FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3655, 561 aa 1>>>pF1KB3655 561 - 561 aa - 561 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8099+/-0.000448; mu= 21.6284+/- 0.028 mean_var=68.1405+/-13.806, 0's: 0 Z-trim(109.3): 49 B-trim: 88 in 1/50 Lambda= 0.155372 statistics sampled from 17436 (17467) to 17436 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.547), E-opt: 0.2 (0.205), width: 16 Scan time: 9.770 The best scores are: opt bits E(85289) NP_000608 (OMIM: 206100,600523) natural resistance ( 561) 3668 831.9 0 NP_001167600 (OMIM: 206100,600523) natural resista ( 561) 3668 831.9 0 NP_001167599 (OMIM: 206100,600523) natural resista ( 561) 3668 831.9 0 NP_001167596 (OMIM: 206100,600523) natural resista ( 590) 3668 831.9 0 NP_001167601 (OMIM: 206100,600523) natural resista ( 557) 3588 814.0 0 XP_016874844 (OMIM: 206100,600523) PREDICTED: natu ( 568) 3563 808.4 0 NP_001167598 (OMIM: 206100,600523) natural resista ( 568) 3563 808.4 0 XP_011536706 (OMIM: 206100,600523) PREDICTED: natu ( 568) 3563 808.4 0 XP_011536707 (OMIM: 206100,600523) PREDICTED: natu ( 568) 3563 808.4 0 NP_001167597 (OMIM: 206100,600523) natural resista ( 568) 3563 808.4 0 XP_005268968 (OMIM: 206100,600523) PREDICTED: natu ( 597) 3563 808.4 0 XP_005268969 (OMIM: 206100,600523) PREDICTED: natu ( 564) 3483 790.4 0 XP_016874845 (OMIM: 206100,600523) PREDICTED: natu ( 489) 3023 687.3 3e-197 NP_000569 (OMIM: 600266,607948,610446) natural res ( 550) 2325 530.9 4.1e-150 XP_005246850 (OMIM: 600266,607948,610446) PREDICTE ( 483) 2140 489.3 1.1e-137 XP_016860255 (OMIM: 600266,607948,610446) PREDICTE ( 483) 2140 489.3 1.1e-137 XP_016860254 (OMIM: 600266,607948,610446) PREDICTE ( 509) 1994 456.6 8.4e-128 XP_006712772 (OMIM: 600266,607948,610446) PREDICTE ( 432) 1804 414.0 4.9e-115 XP_005246851 (OMIM: 600266,607948,610446) PREDICTE ( 432) 1804 414.0 4.9e-115 XP_006712773 (OMIM: 600266,607948,610446) PREDICTE ( 432) 1804 414.0 4.9e-115 XP_006712774 (OMIM: 600266,607948,610446) PREDICTE ( 401) 1702 391.1 3.6e-108 XP_011509986 (OMIM: 600266,607948,610446) PREDICTE ( 441) 1617 372.1 2.1e-102 XP_011509987 (OMIM: 600266,607948,610446) PREDICTE ( 441) 1617 372.1 2.1e-102 XP_016860256 (OMIM: 600266,607948,610446) PREDICTE ( 427) 1252 290.3 8.6e-78 >>NP_000608 (OMIM: 206100,600523) natural resistance-ass (561 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 4442.8 bits: 831.9 E(85289): 0 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::::::::::::::::::::: NP_000 GHTVSISKGLLTEEATRGYVK 550 560 >>NP_001167600 (OMIM: 206100,600523) natural resistance- (561 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 4442.8 bits: 831.9 E(85289): 0 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::::::::::::::::::::: NP_001 GHTVSISKGLLTEEATRGYVK 550 560 >>NP_001167599 (OMIM: 206100,600523) natural resistance- (561 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 4442.8 bits: 831.9 E(85289): 0 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::::::::::::::::::::: NP_001 GHTVSISKGLLTEEATRGYVK 550 560 >>NP_001167596 (OMIM: 206100,600523) natural resistance- (590 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 4442.5 bits: 831.9 E(85289): 0 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:30-590) 10 20 30 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAY ::::::::::::::::::::::::::::::: NP_001 MRKKQLKTEAAPHCELKSYSKNSATQVSTMVLGPEQKMSDDSVSGDHGESASLGNINPAY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 SNPSLSQSPGDSEEYFATYFNEKISIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNPSLSQSPGDSEEYFATYFNEKISIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB3 SDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWL 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 MVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFF 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB3 GFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB3 HSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVV 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB3 EVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB3 YSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLP 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB3 FALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHVALYVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHVALYVVA 490 500 510 520 530 540 520 530 540 550 560 pF1KB3 AVVSVAYLGFVFYLGWQCLIALGMSFLDCGHTVSISKGLLTEEATRGYVK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVVSVAYLGFVFYLGWQCLIALGMSFLDCGHTVSISKGLLTEEATRGYVK 550 560 570 580 590 >>NP_001167601 (OMIM: 206100,600523) natural resistance- (557 aa) initn: 3588 init1: 3588 opt: 3588 Z-score: 4345.9 bits: 814.0 E(85289): 0 Smith-Waterman score: 3588; 99.8% identity (100.0% similar) in 550 aa overlap (12-561:8-557) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE .:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTVDYLNSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 480 490 500 510 520 530 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::::::::::::::::::::: NP_001 GHTVSISKGLLTEEATRGYVK 540 550 >>XP_016874844 (OMIM: 206100,600523) PREDICTED: natural (568 aa) initn: 3563 init1: 3563 opt: 3563 Z-score: 4315.5 bits: 808.4 E(85289): 0 Smith-Waterman score: 3563; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::: XP_016 GHTCHLGLTAQPELYLLNTMDADSLVSR 550 560 >>NP_001167598 (OMIM: 206100,600523) natural resistance- (568 aa) initn: 3563 init1: 3563 opt: 3563 Z-score: 4315.5 bits: 808.4 E(85289): 0 Smith-Waterman score: 3563; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::: NP_001 GHTCHLGLTAQPELYLLNTMDADSLVSR 550 560 >>XP_011536706 (OMIM: 206100,600523) PREDICTED: natural (568 aa) initn: 3563 init1: 3563 opt: 3563 Z-score: 4315.5 bits: 808.4 E(85289): 0 Smith-Waterman score: 3563; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::: XP_011 GHTCHLGLTAQPELYLLNTMDADSLVSR 550 560 >>XP_011536707 (OMIM: 206100,600523) PREDICTED: natural (568 aa) initn: 3563 init1: 3563 opt: 3563 Z-score: 4315.5 bits: 808.4 E(85289): 0 Smith-Waterman score: 3563; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::: XP_011 GHTCHLGLTAQPELYLLNTMDADSLVSR 550 560 >>NP_001167597 (OMIM: 206100,600523) natural resistance- (568 aa) initn: 3563 init1: 3563 opt: 3563 Z-score: 4315.5 bits: 808.4 E(85289): 0 Smith-Waterman score: 3563; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB3 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 490 500 510 520 530 540 550 560 pF1KB3 GHTVSISKGLLTEEATRGYVK ::: NP_001 GHTCHLGLTAQPELYLLNTMDADSLVSR 550 560 561 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:17:53 2016 done: Sat Nov 5 05:17:54 2016 Total Scan time: 9.770 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]