FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3690, 424 aa 1>>>pF1KB3690 424 - 424 aa - 424 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.2811+/-0.00063; mu= -28.0477+/- 0.038 mean_var=851.0571+/-188.340, 0's: 0 Z-trim(115.5): 957 B-trim: 1479 in 1/59 Lambda= 0.043964 statistics sampled from 24836 (26059) to 24836 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.306), width: 16 Scan time: 9.080 The best scores are: opt bits E(85289) XP_016865127 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 2830 195.8 1.8e-49 NP_620709 (OMIM: 602896) mitogen-activated protein ( 424) 2830 195.8 1.8e-49 NP_002743 (OMIM: 602896) mitogen-activated protein ( 424) 2764 191.6 3.2e-48 XP_006714954 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 2764 191.6 3.2e-48 XP_016865129 (OMIM: 602896) PREDICTED: mitogen-act ( 398) 2557 178.4 2.8e-44 NP_620708 (OMIM: 602896) mitogen-activated protein ( 382) 2542 177.5 5.2e-44 XP_016865128 (OMIM: 602896) PREDICTED: mitogen-act ( 398) 2491 174.3 5e-43 XP_005265997 (OMIM: 602896) PREDICTED: mitogen-act ( 398) 2491 174.3 5e-43 XP_016865131 (OMIM: 602896) PREDICTED: mitogen-act ( 378) 2476 173.3 9.4e-43 NP_620707 (OMIM: 602896) mitogen-activated protein ( 382) 2476 173.3 9.5e-43 XP_016865130 (OMIM: 602896) PREDICTED: mitogen-act ( 382) 2476 173.3 9.5e-43 XP_016863913 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_011530422 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_006714331 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_016863912 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_011530423 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_016863915 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 NP_620446 (OMIM: 602897) mitogen-activated protein ( 426) 2423 170.0 1e-41 XP_016863914 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2423 170.0 1e-41 XP_005263187 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 NP_620448 (OMIM: 602897) mitogen-activated protein ( 464) 2423 170.0 1.1e-41 XP_016863909 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 XP_016863910 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 XP_005263186 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 XP_016863908 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 XP_011530419 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 XP_011530420 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2423 170.0 1.1e-41 NP_001304998 (OMIM: 602897) mitogen-activated prot ( 478) 2423 170.0 1.1e-41 XP_016863917 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2387 167.7 5.1e-41 XP_016863916 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 2387 167.7 5.1e-41 NP_001304996 (OMIM: 602897) mitogen-activated prot ( 464) 2387 167.7 5.4e-41 XP_005263188 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 2387 167.7 5.4e-41 NP_001310257 (OMIM: 601158) mitogen-activated prot ( 427) 2373 166.8 9.4e-41 NP_620637 (OMIM: 601158) mitogen-activated protein ( 427) 2373 166.8 9.4e-41 NP_001310260 (OMIM: 601158) mitogen-activated prot ( 427) 2373 166.8 9.4e-41 NP_001310258 (OMIM: 601158) mitogen-activated prot ( 427) 2373 166.8 9.4e-41 NP_001310251 (OMIM: 601158) mitogen-activated prot ( 427) 2341 164.8 3.8e-40 NP_001310252 (OMIM: 601158) mitogen-activated prot ( 427) 2341 164.8 3.8e-40 NP_001310259 (OMIM: 601158) mitogen-activated prot ( 427) 2341 164.8 3.8e-40 NP_001265476 (OMIM: 601158) mitogen-activated prot ( 427) 2341 164.8 3.8e-40 XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 2246 158.7 2.3e-38 XP_016863920 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 2246 158.8 2.5e-38 XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 2246 158.8 2.5e-38 XP_016863918 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 2246 158.8 2.5e-38 XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 2246 158.8 2.5e-38 >>XP_016865127 (OMIM: 602896) PREDICTED: mitogen-activat (424 aa) initn: 2830 init1: 2830 opt: 2830 Z-score: 1009.3 bits: 195.8 E(85289): 1.8e-49 Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL 370 380 390 400 410 420 pF1KB3 EGCR :::: XP_016 EGCR >>NP_620709 (OMIM: 602896) mitogen-activated protein kin (424 aa) initn: 2830 init1: 2830 opt: 2830 Z-score: 1009.3 bits: 195.8 E(85289): 1.8e-49 Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL 370 380 390 400 410 420 pF1KB3 EGCR :::: NP_620 EGCR >>NP_002743 (OMIM: 602896) mitogen-activated protein kin (424 aa) initn: 2764 init1: 2764 opt: 2764 Z-score: 986.7 bits: 191.6 E(85289): 3.2e-48 Smith-Waterman score: 2764; 97.9% identity (98.8% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::.:.: :.: : :.:::::::::: NP_002 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL 370 380 390 400 410 420 pF1KB3 EGCR :::: NP_002 EGCR >>XP_006714954 (OMIM: 602896) PREDICTED: mitogen-activat (424 aa) initn: 2764 init1: 2764 opt: 2764 Z-score: 986.7 bits: 191.6 E(85289): 3.2e-48 Smith-Waterman score: 2764; 97.9% identity (98.8% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::.:.: :.: : :.:::::::::: XP_006 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL 370 380 390 400 410 420 pF1KB3 EGCR :::: XP_006 EGCR >>XP_016865129 (OMIM: 602896) PREDICTED: mitogen-activat (398 aa) initn: 2557 init1: 2557 opt: 2557 Z-score: 916.1 bits: 178.4 E(85289): 2.8e-44 Smith-Waterman score: 2557; 100.0% identity (100.0% similar) in 383 aa overlap (42-424:16-398) 20 30 40 50 60 70 pF1KB3 SVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAY :::::::::::::::::::::::::::::: XP_016 MVRRSAAAASRASSSAAFDTVLGINVAVKKLSRPFQNQTHAKRAY 10 20 30 40 80 90 100 110 120 130 pF1KB3 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB3 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB3 RAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKK 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB3 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB3 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV 290 300 310 320 330 340 380 390 400 410 420 pF1KB3 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR 350 360 370 380 390 >>NP_620708 (OMIM: 602896) mitogen-activated protein kin (382 aa) initn: 2542 init1: 2542 opt: 2542 Z-score: 911.1 bits: 177.5 E(85289): 5.2e-44 Smith-Waterman score: 2542; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL ::::::::::::::::: NP_620 MDWEERSKNGVVKDQPSAQMQQ 370 380 >>XP_016865128 (OMIM: 602896) PREDICTED: mitogen-activat (398 aa) initn: 2491 init1: 2491 opt: 2491 Z-score: 893.4 bits: 174.3 E(85289): 5e-43 Smith-Waterman score: 2491; 97.7% identity (98.7% similar) in 383 aa overlap (42-424:16-398) 20 30 40 50 60 70 pF1KB3 SVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAY :::::::::::::::::::::::::::::: XP_016 MVRRSAAAASRASSSAAFDTVLGINVAVKKLSRPFQNQTHAKRAY 10 20 30 40 80 90 100 110 120 130 pF1KB3 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB3 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB3 RAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKK ::::::::::::::::::::::::.:.: :.: : :.::::::::::::::::::::: XP_016 RAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKK 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB3 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB3 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV 290 300 310 320 330 340 380 390 400 410 420 pF1KB3 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR 350 360 370 380 390 >>XP_005265997 (OMIM: 602896) PREDICTED: mitogen-activat (398 aa) initn: 2491 init1: 2491 opt: 2491 Z-score: 893.4 bits: 174.3 E(85289): 5e-43 Smith-Waterman score: 2491; 97.7% identity (98.7% similar) in 383 aa overlap (42-424:16-398) 20 30 40 50 60 70 pF1KB3 SVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAY :::::::::::::::::::::::::::::: XP_005 MVRRSAAAASRASSSAAFDTVLGINVAVKKLSRPFQNQTHAKRAY 10 20 30 40 80 90 100 110 120 130 pF1KB3 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYL 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB3 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYY 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB3 RAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKK ::::::::::::::::::::::::.:.: :.: : :.::::::::::::::::::::: XP_005 RAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKK 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB3 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB3 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGV 290 300 310 320 330 340 380 390 400 410 420 pF1KB3 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR 350 360 370 380 390 >>XP_016865131 (OMIM: 602896) PREDICTED: mitogen-activat (378 aa) initn: 2476 init1: 2476 opt: 2476 Z-score: 888.5 bits: 173.3 E(85289): 9.4e-43 Smith-Waterman score: 2476; 97.6% identity (98.7% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::.:.: :.: : :.:::::::::: XP_016 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL ::::::::::::::::: XP_016 MDWEERSKNGVVKDQPSG 370 >>NP_620707 (OMIM: 602896) mitogen-activated protein kin (382 aa) initn: 2476 init1: 2476 opt: 2476 Z-score: 888.5 bits: 173.3 E(85289): 9.5e-43 Smith-Waterman score: 2476; 97.6% identity (98.7% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB3 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ :::::::::::::::::::::::::::::::::::.:.: :.: : :.:::::::::: NP_620 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL ::::::::::::::::: NP_620 MDWEERSKNGVVKDQPSAQMQQ 370 380 424 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:42:03 2016 done: Thu Nov 3 13:42:05 2016 Total Scan time: 9.080 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]