70 80 90 100
130 140 150 160 170 180
pF1KB3 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
::::::::::::::::::::::::::::
XP_016 --------------------------------PQLGNLLQVNRTLGRNVPLASQLILMPN
110 120 130
190 200 210 220 230 240
pF1KB3 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB3 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB3 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB3 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB3 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB3 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB3 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB3 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB3 AKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTPAPSVPPPTLAMVSRQMG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB3 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
680 690 700 710 720 730
790 800 810 820 830 840
pF1KB3 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
740 750 760 770 780 790
850 860 870 880 890 900
pF1KB3 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
800 810 820 830 840 850
910 920 930 940 950 960
pF1KB3 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
860 870 880 890 900 910
970 980 990 1000
pF1KB3 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
920 930 940 950
>>XP_016874445 (OMIM: 602978,615414) PREDICTED: polyhome (963 aa)
initn: 5580 init1: 5580 opt: 5621 Z-score: 2108.4 bits: 401.6 E(85289): 1.1e-110
Smith-Waterman score: 6038; 92.6% identity (92.7% similar) in 1021 aa overlap (1-1004:1-963)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100
pF1KB3 QLSNAQLHSLAAVQQ-----------------ATIAASRQASSPNTSTTQQQTTTTQASI
::::::::::::::: :::::::::::::::::::::::::::
XP_016 QLSNAQLHSLAAVQQVRGQQPAGPRGRGQALQATIAASRQASSPNTSTTQQQTTTTQAS-
70 80 90 100 110
110 120 130 140 150 160
pF1KB3 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR
:::
XP_016 ---------------------------------------------------------VNR
120
170 180 190 200 210 220
pF1KB3 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB3 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB3 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADG
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB3 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHH
310 320 330 340 350 360
410 420 430 440 450 460
pF1KB3 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ
370 380 390 400 410 420
470 480 490 500 510 520
pF1KB3 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP
430 440 450 460 470 480
530 540 550 560 570 580
pF1KB3 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ
490 500 510 520 530 540
590 600 610 620 630 640
pF1KB3 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA
550 560 570 580 590 600
650 660 670 680 690 700
pF1KB3 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTP
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_016 DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTP
610 620 630 640 650 660
710 720 730 740 750 760
pF1KB3 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEK
670 680 690 700 710 720
770 780 790 800 810 820
pF1KB3 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTC
730 740 750 760 770 780
830 840 850 860 870 880
pF1KB3 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSR
790 800 810 820 830 840
890 900 910 920 930 940
pF1KB3 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVE
850 860 870 880 890 900
950 960 970 980 990 1000
pF1KB3 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKE
910 920 930 940 950 960
pF1KB3 T
:
XP_016 T
>>XP_016874447 (OMIM: 602978,615414) PREDICTED: polyhome (946 aa)
initn: 5580 init1: 5580 opt: 5583 Z-score: 2094.4 bits: 399.0 E(85289): 6.4e-110
Smith-Waterman score: 6082; 94.1% identity (94.2% similar) in 1004 aa overlap (1-1004:1-946)
10 20 30 40 50 60
pF1KB3 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQAS------------------
70 80 90 100
130 140 150 160 170 180
pF1KB3 SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
::::::::::::::::::::
XP_016 ----------------------------------------VNRTLGRNVPLASQLILMPN
110 120
190 200 210 220 230 240
pF1KB3 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB3 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB3 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB3 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB3 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
370 380 390 400 410 420
490 500 510 520 530 540
pF1KB3 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
430 440 450 460 470 480
550 560 570 580 590 600
pF1KB3 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
490 500 510 520 530 540
610 620 630 640 650 660
pF1KB3 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
550 560 570 580 590 600
670 680 690 700 710 720
pF1KB3 AKASPVAESPKVMDEKSSLGEKAESVANVNANAPSSELVALTPAPSVPPPTLAMVSRQMG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG
610 620 630 640 650 660
730 740 750 760 770 780
pF1KB3 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
670 680 690 700 710 720
790 800 810 820 830 840
pF1KB3 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
730 740 750 760 770 780
850 860 870 880 890 900
pF1KB3 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
790 800 810 820 830 840
910 920 930 940 950 960
pF1KB3 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
850 860 870 880 890 900
970 980 990 1000
pF1KB3 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
910 920 930 940
>>XP_016856007 (OMIM: 602979) PREDICTED: polyhomeotic-li (859 aa)
initn: 1336 init1: 380 opt: 617 Z-score: 254.2 bits: 58.3 E(85289): 2e-07
Smith-Waterman score: 1388; 35.4% identity (55.2% similar) in 1047 aa overlap (3-1004:17-859)
10 20 30 40
pF1KB3 METESEQNSNSTNG--SSSSGGSSRPQIAQMSLY----ERQAVQAL
: : ....:..: .::::::.:: :.:.: .::.::..
XP_016 MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVI
10 20 30 40 50 60
50 60 70 80
pF1KB3 Q-ALQRQPN-AAQYFHQ--------FMLQ------QQLSNAQLHSLAAVQQATIAASRQA
: ::.:::. ::::..: .::: :.::.:::.::::::::.....::.
XP_016 QQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB3 SSPNTSTTQQQTTTTQASINLATT-SAAQLISRSQSVSSPSATTLTQ-SVLLGNTTSPPL
:. ..... : . . .:::::.. .::::..:.:::.: .:. ..: .::::::.:: :
XP_016 STSGSNVSAQAPAQS-SSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPAL
130 140 150 160 170
150 160 170 180 190 200
pF1KB3 NQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADA
. :::::::: :. ::. :...::.:: :. .. ::.
XP_016 TASQAQMYLRAQM-------------------LIFTPTATVATVQPELGTG-SPARPPTP
180 190 200 210
210 220 230 240 250 260
pF1KB3 DQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSL
:::::..:.::. : . . :: ..: ::
XP_016 AQVQNLTLRTQQTPAAAASGPTPTQPVLP-----------------------------SL
220 230 240 250
270 280 290 300 310 320
pF1KB3 NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVT
:. . ::: : ::. : .. ...: ::.
XP_016 ALKPTPGGSQ---P-----------------LPT--------PAQSRNTAQASPAGAKPG
260 270 280
330 340 350 360 370 380
pF1KB3 VSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQ
... : : .. . .. . :: . .: :.::. . .. ::. : :.:.:::.:. :
XP_016 IAD-SVMEPHKKGDGNSSVPGSMEGRAG--LSRTVPAVAAHPLIAPA-YAQLQPHQLLPQ
290 300 310 320 330
390 400 410 420 430 440
pF1KB3 QQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQA
.. ::: : ::::: : :::: ::..:
XP_016 PSSKHLQP-QFVIQQQ---------------------------PQPQQQQPPPQQSRPVL
340 350 360 370
450 460 470 480 490 500
pF1KB3 TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPV
. :: .: :. . ::. .:... . :. . ::. : :: : .::.
XP_016 QAEPHPQLASVSPSVALQPSS---EAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPT
380 390 400 410 420
510 520 530 540 550 560
pF1KB3 APIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTV
: :: : . :: : :. ..: : : : :. :: .. .:
XP_016 -PDTGPQNGH------PEGVPHTP-----QRRFQHTSAVILQL-QPASPVP-QQCVPDDW
430 440 450 460 470
570 580 590 600 610 620
pF1KB3 QSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAA
. : : . ..:. :. : :: .: .:: . ::
XP_016 KEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVP--------------TSPNIQPSPA-
480 490 500 510
630 640 650 660 670 680
pF1KB3 FYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEK
: :. . :. :.:. : :. :..
XP_016 ------HETGQGIVHALT----------DLSSPGMT------------------SGNGNS
520 530 540
690 700 710 720 730 740
pF1KB3 AESVANVNANAPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFV
: :.: ..:: : :..::::::::::::::.:::::
XP_016 ASSIA---GTAP-----------------------QNGENKPPQAIVKPQILTHVIEGFV
550 560 570
750 760 770 780 790
pF1KB3 IQEGAEPFPVGCSQLL--KESEKPLQTGLPTGLTENQSGGPLG--VDSPSAELDKK--AN
::::::::::: :.:: . ..: : :: : ... .. : . .:. :
XP_016 IQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAP
580 590 600 610 620 630
800 810 820 830 840 850
pF1KB3 L-LKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEANYA-RVR
: :::: ::. : .:. :::::::.:::::::.:... : .. ...:.:. : . :
XP_016 LKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNR
640 650 660 670 680 690
860 870 880 890 900
pF1KB3 RRGPRRSSSDIAR-AKIQG------------KCHRGQEDSSRGSDNSSYDEALSPTSPGP
::. . : ... .: : . ..:::::: ::::::.: ::: : .
XP_016 RRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASS
700 710 720 730 740 750
910 920 930 940 950 960
pF1KB3 LSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEE
. : .:.::: :. .: :.. :: :.:..:.::.::::: :: ::::::::
XP_016 STSRRRQGQRDLELPDMH--MRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEE
760 770 780 790 800 810
970 980 990 1000
pF1KB3 FRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
::.:::::::::::::.:::::::::::::::: :.:..::..
XP_016 FRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS
820 830 840 850
1004 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:34:34 2016 done: Thu Nov 3 13:34:36 2016
Total Scan time: 18.890 Total Display time: 0.400
Function used was FASTA [36.3.4 Apr, 2011]