Result of FASTA (ccds) for
pF1KB3690
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3690, 424 aa
1>>>pF1KB3690 424 - 424 aa - 424 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5745+/-0.0013; mu= -4.2268+/- 0.074
mean_var=336.4489+/-78.794, 0's: 0 Z-trim(107.8): 552 B-trim: 240 in 1/52
Lambda= 0.069922
statistics sampled from 9093 (9776) to 9093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.3), width: 16
Scan time: 3.000
The best scores are: opt bits E(32554)
CCDS4454.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 2830 300.1 2.7e-81
CCDS4453.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 2764 293.4 2.7e-79
CCDS43410.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 2542 271.0 1.4e-72
CCDS43409.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 2476 264.3 1.4e-70
CCDS3612.1 MAPK10 gene_id:5602|Hs108|chr4 ( 426) 2423 259.0 6.2e-69
CCDS34026.1 MAPK10 gene_id:5602|Hs108|chr4 ( 464) 2423 259.1 6.6e-69
CCDS7224.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 2373 254.0 2e-67
CCDS7223.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 2341 250.8 1.9e-66
CCDS43247.1 MAPK10 gene_id:5602|Hs108|chr4 ( 422) 2246 241.2 1.5e-63
CCDS7225.1 MAPK8 gene_id:5599|Hs108|chr10 ( 384) 2202 236.7 3e-62
CCDS7226.1 MAPK8 gene_id:5599|Hs108|chr10 ( 384) 2170 233.5 2.8e-61
CCDS82937.1 MAPK10 gene_id:5602|Hs108|chr4 ( 319) 1770 193.0 3.5e-49
CCDS47356.1 MAPK9 gene_id:5601|Hs108|chr5 ( 242) 1470 162.6 3.7e-40
CCDS78103.1 MAPK9 gene_id:5601|Hs108|chr5 ( 214) 1363 151.8 6e-37
CCDS60527.1 MAPK8 gene_id:5599|Hs108|chr10 ( 308) 1232 138.7 7.3e-33
CCDS4816.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 962 111.6 1.3e-24
CCDS4815.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 938 109.2 6.9e-24
CCDS4818.1 MAPK13 gene_id:5603|Hs108|chr6 ( 365) 936 109.0 8e-24
CCDS14090.1 MAPK11 gene_id:5600|Hs108|chr22 ( 364) 923 107.6 2e-23
CCDS4817.1 MAPK14 gene_id:1432|Hs108|chr6 ( 307) 920 107.3 2.2e-23
CCDS14089.1 MAPK12 gene_id:6300|Hs108|chr22 ( 367) 916 106.9 3.3e-23
CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 890 104.3 2e-22
CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 887 104.0 2.5e-22
CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 863 101.6 1.3e-21
CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 ( 816) 843 100.0 9.1e-21
CCDS11224.2 NLK gene_id:51701|Hs108|chr17 ( 527) 717 87.0 4.6e-17
CCDS42148.1 MAPK3 gene_id:5595|Hs108|chr16 ( 335) 685 83.6 3.2e-16
CCDS6409.2 MAPK15 gene_id:225689|Hs108|chr8 ( 544) 685 83.8 4.4e-16
CCDS11207.1 MAPK7 gene_id:5598|Hs108|chr17 ( 677) 657 81.1 3.6e-15
CCDS10147.1 MAPK6 gene_id:5597|Hs108|chr15 ( 721) 551 70.4 6.2e-12
CCDS42437.1 MAPK4 gene_id:5596|Hs108|chr18 ( 587) 539 69.1 1.3e-11
CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 ( 305) 513 66.2 5e-11
CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 ( 298) 509 65.8 6.5e-11
>>CCDS4454.1 MAPK9 gene_id:5601|Hs108|chr5 (424 aa)
initn: 2830 init1: 2830 opt: 2830 Z-score: 1573.0 bits: 300.1 E(32554): 2.7e-81
Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
370 380 390 400 410 420
pF1KB3 EGCR
::::
CCDS44 EGCR
>>CCDS4453.1 MAPK9 gene_id:5601|Hs108|chr5 (424 aa)
initn: 2764 init1: 2764 opt: 2764 Z-score: 1537.0 bits: 293.4 E(32554): 2.7e-79
Smith-Waterman score: 2764; 97.9% identity (98.8% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::::::::::.:.: :.: : :.::::::::::
CCDS44 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
370 380 390 400 410 420
pF1KB3 EGCR
::::
CCDS44 EGCR
>>CCDS43410.1 MAPK9 gene_id:5601|Hs108|chr5 (382 aa)
initn: 2542 init1: 2542 opt: 2542 Z-score: 1416.5 bits: 271.0 E(32554): 1.4e-72
Smith-Waterman score: 2542; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
:::::::::::::::::
CCDS43 MDWEERSKNGVVKDQPSAQMQQ
370 380
>>CCDS43409.1 MAPK9 gene_id:5601|Hs108|chr5 (382 aa)
initn: 2476 init1: 2476 opt: 2476 Z-score: 1380.5 bits: 264.3 E(32554): 1.4e-70
Smith-Waterman score: 2476; 97.6% identity (98.7% similar) in 377 aa overlap (1-377:1-377)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::::::::::.:.: :.: : :.::::::::::
CCDS43 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
:::::::::::::::::
CCDS43 MDWEERSKNGVVKDQPSAQMQQ
370 380
>>CCDS3612.1 MAPK10 gene_id:5602|Hs108|chr4 (426 aa)
initn: 2255 init1: 2255 opt: 2423 Z-score: 1351.1 bits: 259.0 E(32554): 6.2e-69
Smith-Waterman score: 2423; 85.4% identity (94.1% similar) in 426 aa overlap (1-424:1-426)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
:: :: :.:::::.:.:::::::::::.:::::::::::::::.:.:: :::.::::::
CCDS36 MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::.
CCDS36 FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.:
CCDS36 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::::::::::.::: ::.:::::::::::::::::
CCDS36 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
:::: :::::::::::::::::::: :. : .:::: .::..::..:.:.:::::::::
CCDS36 LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
:::::: ::::::.::.::::.:::::::.::::::::: ::.::::.::::::::::::
CCDS36 MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 MDWEERSKNGVVKDQPSD--AAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTG
:. ::..:::::: ::: :::.:. . :::.::::::::.:::::::::::.::.:
CCDS36 MNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAG
370 380 390 400 410 420
420
pF1KB3 PLEGCR
:: ::
CCDS36 PLGCCR
>>CCDS34026.1 MAPK10 gene_id:5602|Hs108|chr4 (464 aa)
initn: 2255 init1: 2255 opt: 2423 Z-score: 1350.6 bits: 259.1 E(32554): 6.6e-69
Smith-Waterman score: 2423; 85.4% identity (94.1% similar) in 426 aa overlap (1-424:39-464)
10 20 30
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLK
:: :: :.:::::.:.:::::::::::.::
CCDS34 CSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 PIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLN
:::::::::::::.:.:: :::.::::::::::::::::::::::.:::::::::::::
CCDS34 PIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 VFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS34 VFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 DLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWS
:::::::::::::::::::::::::: :.:::::::::::::::::::::::::::::::
CCDS34 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 VGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIK
:::::.::: ::.::::::::::::::::::::: :::::::::::::::::::: :.
CCDS34 VGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEA
: .:::: .::..::..:.:.::::::::::::::: ::::::.::.::::.:::::::.
CCDS34 FPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEV
310 320 330 340 350 360
340 350 360 370 380
pF1KB3 EAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSD--AAVSSNATPS
::::::::: ::.::::.:::::::::::::. ::..:::::: ::: :::.:. .
CCDS34 EAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLP
370 380 390 400 410 420
390 400 410 420
pF1KB3 QSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR
:::.::::::::.:::::::::::.::.::: ::
CCDS34 PSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
430 440 450 460
>>CCDS7224.1 MAPK8 gene_id:5599|Hs108|chr10 (427 aa)
initn: 2376 init1: 2200 opt: 2373 Z-score: 1323.8 bits: 254.0 E(32554): 2e-67
Smith-Waterman score: 2373; 82.2% identity (94.1% similar) in 427 aa overlap (1-424:1-427)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
:: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.::::::
CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::.
CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.:
CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::.:::::::.::: ::.:::::::::::::::::
CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
:::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.:::::::::
CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.::::::::::::
CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 MDWEERSKNGVVKDQPSD---AAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDAST
:: :::.::::.. ::: :..... ::.:::.::.:::::. ::::::::::.:..
CCDS72 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA
370 380 390 400 410 420
420
pF1KB3 GPLEGCR
::: ::
CCDS72 GPLGCCR
>>CCDS7223.1 MAPK8 gene_id:5599|Hs108|chr10 (427 aa)
initn: 2344 init1: 2168 opt: 2341 Z-score: 1306.3 bits: 250.8 E(32554): 1.9e-66
Smith-Waterman score: 2341; 81.5% identity (93.4% similar) in 427 aa overlap (1-424:1-427)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
:: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.::::::
CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::.
CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.:
CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::::::::::.::. ::::: :.::::::::::
CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
:::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.:::::::::
CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.::::::::::::
CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 MDWEERSKNGVVKDQPSD---AAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDAST
:: :::.::::.. ::: :..... ::.:::.::.:::::. ::::::::::.:..
CCDS72 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA
370 380 390 400 410 420
420
pF1KB3 GPLEGCR
::: ::
CCDS72 GPLGCCR
>>CCDS43247.1 MAPK10 gene_id:5602|Hs108|chr4 (422 aa)
initn: 2246 init1: 2246 opt: 2246 Z-score: 1254.6 bits: 241.2 E(32554): 1.5e-63
Smith-Waterman score: 2246; 87.4% identity (95.5% similar) in 380 aa overlap (1-380:39-418)
10 20 30
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLK
:: :: :.:::::.:.:::::::::::.::
CCDS43 CSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 PIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLN
:::::::::::::.:.:: :::.::::::::::::::::::::::.:::::::::::::
CCDS43 PIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 VFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS43 VFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 DLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWS
:::::::::::::::::::::::::: :.:::::::::::::::::::::::::::::::
CCDS43 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 VGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIK
:::::.::: ::.::::::::::::::::::::: :::::::::::::::::::: :.
CCDS43 VGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEA
: .:::: .::..::..:.:.::::::::::::::: ::::::.::.::::.:::::::.
CCDS43 FPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 EAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAVSSNATPSQS
::::::::: ::.::::.:::::::::::::. ::..:::::: ::: .:
CCDS43 EAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSAQVQQ
370 380 390 400 410 420
400 410 420
pF1KB3 SSINDISSMSTEQTLASDTDSSLDASTGPLEGCR
>>CCDS7225.1 MAPK8 gene_id:5599|Hs108|chr10 (384 aa)
initn: 2202 init1: 2202 opt: 2202 Z-score: 1231.1 bits: 236.7 E(32554): 3e-62
Smith-Waterman score: 2202; 85.0% identity (95.3% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
:: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.::::::
CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::.
CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.:
CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
:::::::::::::::::::::::::::.:::::::.::: ::.:::::::::::::::::
CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
:::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.:::::::::
CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.::::::::::::
CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
:: :::.::::.. ::: :
CCDS72 MDLEERTKNGVIRGQPSPLAQVQQ
370 380
424 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:42:02 2016 done: Thu Nov 3 13:42:03 2016
Total Scan time: 3.000 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]