FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3666, 738 aa 1>>>pF1KB3666 738 - 738 aa - 738 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0643+/-0.00105; mu= 12.2021+/- 0.063 mean_var=102.5794+/-20.988, 0's: 0 Z-trim(106.4): 28 B-trim: 166 in 1/50 Lambda= 0.126632 statistics sampled from 8939 (8964) to 8939 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.275), width: 16 Scan time: 4.010 The best scores are: opt bits E(32554) CCDS61096.1 DNM1L gene_id:10059|Hs108|chr12 ( 738) 4748 878.4 0 CCDS61098.1 DNM1L gene_id:10059|Hs108|chr12 ( 725) 4139 767.2 0 CCDS61095.1 DNM1L gene_id:10059|Hs108|chr12 ( 749) 3673 682.0 8.8e-196 CCDS81680.1 DNM1L gene_id:10059|Hs108|chr12 ( 712) 3526 655.2 1e-187 CCDS8729.1 DNM1L gene_id:10059|Hs108|chr12 ( 736) 3064 570.8 2.7e-162 CCDS8728.1 DNM1L gene_id:10059|Hs108|chr12 ( 699) 2917 543.9 3.1e-154 CCDS8730.1 DNM1L gene_id:10059|Hs108|chr12 ( 710) 2901 541.0 2.4e-153 CCDS61099.1 DNM1L gene_id:10059|Hs108|chr12 ( 533) 2025 380.9 2.8e-105 CCDS43882.1 DNM1 gene_id:1759|Hs108|chr9 ( 851) 1285 245.8 2.1e-64 CCDS75911.1 DNM1 gene_id:1759|Hs108|chr9 ( 851) 1285 245.8 2.1e-64 CCDS75912.1 DNM1 gene_id:1759|Hs108|chr9 ( 864) 1285 245.8 2.1e-64 CCDS6895.1 DNM1 gene_id:1759|Hs108|chr9 ( 864) 1285 245.8 2.1e-64 CCDS32908.1 DNM2 gene_id:1785|Hs108|chr19 ( 866) 1255 240.3 9.6e-63 CCDS45969.1 DNM2 gene_id:1785|Hs108|chr19 ( 870) 1247 238.8 2.6e-62 CCDS32907.1 DNM2 gene_id:1785|Hs108|chr19 ( 866) 1245 238.5 3.4e-62 CCDS59351.1 DNM2 gene_id:1785|Hs108|chr19 ( 869) 1237 237.0 9.4e-62 CCDS45968.1 DNM2 gene_id:1785|Hs108|chr19 ( 870) 1237 237.0 9.4e-62 CCDS60356.1 DNM3 gene_id:26052|Hs108|chr1 ( 555) 1199 230.0 7.7e-60 CCDS44276.1 DNM3 gene_id:26052|Hs108|chr1 ( 859) 1199 230.1 1.1e-59 CCDS53431.1 DNM3 gene_id:26052|Hs108|chr1 ( 863) 1199 230.1 1.1e-59 CCDS13672.1 MX2 gene_id:4600|Hs108|chr21 ( 715) 504 103.1 1.6e-21 CCDS74796.1 MX1 gene_id:4599|Hs108|chr21 ( 508) 481 98.8 2.2e-20 CCDS13673.1 MX1 gene_id:4599|Hs108|chr21 ( 662) 481 98.9 2.8e-20 >>CCDS61096.1 DNM1L gene_id:10059|Hs108|chr12 (738 aa) initn: 4748 init1: 4748 opt: 4748 Z-score: 4689.9 bits: 878.4 E(32554): 0 Smith-Waterman score: 4748; 100.0% identity (100.0% similar) in 738 aa overlap (1-738:1-738) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 670 680 690 700 710 720 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: CCDS61 ALQGASQIIAEIRETHLW 730 >>CCDS61098.1 DNM1L gene_id:10059|Hs108|chr12 (725 aa) initn: 4640 init1: 4139 opt: 4139 Z-score: 4088.7 bits: 767.2 E(32554): 0 Smith-Waterman score: 4618; 98.2% identity (98.2% similar) in 738 aa overlap (1-738:1-725) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: CCDS61 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 650 660 670 680 690 700 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: CCDS61 ALQGASQIIAEIRETHLW 710 720 >>CCDS61095.1 DNM1L gene_id:10059|Hs108|chr12 (749 aa) initn: 3673 init1: 3673 opt: 3673 Z-score: 3628.4 bits: 682.0 E(32554): 8.8e-196 Smith-Waterman score: 4716; 98.5% identity (98.5% similar) in 749 aa overlap (1-738:1-749) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGK-----------VASGGGGVGDGVQEPTTG ::::::::::::::::::::::::::::::: :::::::::::::::::: CCDS61 VSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTG 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB3 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB3 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA 670 680 690 700 710 720 710 720 730 pF1KB3 QRRKEAADMLKALQGASQIIAEIRETHLW ::::::::::::::::::::::::::::: CCDS61 QRRKEAADMLKALQGASQIIAEIRETHLW 730 740 >>CCDS81680.1 DNM1L gene_id:10059|Hs108|chr12 (712 aa) initn: 3526 init1: 3526 opt: 3526 Z-score: 3483.6 bits: 655.2 E(32554): 1e-187 Smith-Waterman score: 4524; 96.5% identity (96.5% similar) in 738 aa overlap (1-738:1-712) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: ::::::::::::::::::::::::::::: CCDS81 VSRDK--------------------------VASGGGGVGDGVQEPTTGNWRGMLKTSKA 550 560 570 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 640 650 660 670 680 690 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: CCDS81 ALQGASQIIAEIRETHLW 700 710 >>CCDS8729.1 DNM1L gene_id:10059|Hs108|chr12 (736 aa) initn: 3565 init1: 3064 opt: 3064 Z-score: 3027.2 bits: 570.8 E(32554): 2.7e-162 Smith-Waterman score: 4586; 96.8% identity (96.8% similar) in 749 aa overlap (1-738:1-736) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: CCDS87 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGK-----------VASGGGGVGDGVQEPTTG ::::::::::::::::::::::::::::::: :::::::::::::::::: CCDS87 VSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTG 530 540 550 560 570 580 590 600 610 620 630 640 pF1KB3 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI 590 600 610 620 630 640 650 660 670 680 690 700 pF1KB3 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA 650 660 670 680 690 700 710 720 730 pF1KB3 QRRKEAADMLKALQGASQIIAEIRETHLW ::::::::::::::::::::::::::::: CCDS87 QRRKEAADMLKALQGASQIIAEIRETHLW 710 720 730 >>CCDS8728.1 DNM1L gene_id:10059|Hs108|chr12 (699 aa) initn: 3418 init1: 2917 opt: 2917 Z-score: 2882.4 bits: 543.9 E(32554): 3.1e-154 Smith-Waterman score: 4394; 94.7% identity (94.7% similar) in 738 aa overlap (1-738:1-699) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: CCDS87 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: ::::::::::::::::::::::::::::: CCDS87 VSRDK--------------------------VASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 630 640 650 660 670 680 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: CCDS87 ALQGASQIIAEIRETHLW 690 >>CCDS8730.1 DNM1L gene_id:10059|Hs108|chr12 (710 aa) initn: 4464 init1: 2901 opt: 2901 Z-score: 2866.5 bits: 541.0 E(32554): 2.4e-153 Smith-Waterman score: 4413; 95.0% identity (95.5% similar) in 738 aa overlap (1-738:1-710) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: CCDS87 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: : :.. . .::::::::::::::::::::::::::::: CCDS87 VSRDK-------LIQDSRRETK--------NVASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 640 650 660 670 680 690 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: CCDS87 ALQGASQIIAEIRETHLW 700 710 >>CCDS61099.1 DNM1L gene_id:10059|Hs108|chr12 (533 aa) initn: 2025 init1: 2025 opt: 2025 Z-score: 2003.6 bits: 380.9 E(32554): 2.8e-105 Smith-Waterman score: 3068; 97.8% identity (97.8% similar) in 490 aa overlap (260-738:44-533) 230 240 250 260 270 280 pF1KB3 LDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSL :::::::::::::::::::::::::::::: CCDS61 KMTLLHGKTQDTFLKGWKQKNGVNFFTPKIRSQLDINNKKSVTDSIRDEYAFLQKKYPSL 20 30 40 50 60 70 290 300 310 320 330 340 pF1KB3 ANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQL 80 90 100 110 120 130 350 360 370 380 390 400 pF1KB3 ITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAI 140 150 160 170 180 190 410 420 430 440 450 460 pF1KB3 RNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLR 200 210 220 230 240 250 470 480 490 500 510 520 pF1KB3 FPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 FPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQR 260 270 280 290 300 310 530 540 550 560 570 pF1KB3 RNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGK-----------VASGGGG :::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS61 RNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGG 320 330 340 350 360 370 580 590 600 610 620 630 pF1KB3 VGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKL 380 390 400 410 420 430 640 650 660 670 680 690 pF1KB3 SAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 SAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLL 440 450 460 470 480 490 700 710 720 730 pF1KB3 DDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW :::::::::::::::::::::::::::::::::::::::: CCDS61 DDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 500 510 520 530 >>CCDS43882.1 DNM1 gene_id:1759|Hs108|chr9 (851 aa) initn: 1520 init1: 765 opt: 1285 Z-score: 1269.7 bits: 245.8 E(32554): 2.1e-64 Smith-Waterman score: 1638; 39.2% identity (66.7% similar) in 780 aa overlap (1-732:6-745) 10 20 30 40 50 pF1KB3 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRG :: :::..:.:::.:...: . ..::::.::: ::.:::::::..::::.:::: CCDS43 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TGIVTRRPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLY .::::::::.::::... : ...::: :.: . CCDS43 SGIVTRRPLVLQLVNATTE-----------------------------YAEFLHCKGKKF 70 80 90 120 130 140 150 160 170 pF1KB3 TDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKD :::.:.: ::: ::.:..:.:::.:: ::.:...::.:.::::::::::::::::::: : CCDS43 TDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPD 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 IELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMD ::.:::.....:... : .::::. ::.:.:.:.:::...::::.:.::..::::::::: CCDS43 IEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMD 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 AGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANR :::: ::: ....:.. : :::::::: ::..::..: .. : :. . .: ::.: CCDS43 EGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADR 220 230 240 250 260 270 300 310 320 330 340 pF1KB3 NGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGE--PVDD--KSATLLQ :: :: ..::. : .:::: :: :..... . .. .. : . : : :. .::: CCDS43 MGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQ 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB3 LITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTA .. .::... . :::.. :.: :: ::::: :::: : : ... .: : CCDS43 MVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYA 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB3 IRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELL :.: : : .::.:...:: .::.:.:...:: :.::..: :. ...: :..: CCDS43 IKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQ 400 410 420 430 440 470 480 490 500 510 520 pF1KB3 RFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQ ..:.:.. . ..:: .:.: :.:.: :. :::::.::.: :: :. : .: CCDS43 QYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFI---GFANA---QQ 450 460 470 480 490 500 530 540 550 560 570 pF1KB3 RRNRLARELPSA------VSRDKSSKVPSA--LAPASQEPSPAASAEA-------DGKVA : :.. .. :. : : . . . .:.: . .:: . : CCDS43 RSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEK 510 520 530 540 550 560 580 590 600 610 pF1KB3 SGGGGVGD-GVQEPTTG-------------NWRGMLKTSKAEELLAEEKSKPIPIMPAS- . .: . ... : . :.. : . :: : : .. . :: CCDS43 KYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLEL-ACETQEEVDSWKASF 570 580 590 600 610 620 620 630 640 650 660 pF1KB3 ------PQK-GHAVNLLDVPV----PVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDS :.. : . .. .... . .:. :.:. :. ::. :: :...: CCDS43 LRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDL 630 640 650 660 670 680 670 680 690 700 710 720 pF1KB3 VPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQ .::..::...:..:. . :::...::. . . :. :: ..:::: : : .::. : . CCDS43 MPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALS 690 700 710 720 730 740 730 pF1KB3 IIAEIRETHLW ::..: CCDS43 IIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAP 750 760 770 780 790 800 >>CCDS75911.1 DNM1 gene_id:1759|Hs108|chr9 (851 aa) initn: 1319 init1: 765 opt: 1285 Z-score: 1269.7 bits: 245.8 E(32554): 2.1e-64 Smith-Waterman score: 1638; 39.4% identity (66.7% similar) in 780 aa overlap (1-732:6-745) 10 20 30 40 50 pF1KB3 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRG :: :::..:.:::.:...: . ..::::.::: ::.:::::::..::::.:::: CCDS75 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TGIVTRRPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLY .::::::::.::::... : ...::: :.: . CCDS75 SGIVTRRPLVLQLVNATTE-----------------------------YAEFLHCKGKKF 70 80 90 120 130 140 150 160 170 pF1KB3 TDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKD :::.:.: ::: ::.:..:.:::.:: ::.:...::.:.::::::::::::::::::: : CCDS75 TDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPD 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 IELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMD ::.:::.....:... : .::::. ::.:.:.:.:::...::::.:.::..::::::::: CCDS75 IEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMD 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 AGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANR :::: ::: ....:.. : :::::::: ::..::..: .. : :. . .: ::.: CCDS75 EGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADR 220 230 240 250 260 270 300 310 320 330 340 pF1KB3 NGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGE--PVDD--KSATLLQ :: :: ..::. : .:::: :: :..... . .. .. : . : : :. .::: CCDS75 MGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQ 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB3 LITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTA .. .::... . :::.. :.: :: ::::: :::: : : ... .: : CCDS75 MVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYA 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB3 IRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELL :.: : : .::.:...:: ::.:...:.:::..::..: :. :..:: ..: CCDS75 IKNIHGIRTGLFTPDLAFEATVKKQVQKLKEPSIKCVDMVVSELTATIRKCS----EKLQ 400 410 420 430 440 470 480 490 500 510 520 pF1KB3 RFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQ ..:.:.. . ..:: .:.: :.:.: :. :::::.::.: :: :. : .: CCDS75 QYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFI---GFANA---QQ 450 460 470 480 490 500 530 540 550 560 570 pF1KB3 RRNRLARELPSA------VSRDKSSKVPSA--LAPASQEPSPAASAEA-------DGKVA : :.. .. :. : : . . . .:.: . .:: . : CCDS75 RSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEK 510 520 530 540 550 560 580 590 600 610 pF1KB3 SGGGGVGD-GVQEPTTG-------------NWRGMLKTSKAEELLAEEKSKPIPIMPAS- . .: . ... : . :.. : . :: : : .. . :: CCDS75 KYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLEL-ACETQEEVDSWKASF 570 580 590 600 610 620 620 630 640 650 660 pF1KB3 ------PQK-GHAVNLLDVPV----PVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDS :.. : . .. .... . .:. :.:. :. ::. :: :...: CCDS75 LRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDL 630 640 650 660 670 680 670 680 690 700 710 720 pF1KB3 VPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQ .::..::...:..:. . :::...::. . . :. :: ..:::: : : .::. : . CCDS75 MPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALS 690 700 710 720 730 740 730 pF1KB3 IIAEIRETHLW ::..: CCDS75 IIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAP 750 760 770 780 790 800 738 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:07:38 2016 done: Thu Nov 3 21:07:39 2016 Total Scan time: 4.010 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]