FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3698, 375 aa 1>>>pF1KB3698 375 - 375 aa - 375 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1782+/-0.000938; mu= 12.2416+/- 0.056 mean_var=135.0703+/-43.219, 0's: 0 Z-trim(106.4): 212 B-trim: 1150 in 2/46 Lambda= 0.110356 statistics sampled from 8541 (8950) to 8541 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.275), width: 16 Scan time: 2.780 The best scores are: opt bits E(32554) CCDS5322.1 GPER1 gene_id:2852|Hs108|chr7 ( 375) 2492 408.8 4.1e-114 CCDS2409.1 CXCR1 gene_id:3577|Hs108|chr2 ( 350) 488 89.7 4.3e-18 CCDS2684.1 CCR8 gene_id:1237|Hs108|chr3 ( 355) 476 87.8 1.6e-17 CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 355) 476 87.8 1.6e-17 CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 387) 476 87.8 1.7e-17 CCDS9412.1 CYSLTR2 gene_id:57105|Hs108|chr13 ( 346) 465 86.0 5.4e-17 CCDS2408.1 CXCR2 gene_id:3579|Hs108|chr2 ( 360) 464 85.9 6.2e-17 CCDS2656.1 CCR4 gene_id:1233|Hs108|chr3 ( 360) 438 81.7 1.1e-15 CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 ( 360) 430 80.5 2.6e-15 CCDS2737.1 CCR1 gene_id:1230|Hs108|chr3 ( 355) 423 79.3 5.7e-15 CCDS5298.1 CCR6 gene_id:1235|Hs108|chr6 ( 374) 419 78.7 9.1e-15 CCDS43078.1 CCR2 gene_id:729230|Hs108|chr3 ( 374) 414 77.9 1.6e-14 CCDS10429.1 SSTR5 gene_id:6755|Hs108|chr16 ( 364) 413 77.8 1.7e-14 CCDS14416.1 CXCR3 gene_id:2833|Hs108|chrX ( 368) 412 77.6 2e-14 CCDS48135.1 CXCR3 gene_id:2833|Hs108|chrX ( 415) 412 77.7 2.1e-14 CCDS54574.1 CCR3 gene_id:1232|Hs108|chr3 ( 376) 409 77.1 2.8e-14 CCDS3075.1 ACKR4 gene_id:51554|Hs108|chr3 ( 350) 408 76.9 2.9e-14 CCDS46420.1 CXCR4 gene_id:7852|Hs108|chr2 ( 352) 404 76.3 4.6e-14 CCDS2738.1 CCR3 gene_id:1232|Hs108|chr3 ( 355) 404 76.3 4.6e-14 CCDS33295.1 CXCR4 gene_id:7852|Hs108|chr2 ( 356) 404 76.3 4.6e-14 CCDS2148.1 GPR17 gene_id:2840|Hs108|chr2 ( 367) 401 75.9 6.6e-14 CCDS2739.1 CCR5 gene_id:1234|Hs108|chr3 ( 352) 395 74.9 1.2e-13 CCDS2735.1 CXCR6 gene_id:10663|Hs108|chr3 ( 342) 390 74.1 2.1e-13 CCDS8402.1 CXCR5 gene_id:643|Hs108|chr11 ( 372) 385 73.3 3.9e-13 CCDS8927.1 GPR182 gene_id:11318|Hs108|chr12 ( 404) 373 71.4 1.5e-12 CCDS2516.1 ACKR3 gene_id:57007|Hs108|chr2 ( 362) 368 70.6 2.5e-12 CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 ( 388) 368 70.6 2.6e-12 CCDS14439.1 CYSLTR1 gene_id:10800|Hs108|chrX ( 337) 360 69.3 5.7e-12 CCDS2706.1 ACKR2 gene_id:1238|Hs108|chr3 ( 384) 359 69.2 7e-12 CCDS2931.1 GPR15 gene_id:2838|Hs108|chr3 ( 360) 355 68.5 1e-11 CCDS5321.1 GPR146 gene_id:115330|Hs108|chr7 ( 333) 350 67.7 1.7e-11 CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 ( 370) 348 67.4 2.3e-11 CCDS11810.1 UTS2R gene_id:2837|Hs108|chr17 ( 389) 341 66.3 5.1e-11 CCDS33063.1 C5AR1 gene_id:728|Hs108|chr19 ( 350) 339 66.0 6e-11 CCDS77026.1 CCR7 gene_id:1236|Hs108|chr17 ( 372) 338 65.8 6.9e-11 CCDS11369.1 CCR7 gene_id:1236|Hs108|chr17 ( 378) 338 65.8 7e-11 CCDS56174.1 GPR35 gene_id:2859|Hs108|chr2 ( 340) 337 65.6 7.3e-11 CCDS9482.1 OXGR1 gene_id:27199|Hs108|chr13 ( 337) 335 65.3 9e-11 >>CCDS5322.1 GPER1 gene_id:2852|Hs108|chr7 (375 aa) initn: 2492 init1: 2492 opt: 2492 Z-score: 2162.2 bits: 408.8 E(32554): 4.1e-114 Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375) 10 20 30 40 50 60 pF1KB3 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI 310 320 330 340 350 360 370 pF1KB3 PDSTEQSDVRFSSAV ::::::::::::::: CCDS53 PDSTEQSDVRFSSAV 370 >>CCDS2409.1 CXCR1 gene_id:3577|Hs108|chr2 (350 aa) initn: 448 init1: 166 opt: 488 Z-score: 438.3 bits: 89.7 E(32554): 4.3e-18 Smith-Waterman score: 488; 31.6% identity (65.8% similar) in 275 aa overlap (68-332:48-313) 40 50 60 70 80 90 pF1KB3 LGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLY ..: ....:: :...: . : .. :.: CCDS24 TGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVY 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB3 FINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYI ..:::.:::... : . . . . . :: .::. .::.::....:. .: :::. CCDS24 LLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYL 80 90 100 110 120 130 160 170 180 190 200 210 pF1KB3 ALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPF----TAVHLQHTDEACFCFADVRE :...: : .: . .: ... : : :.. .: :: : : .... .:. CCDS24 AIVHATR-TLTQKRHLVKFVCLGCWGLSMNLSL-PFFLFRQAYHPNNSSPVCYEVLGNDT 140 150 160 170 180 190 220 230 240 250 260 pF1KB3 VQWLEV------TLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALRMILAVVLV ..: : :.:::::. .. .::.. .:.: .:: . ...:.:.:.::::. CCDS24 AKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQ-----KHRAMRVIFAVVLI 200 210 220 230 240 250 270 280 290 300 310 320 pF1KB3 FFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLIYSFL :..:::: :. . . :.::: :.. .. : . ... .: .:::::.::.:. CCDS24 FLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDA--TEILGFLHSCLNPIIYAFI 260 270 280 290 300 330 340 350 360 370 pF1KB3 GETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :..:: CCDS24 GQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL 310 320 330 340 350 >>CCDS2684.1 CCR8 gene_id:1237|Hs108|chr3 (355 aa) initn: 308 init1: 308 opt: 476 Z-score: 427.9 bits: 87.8 E(32554): 1.6e-17 Smith-Waterman score: 476; 29.4% identity (63.4% similar) in 303 aa overlap (59-349:36-324) 30 40 50 60 70 80 pF1KB3 PELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFR :.:. .: . :: ....:: :...: . . CCDS26 DLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCL-LFVFSLLGNSLVILVLVVCK 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB3 EKMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFL . .: :.:..:::..::..: . .... : ... .:.: .: : ...:::.::. CCDS26 KLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFI 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB3 TWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEA---C : :: :::.:...:. :: . . : .:.... :: .:. . . .... : CCDS26 TLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMAT-IPLLVFYQVASEDGVLQC 130 140 150 160 170 180 210 220 230 240 250 pF1KB3 FCFADVREVQWLEVT------LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALR . : . . ..: : ::...::.:. .:: :.. : : . : . ::.: CCDS26 YSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHN-----KTKAIR 190 200 210 220 230 260 270 280 290 300 310 pF1KB3 MILAVVLVFFVCWLPENVFI---SVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSN ..: ::.. .. :.: :: . :.: .. : : :. . . :.... .:.. CCDS26 LVLIVVIASLLFWVPFNVVLFLTSLHSMH-ILDG---C--SISQQLTYATHVTEIISFTH 240 250 260 270 280 290 320 330 340 350 360 370 pF1KB3 SCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :.::.::.:.:: :. .: : ::. .: CCDS26 CCVNPVIYAFVGEKFKKHLS-EIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSV 300 310 320 330 340 350 CCDS26 DYIL >>CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 (355 aa) initn: 383 init1: 244 opt: 476 Z-score: 427.9 bits: 87.8 E(32554): 1.6e-17 Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:28-308) 30 40 50 60 70 80 pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN :.: .::: .:.. .: ::.:::.:.. . CCDS43 MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL 10 20 30 40 50 90 100 110 120 130 140 pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS . .. .. :.:..:::..::..:: . . ..:. : .: : . :. ..... CCDS43 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD :.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. . CCDS43 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN 120 130 140 150 160 170 210 220 230 240 250 pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR : :..: :: : .:.. :::..:. :.. :: :...: . :. CCDS43 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK----- 180 190 200 210 220 260 270 280 290 300 310 pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA . ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .: CCDS43 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS ::. :::::::.: :: :: : .:: CCDS43 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF 290 300 310 320 330 340 >>CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 (387 aa) initn: 383 init1: 244 opt: 476 Z-score: 427.4 bits: 87.8 E(32554): 1.7e-17 Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:60-340) 30 40 50 60 70 80 pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN :.: .::: .:.. .: ::.:::.:.. . CCDS54 AFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL 30 40 50 60 70 80 90 100 110 120 130 140 pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS . .. .. :.:..:::..::..:: . . ..:. : .: : . :. ..... CCDS54 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG 90 100 110 120 130 140 150 160 170 180 190 200 pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD :.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. . CCDS54 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN 150 160 170 180 190 200 210 220 230 240 250 pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR : :..: :: : .:.. :::..:. :.. :: :...: . :. CCDS54 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK----- 210 220 230 240 250 260 270 280 290 300 310 pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA . ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .: CCDS54 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS ::. :::::::.: :: :: : .:: CCDS54 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF 320 330 340 350 360 370 >>CCDS9412.1 CYSLTR2 gene_id:57105|Hs108|chr13 (346 aa) initn: 377 init1: 151 opt: 465 Z-score: 418.6 bits: 86.0 E(32554): 5.4e-17 Smith-Waterman score: 465; 31.1% identity (66.4% similar) in 289 aa overlap (60-336:40-317) 30 40 50 60 70 80 pF1KB3 ELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFRE :. .: :..: : .:: : . : .. . CCDS94 PSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFF-WGVLGNGLSIYVFLQPYK 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB3 KMTIPDLYFINLAVADLILVADSLIEVFNLHER-----YYDIAVLCTFMSLFLQVNMYSS : : .....:::..::.... .: . . : . :.: : .:: : :::::: CCDS94 KSTSVNVFMLNLAISDLLFIS-TLPFRADYYLRGSNWIFGDLA--CRIMSYSLYVNMYSS 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB3 VFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTD-E ..::: .: :..:... .: . . : . ::.::. ...... . . :. . CCDS94 IYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVT 130 140 150 160 170 180 210 220 230 240 250 pF1KB3 AC-----FCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRVLVRAHR-HRGLRPRRQKA .: . .: .. .... ...: ..:: ...:: ::.:::.... . ::: ..:: CCDS94 SCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKA 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB3 LRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNS : :. ....::.:.:: ... .::: : .. ::. ...: .: . ::: .:. CCDS94 LTTIIITLIIFFLCFLPYHTLRTVHL---TTWKVGLCKDRLHKALVIT---LALAA-ANA 250 260 270 280 290 320 330 340 350 360 370 pF1KB3 CLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :.:::.: : ::.:.:.:. CCDS94 CFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV 300 310 320 330 340 >>CCDS2408.1 CXCR2 gene_id:3579|Hs108|chr2 (360 aa) initn: 456 init1: 176 opt: 464 Z-score: 417.5 bits: 85.9 E(32554): 6.2e-17 Smith-Waterman score: 464; 31.1% identity (64.7% similar) in 286 aa overlap (60-335:50-325) 30 40 50 60 70 80 pF1KB3 ELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFRE :. .:.. .: ....:: :...: . : CCDS24 LSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYAL-VFLLSLLGNSLVMLVILYSRV 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB3 KMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLT .. :.:..:::.:::... : . . . . . :: .::. .::.::....:. CCDS24 GRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLA 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB3 WMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFT----AVHLQHTDEAC .: :::.:...: : .: . .. ... : :: :. .: : .:. .... :: CCDS24 CISVDRYLAIVHATR-TLTQKRYLVKFICLSIWGLSLLLAL-PVLLFRRTVYSSNVSPAC 140 150 160 170 180 190 210 220 230 240 250 pF1KB3 FCFADVREVQW------LEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALR . ..: : ..:::::. :. .::.. .:.: .:: . ...:.: CCDS24 YEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQ-----KHRAMR 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB3 MILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCL .:.::::.:..:::: :. . . :.::: :.. :. . ... .. .::: CCDS24 VIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCER--RNHIDRALDATEILGILHSCL 260 270 280 290 300 320 330 340 350 360 370 pF1KB3 NPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :::::.:.:. :: : CCDS24 NPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL 310 320 330 340 350 360 >>CCDS2656.1 CCR4 gene_id:1233|Hs108|chr3 (360 aa) initn: 204 init1: 204 opt: 438 Z-score: 395.1 bits: 81.7 E(32554): 1.1e-15 Smith-Waterman score: 438; 28.4% identity (63.4% similar) in 303 aa overlap (59-352:40-332) 30 40 50 60 70 80 pF1KB3 PELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFR ::: ::.. .: .:..:: ....: .... CCDS26 TLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSL-VFVFGLLGNSVVVLVLFKYK 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB3 EKMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFL . .. :.:..:::..::..: . . . ... :: ..: . :..::..::. CCDS26 RLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFV 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB3 TWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVP---FTAVHLQHTDEAC ::.:::.:...:. :: .. .. : ..: :.: : :.. . ... : CCDS26 MLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASL-PGFLFSTCYTERNHTYC 130 140 150 160 170 180 210 220 230 240 250 pF1KB3 FCFADVREVQW-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALR .. . : ::.. ::...:..:. .:::.:.:.: . . .. ..::.. CCDS26 KTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEK-----KNKAVK 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB3 MILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCL ::.:::..:. : : :. . .. : . . : .:.. . . .. :: . :: CCDS26 MIFAVVVLFLGFWTPYNIVLFLETLVELEV-LQDC--TFERYLDYAIQATETLAFVHCCL 250 260 270 280 290 320 330 340 350 360 370 pF1KB3 NPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV ::.:: :::: :: . .. .: .: ..: CCDS26 NPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDA 300 310 320 330 340 350 CCDS26 L 360 >>CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 (360 aa) initn: 308 init1: 181 opt: 430 Z-score: 388.2 bits: 80.5 E(32554): 2.6e-15 Smith-Waterman score: 430; 24.1% identity (65.9% similar) in 299 aa overlap (60-352:44-329) 30 40 50 60 70 80 pF1KB3 ELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFRE .: ::.. .: .:::::.:.... :. .. CCDS46 NESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSL-VFIFGFVGNMLVVLILINCKK 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB3 KMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLT . :.:..:::..::... . . . ... ..: ... . ........::. CCDS46 LKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFII 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB3 WMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEACFCFA ...:::.:...:. :: . .. . :...: :.. . .. :. : . : . CCDS46 LLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVC-G 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB3 DVREVQW------LEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALRMILA : .. ::...:. :. .::: :...:.: . .. .:..:.:.:.. CCDS46 PYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEK----KRHRAVRVIFT 200 210 220 230 240 270 280 290 300 310 320 pF1KB3 VVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLI ...:.:. : : :. : .. .:. : . :... . . . .... .... :.::.: CCDS46 IMIVYFLFWTPYNIVILLNTFQEFF-GLSNCESTSQLDQ--ATQVTETLGMTHCCINPII 250 260 270 280 290 300 330 340 350 360 370 pF1KB3 YSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :.:.:: :: : ...... . .::: CCDS46 YAFVGEKFRRYLSVFFRKHIT----KRFCKQCPVFYRETVDGVTSTNTPSTGEQEVSAGL 310 320 330 340 350 360 >>CCDS2737.1 CCR1 gene_id:1230|Hs108|chr3 (355 aa) initn: 283 init1: 122 opt: 423 Z-score: 382.3 bits: 79.3 E(32554): 5.7e-15 Smith-Waterman score: 475; 28.5% identity (67.5% similar) in 295 aa overlap (60-342:36-319) 30 40 50 60 70 80 pF1KB3 ELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFRE .: ::.. .: ::.:::::...: ..... CCDS27 TTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSL-VFVIGLVGNILVVLVLVQYKR 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB3 KMTIPDLYFINLAVADLILVADSLIEV-FNLHERYYDIAVLCTFMSLFLQVNMYSSVFFL .. ..:..:::..::... . . ..:.. . ..: ..: : ...:: .::. CCDS27 LKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFI 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB3 TWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATL--VPFTAVHLQHTDEAC- ...:::.:...:. :: . .. .:: .. :.. . :. .. . : ..: CCDS27 ILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCS 130 140 150 160 170 180 210 220 230 240 250 pF1KB3 --FCFADVRE---VQWLEVTL-GFIVPFAIIGLCYSLIVRVLVRAHRHRGLRP--RRQKA : ..:: : :...: :...:. .. .::. :...:.: :: ...:: CCDS27 LHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLR-------RPNEKKSKA 190 200 210 220 230 260 270 280 290 300 310 pF1KB3 LRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNS .:.:......::. : : :. : . ..: . :.:: :: :. ..... :... CCDS27 VRLIFVIMIIFFLFWTPYNLTILISVFQDFLF-THECEQS-RHLD-LAVQVTEVIAYTHC 240 250 260 270 280 290 320 330 340 350 360 370 pF1KB3 CLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV :.::.::.:.:: :: :: .... CCDS27 CVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAG 300 310 320 330 340 350 375 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:08:54 2016 done: Thu Nov 3 21:08:55 2016 Total Scan time: 2.780 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]