FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3671, 376 aa 1>>>pF1KB3671 376 - 376 aa - 376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3361+/-0.000447; mu= 16.8262+/- 0.028 mean_var=71.6765+/-14.425, 0's: 0 Z-trim(109.9): 133 B-trim: 19 in 1/53 Lambda= 0.151491 statistics sampled from 17986 (18126) to 17986 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.213), width: 16 Scan time: 8.360 The best scores are: opt bits E(85289) NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 2458 546.8 3e-155 XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 2458 546.8 3e-155 XP_016866431 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 2104 469.4 5.2e-132 XP_011512980 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 2104 469.4 5.2e-132 XP_016866432 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 2104 469.4 5.2e-132 NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1569 352.5 9.3e-97 NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1569 352.5 9.3e-97 NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 1569 352.5 9.3e-97 NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1569 352.5 9.3e-97 XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1569 352.5 9.3e-97 NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1569 352.5 9.3e-97 XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1569 352.5 9.3e-97 NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 1569 352.5 9.4e-97 XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 1569 352.5 9.4e-97 NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 1569 352.5 9.6e-97 NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 1569 352.5 9.7e-97 XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 1569 352.5 1.1e-96 NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 1561 350.7 3.1e-96 NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 1561 350.7 3.1e-96 XP_011512978 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1354 305.5 1.2e-82 XP_016866430 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1354 305.5 1.2e-82 XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 1246 281.9 1.7e-75 NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 1246 281.9 1.7e-75 XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 1246 281.9 1.7e-75 XP_011512637 (OMIM: 130135) PREDICTED: leukocyte e ( 330) 1052 239.5 8.7e-63 XP_016881280 (OMIM: 601697,617115) PREDICTED: serp ( 247) 1008 229.8 5.4e-60 XP_006722547 (OMIM: 601697,617115) PREDICTED: serp ( 247) 1008 229.8 5.4e-60 NP_001027018 (OMIM: 601697,617115) serpin B8 isofo ( 242) 1006 229.3 7.2e-60 XP_011524327 (OMIM: 601697,617115) PREDICTED: serp ( 259) 1005 229.1 8.8e-60 XP_016881279 (OMIM: 601697,617115) PREDICTED: serp ( 259) 1005 229.1 8.8e-60 NP_005015 (OMIM: 602058) serpin B10 [Homo sapiens] ( 397) 996 227.3 4.9e-59 XP_011524329 (OMIM: 602058) PREDICTED: serpin B10 ( 397) 996 227.3 4.9e-59 NP_001137290 (OMIM: 173390) plasminogen activator ( 415) 996 227.3 5e-59 NP_002566 (OMIM: 173390) plasminogen activator inh ( 415) 996 227.3 5e-59 NP_002965 (OMIM: 600518) serpin B4 isoform 1 [Homo ( 390) 967 220.9 3.9e-57 XP_011524440 (OMIM: 600518) PREDICTED: serpin B4 i ( 390) 967 220.9 3.9e-57 NP_008850 (OMIM: 600517) serpin B3 [Homo sapiens] ( 390) 943 215.7 1.5e-55 XP_011524331 (OMIM: 604445) PREDICTED: serpin B13 ( 390) 922 211.1 3.5e-54 NP_001294852 (OMIM: 604445) serpin B13 isoform 1 [ ( 400) 918 210.2 6.6e-54 NP_036529 (OMIM: 604445) serpin B13 isoform 2 [Hom ( 391) 915 209.6 1e-53 XP_016881556 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 906 207.6 4.3e-53 NP_001294857 (OMIM: 615662) serpin B12 isoform 1 [ ( 425) 906 207.6 4.3e-53 XP_011524551 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 906 207.6 4.3e-53 XP_011524550 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 906 207.6 4.3e-53 XP_011524548 (OMIM: 615662) PREDICTED: serpin B12 ( 432) 906 207.6 4.3e-53 XP_005266835 (OMIM: 615662) PREDICTED: serpin B12 ( 437) 906 207.6 4.4e-53 NP_536722 (OMIM: 615662) serpin B12 isoform 2 [Hom ( 405) 892 204.6 3.4e-52 NP_002630 (OMIM: 154790) serpin B5 [Homo sapiens] ( 375) 890 204.1 4.4e-52 NP_536723 (OMIM: 615682) serpin B11 isoform a [Hom ( 392) 879 201.7 2.4e-51 XP_011524553 (OMIM: 615682) PREDICTED: serpin B11 ( 392) 879 201.7 2.4e-51 >>NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] (376 aa) initn: 2458 init1: 2458 opt: 2458 Z-score: 2908.1 bits: 546.8 E(85289): 3e-155 Smith-Waterman score: 2458; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR 310 320 330 340 350 360 370 pF1KB3 HNRANSILFCGRFSSP :::::::::::::::: NP_004 HNRANSILFCGRFSSP 370 >>XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 isofo (376 aa) initn: 2458 init1: 2458 opt: 2458 Z-score: 2908.1 bits: 546.8 E(85289): 3e-155 Smith-Waterman score: 2458; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR 310 320 330 340 350 360 370 pF1KB3 HNRANSILFCGRFSSP :::::::::::::::: XP_005 HNRANSILFCGRFSSP 370 >>XP_016866431 (OMIM: 601799) PREDICTED: serpin B9 isofo (325 aa) initn: 2104 init1: 2104 opt: 2104 Z-score: 2490.9 bits: 469.4 E(85289): 5.2e-132 Smith-Waterman score: 2104; 100.0% identity (100.0% similar) in 320 aa overlap (57-376:6-325) 30 40 50 60 70 80 pF1KB3 NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQYLL :::::::::::::::::::::::::::::: XP_016 MSPCLALSLNTEEDIHRAFQSLLTEVNKAGTQYLL 10 20 30 90 100 110 120 130 140 pF1KB3 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG 220 230 240 250 260 270 330 340 350 360 370 pF1KB3 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 280 290 300 310 320 >>XP_011512980 (OMIM: 601799) PREDICTED: serpin B9 isofo (325 aa) initn: 2104 init1: 2104 opt: 2104 Z-score: 2490.9 bits: 469.4 E(85289): 5.2e-132 Smith-Waterman score: 2104; 100.0% identity (100.0% similar) in 320 aa overlap (57-376:6-325) 30 40 50 60 70 80 pF1KB3 NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQYLL :::::::::::::::::::::::::::::: XP_011 MSPCLALSLNTEEDIHRAFQSLLTEVNKAGTQYLL 10 20 30 90 100 110 120 130 140 pF1KB3 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG 220 230 240 250 260 270 330 340 350 360 370 pF1KB3 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 280 290 300 310 320 >>XP_016866432 (OMIM: 601799) PREDICTED: serpin B9 isofo (325 aa) initn: 2104 init1: 2104 opt: 2104 Z-score: 2490.9 bits: 469.4 E(85289): 5.2e-132 Smith-Waterman score: 2104; 100.0% identity (100.0% similar) in 320 aa overlap (57-376:6-325) 30 40 50 60 70 80 pF1KB3 NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQYLL :::::::::::::::::::::::::::::: XP_016 MSPCLALSLNTEEDIHRAFQSLLTEVNKAGTQYLL 10 20 30 90 100 110 120 130 140 pF1KB3 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEG 220 230 240 250 260 270 330 340 350 360 370 pF1KB3 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 280 290 300 310 320 >>NP_001284629 (OMIM: 173321,613453) serpin B6 isoform a (376 aa) initn: 1435 init1: 1033 opt: 1569 Z-score: 1858.1 bits: 352.5 E(85289): 9.3e-97 Smith-Waterman score: 1569; 62.8% identity (86.3% similar) in 379 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :..:..:.::::. ::: : .:: :.::: ::.:.: ::::: .:::::::.:::: ::. NP_001 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 10 20 30 40 50 70 80 90 100 110 pF1KB3 NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK : :::..::::::::::.::::::: ::::::::.:.:::.:..:: .::.::.. NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE ::.:: :.:.:::::::::..:::::: ::: .:.: ::::::::.::.:.:.: ::. NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV :.: ::....:..:::::....::: ...::. .:.: :::. :::.....:::. . NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK .: :::: ::.::.. ::. : : :::: ::.:::.:.::::::::.::..:::. :: NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF ::.:.:: . :: ::: ::::::::::::::::::.. ... .: . ::::::::::: NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 300 310 320 330 340 350 360 370 pF1KB3 FIRHNRANSILFCGRFSSP ::.:...:.:::::::::: NP_001 FIQHSKTNGILFCGRFSSP 360 370 >>NP_001258754 (OMIM: 173321,613453) serpin B6 isoform a (376 aa) initn: 1435 init1: 1033 opt: 1569 Z-score: 1858.1 bits: 352.5 E(85289): 9.3e-97 Smith-Waterman score: 1569; 62.8% identity (86.3% similar) in 379 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :..:..:.::::. ::: : .:: :.::: ::.:.: ::::: .:::::::.:::: ::. NP_001 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 10 20 30 40 50 70 80 90 100 110 pF1KB3 NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK : :::..::::::::::.::::::: ::::::::.:.:::.:..:: .::.::.. NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE ::.:: :.:.:::::::::..:::::: ::: .:.: ::::::::.::.:.:.: ::. NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV :.: ::....:..:::::....::: ...::. .:.: :::. :::.....:::. . NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK .: :::: ::.::.. ::. : : :::: ::.:::.:.::::::::.::..:::. :: NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF ::.:.:: . :: ::: ::::::::::::::::::.. ... .: . ::::::::::: NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 300 310 320 330 340 350 360 370 pF1KB3 FIRHNRANSILFCGRFSSP ::.:...:.:::::::::: NP_001 FIQHSKTNGILFCGRFSSP 360 370 >>NP_004559 (OMIM: 173321,613453) serpin B6 isoform a [H (376 aa) initn: 1435 init1: 1033 opt: 1569 Z-score: 1858.1 bits: 352.5 E(85289): 9.3e-97 Smith-Waterman score: 1569; 62.8% identity (86.3% similar) in 379 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :..:..:.::::. ::: : .:: :.::: ::.:.: ::::: .:::::::.:::: ::. NP_004 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 10 20 30 40 50 70 80 90 100 110 pF1KB3 NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK : :::..::::::::::.::::::: ::::::::.:.:::.:..:: .::.::.. NP_004 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE ::.:: :.:.:::::::::..:::::: ::: .:.: ::::::::.::.:.:.: ::. NP_004 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV :.: ::....:..:::::....::: ...::. .:.: :::. :::.....:::. . NP_004 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK .: :::: ::.::.. ::. : : :::: ::.:::.:.::::::::.::..:::. :: NP_004 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF ::.:.:: . :: ::: ::::::::::::::::::.. ... .: . ::::::::::: NP_004 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 300 310 320 330 340 350 360 370 pF1KB3 FIRHNRANSILFCGRFSSP ::.:...:.:::::::::: NP_004 FIQHSKTNGILFCGRFSSP 360 370 >>NP_001258753 (OMIM: 173321,613453) serpin B6 isoform a (376 aa) initn: 1435 init1: 1033 opt: 1569 Z-score: 1858.1 bits: 352.5 E(85289): 9.3e-97 Smith-Waterman score: 1569; 62.8% identity (86.3% similar) in 379 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :..:..:.::::. ::: : .:: :.::: ::.:.: ::::: .:::::::.:::: ::. NP_001 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 10 20 30 40 50 70 80 90 100 110 pF1KB3 NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK : :::..::::::::::.::::::: ::::::::.:.:::.:..:: .::.::.. NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE ::.:: :.:.:::::::::..:::::: ::: .:.: ::::::::.::.:.:.: ::. NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV :.: ::....:..:::::....::: ...::. .:.: :::. :::.....:::. . NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK .: :::: ::.::.. ::. : : :::: ::.:::.:.::::::::.::..:::. :: NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF ::.:.:: . :: ::: ::::::::::::::::::.. ... .: . ::::::::::: NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 300 310 320 330 340 350 360 370 pF1KB3 FIRHNRANSILFCGRFSSP ::.:...:.:::::::::: NP_001 FIQHSKTNGILFCGRFSSP 360 370 >>XP_011512976 (OMIM: 173321,613453) PREDICTED: serpin B (376 aa) initn: 1435 init1: 1033 opt: 1569 Z-score: 1858.1 bits: 352.5 E(85289): 9.3e-97 Smith-Waterman score: 1569; 62.8% identity (86.3% similar) in 379 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB3 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL :..:..:.::::. ::: : .:: :.::: ::.:.: ::::: .:::::::.:::: ::. XP_011 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 10 20 30 40 50 70 80 90 100 110 pF1KB3 NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK : :::..::::::::::.::::::: ::::::::.:.:::.:..:: .::.::.. XP_011 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE ::.:: :.:.:::::::::..:::::: ::: .:.: ::::::::.::.:.:.: ::. XP_011 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV :.: ::....:..:::::....::: ...::. .:.: :::. :::.....:::. . XP_011 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK .: :::: ::.::.. ::. : : :::: ::.:::.:.::::::::.::..:::. :: XP_011 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF ::.:.:: . :: ::: ::::::::::::::::::.. ... .: . ::::::::::: XP_011 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 300 310 320 330 340 350 360 370 pF1KB3 FIRHNRANSILFCGRFSSP ::.:...:.:::::::::: XP_011 FIQHSKTNGILFCGRFSSP 360 370 376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:19:06 2016 done: Sat Nov 5 05:19:08 2016 Total Scan time: 8.360 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]