FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3657, 360 aa 1>>>pF1KB3657 360 - 360 aa - 360 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.9747+/-0.000768; mu= -44.9760+/- 0.045 mean_var=857.9954+/-186.871, 0's: 0 Z-trim(112.2): 1435 B-trim: 0 in 0/53 Lambda= 0.043786 statistics sampled from 19331 (21057) to 19331 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.247), width: 16 Scan time: 7.450 The best scores are: opt bits E(85289) NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 2419 169.2 1.3e-41 NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 2322 163.0 9.2e-40 XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 2051 146.0 1.4e-34 XP_016865789 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1885 135.4 1.7e-31 NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 1821 131.4 3.1e-30 XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 1812 130.7 3.8e-30 NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 1788 129.2 1.1e-29 XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 1788 129.2 1.1e-29 XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1788 129.3 1.2e-29 XP_016865793 (OMIM: 600289) PREDICTED: mitogen-act ( 258) 1618 118.4 1.7e-26 NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 1618 118.5 2e-26 NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 1597 117.3 5.7e-26 XP_016865791 (OMIM: 600289) PREDICTED: mitogen-act ( 273) 1541 113.6 5.3e-25 XP_016865792 (OMIM: 600289) PREDICTED: mitogen-act ( 270) 1536 113.3 6.5e-25 NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 1487 110.3 7e-24 XP_011529008 (OMIM: 602898) PREDICTED: mitogen-act ( 256) 1265 96.1 9e-20 NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 1081 84.7 3.6e-16 NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 1081 84.7 3.6e-16 NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 1071 84.0 5.9e-16 NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 1012 80.3 7.4e-15 NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1019 81.0 1e-14 NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1019 81.0 1e-14 NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1019 81.0 1e-14 NP_001290181 (OMIM: 602399) mitogen-activated prot ( 357) 958 76.9 7.9e-14 XP_016865131 (OMIM: 602896) PREDICTED: mitogen-act ( 378) 938 75.6 2e-13 XP_016865130 (OMIM: 602896) PREDICTED: mitogen-act ( 382) 938 75.6 2e-13 NP_620708 (OMIM: 602896) mitogen-activated protein ( 382) 938 75.6 2e-13 NP_620707 (OMIM: 602896) mitogen-activated protein ( 382) 938 75.6 2e-13 XP_016865127 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 938 75.7 2.2e-13 NP_620709 (OMIM: 602896) mitogen-activated protein ( 424) 938 75.7 2.2e-13 NP_002743 (OMIM: 602896) mitogen-activated protein ( 424) 938 75.7 2.2e-13 XP_006714954 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 938 75.7 2.2e-13 NP_620634 (OMIM: 601158) mitogen-activated protein ( 384) 928 75.0 3.1e-13 NP_001310254 (OMIM: 601158) mitogen-activated prot ( 384) 928 75.0 3.1e-13 NP_001310250 (OMIM: 601158) mitogen-activated prot ( 384) 928 75.0 3.1e-13 NP_001310259 (OMIM: 601158) mitogen-activated prot ( 427) 928 75.0 3.4e-13 NP_001310251 (OMIM: 601158) mitogen-activated prot ( 427) 928 75.0 3.4e-13 NP_001265476 (OMIM: 601158) mitogen-activated prot ( 427) 928 75.0 3.4e-13 NP_001310252 (OMIM: 601158) mitogen-activated prot ( 427) 928 75.0 3.4e-13 XP_016863929 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 925 74.8 3.5e-13 XP_006714332 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 925 74.9 3.8e-13 XP_016863916 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 925 74.9 3.8e-13 XP_016863917 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 925 74.9 3.8e-13 NP_001304996 (OMIM: 602897) mitogen-activated prot ( 464) 925 74.9 4.1e-13 XP_005263188 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 925 74.9 4.1e-13 XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 907 73.7 7.8e-13 XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 907 73.7 7.8e-13 XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 907 73.7 7.8e-13 XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 907 73.7 7.8e-13 XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 907 73.7 7.8e-13 >>NP_001306 (OMIM: 600289) mitogen-activated protein kin (360 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 868.0 bits: 169.2 E(85289): 1.3e-41 Smith-Waterman score: 2419; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES 310 320 330 340 350 360 >>NP_620581 (OMIM: 600289) mitogen-activated protein kin (360 aa) initn: 2322 init1: 2322 opt: 2322 Z-score: 834.9 bits: 163.0 E(85289): 9.2e-40 Smith-Waterman score: 2322; 96.1% identity (98.6% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::.::. :.::.: NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: : :.... :. :::::::::::::::::::::::::::::::::::::::::::::: NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES 310 320 330 340 350 360 >>XP_011512612 (OMIM: 600289) PREDICTED: mitogen-activat (401 aa) initn: 2050 init1: 2050 opt: 2051 Z-score: 741.7 bits: 146.0 E(85289): 1.4e-34 Smith-Waterman score: 2056; 90.7% identity (94.8% similar) in 345 aa overlap (25-360:57-401) 10 20 30 40 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSP-VGSGAYGSVC--------AAFDTK :. :: . .: ..:: :::::: XP_011 APLLSVASSGRNFPRGRALLPLRALPVLHLQHPSPCTHAGMRSTVCSTQVRCESAAFDTK 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB3 TGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLV 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB3 THLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB3 ILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPG 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB3 TDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLL ::::.::. :.::.::: : :.... :. ::::::::::::::::::::::::::::::: XP_011 TDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLL 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB3 EKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEV 330 340 350 360 370 380 350 360 pF1KB3 ISFVPPPLDQEEMES ::::::::::::::: XP_011 ISFVPPPLDQEEMES 390 400 >>XP_016865789 (OMIM: 600289) PREDICTED: mitogen-activat (328 aa) initn: 1885 init1: 1885 opt: 1885 Z-score: 686.2 bits: 135.4 E(85289): 1.7e-31 Smith-Waterman score: 1885; 100.0% identity (100.0% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :::::::::::::::::::::::::::::::::::::::: XP_016 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES XP_016 KCQHSRDCPRHEGELGLHISCTQTEMQR 310 320 >>NP_002742 (OMIM: 602898) mitogen-activated protein kin (364 aa) initn: 1821 init1: 1821 opt: 1821 Z-score: 663.8 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 1821; 73.2% identity (91.5% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :: : :::::::::.::::.: :.: :::::::::::.:.:.. .::::::::::: NP_002 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :.:::.:::::::::::.::::::::::::::: :.:.:..::::: ::::::::::::: NP_002 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.::: NP_002 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG ::::::::::::::::::::::::::::::::::::: :..::::.:.:.::..::...: NP_002 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: .. .. :..::.::::: ::. .....: ::::::.::: .:::::::.:..:: NP_002 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES .:::::::.:::::.::: :.:::.: :... ..::: :::.::.:: :: NP_002 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL 310 320 330 340 350 360 NP_002 EIEQ >>XP_006715061 (OMIM: 600289) PREDICTED: mitogen-activat (283 aa) initn: 1812 init1: 1812 opt: 1812 Z-score: 662.2 bits: 130.7 E(85289): 3.8e-30 Smith-Waterman score: 1812; 95.1% identity (98.2% similar) in 283 aa overlap (78-360:1-283) 50 60 70 80 90 100 pF1KB3 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH :::::::::::::::::::::::::::::: XP_006 MKHENVIGLLDVFTPARSLEEFNDVYLVTH 10 20 30 110 120 130 140 150 160 pF1KB3 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB3 DFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB3 HINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEK ::.::. :.::.::: : :.... :. ::::::::::::::::::::::::::::::::: XP_006 HIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEK 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB3 MLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVIS 220 230 240 250 260 270 350 360 pF1KB3 FVPPPLDQEEMES ::::::::::::: XP_006 FVPPPLDQEEMES 280 >>NP_620582 (OMIM: 600289) mitogen-activated protein kin (297 aa) initn: 1788 init1: 1788 opt: 1788 Z-score: 653.7 bits: 129.2 E(85289): 1.1e-29 Smith-Waterman score: 1788; 95.0% identity (98.2% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::.::. :.::.: NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: : :.... :. :::::::::::::::::::::::::: NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES >>XP_016865790 (OMIM: 600289) PREDICTED: mitogen-activat (301 aa) initn: 1788 init1: 1788 opt: 1788 Z-score: 653.6 bits: 129.2 E(85289): 1.1e-29 Smith-Waterman score: 1788; 95.0% identity (98.2% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::.::. :.::.: XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: : :.... :. :::::::::::::::::::::::::: XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES XP_016 K >>XP_016865788 (OMIM: 600289) PREDICTED: mitogen-activat (328 aa) initn: 1788 init1: 1788 opt: 1788 Z-score: 653.1 bits: 129.3 E(85289): 1.2e-29 Smith-Waterman score: 1788; 95.0% identity (98.2% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::.::. :.::.: XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: : :.... :. :::::::::::::::::::::::::: XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES XP_016 KCQHSRDCPRHEGELGLHISCTQTEMQR 310 320 >>XP_016865793 (OMIM: 600289) PREDICTED: mitogen-activat (258 aa) initn: 1618 init1: 1618 opt: 1618 Z-score: 596.5 bits: 118.4 E(85289): 1.7e-26 Smith-Waterman score: 1618; 95.2% identity (98.4% similar) in 252 aa overlap (1-252:1-252) 10 20 30 40 50 60 pF1KB3 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG :::::::::::::::::::::::::::::::::::::::::::::::::.::. :.::.: XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA :: : :.... : XP_016 TPGAELLKKISSESDAKP 250 360 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:35:16 2016 done: Thu Nov 3 13:35:17 2016 Total Scan time: 7.450 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]