FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3707, 999 aa 1>>>pF1KB3707 999 - 999 aa - 999 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8996+/-0.00112; mu= 1.6535+/- 0.068 mean_var=247.0204+/-48.695, 0's: 0 Z-trim(110.8): 28 B-trim: 0 in 0/53 Lambda= 0.081603 statistics sampled from 11893 (11914) to 11893 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.366), width: 16 Scan time: 4.940 The best scores are: opt bits E(32554) CCDS8408.1 HYOU1 gene_id:10525|Hs108|chr11 ( 999) 6453 773.7 0 CCDS73559.1 HSPH1 gene_id:10808|Hs108|chr13 ( 782) 463 68.4 6.5e-11 >>CCDS8408.1 HYOU1 gene_id:10525|Hs108|chr11 (999 aa) initn: 6453 init1: 6453 opt: 6453 Z-score: 4119.1 bits: 773.7 E(32554): 0 Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999) 10 20 30 40 50 60 pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV 910 920 930 940 950 960 970 980 990 pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL ::::::::::::::::::::::::::::::::::::::: CCDS84 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 970 980 990 >>CCDS73559.1 HSPH1 gene_id:10808|Hs108|chr13 (782 aa) initn: 469 init1: 205 opt: 463 Z-score: 309.4 bits: 68.4 E(32554): 6.5e-11 Smith-Waterman score: 760; 27.9% identity (56.5% similar) in 703 aa overlap (259-940:144-774) 230 240 250 260 270 280 pF1KB3 MFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFN ... :..:: ::: ... .: :.. . :. CCDS73 FSVEQITAMLLTKLKETAENSLKKPVTDCVISVLGTAFDPFLGGKNFDEKLVEHFCAEFK 120 130 140 150 160 170 290 300 310 320 330 340 pF1KB3 EQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMA-QIEGLMDDVDFKAKVTRVE . : :.. . ::. .: .: ..:: ..:.:. . .:: .:.: : ..:..: . CCDS73 TKYK----LDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQ 180 190 200 210 220 350 360 370 380 390 400 pF1KB3 FEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGK ::::::.:.... :. . :.......... : .::::::.: :.: . : ::. .. CCDS73 FEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKD-IST 230 240 250 260 270 280 410 420 430 440 450 460 pF1KB3 NINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKR ..:::::.: : . : : :: ::::. : : ::: .:: . .... :. :.: . CCDS73 TLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV----- 290 300 310 320 330 340 470 480 490 500 510 520 pF1KB3 VLFSRMGPYPQRKVITFNRYSHDFNFHINYGD-LGFLGPE-DLRVFGSQNLTTVKLKGVG ::: : ::.:: : . :... :.: : :: . : ::... : CCDS73 --FSRNHAAPFSKVLTFLRRG-PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQK----- 350 360 370 380 390 530 540 550 560 570 580 pF1KB3 DSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLF : :.. .:.. .. :..... . ..:: ::. ... .. CCDS73 -------DGEKSRVKVKVRVNTHGIFTISTA-----SMVEKVPTEENEMSSEADMECLNQ 400 410 420 430 440 590 600 610 620 630 640 pF1KB3 GGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPE--PKG .::. .: ::... .: : : ... .:. . ...:: :: . CCDS73 RPPENPDTDKN----VQQDN--------SEAGTQPQVQTDAQ---QTSQSPPSPELTSEE 450 460 470 480 650 660 670 680 690 700 pF1KB3 DATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVEL . :...::.::. . ::.::. :. . . : . .: ..: .: CCDS73 NKIPDADKANEKKVDQPPEAKKPKIKVV-------------NVELPIEAN-LVWQLGKDL 490 500 510 520 530 710 720 730 740 750 760 pF1KB3 VVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVS :.. : :. .:: ::: ::. : :..: ...: .::: : :.. CCDS73 --LNMYIETEGKMI-----MQD----KLEK-ERNDAKNAVEEYVYEFRDKLCGP-YEKFI 540 550 560 570 580 770 780 790 800 810 820 pF1KB3 TEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLS :...... :. . :: .:: . .:: :: :. . : .: .. :. . CCDS73 CEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFE 590 600 610 620 630 640 830 840 850 860 870 880 pF1KB3 ALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEK : . :.: . . : : . . : :: .:: .::. : : .. ::: . CCDS73 ELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQD 650 660 670 680 690 700 890 900 910 920 pF1KB3 PVLLSKDIEAKMMALDREVQYLLN--KAKFTKPR----PR-P---------KDKNGTRAE ::. ...:..:. :. . ... : :. .:. : : .:::. :: CCDS73 PVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAE 710 720 730 740 750 760 930 940 950 960 970 980 pF1KB3 PPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQS :: . . .:: CCDS73 PPHQNGECYPNEKNSVNMDLD 770 780 999 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:46:34 2016 done: Thu Nov 3 13:46:35 2016 Total Scan time: 4.940 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]