FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3761, 1068 aa 1>>>pF1KB3761 1068 - 1068 aa - 1068 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5649+/-0.000433; mu= 15.2999+/- 0.027 mean_var=84.3934+/-17.074, 0's: 0 Z-trim(111.3): 25 B-trim: 0 in 0/51 Lambda= 0.139611 statistics sampled from 19807 (19830) to 19807 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.233), width: 16 Scan time: 14.430 The best scores are: opt bits E(85289) NP_002886 (OMIM: 116957) retinoblastoma-like prote (1068) 7085 1437.8 0 NP_899662 (OMIM: 116957) retinoblastoma-like prote (1014) 6727 1365.7 0 XP_016883481 (OMIM: 116957) PREDICTED: retinoblast ( 964) 6411 1302.0 0 XP_011527257 (OMIM: 116957) PREDICTED: retinoblast (1013) 6341 1287.9 0 XP_006723905 (OMIM: 116957) PREDICTED: retinoblast ( 896) 5846 1188.2 0 XP_011527260 (OMIM: 116957) PREDICTED: retinoblast ( 733) 4809 979.3 0 NP_001310210 (OMIM: 116957) retinoblastoma-like pr ( 641) 4239 864.5 0 NP_001310211 (OMIM: 116957) retinoblastoma-like pr ( 641) 4239 864.5 0 NP_001310539 (OMIM: 180203) retinoblastoma-like pr (1090) 3067 628.5 6.3e-179 NP_001310538 (OMIM: 180203) retinoblastoma-like pr (1115) 2568 528.0 1.2e-148 NP_001310537 (OMIM: 180203) retinoblastoma-like pr (1139) 2568 528.0 1.2e-148 NP_005602 (OMIM: 180203) retinoblastoma-like prote (1139) 2568 528.0 1.2e-148 NP_001310540 (OMIM: 180203) retinoblastoma-like pr (1065) 2469 508.1 1.1e-142 XP_011521555 (OMIM: 180203) PREDICTED: retinoblast ( 923) 1734 360.0 3.6e-98 XP_016879002 (OMIM: 180203) PREDICTED: retinoblast ( 923) 1734 360.0 3.6e-98 XP_011533473 (OMIM: 109800,180200,182280,259500,61 ( 841) 346 80.4 4.7e-14 NP_000312 (OMIM: 109800,180200,182280,259500,61404 ( 928) 346 80.4 5.2e-14 >>NP_002886 (OMIM: 116957) retinoblastoma-like protein 1 (1068 aa) initn: 7085 init1: 7085 opt: 7085 Z-score: 7707.2 bits: 1437.8 E(85289): 0 Smith-Waterman score: 7085; 100.0% identity (100.0% similar) in 1068 aa overlap (1-1068:1-1068) 10 20 30 40 50 60 pF1KB3 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNM 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KB3 IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH :::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH 1030 1040 1050 1060 >>NP_899662 (OMIM: 116957) retinoblastoma-like protein 1 (1014 aa) initn: 6727 init1: 6727 opt: 6727 Z-score: 7317.9 bits: 1365.7 E(85289): 0 Smith-Waterman score: 6727; 100.0% identity (100.0% similar) in 1012 aa overlap (1-1012:1-1012) 10 20 30 40 50 60 pF1KB3 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNM :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKVR 970 980 990 1000 1010 1030 1040 1050 1060 pF1KB3 IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH >>XP_016883481 (OMIM: 116957) PREDICTED: retinoblastoma- (964 aa) initn: 6411 init1: 6411 opt: 6411 Z-score: 6974.3 bits: 1302.0 E(85289): 0 Smith-Waterman score: 6411; 100.0% identity (100.0% similar) in 964 aa overlap (105-1068:1-964) 80 90 100 110 120 130 pF1KB3 VGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTV :::::::::::::::::::::::::::::: XP_016 MKKWMDMSNLPQEFRERIERLERNFEVSTV 10 20 30 140 150 160 170 180 190 pF1KB3 IFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDD 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 LVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCE 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 LHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 DFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGR 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 RYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGI 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 GETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQ 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 DIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKH 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 LNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPM 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 SPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKI 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 ITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITL 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB3 IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRK 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB3 VYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKV 700 710 720 730 740 750 860 870 880 890 900 910 pF1KB3 TKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATK 760 770 780 790 800 810 920 930 940 950 960 970 pF1KB3 TPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPG 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KB3 SPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIA 880 890 900 910 920 930 1040 1050 1060 pF1KB3 IDSDAESPAKRVCQENDDVLLKRLQDVVSERANH :::::::::::::::::::::::::::::::::: XP_016 IDSDAESPAKRVCQENDDVLLKRLQDVVSERANH 940 950 960 >>XP_011527257 (OMIM: 116957) PREDICTED: retinoblastoma- (1013 aa) initn: 6341 init1: 6341 opt: 6341 Z-score: 6897.7 bits: 1287.9 E(85289): 0 Smith-Waterman score: 6579; 94.9% identity (94.9% similar) in 1068 aa overlap (1-1068:1-1013) 10 20 30 40 50 60 pF1KB3 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHM--- 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB3 PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNM :::::::: XP_011 ----------------------------------------------------SLKDINNM 960 1030 1040 1050 1060 pF1KB3 IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH 970 980 990 1000 1010 >>XP_006723905 (OMIM: 116957) PREDICTED: retinoblastoma- (896 aa) initn: 5846 init1: 5846 opt: 5846 Z-score: 6359.8 bits: 1188.2 E(85289): 0 Smith-Waterman score: 5846; 99.8% identity (100.0% similar) in 885 aa overlap (184-1068:12-896) 160 170 180 190 200 210 pF1KB3 PPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANA ..:::::::::::::::::::::::::::: XP_006 MKNHQSYHEAGSRGNFRMIGDDLVNSYHLLLCCLDLIFANA 10 20 30 40 220 230 240 250 260 270 pF1KB3 IMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKP 50 60 70 80 90 100 280 290 300 310 320 330 pF1KB3 YISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTP 110 120 130 140 150 160 340 350 360 370 380 390 pF1KB3 RKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQS 170 180 190 200 210 220 400 410 420 430 440 450 pF1KB3 VSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSH 230 240 250 260 270 280 460 470 480 490 500 510 pF1KB3 IDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAY 290 300 310 320 330 340 520 530 540 550 560 570 pF1KB3 SSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSA 350 360 370 380 390 400 580 590 600 610 620 630 pF1KB3 LWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLR 410 420 430 440 450 460 640 650 660 670 680 690 pF1KB3 RDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAEN 470 480 490 500 510 520 700 710 720 730 740 750 pF1KB3 VSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSL 530 540 550 560 570 580 760 770 780 790 800 810 pF1KB3 TAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVS 590 600 610 620 630 640 820 830 840 850 860 870 pF1KB3 NELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQ 650 660 670 680 690 700 880 890 900 910 920 930 pF1KB3 ANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKF 710 720 730 740 750 760 940 950 960 970 980 990 pF1KB3 YNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNG 770 780 790 800 810 820 1000 1010 1020 1030 1040 1050 pF1KB3 SGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDV 830 840 850 860 870 880 1060 pF1KB3 LLKRLQDVVSERANH ::::::::::::::: XP_006 LLKRLQDVVSERANH 890 >>XP_011527260 (OMIM: 116957) PREDICTED: retinoblastoma- (733 aa) initn: 4809 init1: 4809 opt: 4809 Z-score: 5232.4 bits: 979.3 E(85289): 0 Smith-Waterman score: 4809; 99.7% identity (100.0% similar) in 726 aa overlap (1-726:1-726) 10 20 30 40 50 60 pF1KB3 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN ::::.. XP_011 PLHGLSFGKCTLT 730 >>NP_001310210 (OMIM: 116957) retinoblastoma-like protei (641 aa) initn: 4239 init1: 4239 opt: 4239 Z-score: 4612.9 bits: 864.5 E(85289): 0 Smith-Waterman score: 4239; 100.0% identity (100.0% similar) in 641 aa overlap (428-1068:1-641) 400 410 420 430 440 450 pF1KB3 QSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFA :::::::::::::::::::::::::::::: NP_001 MKILKGIGETFCQHYTQSTDEQPGSHIDFA 10 20 30 460 470 480 490 500 510 pF1KB3 VNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPR 40 50 60 70 80 90 520 530 540 550 560 570 pF1KB3 TFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEA 100 110 120 130 140 150 580 590 600 610 620 630 pF1KB3 LQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQ 160 170 180 190 200 210 640 650 660 670 680 690 pF1KB3 PLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSIL 220 230 240 250 260 270 700 710 720 730 740 750 pF1KB3 PGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHS 280 290 300 310 320 330 760 770 780 790 800 810 pF1KB3 LIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELR 340 350 360 370 380 390 820 830 840 850 860 870 pF1KB3 RKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSH 400 410 420 430 440 450 880 890 900 910 920 930 pF1KB3 VYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTI 460 470 480 490 500 510 940 950 960 970 980 990 pF1KB3 YVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLT 520 530 540 550 560 570 1000 1010 1020 1030 1040 1050 pF1KB3 PRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKR 580 590 600 610 620 630 1060 pF1KB3 LQDVVSERANH ::::::::::: NP_001 LQDVVSERANH 640 >>NP_001310211 (OMIM: 116957) retinoblastoma-like protei (641 aa) initn: 4239 init1: 4239 opt: 4239 Z-score: 4612.9 bits: 864.5 E(85289): 0 Smith-Waterman score: 4239; 100.0% identity (100.0% similar) in 641 aa overlap (428-1068:1-641) 400 410 420 430 440 450 pF1KB3 QSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFA :::::::::::::::::::::::::::::: NP_001 MKILKGIGETFCQHYTQSTDEQPGSHIDFA 10 20 30 460 470 480 490 500 510 pF1KB3 VNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPR 40 50 60 70 80 90 520 530 540 550 560 570 pF1KB3 TFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEA 100 110 120 130 140 150 580 590 600 610 620 630 pF1KB3 LQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQ 160 170 180 190 200 210 640 650 660 670 680 690 pF1KB3 PLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSIL 220 230 240 250 260 270 700 710 720 730 740 750 pF1KB3 PGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHS 280 290 300 310 320 330 760 770 780 790 800 810 pF1KB3 LIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELR 340 350 360 370 380 390 820 830 840 850 860 870 pF1KB3 RKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSH 400 410 420 430 440 450 880 890 900 910 920 930 pF1KB3 VYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTI 460 470 480 490 500 510 940 950 960 970 980 990 pF1KB3 YVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLT 520 530 540 550 560 570 1000 1010 1020 1030 1040 1050 pF1KB3 PRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKR 580 590 600 610 620 630 1060 pF1KB3 LQDVVSERANH ::::::::::: NP_001 LQDVVSERANH 640 >>NP_001310539 (OMIM: 180203) retinoblastoma-like protei (1090 aa) initn: 3384 init1: 1045 opt: 3067 Z-score: 3333.3 bits: 628.5 E(85289): 6.3e-179 Smith-Waterman score: 3504; 50.5% identity (75.0% similar) in 1111 aa overlap (3-1068:26-1090) 10 20 30 pF1KB3 MFEDKPHAEGAAVVAAAG-----EALQALCQELNLDE :: .:: :: : . . .. ::..::.:: NP_001 MPSGGDQSPPPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQIQQRFDELCSRLNMDE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 GSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILR .. ::: :.. .. .:.:::. :::::.::::::::. :::.:: .::: :::::::. NP_001 AARAEAWDSYRSMSESYTLEGNDLHWLACALYVACRKSV-PTVSKGTVEGNYVSLTRILK 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 SAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYE .. :::.::.::::: ::.::: .:::: ::::::: ::.:::::::::: :::. : : NP_001 CSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQE 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB3 EPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFAN : :. :.::::: ::.:...:.:::.::.:.:::: ::.:::::::::::: :::...: NP_001 EQPRQQRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGN 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB3 AIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFK :..: ::..:.::.:::: :::. : : .::::: :: :::::..::::::::..: NP_001 ALQCSNRKELVNPNFKGLSEDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWK 240 250 260 270 280 290 280 290 300 310 320 pF1KB3 PYISKLFDRKILKGEC-----LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAE ::: ::...:.:::. .:. ..: .. ::.:: ::::::.::..::::::: ::: NP_001 PYIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAE 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB3 EEIGTPRKFTRDTPLGKLTAQ-ANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITP ::::: . .. : ::. .... :::::.:.... :::::: ::..:. .:: NP_001 EEIGTLSRCL-NAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTP 360 370 380 390 400 410 390 400 410 420 430 440 pF1KB3 VASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQST :..::.:.:::.....::.::::..: .:...: :.:.. : . :: . : . ::. : NP_001 VSTATHSLSRLHTMLTGLRNAPSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHF-QPD 420 430 440 450 460 470 450 460 470 480 490 500 pF1KB3 DEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCL .. . ..: .....::.::::.::.:. :: .:: ::.: .:::: :::::.:::: NP_001 EDFSNCAKEIASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCL 480 490 500 510 520 530 510 520 530 540 550 560 pF1KB3 EIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESL :.: :.:. : .::.: :.... ..::::::: ::.:.:: :..:::::.::::::. : NP_001 EVVTFSYKPPGNFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHL 540 550 560 570 580 590 570 580 590 600 610 620 pF1KB3 AWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVR ::. .: ::: .. . :.:::::::. :.:.: .. . : ::: :: ::: NP_001 AWKPESPLWEKIRDNENRVPTCEEVMPPQNLERADEICIAG-------SPLTPRRVTEVR 600 610 620 630 640 650 630 640 650 660 670 680 pF1KB3 TDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGE-DPPKEMLMDKIITEGTKLKIAP .:.:.: :.. :: ....::::: :....:::: : : :.. . .. .: NP_001 ADTGGLGRSI--TSPTTLYDRYSSPPASTTRRRLFVENDSPSDGGTPGRMPPQPLVNAVP 660 670 680 690 700 690 700 710 720 730 740 pF1KB3 SSSITAENVSI--LPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQ .....:.::. .:::::.::::: ::...:. ::::..:.::. : ::..:...: NP_001 VQNVSGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVN--- 710 720 730 740 750 760 750 760 770 780 790 800 pF1KB3 ESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLA--LFYRKVYHLASV .:. .:: : :: .: . .:: : ..:::::.: NP_001 ---------------VGG--------QAQAV--TGSIQPLSAQALAGSLSSQQVYHLAAV 770 780 790 800 810 820 830 840 850 860 pF1KB3 RLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTF :::::: :::.:.:::.::::::::....::.:: ::::::::.::.:.:::::::...: NP_001 RLRDLCAKLDISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMAKVTKEDKSF 810 820 830 840 850 860 870 880 890 900 910 pF1KB3 QEIMKSYRNQPQANSHVYRSVLLK----------SIPREVVAYNKNINDDFEMIDCD-LE :.::. ::.:::: :.::::::.: : : ..: : : . . NP_001 QNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNKDRTSRDSSPVM 870 880 890 900 910 920 920 930 940 950 pF1KB3 DATKT---PDCSSGPV-------------KEERGDLIKFYNTIYVGRVKSFALKYDLANQ ...: :. ::.: .:::::::.:::.::. ..:.::.::. :: NP_001 RSSSTLPVPQPSSAPPTPTRLTGANSDMEEEERGDLIQFYNNIYIKQIKTFAMKYSQAN- 930 940 950 960 970 960 970 980 990 1000 1010 pF1KB3 DHMMDAPPLSPFPHIKQQPGSPRRI--SQQHSIYISPHKNGSGLTPRSALLYKFNGSPSK ::::::::.: .. :::::: ::.: .::::::: . :.:: ..: :..:::: NP_001 ---MDAPPLSPYPFVRT--GSPRRIQLSQNHPVYISPHKNETMLSPREKIFYYFSNSPSK 980 990 1000 1010 1020 1030 1020 1030 1040 1050 1060 pF1KB3 SLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH :..::.::: :: :::: : ... .::::::.: :: ..::.:::::...:..: NP_001 RLREINSMIRTGETPTKKRGILLEDGSESPAKRICPENHSALLRRLQDVANDRGSH 1040 1050 1060 1070 1080 1090 >>NP_001310538 (OMIM: 180203) retinoblastoma-like protei (1115 aa) initn: 3313 init1: 1045 opt: 2568 Z-score: 2790.0 bits: 528.0 E(85289): 1.2e-148 Smith-Waterman score: 3475; 49.4% identity (75.5% similar) in 1119 aa overlap (3-1068:26-1115) 10 20 30 pF1KB3 MFEDKPHAEGAAVVAAAG-----EALQALCQELNLDE :: .:: :: : . . .. ::..::.:: NP_001 MPSGGDQSPPPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQIQQRFDELCSRLNMDE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 GSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILR .. ::: :.. .. .:.:::. :::::.::::::::. :::.:: .::: :::::::. NP_001 AARAEAWDSYRSMSESYTLEGNDLHWLACALYVACRKSV-PTVSKGTVEGNYVSLTRILK 70 80 90 100 110 100 110 120 130 140 150 pF1KB3 SAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYE .. :::.::.::::: ::.::: .:::: ::::::: ::.:::::::::: :::. : : NP_001 CSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQE 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB3 EPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFAN : :. :.::::: ::.:...:.:::.::.:.:::: ::.:::::::::::: :::...: NP_001 EQPRQQRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGN 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB3 AIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFK :..: ::..:.::.:::: :::. : : .::::: :: :::::..::::::::..: NP_001 ALQCSNRKELVNPNFKGLSEDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWK 240 250 260 270 280 290 280 290 300 310 320 pF1KB3 PYISKLFDRKILKGEC-----LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAE ::: ::...:.:::. .:. ..: .. ::.:: ::::::.::..::::::: ::: NP_001 PYIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAE 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB3 EEIGTPRKFTRDTPLGKLTAQ-ANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITP ::::: . .. : ::. .... :::::.:.... :::::: ::..:. .:: NP_001 EEIGTLSRCL-NAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTP 360 370 380 390 400 410 390 400 410 420 430 440 pF1KB3 VASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQST :..::.:.:::.....::.::::..: .:...: :.:.. : . :: . : . ::. : NP_001 VSTATHSLSRLHTMLTGLRNAPSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHF-QPD 420 430 440 450 460 470 450 460 470 480 490 500 pF1KB3 DEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCL .. . ..: .....::.::::.::.:. :: .:: ::.: .:::: :::::.:::: NP_001 EDFSNCAKEIASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCL 480 490 500 510 520 530 510 520 530 540 550 560 pF1KB3 EIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESL :.: :.:. : .::.: :.... ..::::::: ::.:.:: :..:::::.::::::. : NP_001 EVVTFSYKPPGNFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHL 540 550 560 570 580 590 570 580 590 600 610 620 pF1KB3 AWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVR ::. .: ::: .. . :.:::::::. :.:.: .. . : ::: :: ::: NP_001 AWKPESPLWEKIRDNENRVPTCEEVMPPQNLERADEICIAG-------SPLTPRRVTEVR 600 610 620 630 640 650 630 640 650 660 670 680 pF1KB3 TDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGE-DPPKEMLMDKIITEGTKLKIAP .:.:.: :.. :: ....::::: :....:::: : : :.. . .. .: NP_001 ADTGGLGRSI--TSPTTLYDRYSSPPASTTRRRLFVENDSPSDGGTPGRMPPQPLVNAVP 660 670 680 690 700 690 700 710 720 730 740 pF1KB3 SSSITAENVSI--LPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTN- .....:.::. .:::::.::::: ::...:. ::::..:.::. : ::..:...:.. NP_001 VQNVSGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGG 710 720 730 740 750 760 750 760 770 pF1KB3 QESKVKSPVS-LTAHSLIGA----------------------SPKQTNLTKAQEVHSTGI : . : . .. :.:..: :. :: . ..: : :.. NP_001 QAQAVTGSIQPLSAQALAGSLSSQQVTGTTLQVPGQVAIQQISPGGQQQKQGQSVTSSS- 770 780 790 800 810 820 780 790 800 810 820 830 pF1KB3 NRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRH :::..:.::.::.:::::::.::::::: :::.:.:::.::::::::....::.:: ::: NP_001 NRPRKTSSLSLFFRKVYHLAAVRLRDLCAKLDISDELRKKIWTCFEFSIIQCPELMMDRH 830 840 850 860 870 880 840 850 860 870 880 890 pF1KB3 LDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIN :::::.::.:.:::: . . ..:. :.. ...: :: .. : :. ... NP_001 LDQLLMCAIYVMAKVYR-----SVLIKGKRKRRNSGSSDSRS--HQNSPTEL-NKDRTSR 890 900 910 920 930 900 910 920 930 940 pF1KB3 DDFEMIDCDLEDATKTPDCSSGPV-------------KEERGDLIKFYNTIYVGRVKSFA :. .. . .. .:. ::.: .:::::::.:::.::. ..:.:: NP_001 DSSPVMRSS--STLPVPQPSSAPPTPTRLTGANSDMEEEERGDLIQFYNNIYIKQIKTFA 940 950 960 970 980 990 950 960 970 980 990 1000 pF1KB3 LKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRI--SQQHSIYISPHKNGSGLTPRSALLY .::. :: ::::::::.: .. :::::: ::.: .::::::: . :.:: ..: NP_001 MKYSQAN----MDAPPLSPYPFVRT--GSPRRIQLSQNHPVYISPHKNETMLSPREKIFY 1000 1010 1020 1030 1040 1050 1010 1020 1030 1040 1050 1060 pF1KB3 KFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSE :..:::: :..::.::: :: :::: : ... .::::::.: :: ..::.:::::... NP_001 YFSNSPSKRLREINSMIRTGETPTKKRGILLEDGSESPAKRICPENHSALLRRLQDVAND 1060 1070 1080 1090 1100 1110 pF1KB3 RANH :..: NP_001 RGSH 1068 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:53:30 2016 done: Thu Nov 3 13:53:32 2016 Total Scan time: 14.430 Total Display time: 0.440 Function used was FASTA [36.3.4 Apr, 2011]