FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3698, 375 aa
1>>>pF1KB3698 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3828+/-0.0004; mu= 16.9271+/- 0.025
mean_var=122.2634+/-33.739, 0's: 0 Z-trim(112.5): 521 B-trim: 1106 in 1/53
Lambda= 0.115991
statistics sampled from 20760 (21445) to 20760 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.251), width: 16
Scan time: 6.920
The best scores are: opt bits E(85289)
NP_001091671 (OMIM: 601805) G-protein coupled estr ( 375) 2492 428.8 1e-119
NP_001035055 (OMIM: 601805) G-protein coupled estr ( 375) 2492 428.8 1e-119
NP_001496 (OMIM: 601805) G-protein coupled estroge ( 375) 2492 428.8 1e-119
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 488 93.4 8.7e-19
NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 476 91.4 3.5e-18
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 476 91.4 3.5e-18
NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 476 91.4 3.5e-18
NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 476 91.4 3.5e-18
NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 476 91.4 3.7e-18
NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 465 89.5 1.2e-17
NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 89.5 1.2e-17
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 464 89.4 1.4e-17
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 464 89.4 1.4e-17
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 464 89.4 1.4e-17
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 464 89.4 1.4e-17
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 464 89.4 1.4e-17
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 464 89.4 1.4e-17
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 438 85.0 2.9e-16
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 438 85.0 2.9e-16
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 430 83.7 7.4e-16
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 430 83.7 7.4e-16
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 423 82.5 1.6e-15
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 419 81.9 2.7e-15
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 419 81.9 2.7e-15
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 414 81.0 4.8e-15
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 413 80.9 5.3e-15
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 413 80.9 5.3e-15
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 412 80.7 6e-15
XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 412 80.7 6.1e-15
XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 412 80.8 6.5e-15
NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 412 80.8 6.5e-15
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 411 80.5 6.8e-15
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 409 80.2 8.7e-15
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 409 80.2 9.2e-15
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 409 80.2 9.2e-15
NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 408 80.0 9.3e-15
NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 408 80.0 9.3e-15
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 404 79.3 1.5e-14
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 404 79.3 1.5e-14
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 404 79.3 1.5e-14
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 404 79.3 1.5e-14
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 404 79.3 1.5e-14
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 404 79.3 1.5e-14
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 401 78.8 2.1e-14
>>NP_001091671 (OMIM: 601805) G-protein coupled estrogen (375 aa)
initn: 2492 init1: 2492 opt: 2492 Z-score: 2270.3 bits: 428.8 E(85289): 1e-119
Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB3 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
310 320 330 340 350 360
370
pF1KB3 PDSTEQSDVRFSSAV
:::::::::::::::
NP_001 PDSTEQSDVRFSSAV
370
>>NP_001035055 (OMIM: 601805) G-protein coupled estrogen (375 aa)
initn: 2492 init1: 2492 opt: 2492 Z-score: 2270.3 bits: 428.8 E(85289): 1e-119
Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB3 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
310 320 330 340 350 360
370
pF1KB3 PDSTEQSDVRFSSAV
:::::::::::::::
NP_001 PDSTEQSDVRFSSAV
370
>>NP_001496 (OMIM: 601805) G-protein coupled estrogen re (375 aa)
initn: 2492 init1: 2492 opt: 2492 Z-score: 2270.3 bits: 428.8 E(85289): 1e-119
Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB3 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
310 320 330 340 350 360
370
pF1KB3 PDSTEQSDVRFSSAV
:::::::::::::::
NP_001 PDSTEQSDVRFSSAV
370
>>NP_000625 (OMIM: 146929,609423) C-X-C chemokine recept (350 aa)
initn: 448 init1: 166 opt: 488 Z-score: 458.3 bits: 93.4 E(85289): 8.7e-19
Smith-Waterman score: 488; 31.6% identity (65.8% similar) in 275 aa overlap (68-332:48-313)
40 50 60 70 80 90
pF1KB3 LGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLY
..: ....:: :...: . : .. :.:
NP_000 TGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVY
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB3 FINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYI
..:::.:::... : . . . . . :: .::. .::.::....:. .: :::.
NP_000 LLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYL
80 90 100 110 120 130
160 170 180 190 200 210
pF1KB3 ALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPF----TAVHLQHTDEACFCFADVRE
:...: : .: . .: ... : : :.. .: :: : : .... .:.
NP_000 AIVHATR-TLTQKRHLVKFVCLGCWGLSMNLSL-PFFLFRQAYHPNNSSPVCYEVLGNDT
140 150 160 170 180 190
220 230 240 250 260
pF1KB3 VQWLEV------TLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALRMILAVVLV
..: : :.:::::. .. .::.. .:.: .:: . ...:.:.:.::::.
NP_000 AKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQ-----KHRAMRVIFAVVLI
200 210 220 230 240 250
270 280 290 300 310 320
pF1KB3 FFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLIYSFL
:..:::: :. . . :.::: :.. .. : . ... .: .:::::.::.:.
NP_000 FLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDA--TEILGFLHSCLNPIIYAFI
260 270 280 290 300
330 340 350 360 370
pF1KB3 GETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV
:..::
NP_000 GQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
310 320 330 340 350
>>NP_001328 (OMIM: 601470,607339,609423,613784) CX3C che (355 aa)
initn: 383 init1: 244 opt: 476 Z-score: 447.4 bits: 91.4 E(85289): 3.5e-18
Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:28-308)
30 40 50 60 70 80
pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN
:.: .::: .:.. .: ::.:::.:.. .
NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL
10 20 30 40 50
90 100 110 120 130 140
pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS
. .. .. :.:..:::..::..:: . . ..:. : .: : . :. .....
NP_001 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD
:.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. .
NP_001 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN
120 130 140 150 160 170
210 220 230 240 250
pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR
: :..: :: : .:.. :::..:. :.. :: :...: . :.
NP_001 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK-----
180 190 200 210 220
260 270 280 290 300 310
pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA
. ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .:
NP_001 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS
::. :::::::.: :: :: : .::
NP_001 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF
290 300 310 320 330 340
>>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa)
initn: 308 init1: 308 opt: 476 Z-score: 447.4 bits: 91.4 E(85289): 3.5e-18
Smith-Waterman score: 476; 29.4% identity (63.4% similar) in 303 aa overlap (59-349:36-324)
30 40 50 60 70 80
pF1KB3 PELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFR
:.:. .: . :: ....:: :...: . .
NP_005 DLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCL-LFVFSLLGNSLVILVLVVCK
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB3 EKMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFL
. .: :.:..:::..::..: . .... : ... .:.: .: : ...:::.::.
NP_005 KLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFI
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB3 TWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEA---C
: :: :::.:...:. :: . . : .:.... :: .:. . . .... :
NP_005 TLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMAT-IPLLVFYQVASEDGVLQC
130 140 150 160 170 180
210 220 230 240 250
pF1KB3 FCFADVREVQWLEVT------LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALR
. : . . ..: : ::...::.:. .:: :.. : : . : . ::.:
NP_005 YSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHN-----KTKAIR
190 200 210 220 230
260 270 280 290 300 310
pF1KB3 MILAVVLVFFVCWLPENVFI---SVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSN
..: ::.. .. :.: :: . :.: .. : : :. . . :.... .:..
NP_005 LVLIVVIASLLFWVPFNVVLFLTSLHSMH-ILDG---C--SISQQLTYATHVTEIISFTH
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB3 SCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV
:.::.::.:.:: :. .: : ::. .:
NP_005 CCVNPVIYAFVGEKFKKHLS-EIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSV
300 310 320 330 340 350
NP_005 DYIL
>>NP_001164642 (OMIM: 601470,607339,609423,613784) CX3C (355 aa)
initn: 383 init1: 244 opt: 476 Z-score: 447.4 bits: 91.4 E(85289): 3.5e-18
Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:28-308)
30 40 50 60 70 80
pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN
:.: .::: .:.. .: ::.:::.:.. .
NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL
10 20 30 40 50
90 100 110 120 130 140
pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS
. .. .. :.:..:::..::..:: . . ..:. : .: : . :. .....
NP_001 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD
:.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. .
NP_001 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN
120 130 140 150 160 170
210 220 230 240 250
pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR
: :..: :: : .:.. :::..:. :.. :: :...: . :.
NP_001 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK-----
180 190 200 210 220
260 270 280 290 300 310
pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA
. ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .:
NP_001 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS
::. :::::::.: :: :: : .::
NP_001 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF
290 300 310 320 330 340
>>NP_001164643 (OMIM: 601470,607339,609423,613784) CX3C (355 aa)
initn: 383 init1: 244 opt: 476 Z-score: 447.4 bits: 91.4 E(85289): 3.5e-18
Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:28-308)
30 40 50 60 70 80
pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN
:.: .::: .:.. .: ::.:::.:.. .
NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL
10 20 30 40 50
90 100 110 120 130 140
pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS
. .. .. :.:..:::..::..:: . . ..:. : .: : . :. .....
NP_001 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD
:.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. .
NP_001 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN
120 130 140 150 160 170
210 220 230 240 250
pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR
: :..: :: : .:.. :::..:. :.. :: :...: . :.
NP_001 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK-----
180 190 200 210 220
260 270 280 290 300 310
pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA
. ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .:
NP_001 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS
::. :::::::.: :: :: : .::
NP_001 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF
290 300 310 320 330 340
>>NP_001164645 (OMIM: 601470,607339,609423,613784) CX3C (387 aa)
initn: 383 init1: 244 opt: 476 Z-score: 446.9 bits: 91.4 E(85289): 3.7e-18
Smith-Waterman score: 476; 33.4% identity (64.2% similar) in 296 aa overlap (56-338:60-340)
30 40 50 60 70 80
pF1KB3 TTSPELNLSHPLLGTALANGTGELSEHQQYVIG-LFLSCLYTIFLFPIGFVGNILILVVN
:.: .::: .:.. .: ::.:::.:.. .
NP_001 AFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSV-IFAIGLVGNLLVVFAL
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB3 ISFREKMTIPDLYFINLAVADLILVAD-SLIEVFNLHERYYDIAVLCTFMSLFLQVNMYS
. .. .. :.:..:::..::..:: . . ..:. : .: : . :. .....
NP_001 TNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNA-MCKFTTAFFFIGFFG
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB3 SVFFLTWMSFDRYIALARAMRCSLFRT-KHHARLSCGLIWMASVSATLVPFTAVHLQHTD
:.::.: .:.:::.:.. : :: .: . .: : .: :.. .. : .. :. .
NP_001 SIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLG-VWAAAILVAAPQFMFTK-QKEN
150 160 170 180 190 200
210 220 230 240 250
pF1KB3 EACFCFADVREVQ---W-----LEVT-LGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPR
: :..: :: : .:.. :::..:. :.. :: :...: . :.
NP_001 E---CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHK-----
210 220 230 240 250
260 270 280 290 300 310
pF1KB3 RQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAA
. ::...:: ::.:::. : : ::.: .. : . : ..:. :. ... .:
NP_001 KAKAIKLILLVVIVFFLFWTPYNVMIFLETL-KLYDFFPSC--DMRKDLRLALSVTETVA
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB3 FSNSCLNPLIYSFLGETFRDKL-RLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFS
::. :::::::.: :: :: : .::
NP_001 FSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNF
320 330 340 350 360 370
>>NP_001295397 (OMIM: 605666) cysteinyl leukotriene rece (346 aa)
initn: 377 init1: 151 opt: 465 Z-score: 437.5 bits: 89.5 E(85289): 1.2e-17
Smith-Waterman score: 465; 31.1% identity (66.4% similar) in 289 aa overlap (60-336:40-317)
30 40 50 60 70 80
pF1KB3 ELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFRE
:. .: :..: : .:: : . : .. .
NP_001 PSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFF-WGVLGNGLSIYVFLQPYK
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB3 KMTIPDLYFINLAVADLILVADSLIEVFNLHER-----YYDIAVLCTFMSLFLQVNMYSS
: : .....:::..::.... .: . . : . :.: : .:: : ::::::
NP_001 KSTSVNVFMLNLAISDLLFIS-TLPFRADYYLRGSNWIFGDLA--CRIMSYSLYVNMYSS
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB3 VFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTD-E
..::: .: :..:... .: . . : . ::.::. ...... . . :. .
NP_001 IYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVT
130 140 150 160 170 180
210 220 230 240 250
pF1KB3 AC-----FCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRVLVRAHR-HRGLRPRRQKA
.: . .: .. .... ...: ..:: ...:: ::.:::.... . ::: ..::
NP_001 SCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKA
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB3 LRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNS
: :. ....::.:.:: ... .::: : .. ::. ...: .: . ::: .:.
NP_001 LTTIIITLIIFFLCFLPYHTLRTVHL---TTWKVGLCKDRLHKALVIT---LALAA-ANA
250 260 270 280 290
320 330 340 350 360 370
pF1KB3 CLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV
:.:::.: : ::.:.:.:.
NP_001 CFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
300 310 320 330 340
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:08:55 2016 done: Thu Nov 3 21:08:56 2016
Total Scan time: 6.920 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]