Result of FASTA (omim) for
pF1KB3701
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3701, 1178 aa
1>>>pF1KB3701 1178 - 1178 aa - 1178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8880+/-0.000451; mu= 15.4448+/- 0.028
mean_var=117.4104+/-23.548, 0's: 0 Z-trim(112.8): 75 B-trim: 161 in 1/52
Lambda= 0.118364
statistics sampled from 21760 (21835) to 21760 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.256), width: 16
Scan time: 15.960
The best scores are: opt bits E(85289)
XP_006718641 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_016873360 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_016873359 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_016873358 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_016873357 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_005274088 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
NP_071504 (OMIM: 266150,608786) pyruvate carboxyla (1178) 7786 1341.8 0
XP_016873361 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
NP_000911 (OMIM: 266150,608786) pyruvate carboxyla (1178) 7786 1341.8 0
XP_005274089 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
XP_011543388 (OMIM: 266150,608786) PREDICTED: pyru (1178) 7786 1341.8 0
NP_001035806 (OMIM: 266150,608786) pyruvate carbox (1178) 7786 1341.8 0
XP_011543389 (OMIM: 266150,608786) PREDICTED: pyru ( 746) 4799 831.6 0
XP_006718642 (OMIM: 266150,608786) PREDICTED: pyru ( 671) 4458 773.4 0
XP_011511294 (OMIM: 210200,609010) PREDICTED: meth ( 687) 1297 233.6 3.3e-60
NP_064551 (OMIM: 210200,609010) methylcrotonoyl-Co ( 725) 1297 233.6 3.5e-60
XP_016876105 (OMIM: 232000,606054) PREDICTED: prop ( 551) 1287 231.8 9.1e-60
XP_016876103 (OMIM: 232000,606054) PREDICTED: prop ( 655) 1288 232.0 9.3e-60
NP_001121164 (OMIM: 232000,606054) propionyl-CoA c ( 702) 1288 232.1 9.8e-60
XP_016876095 (OMIM: 232000,606054) PREDICTED: prop ( 718) 1288 232.1 1e-59
XP_016876104 (OMIM: 232000,606054) PREDICTED: prop ( 624) 1287 231.9 1e-59
XP_005254116 (OMIM: 232000,606054) PREDICTED: prop ( 640) 1287 231.9 1e-59
XP_016876102 (OMIM: 232000,606054) PREDICTED: prop ( 669) 1287 231.9 1.1e-59
XP_016876101 (OMIM: 232000,606054) PREDICTED: prop ( 681) 1287 231.9 1.1e-59
NP_001171475 (OMIM: 232000,606054) propionyl-CoA c ( 681) 1287 231.9 1.1e-59
XP_016876100 (OMIM: 232000,606054) PREDICTED: prop ( 683) 1287 231.9 1.1e-59
XP_016876098 (OMIM: 232000,606054) PREDICTED: prop ( 695) 1287 231.9 1.1e-59
XP_011519395 (OMIM: 232000,606054) PREDICTED: prop ( 699) 1287 231.9 1.1e-59
XP_016876097 (OMIM: 232000,606054) PREDICTED: prop ( 710) 1287 231.9 1.1e-59
XP_016876096 (OMIM: 232000,606054) PREDICTED: prop ( 711) 1287 231.9 1.1e-59
NP_000273 (OMIM: 232000,606054) propionyl-CoA carb ( 728) 1287 231.9 1.1e-59
XP_016876094 (OMIM: 232000,606054) PREDICTED: prop ( 744) 1287 231.9 1.2e-59
XP_011511295 (OMIM: 210200,609010) PREDICTED: meth ( 472) 1192 215.6 6.1e-55
XP_016876099 (OMIM: 232000,606054) PREDICTED: prop ( 689) 1141 206.9 3.5e-52
XP_006713765 (OMIM: 210200,609010) PREDICTED: meth ( 616) 1095 199.1 7.4e-50
XP_016862363 (OMIM: 210200,609010) PREDICTED: meth ( 616) 1095 199.1 7.4e-50
XP_016862364 (OMIM: 210200,609010) PREDICTED: meth ( 616) 1095 199.1 7.4e-50
NP_001280202 (OMIM: 210200,609010) methylcrotonoyl ( 608) 904 166.4 4.8e-40
XP_005257324 (OMIM: 200350,613933) PREDICTED: acet (2268) 519 101.0 8.7e-20
XP_011523006 (OMIM: 200350,613933) PREDICTED: acet (2268) 519 101.0 8.7e-20
NP_942135 (OMIM: 200350,613933) acetyl-CoA carboxy (2268) 519 101.0 8.7e-20
NP_942134 (OMIM: 200350,613933) acetyl-CoA carboxy (2288) 519 101.1 8.8e-20
XP_011523005 (OMIM: 200350,613933) PREDICTED: acet (2346) 519 101.1 8.9e-20
NP_942136 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 519 101.1 8.9e-20
NP_942133 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 519 101.1 8.9e-20
XP_016880044 (OMIM: 200350,613933) PREDICTED: acet (2346) 519 101.1 8.9e-20
XP_011523003 (OMIM: 200350,613933) PREDICTED: acet (2353) 519 101.1 9e-20
XP_006721916 (OMIM: 200350,613933) PREDICTED: acet (2375) 519 101.1 9e-20
XP_016880043 (OMIM: 200350,613933) PREDICTED: acet (2383) 519 101.1 9e-20
NP_942131 (OMIM: 200350,613933) acetyl-CoA carboxy (2383) 519 101.1 9e-20
>>XP_006718641 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_006 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_016873360 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_016 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_016873359 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_016 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_016873358 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_016 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_016873357 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_016 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_005274088 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_005 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>NP_071504 (OMIM: 266150,608786) pyruvate carboxylase, (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
NP_071 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_016873361 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_016 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>NP_000911 (OMIM: 266150,608786) pyruvate carboxylase, (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
NP_000 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
>>XP_005274089 (OMIM: 266150,608786) PREDICTED: pyruvate (1178 aa)
initn: 7786 init1: 7786 opt: 7786 Z-score: 7187.0 bits: 1341.8 E(85289): 0
Smith-Waterman score: 7786; 100.0% identity (100.0% similar) in 1178 aa overlap (1-1178:1-1178)
10 20 30 40 50 60
pF1KB3 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KB3 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
::::::::::::::::::::::::::::::::::::::
XP_005 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
1150 1160 1170
1178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:10:03 2016 done: Sat Nov 5 07:10:05 2016
Total Scan time: 15.960 Total Display time: 0.700
Function used was FASTA [36.3.4 Apr, 2011]