FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3666, 738 aa 1>>>pF1KB3666 738 - 738 aa - 738 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6359+/-0.000424; mu= 14.8389+/- 0.027 mean_var=107.8882+/-21.748, 0's: 0 Z-trim(113.4): 89 B-trim: 257 in 1/51 Lambda= 0.123477 statistics sampled from 22695 (22784) to 22695 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.267), width: 16 Scan time: 9.410 The best scores are: opt bits E(85289) NP_001265394 (OMIM: 603850,614388) dynamin-1-like ( 738) 4748 857.2 0 NP_001265392 (OMIM: 603850,614388) dynamin-1-like ( 725) 4139 748.7 2e-215 NP_001265393 (OMIM: 603850,614388) dynamin-1-like ( 749) 3673 665.7 2e-190 NP_001317309 (OMIM: 603850,614388) dynamin-1-like ( 712) 3526 639.5 1.4e-182 XP_011518845 (OMIM: 603850,614388) PREDICTED: dyna ( 723) 3510 636.6 1e-181 XP_016874152 (OMIM: 603850,614388) PREDICTED: dyna ( 506) 3272 594.1 4.5e-169 NP_036192 (OMIM: 603850,614388) dynamin-1-like pro ( 736) 3064 557.2 8.8e-158 NP_005681 (OMIM: 603850,614388) dynamin-1-like pro ( 699) 2917 531.0 6.4e-150 NP_036193 (OMIM: 603850,614388) dynamin-1-like pro ( 710) 2901 528.1 4.7e-149 XP_011518846 (OMIM: 603850,614388) PREDICTED: dyna ( 517) 2197 402.6 2e-111 XP_016874154 (OMIM: 603850,614388) PREDICTED: dyna ( 480) 2050 376.4 1.5e-103 XP_016874153 (OMIM: 603850,614388) PREDICTED: dyna ( 491) 2034 373.6 1.1e-102 NP_001265395 (OMIM: 603850,614388) dynamin-1-like ( 533) 2025 372.0 3.5e-102 XP_016869861 (OMIM: 602377,616346) PREDICTED: dyna ( 551) 1285 240.2 1.7e-62 NP_001275666 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 1285 240.3 2.5e-62 XP_016869860 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 1285 240.3 2.5e-62 XP_005251825 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 1285 240.3 2.5e-62 NP_001275667 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 1285 240.3 2.5e-62 XP_005251826 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 1285 240.3 2.5e-62 NP_001005336 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 1285 240.3 2.5e-62 XP_016869862 (OMIM: 602377,616346) PREDICTED: dyna ( 861) 1285 240.3 2.5e-62 NP_001275668 (OMIM: 602377,616346) dynamin-1 isofo ( 864) 1285 240.3 2.5e-62 XP_011516637 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 1285 240.3 2.5e-62 NP_004399 (OMIM: 602377,616346) dynamin-1 isoform ( 864) 1285 240.3 2.5e-62 XP_016869859 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 1285 240.3 2.5e-62 XP_011516638 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 1285 240.3 2.5e-62 XP_016869858 (OMIM: 602377,616346) PREDICTED: dyna ( 867) 1285 240.3 2.5e-62 XP_006717055 (OMIM: 602377,616346) PREDICTED: dyna ( 868) 1285 240.3 2.5e-62 XP_005251820 (OMIM: 602377,616346) PREDICTED: dyna ( 868) 1285 240.3 2.5e-62 XP_006717056 (OMIM: 602377,616346) PREDICTED: dyna ( 498) 1274 238.2 6.2e-62 NP_001005362 (OMIM: 160150,602378,606482,615368) d ( 866) 1255 234.9 1e-60 NP_001005361 (OMIM: 160150,602378,606482,615368) d ( 870) 1247 233.5 2.8e-60 NP_004936 (OMIM: 160150,602378,606482,615368) dyna ( 866) 1245 233.2 3.5e-60 NP_001177645 (OMIM: 160150,602378,606482,615368) d ( 869) 1237 231.7 9.5e-60 NP_001005360 (OMIM: 160150,602378,606482,615368) d ( 870) 1237 231.7 9.5e-60 XP_016856480 (OMIM: 611445) PREDICTED: dynamin-3 i ( 564) 1201 225.2 5.7e-58 XP_016856479 (OMIM: 611445) PREDICTED: dynamin-3 i ( 564) 1201 225.2 5.7e-58 XP_006711331 (OMIM: 611445) PREDICTED: dynamin-3 i ( 565) 1201 225.2 5.7e-58 XP_016856478 (OMIM: 611445) PREDICTED: dynamin-3 i ( 568) 1201 225.2 5.7e-58 XP_016856477 (OMIM: 611445) PREDICTED: dynamin-3 i ( 593) 1201 225.2 5.9e-58 NP_001265181 (OMIM: 611445) dynamin-3 isoform c [H ( 555) 1199 224.9 7.1e-58 XP_016856475 (OMIM: 611445) PREDICTED: dynamin-3 i ( 815) 1201 225.3 7.7e-58 XP_016856471 (OMIM: 611445) PREDICTED: dynamin-3 i ( 858) 1201 225.3 8e-58 XP_016856470 (OMIM: 611445) PREDICTED: dynamin-3 i ( 858) 1201 225.3 8e-58 XP_005245137 (OMIM: 611445) PREDICTED: dynamin-3 i ( 869) 1201 225.3 8.1e-58 XP_005245136 (OMIM: 611445) PREDICTED: dynamin-3 i ( 873) 1201 225.3 8.1e-58 XP_016856469 (OMIM: 611445) PREDICTED: dynamin-3 i ( 878) 1201 225.3 8.1e-58 XP_016856468 (OMIM: 611445) PREDICTED: dynamin-3 i ( 910) 1201 225.3 8.4e-58 XP_016856466 (OMIM: 611445) PREDICTED: dynamin-3 i ( 917) 1201 225.3 8.4e-58 XP_016856465 (OMIM: 611445) PREDICTED: dynamin-3 i ( 921) 1201 225.3 8.5e-58 >>NP_001265394 (OMIM: 603850,614388) dynamin-1-like prot (738 aa) initn: 4748 init1: 4748 opt: 4748 Z-score: 4574.9 bits: 857.2 E(85289): 0 Smith-Waterman score: 4748; 100.0% identity (100.0% similar) in 738 aa overlap (1-738:1-738) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 670 680 690 700 710 720 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: NP_001 ALQGASQIIAEIRETHLW 730 >>NP_001265392 (OMIM: 603850,614388) dynamin-1-like prot (725 aa) initn: 4640 init1: 4139 opt: 4139 Z-score: 3988.7 bits: 748.7 E(85289): 2e-215 Smith-Waterman score: 4618; 98.2% identity (98.2% similar) in 738 aa overlap (1-738:1-725) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 650 660 670 680 690 700 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: NP_001 ALQGASQIIAEIRETHLW 710 720 >>NP_001265393 (OMIM: 603850,614388) dynamin-1-like prot (749 aa) initn: 3673 init1: 3673 opt: 3673 Z-score: 3539.9 bits: 665.7 E(85289): 2e-190 Smith-Waterman score: 4716; 98.5% identity (98.5% similar) in 749 aa overlap (1-738:1-749) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGK-----------VASGGGGVGDGVQEPTTG ::::::::::::::::::::::::::::::: :::::::::::::::::: NP_001 VSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTG 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB3 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB3 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA 670 680 690 700 710 720 710 720 730 pF1KB3 QRRKEAADMLKALQGASQIIAEIRETHLW ::::::::::::::::::::::::::::: NP_001 QRRKEAADMLKALQGASQIIAEIRETHLW 730 740 >>NP_001317309 (OMIM: 603850,614388) dynamin-1-like prot (712 aa) initn: 3526 init1: 3526 opt: 3526 Z-score: 3398.7 bits: 639.5 E(85289): 1.4e-182 Smith-Waterman score: 4524; 96.5% identity (96.5% similar) in 738 aa overlap (1-738:1-712) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: ::::::::::::::::::::::::::::: NP_001 VSRDK--------------------------VASGGGGVGDGVQEPTTGNWRGMLKTSKA 550 560 570 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 640 650 660 670 680 690 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: NP_001 ALQGASQIIAEIRETHLW 700 710 >>XP_011518845 (OMIM: 603850,614388) PREDICTED: dynamin- (723 aa) initn: 4572 init1: 3510 opt: 3510 Z-score: 3383.2 bits: 636.6 E(85289): 1e-181 Smith-Waterman score: 4543; 96.7% identity (97.3% similar) in 738 aa overlap (1-738:1-723) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: : :.. . .::::::::::::::::::::::::::::: XP_011 VSRDK-------LIQDSRRETK--------NVASGGGGVGDGVQEPTTGNWRGMLKTSKA 550 560 570 580 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 650 660 670 680 690 700 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: XP_011 ALQGASQIIAEIRETHLW 710 720 >>XP_016874152 (OMIM: 603850,614388) PREDICTED: dynamin- (506 aa) initn: 3272 init1: 3272 opt: 3272 Z-score: 3156.3 bits: 594.1 E(85289): 4.5e-169 Smith-Waterman score: 3272; 100.0% identity (100.0% similar) in 506 aa overlap (233-738:1-506) 210 220 230 240 250 260 pF1KB3 DMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQ :::::::::::::::::::::::::::::: XP_016 MDAGTDAMDVLMGRVIPVKLGIIGVVNRSQ 10 20 30 270 280 290 300 310 320 pF1KB3 LDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRIN 40 50 60 70 80 90 330 340 350 360 370 380 pF1KB3 VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYI 100 110 120 130 140 150 390 400 410 420 430 440 pF1KB3 FHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSL 160 170 180 190 200 210 450 460 470 480 490 500 pF1KB3 RCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAI 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB3 ELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSP 280 290 300 310 320 330 570 580 590 600 610 620 pF1KB3 AASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKG 340 350 360 370 380 390 630 640 650 660 670 680 pF1KB3 HAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKD 400 410 420 430 440 450 690 700 710 720 730 pF1KB3 TLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 460 470 480 490 500 >>NP_036192 (OMIM: 603850,614388) dynamin-1-like protein (736 aa) initn: 3565 init1: 3064 opt: 3064 Z-score: 2953.7 bits: 557.2 E(85289): 8.8e-158 Smith-Waterman score: 4586; 96.8% identity (96.8% similar) in 749 aa overlap (1-738:1-736) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: NP_036 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGK-----------VASGGGGVGDGVQEPTTG ::::::::::::::::::::::::::::::: :::::::::::::::::: NP_036 VSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTG 530 540 550 560 570 580 590 600 610 620 630 640 pF1KB3 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI 590 600 610 620 630 640 650 660 670 680 690 700 pF1KB3 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA 650 660 670 680 690 700 710 720 730 pF1KB3 QRRKEAADMLKALQGASQIIAEIRETHLW ::::::::::::::::::::::::::::: NP_036 QRRKEAADMLKALQGASQIIAEIRETHLW 710 720 730 >>NP_005681 (OMIM: 603850,614388) dynamin-1-like protein (699 aa) initn: 3418 init1: 2917 opt: 2917 Z-score: 2812.5 bits: 531.0 E(85289): 6.4e-150 Smith-Waterman score: 4394; 94.7% identity (94.7% similar) in 738 aa overlap (1-738:1-699) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: NP_005 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: ::::::::::::::::::::::::::::: NP_005 VSRDK--------------------------VASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 630 640 650 660 670 680 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: NP_005 ALQGASQIIAEIRETHLW 690 >>NP_036193 (OMIM: 603850,614388) dynamin-1-like protein (710 aa) initn: 4464 init1: 2901 opt: 2901 Z-score: 2797.0 bits: 528.1 E(85289): 4.7e-149 Smith-Waterman score: 4413; 95.0% identity (95.5% similar) in 738 aa overlap (1-738:1-710) 10 20 30 40 50 60 pF1KB3 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 RPLILQLVHVSQEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI ::::::::::::::::::::::: :::::::::::::::::::::::: NP_036 RPLILQLVHVSQEDKRKTTGEEN-------------GVEAEEWGKFLHTKNKLYTDFDEI 70 80 90 100 130 140 150 160 170 180 pF1KB3 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB3 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB3 VSRDKSSKVPSALAPASQEPSPAASAEADGKVASGGGGVGDGVQEPTTGNWRGMLKTSKA ::::: : :.. . .::::::::::::::::::::::::::::: NP_036 VSRDK-------LIQDSRRETK--------NVASGGGGVGDGVQEPTTGNWRGMLKTSKA 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIV 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK 640 650 660 670 680 690 730 pF1KB3 ALQGASQIIAEIRETHLW :::::::::::::::::: NP_036 ALQGASQIIAEIRETHLW 700 710 >>XP_011518846 (OMIM: 603850,614388) PREDICTED: dynamin- (517 aa) initn: 2197 init1: 2197 opt: 2197 Z-score: 2121.2 bits: 402.6 E(85289): 2e-111 Smith-Waterman score: 3240; 97.9% identity (97.9% similar) in 517 aa overlap (233-738:1-517) 210 220 230 240 250 260 pF1KB3 DMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQ :::::::::::::::::::::::::::::: XP_011 MDAGTDAMDVLMGRVIPVKLGIIGVVNRSQ 10 20 30 270 280 290 300 310 320 pF1KB3 LDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRIN 40 50 60 70 80 90 330 340 350 360 370 380 pF1KB3 VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYI 100 110 120 130 140 150 390 400 410 420 430 440 pF1KB3 FHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSL 160 170 180 190 200 210 450 460 470 480 490 500 pF1KB3 RCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAI 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB3 ELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSP 280 290 300 310 320 330 570 580 590 600 610 pF1KB3 AASAEADGK-----------VASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKP ::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 AASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKP 340 350 360 370 380 390 620 630 640 650 660 670 pF1KB3 IPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKA 400 410 420 430 440 450 680 690 700 710 720 730 pF1KB3 VMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAE 460 470 480 490 500 510 pF1KB3 IRETHLW ::::::: XP_011 IRETHLW 738 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:07:39 2016 done: Thu Nov 3 21:07:41 2016 Total Scan time: 9.410 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]