Result of FASTA (omim) for
pF1KB3707
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3707, 999 aa
1>>>pF1KB3707 999 - 999 aa - 999 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5492+/-0.000478; mu= -2.4290+/- 0.030
mean_var=262.3750+/-53.342, 0's: 0 Z-trim(118.3): 35 B-trim: 306 in 1/56
Lambda= 0.079180
statistics sampled from 31167 (31202) to 31167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.366), width: 16
Scan time: 15.370
The best scores are: opt bits E(85289)
XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 6453 751.3 5.8e-216
XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 6453 751.3 5.8e-216
NP_001124463 (OMIM: 601746) hypoxia up-regulated p ( 999) 6453 751.3 5.8e-216
NP_006380 (OMIM: 601746) hypoxia up-regulated prot ( 999) 6453 751.3 5.8e-216
XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_016875853 (OMIM: 610703) PREDICTED: heat shock ( 736) 463 67.0 4.3e-10
XP_011533190 (OMIM: 610703) PREDICTED: heat shock ( 780) 463 67.0 4.5e-10
NP_001273434 (OMIM: 610703) heat shock protein 105 ( 782) 463 67.0 4.5e-10
XP_016875852 (OMIM: 610703) PREDICTED: heat shock ( 807) 410 61.0 3.1e-08
NP_001273432 (OMIM: 610703) heat shock protein 105 ( 814) 410 61.0 3.1e-08
XP_016875850 (OMIM: 610703) PREDICTED: heat shock ( 851) 410 61.0 3.2e-08
NP_006635 (OMIM: 610703) heat shock protein 105 kD ( 858) 410 61.0 3.2e-08
NP_005518 (OMIM: 140559) heat shock 70 kDa protein ( 641) 406 60.4 3.5e-08
NP_002146 (OMIM: 140555) heat shock 70 kDa protein ( 643) 406 60.4 3.5e-08
NP_694881 (OMIM: 600816) heat shock cognate 71 kDa ( 493) 396 59.2 6.2e-08
NP_006588 (OMIM: 600816) heat shock cognate 71 kDa ( 646) 396 59.3 7.8e-08
XP_011541100 (OMIM: 600816) PREDICTED: heat shock ( 646) 396 59.3 7.8e-08
NP_005336 (OMIM: 140550) heat shock 70 kDa protein ( 641) 392 58.8 1.1e-07
NP_005337 (OMIM: 603012) heat shock 70 kDa protein ( 641) 392 58.8 1.1e-07
NP_068814 (OMIM: 140560) heat shock-related 70 kDa ( 639) 390 58.6 1.2e-07
NP_005338 (OMIM: 138120) 78 kDa glucose-regulated ( 654) 383 57.8 2.2e-07
NP_002145 (OMIM: 601113) heat shock 70 kDa protein ( 840) 383 57.9 2.7e-07
NP_004125 (OMIM: 182170,600548,616854) stress-70 p ( 679) 366 55.9 8.7e-07
NP_008879 (OMIM: 601100) heat shock 70 kDa protein ( 471) 331 51.8 1e-05
XP_016875851 (OMIM: 610703) PREDICTED: heat shock ( 809) 336 52.5 1.1e-05
XP_005266293 (OMIM: 610703) PREDICTED: heat shock ( 816) 336 52.5 1.1e-05
XP_011533189 (OMIM: 610703) PREDICTED: heat shock ( 853) 336 52.5 1.1e-05
NP_001273433 (OMIM: 610703) heat shock protein 105 ( 860) 336 52.5 1.1e-05
NP_057383 (OMIM: 610369) heat shock 70 kDa protein ( 509) 272 45.1 0.0012
>>XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up-regu (999 aa)
initn: 6453 init1: 6453 opt: 6453 Z-score: 3998.2 bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:::::::::::::::::::::::::::::::::::::::
XP_016 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990
>>XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up-regu (999 aa)
initn: 6453 init1: 6453 opt: 6453 Z-score: 3998.2 bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:::::::::::::::::::::::::::::::::::::::
XP_016 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990
>>NP_001124463 (OMIM: 601746) hypoxia up-regulated prote (999 aa)
initn: 6453 init1: 6453 opt: 6453 Z-score: 3998.2 bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:::::::::::::::::::::::::::::::::::::::
NP_001 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990
>>NP_006380 (OMIM: 601746) hypoxia up-regulated protein (999 aa)
initn: 6453 init1: 6453 opt: 6453 Z-score: 3998.2 bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:::::::::::::::::::::::::::::::::::::::
NP_006 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990
>>XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up-regu (1000 aa)
initn: 6439 init1: 6199 opt: 6441 Z-score: 3990.8 bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990 1000
>>XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up-regu (1000 aa)
initn: 6439 init1: 6199 opt: 6441 Z-score: 3990.8 bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990 1000
>>XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up-regu (1000 aa)
initn: 6439 init1: 6199 opt: 6441 Z-score: 3990.8 bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990 1000
>>XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up-regu (1000 aa)
initn: 6439 init1: 6199 opt: 6441 Z-score: 3990.8 bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)
10 20 30 40 50 60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
910 920 930 940 950 960
970 980 990
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
:: :::::::::::::::::::::::::::::::::::::
XP_016 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
970 980 990 1000
>>XP_016875853 (OMIM: 610703) PREDICTED: heat shock prot (736 aa)
initn: 554 init1: 205 opt: 463 Z-score: 302.2 bits: 67.0 E(85289): 4.3e-10
Smith-Waterman score: 658; 24.9% identity (50.6% similar) in 927 aa overlap (33-940:1-728)
10 20 30 40 50 60
pF1KB3 DKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNK
..:...:.::.: .:... : .: . :.
XP_016 MSVVGLDVGSQSCYIAVARAG-GIETIANE
10 20
70 80 90 100 110 120
pF1KB3 ESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPE
: : :: .... ..: .: .: .. : . . :. :... :. ..: .
XP_016 FSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFI---------
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB3 HELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQ
:.. ...:. :.. :.:.. . . :..
XP_016 -------QKE------------------------KENLSYDLV--PLKNGGVGIKVMYMG
90 100
190 200 210 220 230 240
pF1KB3 AERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTI
:. ..: :. :: :. .. ::.: .. . : :.:
XP_016 EEHL----------FSVEQI----TAMLLT-------KLKETAEN----SLKKPVTDCVI
110 120 130 140
250 260 270 280 290 300
pF1KB3 VTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVREN
.. :..:: ::: ... .: :.. . :. . : :.. .
XP_016 -----------------SVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSK
150 160 170 180
310 320 330 340 350 360
pF1KB3 PRAMAKLLREANRLKTVLSANADHMA-QIEGLMDDVDFKAKVTRVEFEELCADLFERVPG
::. .: .: ..:: ..:.:. . .:: .:.: : ..:..: .::::::.:....
XP_016 IRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEV
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB3 PVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVY
:. . :.......... : .::::::.: :.: . : ::. .. ..:::::.: : .
XP_016 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKD-ISTTLNADEAVARGCAL
250 260 270 280 290 300
430 440 450 460 470 480
pF1KB3 QAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKV
: : :: ::::. : : ::: .:: . .... :. :.: . ::: : ::
XP_016 QCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV-------FSRNHAAPFSKV
310 320 330 340 350
490 500 510 520 530
pF1KB3 ITFNRYSHDFNFHINYGD-LGFLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGI
.:: : . :... :.: : :: . : ::... : : :.. .
XP_016 LTFLRRG-PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQK------------DGEKSRV
360 370 380 390 400
540 550 560 570 580 590
pF1KB3 KAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTD
:.. .. :..... . ..:: :: : .::
XP_016 KVKVRVNTHGIFTISTA-----SMVEKVPTEE-------NEMSS----------------
410 420 430
600 610 620 630 640 650
pF1KB3 TVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGD
:: .: .: :: .: ::. ::. .
XP_016 ---------------------------EADMECLNQRPPENPDTDAN-------EKKVDQ
440 450
660 670 680 690 700 710
pF1KB3 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS
::.::. :. . . : . .: ..: .: :.. : :.
XP_016 PPEAKKPKIKVV-------------NVELPI-EANLVWQLGKDL--LNMYIETEGKMI--
460 470 480 490 500
720 730 740 750 760 770
pF1KB3 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS
.:: ::: ::. : :..: ...: .::: : :.. :...... :. .
XP_016 ---MQD----KLEK-ERNDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTETE
510 520 530 540 550
780 790 800 810 820 830
pF1KB3 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGA
:: .:: . .:: :: :. . : .: .. :. . : . :.: . .
XP_016 DWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADF
560 570 580 590 600 610
840 850 860 870 880 890
pF1KB3 RLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALD
: : . . : :: .:: .::. : : .. ::: . ::. ...:..:. :.
XP_016 RNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELN
620 630 640 650 660 670
900 910 920 930 940
pF1KB3 REVQYLLN--KAKFTKPR----PR-P---------KDKNGTRAEPPLNASASDQGEKVIP
. ... : :. .:. : : .:::. :::: . . .::
XP_016 NTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSV
680 690 700 710 720 730
950 960 970 980 990
pF1KB3 PAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
XP_016 NMDLD
>>XP_011533190 (OMIM: 610703) PREDICTED: heat shock prot (780 aa)
initn: 469 init1: 205 opt: 463 Z-score: 301.8 bits: 67.0 E(85289): 4.5e-10
Smith-Waterman score: 764; 25.3% identity (53.4% similar) in 929 aa overlap (33-940:1-772)
10 20 30 40 50 60
pF1KB3 DKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNK
..:...:.::.: .:... : .: . :.
XP_011 MSVVGLDVGSQSCYIAVARAG-GIETIANE
10 20
70 80 90 100 110 120
pF1KB3 ESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPE
: : :: .... ..: .: .: .. : . . :. :... :. ..: .
XP_011 FSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFI---------
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB3 HELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQ
:.. ...:. :.. :.:.. . . :..
XP_011 -------QKE------------------------KENLSYDLV--PLKNGGVGIKVMYMG
90 100
190 200 210 220 230 240
pF1KB3 AERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTI
:. ..: :. :: :. .. ::.: .. . : :.:
XP_011 EEHL----------FSVEQI----TAMLLT-------KLKETAEN----SLKKPVTDCVI
110 120 130 140
250 260 270 280 290 300
pF1KB3 VTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVREN
.. :..:: ::: ... .: :.. . :. . : :.. .
XP_011 -----------------SVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSK
150 160 170 180
310 320 330 340 350 360
pF1KB3 PRAMAKLLREANRLKTVLSANADHMA-QIEGLMDDVDFKAKVTRVEFEELCADLFERVPG
::. .: .: ..:: ..:.:. . .:: .:.: : ..:..: .::::::.:....
XP_011 IRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEV
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB3 PVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVY
:. . :.......... : .::::::.: :.: . : ::. .. ..:::::.: : .
XP_011 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKD-ISTTLNADEAVARGCAL
250 260 270 280 290 300
430 440 450 460 470 480
pF1KB3 QAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKV
: : :: ::::. : : ::: .:: . .... :. :.: . ::: : ::
XP_011 QCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV-------FSRNHAAPFSKV
310 320 330 340 350
490 500 510 520 530
pF1KB3 ITFNRYSHDFNFHINYGD-LGFLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGI
.:: : . :... :.: : :: . : ::... : : :.. .
XP_011 LTFLRRG-PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQK------------DGEKSRV
360 370 380 390 400
540 550 560 570 580 590
pF1KB3 KAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTD
:.. .. :..... . ..:: ::. ... .. .::. .:
XP_011 KVKVRVNTHGIFTISTA-----SMVEKVPTEENEMSSEADMECLNQRPPENPDTDKN---
410 420 430 440 450
600 610 620 630 640 650
pF1KB3 TVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPE--PKGDATPEGEKATEKEN
::... .: : : ... .:. . ...:: :: . . :...::.::.
XP_011 -VQQDN--------SEAGTQPQVQTDAQ---QTSQSPPSPELTSEENKIPDADKANEKKV
460 470 480 490 500
660 670 680 690 700 710
pF1KB3 GDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLA
. ::.::. :. . . : . .: ..: .: :.. : :.
XP_011 DQPPEAKKPKIKVV-------------NVELPI-EANLVWQLGKDL--LNMYIETEGKMI
510 520 530 540
720 730 740 750 760 770
pF1KB3 QSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSA
.:: ::: ::. : :..: ...: .::: : :.. :...... :.
XP_011 -----MQD----KLEK-ERNDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTE
550 560 570 580 590
780 790 800 810 820 830
pF1KB3 ASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLK
. :: .:: . .:: :: :. . : .: .. :. . : . :.: . .
XP_011 TEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAA
600 610 620 630 640 650
840 850 860 870 880 890
pF1KB3 GARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMA
: : . . : :: .:: .::. : : .. ::: . ::. ...:..:.
XP_011 DFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKE
660 670 680 690 700 710
900 910 920 930 940
pF1KB3 LDREVQYLLN--KAKFTKPR----PR-P---------KDKNGTRAEPPLNASASDQGEKV
:. . ... : :. .:. : : .:::. :::: . . .::
XP_011 LNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKN
720 730 740 750 760 770
950 960 970 980 990
pF1KB3 IPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
XP_011 SVNMDLD
780
999 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:46:35 2016 done: Thu Nov 3 13:46:38 2016
Total Scan time: 15.370 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]